메뉴 건너뛰기




Volumn 17, Issue 1, 2005, Pages 86-95

Inhibition of P-glycoprotein function and expression by kaempferol and quercetin

Author keywords

Flavonoids; Kaempferol; KB V1 cells; Multidrug resistance; P glycoprotein; Paclitaxel; Rhodamine123; Vinblastine

Indexed keywords

DAIDZEIN; DOXORUBICIN; FLAVONOL DERIVATIVE; GENISTEIN; GENISTIN; GLYCOPROTEIN P INHIBITOR; ISOFLAVONE DERIVATIVE; KAEMPFEROL; PACLITAXEL; QUERCETIN; TRITIUM; VINBLASTINE;

EID: 16244371036     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2005.17.1.86     Document Type: Article
Times cited : (188)

References (37)
  • 1
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • Endicott JA, Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu Rev Biochem 1989; 58:137-171.
    • (1989) Annu Rev Biochem , vol.58 , pp. 137-171
    • Endicott, J.A.1    Ling, V.2
  • 2
    • 0024279163 scopus 로고
    • The multidrug transporter, a double-edged sword
    • Gottesman MM, Pastan I. The multidrug transporter, a double-edged sword. J Biol Chem 1988; 263(25):12163-12166.
    • (1988) J Biol Chem , vol.263 , Issue.25 , pp. 12163-12166
    • Gottesman, M.M.1    Pastan, I.2
  • 3
    • 0026051296 scopus 로고
    • P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil
    • Miller TP, Grogan TM, Dalton WS, Spier CM, Scheper RJ, Salmon SE. P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil. J Clin Oncol 1991; 9(1):17-24.
    • (1991) J Clin Oncol , vol.9 , Issue.1 , pp. 17-24
    • Miller, T.P.1    Grogan, T.M.2    Dalton, W.S.3    Spier, C.M.4    Scheper, R.J.5    Salmon, S.E.6
  • 4
    • 0027136660 scopus 로고
    • Clinical trials of agents that reverse multidrug resistance. A literature review
    • Raderer M, Scheithauer W. Clinical trials of agents that reverse multidrug resistance. A literature review. Cancer 1993; 72(12):3553-3563.
    • (1993) Cancer , vol.72 , Issue.12 , pp. 3553-3563
    • Raderer, M.1    Scheithauer, W.2
  • 5
    • 0036774226 scopus 로고    scopus 로고
    • Flavonoid antioxidants: Chemistry, metabolism and structure-activity relationships
    • Heim KE, Tagliaferro AR, Bobilya DJ. Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships. J Nutr Biochem 2002; 13(10):572-584.
    • (2002) J Nutr Biochem , vol.13 , Issue.10 , pp. 572-584
    • Heim, K.E.1    Tagliaferro, A.R.2    Bobilya, D.J.3
  • 6
    • 0027132062 scopus 로고
    • Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells
    • Phang JM, Poore CM, Lopaczynska J, Yeh GC. Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells. Cancer Res 1993; 53(24):5977-5981.
    • (1993) Cancer Res , vol.53 , Issue.24 , pp. 5977-5981
    • Phang, J.M.1    Poore, C.M.2    Lopaczynska, J.3    Yeh, G.C.4
  • 7
    • 0028172728 scopus 로고
    • Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism
    • Critchfield JW, Welsh CJ, Phang JM, Yeh GC. Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism. Biochem Pharmacol 1994; 48(7):1437-1445.
    • (1994) Biochem Pharmacol , vol.48 , Issue.7 , pp. 1437-1445
    • Critchfield, J.W.1    Welsh, C.J.2    Phang, J.M.3    Yeh, G.C.4
  • 8
    • 0027981909 scopus 로고
    • Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target
    • Scambia G, Ranelletti FO, Panici PB et al. Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. Cancer Chemother Pharmacol 1994; 34(6):459-464.
    • (1994) Cancer Chemother Pharmacol , vol.34 , Issue.6 , pp. 459-464
    • Scambia, G.1    Ranelletti, F.O.2    Panici, P.B.3
  • 9
    • 0031581819 scopus 로고    scopus 로고
    • Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein
    • Shapiro AB, Ling V. Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein. Biochem Pharmacol 1997; 53(4):587-596.
    • (1997) Biochem Pharmacol , vol.53 , Issue.4 , pp. 587-596
    • Shapiro, A.B.1    Ling, V.2
  • 10
    • 0027482403 scopus 로고
    • Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells
    • Versantvoort CH, Schuurhuis GJ, Pinedo HM et al. Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells. Br J Cancer 1993; 68(5):939-946.
