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Volumn 8, Issue 1, 2013, Pages

Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma

Author keywords

Nasopharyngeal carcinoma; p53 codon 72 polymorphism; pAkt; Radiotherapy

Indexed keywords

PARAFFIN; PROTEIN KINASE B; PROTEIN P53;

EID: 84877264216     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-8-117     Document Type: Article
Times cited : (11)

References (50)
  • 1
    • 0002371005 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma
    • Beijing, China: People's Medical Press, Gun GY
    • Min HQ. Nasopharyngeal carcinoma. Epidemiology 1996, 280-285. Beijing, China: People's Medical Press, Gun GY.
    • (1996) Epidemiology , pp. 280-285
    • Min, H.Q.1
  • 2
    • 0036275317 scopus 로고    scopus 로고
    • Combined chemoradiation versus radiation therapy alone in locally advanced nasopharyngeal carcinoma:results of ameta-analysis of 1,528 patients from six randomized trials
    • 10.1097/00000421-200206000-00002, 12040275
    • Huncharek M, Kupelnick B. Combined chemoradiation versus radiation therapy alone in locally advanced nasopharyngeal carcinoma:results of ameta-analysis of 1,528 patients from six randomized trials. Am J Clin Oncol 2002, 25:219-223. 10.1097/00000421-200206000-00002, 12040275.
    • (2002) Am J Clin Oncol , vol.25 , pp. 219-223
    • Huncharek, M.1    Kupelnick, B.2
  • 3
    • 16544393582 scopus 로고    scopus 로고
    • The additional value of chemotherapy to radiotherapy in locally advanced nasopharyngeal carcinoma: a meta-analysis of the published literature
    • 10.1200/JCO.2004.10.074, 15542811
    • Langendijk JA, Leemans CR, Buter J, Berkhof J, Slotman BJ. The additional value of chemotherapy to radiotherapy in locally advanced nasopharyngeal carcinoma: a meta-analysis of the published literature. J Clin Oncol 2004, 22:4604-4612. 10.1200/JCO.2004.10.074, 15542811.
    • (2004) J Clin Oncol , vol.22 , pp. 4604-4612
    • Langendijk, J.A.1    Leemans, C.R.2    Buter, J.3    Berkhof, J.4    Slotman, B.J.5
  • 4
    • 0032907105 scopus 로고    scopus 로고
    • Two polymorphic variants of wild-type p53 differ biochemically and biologically
    • 116039, 9891044
    • Thomas M, Kalita A, Labrecque S, Pim D, Banks L, Matlashewski G. Two polymorphic variants of wild-type p53 differ biochemically and biologically. Mol Cell Biol 1999, 19:1092-1100. 116039, 9891044.
    • (1999) Mol Cell Biol , vol.19 , pp. 1092-1100
    • Thomas, M.1    Kalita, A.2    Labrecque, S.3    Pim, D.4    Banks, L.5    Matlashewski, G.6
  • 5
    • 0037372005 scopus 로고    scopus 로고
    • The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
    • 10.1038/ng1093, 12567188
    • Dumont P, Leu J, Della Pietra AC, George DL, Murphy M. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet 2003, 33:357-365. 10.1038/ng1093, 12567188.
    • (2003) Nat Genet , vol.33 , pp. 357-365
    • Dumont, P.1    Leu, J.2    Della Pietra, A.C.3    George, D.L.4    Murphy, M.5
  • 7
    • 0346121357 scopus 로고    scopus 로고
    • P53 polymorphic variants at codon 72 exert different effects on cell cycle progression
    • 10.1002/ijc.11548, 14639602
    • Pim D, Banks L. p53 polymorphic variants at codon 72 exert different effects on cell cycle progression. Int J Cancer 2004, 108:196-199. 10.1002/ijc.11548, 14639602.
    • (2004) Int J Cancer , vol.108 , pp. 196-199
    • Pim, D.1    Banks, L.2
  • 11
  • 15
    • 67650085193 scopus 로고    scopus 로고
    • TP53 codon 72 polymorphism contributes to nasopharyngeal cancer susceptibility: a meta-analysis
    • 10.1016/j.arcmed.2009.03.006, 19608020
    • Zhuo XL, Cai L, Xiang ZL, Zhuo WL, Wang Y, Zhang XY. TP53 codon 72 polymorphism contributes to nasopharyngeal cancer susceptibility: a meta-analysis. Arch Med Res 2009, 40:299-305. 10.1016/j.arcmed.2009.03.006, 19608020.
