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Volumn 79, Issue 6, 2012, Pages 1197-1205

Role of 5α-reductase inhibitors in prostate cancer prevention and treatment

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; CHOLESTEROL; DUTASTERIDE; FINASTERIDE; FLUTAMIDE; HYDROCORTISONE; IZONSTERIDE; KETOCONAZOLE; PLACEBO; PREGNANEDIONE; PROGESTERONE; PROSTATE SPECIFIC ANTIGEN; STEROID 5ALPHA REDUCTASE 2; TESTOSTERONE;

EID: 84861744513     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2012.01.024     Document Type: Review
Times cited : (37)

References (65)
  • 1
    • 0031018808 scopus 로고    scopus 로고
    • Immunocytochemical evidence for differential subcellular localization of 5 alpha-reductase isoenzymes in human tissues
    • G. Aumüller, W. Eicheler, H. Renneberg Immunocytochemical evidence for differential subcellular localization of 5 alpha-reductase isoenzymes in human tissues Acta Anat (Basel) 156 1996 241 252
    • (1996) Acta Anat (Basel) , vol.156 , pp. 241-252
    • Aumüller, G.1    Eicheler, W.2    Renneberg, H.3
  • 2
    • 77955057089 scopus 로고    scopus 로고
    • SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder
    • V. Cantagrel, D.J. Lefeber, B.G. Ng SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder Cell 142 2010 203 217
    • (2010) Cell , vol.142 , pp. 203-217
    • Cantagrel, V.1    Lefeber, D.J.2    Ng, B.G.3
  • 3
    • 79955796493 scopus 로고    scopus 로고
    • 5α-reductase type 3 expression in human benign and malignant tissues: A comparative analysis during prostate cancer progression
    • A. Godoy, E. Kawinski, Y. Li 5α-reductase type 3 expression in human benign and malignant tissues: a comparative analysis during prostate cancer progression Prostate 71 10 2011 1033 1046
    • (2011) Prostate , vol.71 , Issue.10 , pp. 1033-1046
    • Godoy, A.1    Kawinski, E.2    Li, Y.3
  • 5
    • 17644362707 scopus 로고    scopus 로고
    • Differential alterations in 5α-reductase type 1 and type 2 levels during development and progression of prostate cancer
    • DOI 10.1002/pros.20188
    • L.N. Thomas, C.B. Lazier, R. Gupta Differential alterations in 5α-reductase type 1 and type 2 levels during development and progression of prostate cancer Prostate 63 2005 231 239 (Pubitemid 40571057)
    • (2005) Prostate , vol.63 , Issue.3 , pp. 231-239
    • Thomas, L.N.1    Lazier, C.B.2    Gupta, R.3    Norman, R.W.4    Troyer, D.A.5    O'Brien, S.P.6    Rittmaster, R.S.7
  • 6
    • 18444398952 scopus 로고    scopus 로고
    • Long-term outcomes among localized prostate cancer survivors: Health-related quality-of-life changes after radical prostatectomy, external radiation, and brachytherapy
    • DOI 10.1200/JCO.2005.07.116
    • D.C. Miller, M.G. Sanda, R.L. Dunn Long-term outcomes among localized prostate cancer survivors: health-related quality-of-life changes after radical prostatectomy, external radiation, and brachytherapy J Clin Oncol 23 12 2005 2772 2780 (Pubitemid 46179467)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.12 , pp. 2772-2780
    • Miller, D.C.1    Sanda, M.G.2    Dunn, R.L.3    Montie, J.E.4    Pimentel, H.5    Sandler, H.M.6    McLaughlin, W.P.7    Wei, J.T.8
  • 7
    • 0027937517 scopus 로고
    • High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: An autopsy study of 249 cases
    • W.A. Sakr, D.J. Grignon, J.D. Crissman High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: an autopsy study of 249 cases In Vivo 8 1994 439 443
    • (1994) Vivo , vol.8 , pp. 439-443
    • Sakr, W.A.1    Grignon, D.J.2    Crissman, J.D.3
