Metabolomic analysis of complex Chinese remedies: Examples of induced nephrotoxicity in the mouse from a series of remedies containing aristolochic acid

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Tsai, Dong Ming ^a   Kang, Jaw Jou ^b   Lee, Shoei Sheng ^b   Wang, San Yuan ^a   Tsai, I Lin ^a,b   Chen, Guan Yuan ^a,b   Liao, Hsiao Wei ^b   Wei Chu, Li ^c   Kuo, Ching Hua ^a,b   Tseng, Y Jane ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c Sheng Chang Pharmaceutical Co Ltd   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ARISTOLOCHIC ACID; BU FEI A JIAO TANG; CHINESE DRUG; MADOULING; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; HISTOPATHOLOGY; KIDNEY TUBULE DAMAGE; MALE; METABOLITE; METABOLOMICS; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84877263064     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/263757     Document Type: Article

References (46)

1. Mengs U., Acute toxicity of aristolochic acid in rodents. Archives of Toxicology 1987 59 5 328 331 2-s2.0-0022905438
2. Debelle F. D., Vanherweghem J. L., Nortier J. L., Aristolochic acid nephropathy: a worldwide problem. Kidney International 2008 74 2 158 169 2-s2.0-41549102309 10.1038/ki.2008.129 (Pubitemid 351915079)
3. Hashimoto K., Higuchi M., Makino B., Sakakibara I., Kubo M., Komatsu Y., Maruno M., Minoru Okada, Quantitative analysis of aristolochic acids, toxic compounds, contained in some medicinal plants. Journal of Ethnopharmacology 1999 64 2 185 189 2-s2.0-0033033959 10.1016/S0378-8741(98)00123-8 (Pubitemid 29130101)
4. Cheung T., Xue C., Leung K., Chan K., Li C., Aristolochic acids detected in some raw Chinese medicinal herbs and manufactured herbal products-a consequence of inappropriate nomenclature and imprecise labelling? Clinical Toxicology 2006 44 4 371 378 2-s2.0-33745685590 10.1080/15563650600671712 (Pubitemid 43995176)
5. Arlt V. M., Stiborova M., Schmeiser H. H., Aristolochic acid as a probable human cancer hazard in herbal remedies: a review. Mutagenesis 2002 17 4 265 277 2-s2.0-0036020624 (Pubitemid 34814645)
6. Heinrich M., Chan J., Wanke S., Neinhuis C., Simmonds M. S. J., Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2-A global assessment based on bibliographic sources. Journal of Ethnopharmacology 2009 125 1 108 144 2-s2.0-67749109772 10.1016/j.jep.2009.05. 028
7. Vanherweghem J. L., Depierreux M., Tielemans C., Abramowicz D., Dratwa M., Jadoul M., Richard C., Vandervelde D., Verbeelen D., Vanhaelen-Fastre R., Vanhaelen M., Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs. The Lancet 1993 341 8842 387 391 2-s2.0-0027512619 10.1016/0140-6736(93)92984-2 (Pubitemid 23048140)
8. Vanherweghem J. L., Debelle F., Muniz-Martinez M. C., Nortier J., Aristolochic acid nephropathy after Chinese herbal remedies. Clinical Nephrotoxins 2004 2nd New York, NY, USA Kluwer Academic 579 586
9. Nortier J. L., Martinez M. C. M., Schmeiser H. H., Arlt V. M., Bieler C. A., Petein M., Depierreux M. F., De Pauw L., Abramowicz D., Vereerstraeten P., Vanherweghem J. L., Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). The New England Journal of Medicine 2000 342 23 1686 1692 2-s2.0-0034622082 10.1056/NEJM200006083422301 (Pubitemid 30354515)
10. Gillerot G., Jadoul M., Arlt V. M., van Ypersele De Strihou C., Schmeiser H. H., But P. P., Bieler C. A., Cosyns J. P., Aristolochic acid nephropathy in a Chinese patient: time to abandon the term "Chinese herbs nephropathy"? American Journal of Kidney Diseases 2001 38 5 E26 2-s2.0-0035514681
11. Nortier J. L., Vanherweghem J. L., For patients taking herbal therapy-lessons from aristolochic acid nephropathy. Nephrology Dialysis Transplantation 2007 22 6 1512 1517 2-s2.0-34447566285 10.1093/ndt/gfm167 (Pubitemid 47073747)
12. Martena M. J., Van Der Wielen J. C. A., Van De Laak L. F. J., Konings E. J. M., De Groot H. N., Rietjens I. M. C. M., Enforcement of the ban on aristolochic acids in Chinese traditional herbal preparations on the Dutch market. Analytical and Bioanalytical Chemistry 2007 389 1 263 275 2-s2.0-34548282054 10.1007/s00216-007-1310-3 (Pubitemid 47325230)
