Potential risk of mulberry-drug interaction: Modulation on P-glycoprotein and cytochrome P450 3A

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 18, 2013, Pages 4464-4469

  Hsu, Pei Wen ^a   Shia, Chi Sheng ^a   Lin, Shiuan Pey ^a   Chao, Pei Dawn Lee ^a   Juang, Shin Hun ^a,b   Hou, Yu Chi ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Cyclosporine; cytochrome P450 3A; mulberry; P glycoprotein

Indexed keywords

AREA UNDER THE CURVES; BLOOD CONCENTRATIONS; CYCLOSPORINE; CYTOCHROME P450; MECHANISM STUDIES; MULBERRY; P-GLYCOPROTEIN; THERAPEUTIC RANGE;

BIOCHEMISTRY; DRUG INTERACTIONS; FLAVONOIDS; GLYCOPROTEINS; RATS;

PLANTS (BOTANY);

CYCLOSPORIN; CYTOCHROME P450 3A; IMMUNOSUPPRESSIVE AGENT; MULTIDRUG RESISTANCE PROTEIN; POLYPHENOL;

ANIMAL; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; FRUIT; GENETICS; HERB DRUG INTERACTION; HUMAN; MALE; METABOLISM; MORUS; ORAL DRUG ADMINISTRATION; RAT; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOSPORINE; CYTOCHROME P-450 CYP3A; DOSE-RESPONSE RELATIONSHIP, DRUG; FRUIT; HERB-DRUG INTERACTIONS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; MORUS; P-GLYCOPROTEIN; POLYPHENOLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84877259699     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf3052384     Document Type: Article

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