    • (1993) Br J Cancer , vol.68 , Issue.5 , pp. 939-946
    • Versantvoort, C.H.1    Schuurhuis, G.J.2    Pinedo, H.M.3
  • 11
    • 0031060647 scopus 로고    scopus 로고
    • Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein
    • Castro AF, Altenberg GA. Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. Biochem Pharmacol 1997; 53(1):89-93.
    • (1997) Biochem Pharmacol , vol.53 , Issue.1 , pp. 89-93
    • Castro, A.F.1    Altenberg, G.A.2
  • 12
    • 0034600237 scopus 로고    scopus 로고
    • Effect of bioflavonoids on vincristine transport across blood-brain barrier
    • Mitsunaga Y, Takanaga H, Matsuo H et al. Effect of bioflavonoids on vincristine transport across blood-brain barrier. Eur J Pharmacol 2000; 395(3):193-201.
    • (2000) Eur J Pharmacol , vol.395 , Issue.3 , pp. 193-201
    • Mitsunaga, Y.1    Takanaga, H.2    Matsuo, H.3
  • 13
    • 0023030685 scopus 로고
    • Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins
    • Shen DW, Cardarelli C, Hwang J et al. Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins. J Biol Chem 1986; 261(17):7762-7770.
    • (1986) J Biol Chem , vol.261 , Issue.17 , pp. 7762-7770
    • Shen, D.W.1    Cardarelli, C.2    Hwang, J.3
  • 14
    • 0026662530 scopus 로고
    • Partial purification and reconstitution of the human multidrug-resistance pump: Characterization of the drug-stimulatable ATP hydrolysis
    • Ambudkar SV, Lelong IH, Zhang J, Cardarelli CO, Gottesman MM, Pastan I. Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis. Proc Natl Acad Sci USA 1992; 89(18);8472-8476.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.18 , pp. 8472-8476
    • Ambudkar, S.V.1    Lelong, I.H.2    Zhang, J.3    Cardarelli, C.O.4    Gottesman, M.M.5    Pastan, I.6
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Meth 1983; 65(1-2):55-63.
    • (1983) J Immunol Meth , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 16
    • 0034487591 scopus 로고    scopus 로고
    • Comparison of in vitro growth-inhibitory activity of carboplatin and cisplatin on leukemic cells and hematopoietic progenitors: The myelosuppressive activity of carboplatin may be greater than its antileukemic effect
    • Su WC, Chang SL, Chen TY, Chen JS, Tsao CJ. Comparison of in vitro growth-inhibitory activity of carboplatin and cisplatin on leukemic cells and hematopoietic progenitors: the myelosuppressive activity of carboplatin may be greater than its antileukemic effect. Jpn J Clin Oncol 2000; 30(12):562-567.
    • (2000) Jpn J Clin Oncol , vol.30 , Issue.12 , pp. 562-567
    • Su, W.C.1    Chang, S.L.2    Chen, T.Y.3    Chen, J.S.4    Tsao, C.J.5
  • 17
    • 16244364509 scopus 로고    scopus 로고
    • Screening of flavonoids for their potential inhibitory effect on p-glycoprotein activity in human cervical carcinoma cells
    • Khantamat O, Chaiwangyen W, Limtrakul P. Screening of flavonoids for their potential inhibitory effect on p-glycoprotein activity in human cervical carcinoma cells. Chiang Mai Med Bull 2004; 43(2):45-56.
    • (2004) Chiang Mai Med Bull , vol.43 , Issue.2 , pp. 45-56
    • Khantamat, O.1    Chaiwangyen, W.2    Limtrakul, P.3
  • 18
    • 0027853682 scopus 로고
    • Differential modulation of P-glycoprotein transport by protein kinase inhibition
    • Bates SE, Lee JS, Dickstein B, Spolyar M, Fojo AT. Differential modulation of P-glycoprotein transport by protein kinase inhibition. Biochemistry 1993; 32(35):9156-9164.
    • (1993) Biochemistry , vol.32 , Issue.35 , pp. 9156-9164
    • Bates, S.E.1    Lee, J.S.2    Dickstein, B.3    Spolyar, M.4    Fojo, A.T.5
  • 19
    • 0032828093 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein activity and reversal of multidrug resistance in vitro by rosemary extract
    • Plouzek CA, Ciolino HP, Clarke R, Yeh GC. Inhibition of P-glycoprotein activity and reversal of multidrug resistance in vitro by rosemary extract. Eur J Cancer 1999; 35(10):1541-1545.
    • (1999) Eur J Cancer , vol.35 , Issue.10 , pp. 1541-1545
    • Plouzek, C.A.1    Ciolino, H.P.2    Clarke, R.3    Yeh, G.C.4
  • 20