  • 10
    • 77950498003 scopus 로고    scopus 로고
    • Effect of dutasteride on the risk of prostate cancer
    • G.L. Andriole, D.G. Bostwick, O.W. Brawley Effect of dutasteride on the risk of prostate cancer N Engl J Med 362 2010 1192 1202
    • (2010) N Engl J Med , vol.362 , pp. 1192-1202
    • Andriole, G.L.1    Bostwick, D.G.2    Brawley, O.W.3
  • 11
    • 4444331484 scopus 로고    scopus 로고
    • Effect of dutasteride on the detection of prostate cancer in men with benign prostatic hyperplasia
    • G.L. Andriole, C. Roehrborn, C. Schulman Effect of dutasteride on the detection of prostate cancer in men with benign prostatic hyperplasia Urology 64 2004 537 541
    • (2004) Urology , vol.64 , pp. 537-541
    • Andriole, G.L.1    Roehrborn, C.2    Schulman, C.3
  • 12
    • 4444359330 scopus 로고    scopus 로고
    • Prostate cancer (CAP) detection in the medical therapy of prostatic symptoms (MTOPS) trial
    • G. Andriole, M. Bautista, D. Crawford Prostate cancer (CAP) detection in the medical therapy of prostatic symptoms (MTOPS) trial J Urol 169 suppl 2003 120
    • (2003) J Urol , vol.169 , Issue.SUPPL. , pp. 120
    • Andriole, G.1    Bautista, M.2    Crawford, D.3
  • 13
    • 0032146642 scopus 로고    scopus 로고
    • Treatment with finasteride preserves usefulness of prostate-specific antigen in the detection of prostate cancer: Results of a randomized, double-blind, placebo-controlled clinical trial PLESS Study Group. Proscar long-term efficacy and safety study
    • G.L. Andriole, H.A. Guess, J.I. Epstein Treatment with finasteride preserves usefulness of prostate-specific antigen in the detection of prostate cancer: results of a randomized, double-blind, placebo-controlled clinical trial PLESS Study Group. Proscar long-term efficacy and safety study Urology 52 1998 195 201
    • (1998) Urology , vol.52 , pp. 195-201
    • Andriole, G.L.1    Guess, H.A.2    Epstein, J.I.3
  • 15
    • 77949898163 scopus 로고    scopus 로고
    • Time trends and local variation in primary treatment of localized prostate cancer
    • M.R. Cooperberg, J.M. Broering, P.R. Carroll Time trends and local variation in primary treatment of localized prostate cancer J Clin Oncol 28 2010 1117 1123
    • (2010) J Clin Oncol , vol.28 , pp. 1117-1123
    • Cooperberg, M.R.1    Broering, J.M.2    Carroll, P.R.3
  • 16
    • 79957477272 scopus 로고    scopus 로고
    • Reduction in surgical and non-surgical interventions for prostate cancer with dutasteride treatment in the reduction by dutasteride of prostate cancer events (REDUCE) study
    • Milan
    • R. Rittmaster, F. Montorsi, M. Marberger Reduction in surgical and non-surgical interventions for prostate cancer with dutasteride treatment in the reduction by dutasteride of prostate cancer events (REDUCE) study Eur Soc Med Oncol 2010 Milan
    • (2010) Eur Soc Med Oncol
    • Rittmaster, R.1    Montorsi, F.2    Marberger, M.3
  • 19
    • 0037253594 scopus 로고    scopus 로고
    • Influence of prostate volume in the detection of prostate cancer
    • DOI 10.1016/S0090-4295(02)02103-9, PII S0090429502021039
    • J.B. Basillote, N.A. Armenakas, D.A. Hochberg Influence of prostate volume in the detection of prostate cancer Urology 61 2003 167 171 (Pubitemid 36151735)
    • (2003) Urology , vol.61 , Issue.1 , pp. 167-171
    • Basillote, J.B.1    Armenakas, N.A.2    Hochberg, D.A.3    Fracchia, J.A.4
  • 20
    • 34248138901 scopus 로고    scopus 로고
    • Quantifying the Impact of Prostate Volumes, Number of Biopsy Cores and 5α-Reductase Inhibitor Therapy on the Probability of Prostate Cancer Detection Using Mathematical Modeling