    • (2009) Arch Med Res , vol.40 , pp. 299-305
    • Zhuo, X.L.1    Cai, L.2    Xiang, Z.L.3    Zhuo, W.L.4    Wang, Y.5    Zhang, X.Y.6
  • 16
    • 77749289244 scopus 로고    scopus 로고
    • PTEN/pAkt/p53 signaling pathway correlates with the radioresponse of non-small cell lung cancer
    • Jung IL, Kang HJ, Kim KC, Kim IG. PTEN/pAkt/p53 signaling pathway correlates with the radioresponse of non-small cell lung cancer. Int J Mol Med 2010, 25:517-523.
    • (2010) Int J Mol Med , vol.25 , pp. 517-523
    • Jung, I.L.1    Kang, H.J.2    Kim, K.C.3    Kim, I.G.4
  • 17
    • 38749093269 scopus 로고    scopus 로고
    • Overexpression of phospho-Akt correlates with phosphorylation of EGF receptor, FKHR and BAD in nasopharyngeal carcinoma
    • Yip WK, Leong VC, Abdullah MA, Yusoff S, Seow HF. Overexpression of phospho-Akt correlates with phosphorylation of EGF receptor, FKHR and BAD in nasopharyngeal carcinoma. Oncol Rep 2008, 19:319-328.
    • (2008) Oncol Rep , vol.19 , pp. 319-328
    • Yip, W.K.1    Leong, V.C.2    Abdullah, M.A.3    Yusoff, S.4    Seow, H.F.5
  • 18
    • 32044435126 scopus 로고    scopus 로고
    • Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways
    • 10.1101/gad.1363206, 16452501
    • Levine AJ, Feng Z, Mak TW, You H, Jin S. Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways. Genes Dev 2006, 20:267-275. 10.1101/gad.1363206, 16452501.
    • (2006) Genes Dev , vol.20 , pp. 267-275
    • Levine, A.J.1    Feng, Z.2    Mak, T.W.3    You, H.4    Jin, S.5
  • 19
    • 85047699328 scopus 로고    scopus 로고
    • Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis
    • 10.1038/sj.onc.1205181, 11850850
    • Gottlieb TM, Leal JF, Seger R, Taya Y, Oren M. Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis. Oncogene 2002, 21:1299-1303. 10.1038/sj.onc.1205181, 11850850.
    • (2002) Oncogene , vol.21 , pp. 1299-1303
    • Gottlieb, T.M.1    Leal, J.F.2    Seger, R.3    Taya, Y.4    Oren, M.5
  • 21
    • 3242883729 scopus 로고    scopus 로고
    • The p53 response to DNA damage
    • Meek DW. The p53 response to DNA damage. DNA Repair (Amst) 2004, 3:1049-1056.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1049-1056
    • Meek, D.W.1
  • 22
    • 45549104364 scopus 로고    scopus 로고
    • P53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK
    • 10.1073/pnas.0703423105, 2409394, 18505846
    • Boehme KA, Kulikov R, Blattner C. p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK. Proc Natl Acad Sci USA 2008, 105:7785-7790. 10.1073/pnas.0703423105, 2409394, 18505846.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7785-7790
    • Boehme, K.A.1    Kulikov, R.2    Blattner, C.3
  • 23
    • 77954064967 scopus 로고    scopus 로고
    • Essential role of PI3-kinase pathway in p53-mediated transcription: Implications in cancer chemotherapy
    • Suvasini R, Somasundaram K. Essential role of PI3-kinase pathway in p53-mediated transcription: Implications in cancer chemotherapy. Oncogene Oncogene 2010, 29:3605-3618.
