Monascuspiloin induces apoptosis and autophagic cell death in human prostate cancer cells via the akt and AMPK signaling pathways

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 29, 2012, Pages 7185-7193

  Chen, Rong Jane ^a   Hung, Chin Ming ^a   Chen, Yen Lin ^b   Wu, Ming Der ^b   Yuan, Gwo Fang ^b   Wang, Ying Jan ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

Author keywords

Akt mTOR; AMPK; apoptosis; autophagic cell death; Monascuspiloin; prostate cancer

Indexed keywords

AKT/MTOR; AMPK; AUTOPHAGIC CELLS; MONASCUSPILOIN; PROSTATE CANCERS;

DISEASES;

CELL DEATH;

ANTINEOPLASTIC AGENT; FUSED HETEROCYCLIC RINGS; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MONASCIN; MONASCUSPILOIN; MTOR PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TARGET OF RAPAMYCIN KINASE;

ANIMAL; APOPTOSIS; ARTICLE; AUTOPHAGY; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; CELL DEATH; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; MALE; MONASCUS; MOUSE; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; PROSTATE TUMOR; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CELL DEATH; CELL LINE, TUMOR; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MONASCUS; NEOPLASM TRANSPLANTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

MONASCUS; MUS MUSCULUS;

EID: 84864330818     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf3016927     Document Type: Article

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