    • DOI 10.1016/j.juro.2007.01.116, PII S0022534707002546
    • R. Serfling, M. Shulman, G.L. Thompson Quantifying the impact of prostate volumes, number of biopsy cores and 5alpha-reductase inhibitor therapy on the probability of prostate cancer detection using mathematical modeling J Urol 177 2007 2352 2356 (Pubitemid 46726388)
    • (2007) Journal of Urology , vol.177 , Issue.6 , pp. 2352-2356
    • Serfling, R.1    Shulman, M.2    Thompson, G.L.3    Xiao, Z.4    Benaim, E.5    Roehrborn, C.G.6    Rittmaster, R.7
  • 23
    • 77955871814 scopus 로고    scopus 로고
    • Dutasteride and prostate cancer [letter to the editor]
    • G. Andriole, R.S. Rittmaster Dutasteride and prostate cancer [letter to the editor] N Engl J Med 363 2010 794 795
    • (2010) N Engl J Med , vol.363 , pp. 794-795
    • Andriole, G.1    Rittmaster, R.S.2
  • 24
    • 35648970584 scopus 로고    scopus 로고
    • How much does gleason grade of follow-up biopsy differ from that of initial biopsy in untreated, Gleason score 4-7, clinically localized prostate cancer?
    • DOI 10.1002/pros.20648
    • R. Choo, C. Danjoux, G. Morton How much does Gleason grade of follow-up biopsy differ from that of initial biopsy in untreated, Gleason score 4-7, clinically localized prostate cancer? Prostate 67 2007 1614 1620 (Pubitemid 350036947)
    • (2007) Prostate , vol.67 , Issue.15 , pp. 1614-1620
    • Choo, R.1    Danjoux, C.2    Morton, G.3    Szumacher, E.4    Sugar, L.5    Gardner, S.6    Kim, M.7    Choo, C.M.8    Klotz, L.9
  • 25
    • 70449536472 scopus 로고    scopus 로고
    • The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study
    • C.G. Roehrborn, P. Siami, J. Barkin The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study Eur Urol 57 2010 123 131
    • (2010) Eur Urol , vol.57 , pp. 123-131
    • Roehrborn, C.G.1    Siami, P.2    Barkin, J.3
  • 26
    • 85100506547 scopus 로고    scopus 로고
    • Dutasteride in localised prostate cancer management: The REDEEM randomised, double-blind, placebo-controlled trial
    • In press
    • Fleshner NE, Lucia MS, Egerdie B, et al. Dutasteride in localised prostate cancer management: the REDEEM randomised, double-blind, placebo-controlled trial. Lancet. In press.
    • Lancet
    • Fleshner, N.E.1    Lucia, M.S.2    Egerdie, B.3
  • 28
    • 0036754256 scopus 로고    scopus 로고
    • Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia
    • DOI 10.1016/S0090-4295(02)01905-2, PII S0090429502019052
    • C.G. Roehrborn, P. Boyle, J.C. Nickel Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia Urology 60 2002 434 441 (Pubitemid 35292169)
    • (2002) Urology , vol.60 , Issue.3 , pp. 434-441
    • Roehrborn, C.G.1    Boyle, P.2    Nickel J.Curtis3    Hoefner, K.4    Andriole, G.5
  • 30
    • 79957478279 scopus 로고    scopus 로고
    • Effect of dutasteride on the risk of prostate cancer [Editorial]
    • P.C. Walsh Effect of dutasteride on the risk of prostate cancer [Editorial] J Urol 194 2010 174 175
    • (2010) J Urol , vol.194 , pp. 174-175
    • Walsh, P.C.1
  • 31
    • 33646380585 scopus 로고    scopus 로고
    • Re: The prostate cancer prevention trial: Design, biases and interpretation of study results
    • Goodman P, Thompson I, Tangen C, et al. J Urol. 2006;176:2744
    • Walsh PC. Re: The prostate cancer prevention trial: design, biases and interpretation of study results. Goodman P, Thompson I, Tangen C, et al. J Urol. 2006;175:2234-2242. J Urol. 2006;176:2744.