13. Liu X. J., Su S. B., Study of combination methods for formula composition of Chinese herbal medicines and their components Journal of Chinese Integrative Medicine 2009 7 7 601 606 2-s2.0-73849114494 10.3736/jcim20090701
14. Qiu J., Traditional medicine: a culture in the balance. Nature 2007 448 7150 126 128 2-s2.0-34447512705 10.1038/448126a (Pubitemid 47067352)
15. Liu M., Gao Y., Xiao R., Zhang B. L., Fuzzy mathematic quantitative law of composing principle in the study of traditional Chinese medicine Yaoxue Xuebao 2009 44 1 38 41 2-s2.0-62749156839
16. Schaneberg B. T., Khan I. A., Analysis of products suspected of containing Aristolochia or Asarum species. Journal of Ethnopharmacology 2004 94 2-3 245 249 2-s2.0-4344624989 10.1016/j.jep.2004.06.010 (Pubitemid 39119925)
17. Laing C., Hamour S., Sheaff M., Miller R., Woolfson R., Chinese herbal uropathy and nephropathy. The Lancet 2006 368 9532 338 2-s2.0-33745997738 10.1016/S0140-6736(06)69079-X (Pubitemid 44067250)
18. Zhang N., Xie M., The nephrotoxicity in rats caused by Longdan Xiegan decoction. Zhongguo Zhongyao Zazhi 2006 31 10 836 839 2-s2.0-33846311432
19. Liu C., Tseng A., Yang S., Chinese Herbal Medicine: Modern Applications of Traditional Formulas 2005 Boca Raton, Fla, USA CRC Press
20. Nicholson J. K., Lindon J. C., Holmes E., 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999 29 11 1181 1189 2-s2.0-0032694577
21. Fiehn O., Metabolomics-the link between genotypes and phenotypes. Plant Molecular Biology 2002 48 1-2 155 171 2-s2.0-0036007687 10.1023/A:1013713905833 (Pubitemid 34128498)
22. Gowda G. A. N., Zhang S., Gu H., Asiago V., Shanaiah N., Raftery D., Metabolomics-based methods for early disease diagnostics. Expert Review of Molecular Diagnostics 2008 8 5 617 633 2-s2.0-52049108458 10.1586/14737159.8.5. 617
23. Mayr M., Metabolomics: ready for the prime time? Circulation 2008 1 1 58 65 2-s2.0-67650709732
24. Beger R. D., Sun J., Schnackenberg L. K., Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity. Toxicology and Applied Pharmacology 2010 243 2 154 166 2-s2.0-77949417518 10.1016/j.taap.2009.11.019
25. Zhang X., Wu H., Liao P., Li X., Ni J., Pei F., NMR-based metabonomic study on the subacute toxicity of aristolochic acid in rats. Food and Chemical Toxicology 2006 44 7 1006 1014 2-s2.0-33744947281 10.1016/j.fct.2005.12.004 (Pubitemid 43850068)
26. Liang Q., Ni C., Xie M., Zhang Q., Zhang Y. X., Yan X. Z., Yang M. J., Peng S. Q., Zhang Y. Z., Nephrotoxicity study of Aristolochia fangchi in rats by metabonomics Journal of Chinese Integrative Medicine 2009 7 8 746 752 2-s2.0-73449114246 10.3736/jcim20090808
27. Chen M., Su M., Zhao L., Jiang J., Liu P., Cheng J., Lai Y., Liu Y., Jia W., Metabonomic study of aristolochic acid-induced nephrotoxicity in rats. Journal of Proteome Research 2006 5 4 995 1002 2-s2.0-33645790992 10.1021/pr050404w
28. Coen M., Holmes E., Lindon J. C., Nicholson J. K., NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chemical Research in Toxicology 2008 21 1 9 27 2-s2.0-38949209075 10.1021/tx700335d (Pubitemid 351219705)
29. Shackelford C., Long G., Wolf J., Okerberg C., Herbert R., Qualitative and quantitative analysis of nonneoplastic lesions in toxicology studies. Toxicologic Pathology 2002 30 1 93 96 2-s2.0-0036186057 10.1080/ 01926230252824761 (Pubitemid 34194564)
30. R Development Core Team, R: A Language and Environment for Statistical Computing 2010 Vienna, Austria R Development Core Team
31. 1H NMR metabonomics. Analytical Chemistry 2006 78 13 4281 4290 2-s2.0-33745728718 10.1021/ac051632c
32. Indahl U. G., Martens H., Næs T., From dummy regression to prior probabilities in PLS-DA. Journal of Chemometrics 2007 21 12 529 536 2-s2.0-38949089692 10.1002/cem.1061
33. Mevik B. H., Wehrens R., The pls package: principal component and partial least squares regression in R. Journal of Statistical Software 2007 18 2 1 23 2-s2.0-33846829987