    • (2010) Oncogene Oncogene , vol.29 , pp. 3605-3618
    • Suvasini, R.1    Somasundaram, K.2
  • 24
    • 22544466382 scopus 로고    scopus 로고
    • Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity
    • 10.1128/MCB.25.15.6592-6602.2005, 1190347, 16024795
    • Huang WC, Chen CC. Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. Mol Cell Biol 2005, 25:6592-6602. 10.1128/MCB.25.15.6592-6602.2005, 1190347, 16024795.
    • (2005) Mol Cell Biol , vol.25 , pp. 6592-6602
    • Huang, W.C.1    Chen, C.C.2
  • 25
    • 3242674366 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: correlation with angiogenesis and prognostic significance
    • 10.1007/s00401-004-0860-0, 15088099
    • Hara A, Okayasu I. Cyclooxygenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: correlation with angiogenesis and prognostic significance. Acta Neuropathol 2004, 108:43-48. 10.1007/s00401-004-0860-0, 15088099.
    • (2004) Acta Neuropathol , vol.108 , pp. 43-48
    • Hara, A.1    Okayasu, I.2
  • 27
    • 39749118523 scopus 로고    scopus 로고
    • Influence of the TP53 codon 72 polymorphism on the cellular responses to X-irradiation in fibroblasts from nonagenarians
    • 10.1016/j.mad.2007.12.006, 18272203
    • Den Reijer PM, Maier AB, Westendorp RG, Van Heemst D. Influence of the TP53 codon 72 polymorphism on the cellular responses to X-irradiation in fibroblasts from nonagenarians. Mech Ageing Dev 2008, 129:175-182. 10.1016/j.mad.2007.12.006, 18272203.
    • (2008) Mech Ageing Dev , vol.129 , pp. 175-182
    • Den Reijer, P.M.1    Maier, A.B.2    Westendorp, R.G.3    Van Heemst, D.4
  • 28
    • 0030795068 scopus 로고    scopus 로고
    • Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein
    • Landers JE, Cassel SL, George DL. Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein. Cancer Res 1997, 57:3562-3568.
    • (1997) Cancer Res , vol.57 , pp. 3562-3568
    • Landers, J.E.1    Cassel, S.L.2    George, D.L.3
  • 31
    • 0035096488 scopus 로고    scopus 로고
    • Inactivate the remaining p53 allele or the alternate p73? Preferential selection of the Arg72 polymorphism in cancers with recessive p53 mutants but not transdominant mutants
    • 10.1093/carcin/22.3.515, 11238194
    • Tada M, Furuuchi K, Kaneda M, Matsumoto J, Takahashi M, Hirai A, Mitsumoto Y, Iggo RD, Moriuchi T. Inactivate the remaining p53 allele or the alternate p73? Preferential selection of the Arg72 polymorphism in cancers with recessive p53 mutants but not transdominant mutants. Carcinogenesis 2001, 22:515-517. 10.1093/carcin/22.3.515, 11238194.
    • (2001) Carcinogenesis , vol.22 , pp. 515-517
    • Tada, M.1    Furuuchi, K.2    Kaneda, M.3    Matsumoto, J.4    Takahashi, M.5    Hirai, A.6    Mitsumoto, Y.7    Iggo, R.D.8    Moriuchi, T.9
  • 32
    • 0036433743 scopus 로고    scopus 로고
    • Genetic and epigenetic changes in nasopharyngeal carcinoma
    • 10.1016/S1044579X02000883, 12450731
    • Lo KW, Huang DP. Genetic and epigenetic changes in nasopharyngeal carcinoma. Semin Cancer Biol 2002, 12:451-462. 10.1016/S1044579X02000883, 12450731.
    • (2002) Semin Cancer Biol , vol.12 , pp. 451-462
    • Lo, K.W.1    Huang, D.P.2
  • 35
    • 33750520339 scopus 로고    scopus 로고
    • Detection of EBV and HPV in nasopharyngeal carcinoma by in situ hybridization
    • 10.1016/j.yexmp.2006.04.006, 16787643
    • Mirzamani N, Salehian P, Farhadi M, Tehran EA. Detection of EBV and HPV in nasopharyngeal carcinoma by in situ hybridization. Exp Mol Pathol 2006, 81:231-234. 10.1016/j.yexmp.2006.04.006, 16787643.