    • (2006) J Urol. , vol.175 , pp. 2234-2242
    • Walsh, P.C.1
  • 32
    • 70249109675 scopus 로고    scopus 로고
    • Prostate cancer incidence among finasteride and alpha-blocker users in the Finnish prostate cancer screening trial
    • T.J. Murtola, T.L. Tammela, L. Määttänen Prostate cancer incidence among finasteride and alpha-blocker users in the Finnish prostate cancer screening trial Br J Cancer 101 2009 843 848
    • (2009) Br J Cancer , vol.101 , pp. 843-848
    • Murtola, T.J.1    Tammela, T.L.2    Määttänen, L.3
  • 33
    • 39749113833 scopus 로고    scopus 로고
    • Cost-effectiveness of prostate cancer chemoprevention: A quality of life-years analysis
    • DOI 10.1002/cncr.23276
    • R.S. Svatek, J.J. Lee, C.G. Roehrborn Cost-effectiveness of prostate cancer chemoprevention: A quality of life-years analysis Cancer 112 2008 1058 1065 (Pubitemid 351304590)
    • (2008) Cancer , vol.112 , Issue.5 , pp. 1058-1065
    • Svatek, R.S.1    Lee, J.J.2    Roehrborn, C.G.3    Lippman, S.M.4    Lotan, Y.5
  • 34
    • 34548217770 scopus 로고    scopus 로고
    • Low-Activity V89L Variant in SRD5A2 Is Associated with Aggressive Prostate Cancer Risk: An Explanation for the Adverse Effects Observed in Chemoprevention Trials Using 5-Alpha-Reductase Inhibitors
    • DOI 10.1016/j.eururo.2007.04.008, PII S030228380700471X
    • O. Cussenot, A.R. Azzouzi, N. Nicolaiew Low-activity V89L variant in SRD5A2 is associated with aggressive prostate cancer risk: an explanation for the adverse effects observed in chemoprevention trials using 5-alpha-reductase inhibitors Eur Urol 52 2007 1082 1089 (Pubitemid 47337033)
    • (2007) European Urology , vol.52 , Issue.4 , pp. 1082-1089
    • Cussenot, O.1    Azzouzi, A.-R.2    Nicolaiew, N.3    Mangin, P.4    Cormier, L.5    Fournier, G.6    Valeri, A.7    Cancel-Tassin, G.8
  • 36
    • 0035156454 scopus 로고    scopus 로고
    • V89L polymorphism of type-2, 5-alpha-reductase enzyme gene predicts prostate cancer presence and progression
    • 199-105
    • R.K. Nam, A. Toi, D. Vesprini V89L polymorphism of type-2, 5-alpha-reductase enzyme gene predicts prostate cancer presence and progression Urology 57 1 2001 199-105
    • (2001) Urology , vol.57 , Issue.1
    • Nam, R.K.1    Toi, A.2    Vesprini, D.3
  • 37
    • 62349141655 scopus 로고    scopus 로고
    • Use of 5α-reductase inhibitors for prostate cancer chemoprevention: American Society of Clinical Oncology/American Urological Association 2008 clinical practice guideline
    • B. Kramer, K. Hagerty, S. Justman Use of 5α-reductase inhibitors for prostate cancer chemoprevention: American Society of Clinical Oncology/American Urological Association 2008 clinical practice guideline J Urol 181 2009 1642 1657
    • (2009) J Urol , vol.181 , pp. 1642-1657
    • Kramer, B.1    Hagerty, K.2    Justman, S.3
  • 38
    • 0002532824 scopus 로고    scopus 로고
    • Finasteride effect on benign prostatic hyperplasia and prostate cancer: A comparative clinico-pathologic study of radical prostatectomies
    • F. Civantos, R.B. Watson, J.E. Pinto Finasteride effect on benign prostatic hyperplasia and prostate cancer: a comparative clinico-pathologic study of radical prostatectomies J Urol Pathol 6 1997 1 8