34. Westerhuis J. A., van Velzen E. J. J., Hoefsloot H. C. J., Smilde A. K., Discriminant Q2 (DQ2) for improved discrimination in PLSDA models. Metabolomics 2008 4 4 293 296 2-s2.0-55349093570 10.1007/s11306-008-0126-2
35. Lundstedt T., Seifert E., Abramo L., Thelin B., Nyström Å., Pettersen J., Bergman R., Experimental design and optimization. Chemometrics and Intelligent Laboratory Systems 1998 42 1-2 3 40 2-s2.0-0032563561 10.1016/S0169-7439(98)00065-3 (Pubitemid 28440359)
36. Wishart D. S., Tzur D., Knox C., Eisner R., Guo A. C., Young N., Cheng D., Jewell K., Arndt D., Sawhney S., Fung C., Nikolai L., Lewis M., Coutouly M. A., Forsythe I., Tang P., Shrivastava S., Jeroncic K., Stothard P., Amegbey G., Block D., Hau D. D., Wagner J., Miniaci J., Clements M., Gebremedhin M., Guo N., Zhang Y., Duggan G. E., MacInnis G. D., Weljie A. M., Dowlatabadi R., Bamforth F., Clive D., Greiner R., Li L., Marrie T., Sykes B. D., Vogel H. J., Querengesser L., HMDB: the human metabolome database. Nucleic Acids Research 2007 35 1 D521 D526 2-s2.0-33846088138 10.1093/nar/gkl923 (Pubitemid 46056263)
37. Bollard M. E., Keun H. C., Beckonert O., Ebbels T. M. D., Antti H., Nicholls A. W., Shockcor J. P., Cantor G. H., Stevens G., Lindon J. C., Holmes E., Nicholson J. K., Comparative metabonomics of differential hydrazine toxicity in the rat and mouse. Toxicology and Applied Pharmacology 2005 204 2 135 151 2-s2.0-20144388102 10.1016/j.taap.2004.06.031 (Pubitemid 40432371)
38. Martin F. P. J., Dumas M. E., Wang Y., Legido-Quigley C., Yap I. K. S., Tang H., Zirah S., Murphy G. M., Cloarec O., Lindon J. C., Sprenger N., Fay L. B., Kochhar S., Van Bladeren P., Holmes E., Nicholson J. K., A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. Molecular Systems Biology 2007 3 112 2-s2.0-34249036137 10.1038/msb4100153 (Pubitemid 46801777)
39. Sato N., Takahashi D., Chen S. M., Tsuchiya R., Mukoyama T., Yamagata S. I., Ogawa M., Yoshida M., Kondo S., Satoh N., Ueda S., Acute nephrotoxicity of aristolochic acids in mice. Journal of Pharmacy and Pharmacology 2004 56 2 221 229 2-s2.0-10744223031 10.1211/0022357023051 (Pubitemid 38232752)
40. Xue X., Xiao Y., Zhu H., Wang H., Liu Y., Xie T., Ren J., Induction of P450 1A by 3-methylcholanthrene protects mice from aristolochic acid-I-induced acute renal injury. Nephrology Dialysis Transplantation 2008 23 10 3074 3081 2-s2.0-52449095327 10.1093/ndt/gfn262
41. Shibutani S., Dong H., Suzuki N., Ueda S., Miller F., Grollman A. P., Selective toxicity of aristolochic acids I and II. Drug Metabolism and Disposition 2007 35 7 1217 1222 2-s2.0-34250785643 10.1124/dmd.107.014688 (Pubitemid 46956445)
42. Lenz E. M., Bright J., Knight R., Westwood F. R., Davies D., Major H., Wilson I. D., Metabonomics with 1H-NMR spectroscopy and liquid chromatography-mass spectrometry applied to the investigation of metabolic changes caused by gentamicin-induced nephrotoxicity in the rat. Biomarkers 2005 10 2-3 173 187 2-s2.0-21444445989 10.1080/13547500500094034 (Pubitemid 40916674)
43. Sieber M., Hoffmann D., Adler M., Vaidya V. S., Clement M., Bonventre J. V., Zidek N., Rached E., Amberg A., Callanan J. J., Dekant W., Mally A., Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity. Toxicological Sciences 2009 109 2 336 349 2-s2.0-66149143905 10.1093/toxsci/kfp070
44. Gartland K. P. R., Bonner F. W., Nicholson J. K., Investigations into the biochemical effects of region-specific nephrotoxins. Molecular Pharmacology 1989 35 2 242 250 2-s2.0-0024580448 (Pubitemid 19069600)
45. Holmes E., Bonner F. W., Nicholson J. K., Comparative studies on the nephrotoxicity of 2-bromoethanamine hydrobromide in the Fischer 344 rat and the multimammate desert mouse (Mastomys natalensis). Archives of Toxicology 1995 70 2 89 95 2-s2.0-0029565805 (Pubitemid 26008903)
46. Kandutsch A. A., Russell A. E., Creatine and creatinine in tissues and urine of mice with hereditary muscular dystrophy. The American Journal of Physiology 1958 194 3 553 556 2-s2.0-70449207225