    • (2006) Exp Mol Pathol , vol.81 , pp. 231-234
    • Mirzamani, N.1    Salehian, P.2    Farhadi, M.3    Tehran, E.A.4
  • 37
    • 0030847899 scopus 로고    scopus 로고
    • Cell proliferation as an independent predictor of survival for patients with advanced nasopharyngeal carcinoma
    • Faccioli S, Cavicchi O, Caliceti U, Rinaldi Ceroni A, Chieco P. Cell proliferation as an independent predictor of survival for patients with advanced nasopharyngeal carcinoma. Mod Pathol 1997, 10:884-894.
    • (1997) Mod Pathol , vol.10 , pp. 884-894
    • Faccioli, S.1    Cavicchi, O.2    Caliceti, U.3    Rinaldi Ceroni, A.4    Chieco, P.5
  • 38
    • 0034047788 scopus 로고    scopus 로고
    • Prognostic value of p53, proliferating cell nuclear antigen, and Ki-67 expression in undifferentiated nasopharyngeal carcinomas
    • 10.1016/S0194-5998(00)70016-7, 10828801
    • Genc E, Hosal AS, Gedikoglu G, Ozyar E, Sozeri B. Prognostic value of p53, proliferating cell nuclear antigen, and Ki-67 expression in undifferentiated nasopharyngeal carcinomas. Otolaryngol Head Neck Surg 2000, 122:868-873. 10.1016/S0194-5998(00)70016-7, 10828801.
    • (2000) Otolaryngol Head Neck Surg , vol.122 , pp. 868-873
    • Genc, E.1    Hosal, A.S.2    Gedikoglu, G.3    Ozyar, E.4    Sozeri, B.5
  • 40
    • 0031813002 scopus 로고    scopus 로고
    • Bcl-2 and proliferating cell nuclear antigen (PCNA) expression correlates with subsequent local recurrence in nasopharyngeal carcinomas
    • Tsai ST, Jin YT, Leung HW, Wang ST, Tsao CJ, Su IJ. Bcl-2 and proliferating cell nuclear antigen (PCNA) expression correlates with subsequent local recurrence in nasopharyngeal carcinomas. Anticancer Res 1998, 18:2849-2854.
    • (1998) Anticancer Res , vol.18 , pp. 2849-2854
    • Tsai, S.T.1    Jin, Y.T.2    Leung, H.W.3    Wang, S.T.4    Tsao, C.J.5    Su, I.J.6
  • 41
    • 10744230953 scopus 로고    scopus 로고
    • Prognostic significance of tumor angiogenesis, Ki 67, p53 oncoprotein, epidermal growth factor receptor and HER2 receptor protein expression in undifferentiated nasopharyngeal carcinoma-a prospective study
    • 10.1002/hed.10307, 12966511
    • Ma BB, Poon TC, To KF, Zee B, Mo FK, Chan CM, Ho S, Teo PM, Johnson PJ, Chan AT. Prognostic significance of tumor angiogenesis, Ki 67, p53 oncoprotein, epidermal growth factor receptor and HER2 receptor protein expression in undifferentiated nasopharyngeal carcinoma-a prospective study. Head Neck 2003, 25:864-872. 10.1002/hed.10307, 12966511.
    • (2003) Head Neck , vol.25 , pp. 864-872
    • Ma, B.B.1    Poon, T.C.2    To, K.F.3    Zee, B.4    Mo, F.K.5    Chan, C.M.6    Ho, S.7    Teo, P.M.8    Johnson, P.J.9    Chan, A.T.10
  • 42
    • 0031753716 scopus 로고    scopus 로고
    • Expression of bcl-2-, p53, and Ki-67 and outcome of patients with primary nasopharyngeal carcinomas following DNA-damaging treatment
    • 10.1002/(SICI)1097-0347(199810)20:7<640::AID-HED11>3.0.CO;2-K, 9744466
    • Masuda M, Shinokuma A, Hirakawa N, Nakashima T, Komiyama S. Expression of bcl-2-, p53, and Ki-67 and outcome of patients with primary nasopharyngeal carcinomas following DNA-damaging treatment. Head Neck 1998, 20:640-644. 10.1002/(SICI)1097-0347(199810)20:7<640::AID-HED11>3.0.CO;2-K, 9744466.