    • (1997) J Urol Pathol , vol.6 , pp. 1-8
    • Civantos, F.1    Watson, R.B.2    Pinto, J.E.3
  • 40
    • 58149193194 scopus 로고    scopus 로고
    • Effects of short-term finasteride on apoptotic factors and androgen receptors in prostate cancer cells
    • R. Bass, B. Perry, P. Langenstroer Effects of short-term finasteride on apoptotic factors and androgen receptors in prostate cancer cells J Urol 181 2009 615 620
    • (2009) J Urol , vol.181 , pp. 615-620
    • Bass, R.1    Perry, B.2    Langenstroer, P.3
  • 42
    • 12844279803 scopus 로고    scopus 로고
    • The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate
    • DOI 10.1016/j.urology.2004.08.042, PII S0090429504010155
    • K.A. Iczkowski, J. Qiu, J. Qian The dual 5alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate Urology 65 2005 76 82 (Pubitemid 40169609)
    • (2005) Urology , vol.65 , Issue.1 , pp. 76-82
    • Iczkowski, K.A.1    Qiu, J.2    Qian, J.3    Somerville, M.C.4    Rittmaster, R.S.5    Andriole, G.L.6    Bostwick, D.G.7
  • 45
    • 13544277666 scopus 로고    scopus 로고
    • Cell proliferation and apoptosis in prostate tumors and adjacent non-malignant prostate tissue in patients at different time-points after castration treatment
    • DOI 10.1002/pros.20139
    • N. Ohlson, P. Wikström, P. Stattin Cell proliferation and apoptosis in prostate tumors and adjacent non-malignant prostate tissue in patients at different time-points after castration treatment Prostate 62 4 2005 307 315 (Pubitemid 40224136)
    • (2005) Prostate , vol.62 , Issue.4 , pp. 307-315
    • Ohlson, N.1    Wikstrom, P.2    Stattin, P.3    Bergh, A.4
  • 46
    • 0242495783 scopus 로고    scopus 로고
    • Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy
    • DOI 10.1016/S0090-4295(03)00667-8
    • A.B. Barqawi, J.W. Moul, A. Ziada Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy Urology 62 2003 872 876 (Pubitemid 37421234)
    • (2003) Urology , vol.62 , Issue.5 , pp. 872-876
    • Barqawi, A.B.1    Moul, J.W.2    Ziada, A.3    Handel, L.4    Crawford, E.D.5
  • 47
    • 68049140915 scopus 로고    scopus 로고
    • Combined low-dose flutamide plus finasteride vs low-dose flutamide monotherapy for recurrent prostate cancer: A comparative analysis of two phase II trials with a long-term follow-up
    • L.L. Bañez, G.W. Blake, D.G. McLeod Combined low-dose flutamide plus finasteride vs low-dose flutamide monotherapy for recurrent prostate cancer: a comparative analysis of two phase II trials with a long-term follow-up BJU Int 104 2009 310 314
    • (2009) BJU Int , vol.104 , pp. 310-314
    • Bañez, L.L.1    Blake, G.W.2    McLeod, D.G.3
  • 48
    • 0038353581 scopus 로고    scopus 로고
    • Finasteride and flutamide therapy in patients with advanced prostate cancer: Response to subsequent castration and long-term follow-up
    • DOI 10.1016/S0090-4295(03)00145-6
    • W.K. Oh, J. Manola, L. Bittmann Finasteride and flutamide therapy in patients with advanced prostate cancer: response to subsequent castration and long-term follow-up Urology 62 2003 99 104 (Pubitemid 36802080)
    • (2003) Urology , vol.62 , Issue.1 , pp. 99-104
    • Oh, W.K.1    Manola, J.2    Bittmann, L.3    Brufsky, A.4    Kaplan, I.D.5    Smith, M.R.6    Kaufman, D.S.7    Kantoff, P.W.8
