Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein

Journal of Biological Chemistry

Volumn 286, Issue 20, 2011, Pages 18251-18260

  Ozeki, Chikako ^a,b   Sawai, Yuichiro ^a,b   Shibata, Tatsuhiro ^a   Kohno, Takashi ^a   Okamoto, Koji ^a   Yokota, Jun ^a   Tashiro, Fumio ^b   Tanuma, Sei Ichi ^b   Sakai, Ryuichi ^a   Kawase, Tatsuya ^a,b   Kitabayashi, Issay ^a   Taya, Yoichi ^a,c   Ohki, Rieko ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER RISK; CLINICAL OUTCOME; GENETIC FACTORS; N-TERMINALS; P53 PROTEIN; POLYMORPHIC VARIANT; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN STRUCTURES;

ARGININE; DEGRADATION; DISEASES;

PHOSPHORYLATION;

PROTEIN P53;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER SUSCEPTIBILITY; CARBOXY TERMINAL SEQUENCE; CODON; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM; UBIQUITINATION;

CELL LINE; CODON; GENETIC PREDISPOSITION TO DISEASE; HUMANS; NEOPLASMS; PHOSPHORYLATION; POLYMORPHISM, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-MDM2; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79955971802     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.208587     Document Type: Article

References (28)

1. Vogelstein, B., Lane, D., and Levine, A. J. (2000) Nature 408, 307-310
2. Vousden, K. H., and Lu, X. (2002) Nat. Rev. Cancer 2, 594-604
3. Braithwaite, A. W., and Prives, C. L. (2006) Cell Death Differ. 13, 877-880
4. Prives, C. (1998) Cell 95, 5-8
5. Xu, Y. (2003) Cell Death Differ. 10, 400-403
6. Bode, A. M., and Dong, Z. (2004) Nat. Rev. Cancer 4, 793-805
7. Oda, K., Arakawa, H., Tanaka, T., Matsuda, K., Tanikawa, C., Mori, T., Nishimori, H., Tamai, K., Tokino, T., Nakamura, Y., and Taya, Y. (2000) Cell 102, 849-862
8. Kawase, T., Ichikawa, H., Ohta, T., Nozaki, N., Tashiro, F., Ohki, R., and Taya, Y. (2008) Oncogene 27, 3797-3810
9. Kawase, T., Ohki, R., Shibata, T., Tsutsumi, S., Kamimura, N., Inazawa, J., Ohta, T., Ichikawa, H., Aburatani, H., Tashiro, F., and Taya, Y. (2009) Cell 136, 535-550
10. Unger, T., Sionov, R. V., Moallem, E., Yee, C. L., Howley, P. M., Oren, M., and Haupt, Y. (1999) Oncogene 18, 3205-3212
11. Toledo, F., and Wahl, G. M. (2006) Nat. Rev. Cancer 6, 909-923
12. Zilfou, J. T., Hoffman, W. H., Sank, M., George, D. L., and Murphy, M. (2001) Mol. Cell. Biol. 21, 3974-3985
13. Bergamaschi, D., Samuels, Y., Sullivan, A., Zvelebil, M., Breyssens, H., Bisso, A., Del Sal, G., Syed, N., Smith, P., Gasco, M., Crook, T., and Lu, X. (2006) Nat. Genet. 38, 1133-1141
14. Harris, N., Brill, E., Shohat, O., Prokocimer, M., Wolf, D., Arai, N., and Rotter, V. (1986) Mol. Cell. Biol. 6, 4650-4656
15. Murphy, M. E. (2006) Cell Death Differ. 13, 916-920
16. Matlashewski, G. J., Tuck, S., Pim, D., Lamb, P., Schneider, J., and Crawford, L. V. (1987) Mol. Cell. Biol. 7, 961-963
17. Soussi, T., and Wiman, K. G. (2007) Cancer Cell 12, 303-312
18. Fan, R., Wu, M. T., Miller, D., Wain, J. C., Kelsey, K. T., Wiencke, J. K., and Christiani, D. C. (2000) Cancer Epidemiol. Biomarkers Prev. 9, 1037-1042
19. Sakiyama, T., Kohno, T., Mimaki, S., Ohta, T., Yanagitani, N., Sobue, T., Kunitoh, H., Saito, R., Shimizu, K., Hirama, C., Kimura, J., Maeno, G., Hirose, H., Eguchi, T., Saito, D., Ohki, M., and Yokota, J. (2005) Int. J. Cancer 114, 730-737
20. Boldrini, L., Gisfredi, S., Ursino, S., Lucchi, M., Greco, G., Mussi, A., and Fontanini, G. (2008) Oncol. Rep. 19, 771-773
21. Tommiska, J., Eerola, H., Heinonen, M., Salonen, L., Kaare, M., Tallila, J., Ristimäki, A., von Smitten, K., Aittomäki, K., Heikkilä, P., Blomqvist, C., and Nevanlinna, H. (2005) Clin. Cancer Res. 11, 5098-5103
22. Ohki, R., Kawase, T., Ohta, T., Ichikawa, H., and Taya, Y. (2007) Cancer Sci. 98, 189-200
23. Okamoto, K., Kashima, K., Pereg, Y., Ishida, M., Yamazaki, S., Nota, A., Teunisse, A., Migliorini, D., Kitabayashi, I., Marine, J. C., Prives, C., Shiloh, Y., Jochemsen, A. G., and Taya, Y. (2005) Mol. Cell. Biol. 25, 9608-9620
24. Shibata, T., Uryu, S., Kokubu, A., Hosoda, F., Ohki, M., Sakiyama, T., Matsuno, Y., Tsuchiya, R., Kanai, Y., Kondo, T., Imoto, I., Inazawa, J., and Hirohashi, S. (2005) Clin. Cancer Res. 11, 6177-6185
25. Cordenonsi, M., Montagner, M., Adorno, M., Zacchigna, L., Martello, G., Mamidi, A., Soligo, S., Dupont, S., and Piccolo, S. (2007) Science 315, 840-843
26. Phang, B. H., and Sabapathy, K. (2007) Oncogene 26, 2964-2974
27. Su, L., Sai, Y., Fan, R., Thurston, S. W., Miller, D. P., Zhou, W., Wain, J. C., Lynch, T. J., Liu, G., and Christiani, D. C. (2003) Lung Cancer 40, 259-266
28. Cordenonsi, M., Dupont, S., Maretto, S., Insinga, A., Imbriano, C., and Piccolo, S. (2003) Cell 113, 301-314