    • (1998) Head Neck , vol.20 , pp. 640-644
    • Masuda, M.1    Shinokuma, A.2    Hirakawa, N.3    Nakashima, T.4    Komiyama, S.5
  • 43
    • 33745684526 scopus 로고    scopus 로고
    • The prognostic value of proliferating cell nuclear antigen (PCNA) and p53 protein expression in patients with advanced nasopharyngeal carcinoma
    • 10.1080/00016480500469545, 16803719
    • Wang LF, Chai CY, Kuo WR, Tai CF, Lee KW, Ho KY. The prognostic value of proliferating cell nuclear antigen (PCNA) and p53 protein expression in patients with advanced nasopharyngeal carcinoma. Acta Otolaryngol 2006, 126:769-774. 10.1080/00016480500469545, 16803719.
    • (2006) Acta Otolaryngol , vol.126 , pp. 769-774
    • Wang, L.F.1    Chai, C.Y.2    Kuo, W.R.3    Tai, C.F.4    Lee, K.W.5    Ho, K.Y.6
  • 44
    • 0030820557 scopus 로고    scopus 로고
    • P21/waf1 protein expression in nasopharyngeal carcinoma. Comparative study with PCNA, p53 and MDM-2 protein expression
    • Kouvidou C, Stefanaki K, Dai Y, Tzardi M, Koutsoubi K, Darivianaki K. P21/waf1 protein expression in nasopharyngeal carcinoma. Comparative study with PCNA, p53 and MDM-2 protein expression. Anticancer Res 1997, 17:2615-2619.
    • (1997) Anticancer Res , vol.17 , pp. 2615-2619
    • Kouvidou, C.1    Stefanaki, K.2    Dai, Y.3    Tzardi, M.4    Koutsoubi, K.5    Darivianaki, K.6
  • 45
    • 0141529779 scopus 로고    scopus 로고
    • 14-3-3 sigma positively regulates p53 and suppresses tumor growth
    • 10.1128/MCB.23.20.7096-7107.2003, 230310, 14517281
    • Yang HY, Wen YY, Chen CH, Lozano G, Lee MH. 14-3-3 sigma positively regulates p53 and suppresses tumor growth. Mol Cell Biol 2003, 23:7096-7107. 10.1128/MCB.23.20.7096-7107.2003, 230310, 14517281.
    • (2003) Mol Cell Biol , vol.23 , pp. 7096-7107
    • Yang, H.Y.1    Wen, Y.Y.2    Chen, C.H.3    Lozano, G.4    Lee, M.H.5
  • 46
    • 33644970995 scopus 로고    scopus 로고
    • 14-3-3sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma
    • Yang H, Zhao R, Lee MH. 14-3-3sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma. Mol Cancer Ther 2006, 5:253-860.
    • (2006) Mol Cancer Ther , vol.5 , pp. 253-860
    • Yang, H.1    Zhao, R.2    Lee, M.H.3
  • 48
    • 67849083376 scopus 로고    scopus 로고
    • The PI3-K/AKT-pathway and radiation resistance mechanisms in non-small cell lung cancer
    • 10.1097/JTO.0b013e3181a1084f, 19404218
    • Schuurbiers OC, Kaanders JH, van der Heijden HF, Dekhuijzen RP, Oyen WJ, Bussink J. The PI3-K/AKT-pathway and radiation resistance mechanisms in non-small cell lung cancer. J Thorac Oncol 2009, 4:761-767. 10.1097/JTO.0b013e3181a1084f, 19404218.
    • (2009) J Thorac Oncol , vol.4 , pp. 761-767
    • Schuurbiers, O.C.1    Kaanders, J.H.2    van der Heijden, H.F.3    Dekhuijzen, R.P.4    Oyen, W.J.5    Bussink, J.6
  • 49
    • 4944255743 scopus 로고    scopus 로고
    • Post-translational modification of p53 in tumorigenesis
    • 10.1038/nrc1455, 15510160
    • Bode AM, Dong Z. Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer 2004, 4:793-805. 10.1038/nrc1455, 15510160.
    • (2004) Nat Rev Cancer , vol.4 , pp. 793-805
    • Bode, A.M.1    Dong, Z.2


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