  • 49
    • 0028843851 scopus 로고
    • Treatment with finasteride following radical prostatectomy for prostate cancer
    • G. Andriole, M. Lieber, J. smith Treatment with finasteride following radical prostatectomy for prostate cancer Urology 45 3 1995 491 497
    • (1995) Urology , vol.45 , Issue.3 , pp. 491-497
    • Andriole, G.1    Lieber, M.2    Smith, J.3
  • 50
    • 84861720604 scopus 로고    scopus 로고
    • Dutasteride monotherapy in men with serologic relapse following radical therapy for adenocarcinoma of the prostate: A pilot study
    • [Epub ahead of print]
    • M. Perotti, R. Jain, L. Abriel Dutasteride monotherapy in men with serologic relapse following radical therapy for adenocarcinoma of the prostate: A pilot study Urol Oncol Semin Orig Inves 2010 [Epub ahead of print]
    • (2010) Urol Oncol Semin Orig Inves
    • Perotti, M.1    Jain, R.2    Abriel, L.3
  • 52
    • 65049090443 scopus 로고    scopus 로고
    • Intermittent androgen deprivation for locally advanced and metastatic prostate cancer: Results from a randomised phase 3 study of the South European Uroncological Group
    • F.E. Calais da Silva, A.V. Bono, P. Whelan Intermittent androgen deprivation for locally advanced and metastatic prostate cancer: results from a randomised phase 3 study of the South European Uroncological Group Eur Urol 55 2009 1269 1277
    • (2009) Eur Urol , vol.55 , pp. 1269-1277
    • Calais Da Silva, F.E.1    Bono, A.V.2    Whelan, P.3
  • 53
    • 80053212143 scopus 로고    scopus 로고
    • A phase III randomized trial comparing intermittent versus continuous androgen suppression for patients with PSA progression after radical therapy: NCIC CTG PR.7/SWOG JPR.7/CTSU JPR.7/UK intercontinental trial CRUKE/01/013
    • L. Klotz, C. O'Callaghan, K. Ding A phase III randomized trial comparing intermittent versus continuous androgen suppression for patients with PSA progression after radical therapy: NCIC CTG PR.7/SWOG JPR.7/CTSU JPR.7/UK intercontinental trial CRUKE/01/013 JCO 29 suppl 2011 3
    • (2011) JCO , vol.29 , Issue.SUPPL. , pp. 3
    • Klotz, L.1    O'Callaghan, C.2    Ding, K.3
  • 54
    • 33645341444 scopus 로고    scopus 로고
    • Enhancement of intermittent androgen ablation by "off-cycle" maintenance with finasteride in LNCaP prostate cancer xenograft model
    • S.E. Eggener, J.A. Stern, P.M. Jain Enhancement of intermittent androgen ablation by "off-cycle" maintenance with finasteride in LNCaP prostate cancer xenograft model Prostate 66 5 2006 495 502
    • (2006) Prostate , vol.66 , Issue.5 , pp. 495-502
    • Eggener, S.E.1    Stern, J.A.2    Jain, P.M.3
  • 55
    • 73449119262 scopus 로고    scopus 로고
    • Prolongation of off-cycle interval by finasteride is not associated with survival improvement in intermittent androgen deprivation therapy in LNCaP tumor model
    • Y. Wang, S. Gupta, V. Hua Prolongation of off-cycle interval by finasteride is not associated with survival improvement in intermittent androgen deprivation therapy in LNCaP tumor model Prostate 70 2010 147 154
    • (2010) Prostate , vol.70 , pp. 147-154
    • Wang, Y.1    Gupta, S.2    Hua, V.3
  • 56
    • 33645970181 scopus 로고    scopus 로고
    • Intermittent use of testosterone inactivating pharmaceuticals using finasteride prolongs the time off period
    • M.C. Scholz, R.I. Jennrich, S.B. Strum Intermittent use of testosterone inactivating pharmaceuticals using finasteride prolongs the time off period J Urol 175 5 2006 1673 1678
    • (2006) J Urol , vol.175 , Issue.5 , pp. 1673-1678
    • Scholz, M.C.1    Jennrich, R.I.2    Strum, S.B.3
  • 57
    • 79958057259 scopus 로고    scopus 로고
    • Prostate cancer: Finasteride extends PSA doubling time during intermittent hormone therapy
    • J.A. Locke, N. Bruchovsky Prostate cancer: finasteride extends PSA doubling time during intermittent hormone therapy Can J Urol 17 3 2010 5162 5169
    • (2010) Can J Urol , vol.17 , Issue.3 , pp. 5162-5169
    • Locke, J.A.1    Bruchovsky, N.2
  • 59
    • 27644452640 scopus 로고    scopus 로고
    • Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
    • DOI 10.1158/1078-0432.CCR-05-0525
    • M.A. Titus, M.J. Schell, F.B. Lih Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer Clin Cancer Res 11 2005 4653 4657 (Pubitemid 41557182)
    • (2005) Clinical Cancer Research , vol.11 , Issue.13 , pp. 4653-4657
    • Titus, M.A.1    Schell, M.J.2    Lih, F.B.3    Tomer, K.B.4    Mohler, J.L.5
  • 60
    • 33645056171 scopus 로고    scopus 로고
    • Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
    • M. Stanbrough, G.J. Bubley, K. Ross Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer Cancer Res 66 2006 2815 2825
    • (2006) Cancer Res , vol.66 , pp. 2815-2825
    • Stanbrough, M.1    Bubley, G.J.2    Ross, K.3
  • 61
    • 51049098138 scopus 로고    scopus 로고
    • Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
    • J.A. Locke, E.S. Guns, A.A. Lubik Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer Cancer Res 68 2008 6407 6415
    • (2008) Cancer Res , vol.68 , pp. 6407-6415
    • Locke, J.A.1    Guns, E.S.2    Lubik, A.A.3
  • 63
    • 58149203191 scopus 로고    scopus 로고
    • Phase II study of dutasteride in recurrent prostate cancer during androgen-deprivation therapy
    • S. Shah, D. Trump, O. Sartor Phase II study of dutasteride in recurrent prostate cancer during androgen-deprivation therapy J Uro 181 2009 621 626
    • (2009) J Uro , vol.181 , pp. 621-626
    • Shah, S.1    Trump, D.2    Sartor, O.3
  • 64
    • 70449092013 scopus 로고    scopus 로고
    • Activity of dutasteride plus ketoconazole in castration-refractory prostate cancer after progression on ketoconazole alone
    • O. Sartor, M. Nakabayashi, M.E. Taplin Activity of dutasteride plus ketoconazole in castration-refractory prostate cancer after progression on ketoconazole alone Clin Genitourin Cancer 7 3 2009 E90 E92
    • (2009) Clin Genitourin Cancer , vol.7 , Issue.3
    • Sartor, O.1    Nakabayashi, M.2    Taplin, M.E.3
  • 65
    • 72549108829 scopus 로고    scopus 로고
    • Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer
    • M.E. Taplin, M.M. Regan, Y.J. Ko Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer Clin Cancer Res 15 22 2009 7099 7105
    • (2009) Clin Cancer Res , vol.15 , Issue.22 , pp. 7099-7105
    • Taplin, M.E.1    Regan, M.M.2    Ko, Y.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.