    • 0029328438 scopus 로고
    • Epidemiological characteristics of prostate cancer in Gunma Prefecture, Japan
    • Gunma University Urological Oncology Study Group
    • Nakata S, Sato J, Imai K, Yamanaka H, Ichinose Y. Epidemiological characteristics of prostate cancer in Gunma Prefecture, Japan. Gunma University Urological Oncology Study Group. Int J Urol 1995; 2(3):191-197.
    • (1995) Int J Urol , vol.2 , Issue.3 , pp. 191-197
    • Nakata, S.1    Sato, J.2    Imai, K.3    Yamanaka, H.4    Ichinose, Y.5
  • 21
    • 0037103569 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells
    • Anuchapreeda S, Leechanachai P, Smith MM, Ambudkar SV, Limtrakul PN. Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells. Biochem Pharmacol 2002; 64(4):573-582.
    • (2002) Biochem Pharmacol , vol.64 , Issue.4 , pp. 573-582
    • Anuchapreeda, S.1    Leechanachai, P.2    Smith, M.M.3    Ambudkar, S.V.4    Limtrakul, P.N.5
  • 23
    • 0028128223 scopus 로고
    • Detection of soluble P-glycoprotein in culture media and extracellular fluid
    • Chu TM, Lin TH, Kawinski E. Detection of soluble P-glycoprotein in culture media and extracellular fluid. Biochem Biophys Res Commun 1994; 203:506-512.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 506-512
    • Chu, T.M.1    Lin, T.H.2    Kawinski, E.3
  • 24
    • 0029922333 scopus 로고    scopus 로고
    • Relation among the resistance factor, kinetics of uptake, and kinetics of the P-glycoprotein-mediated efflux of doxorubicin, daunorubicin, 8-(S)-fluoroidarubicin, and idarubicin in multidrug-resistant K562 cells
    • Mankhetkom S, Dubru F. Hesschenbrouck J, Fiallo M, Garnier-Suillerot A. Relation among the resistance factor, kinetics of uptake, and kinetics of the P-glycoprotein-mediated efflux of doxorubicin, daunorubicin, 8-(S)-fluoroidarubicin, and idarubicin in multidrug-resistant K562 cells. Mol Pharmacol 1996; 49(3):532-539.
    • (1996) Mol Pharmacol , vol.49 , Issue.3 , pp. 532-539
    • Mankhetkom, S.1    Dubru, F.2    Hesschenbrouck, J.3    Fiallo, M.4    Garnier-Suillerot, A.5
  • 25
    • 3042836363 scopus 로고    scopus 로고
    • Modulation of human multidrug- resistance MDR-1 gene by natural curcuminoids
    • Limtrakul P, Anuchapreeda S, Bhudsuk D. Modulation of human multidrug- resistance MDR-1 gene by natural curcuminoids. BMC Cancer 2004; 4(1):13-21.
    • (2004) BMC Cancer , vol.4 , Issue.1 , pp. 13-21
    • Limtrakul, P.1    Anuchapreeda, S.2    Bhudsuk, D.3
  • 26
    • 0022457103 scopus 로고
    • Human multidrug-resistant cell lines: Increased mdr1 expression can precede gene amplification
    • Shen DW, Fojo A, Chin JE et al. Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification. Science 1986; 232(4750):643-645.
    • (1986) Science , vol.232 , Issue.4750 , pp. 643-645
    • Shen, D.W.1    Fojo, A.2    Chin, J.E.3
  • 27
    • 0026598039 scopus 로고
    • Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1)
    • Kioka N, Yamano Y, Komano T, Ueda K. Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1). FEBS Lett 1992; 301(1):37-40.
    • (1992) FEBS Lett , vol.301 , Issue.1 , pp. 37-40
    • Kioka, N.1    Yamano, Y.2    Komano, T.3    Ueda, K.4
  • 28
    • 0026807001 scopus 로고
    • Activation of human multidrug resistance-1 gene promoter in response to heat shock stress
    • Miyazaki M, Kohno K, Uchiumi T et al. Activation of human multidrug resistance-1 gene promoter in response to heat shock stress. Biochem Biophys Res Commun 1992; 187(2):677-684.
    • (1992) Biochem Biophys Res Commun , vol.187 , Issue.2 , pp. 677-684
    • Miyazaki, M.1    Kohno, K.2    Uchiumi, T.3
  • 29
    • 0032581075 scopus 로고    scopus 로고
    • Suppression of multidrug resistance via inhibition of heat shock factor by quercetin in MDR cells
    • Kim SH, Yeo GS, Lim YS, Kang CD, Kim CM, Chung BS. Suppression of multidrug resistance via inhibition of heat shock factor by quercetin in MDR cells. Exp Mol Med 1998; 30(2):87-92.
    • (1998) Exp Mol Med , vol.30 , Issue.2 , pp. 87-92
    • Kim, S.H.1    Yeo, G.S.2    Lim, Y.S.3    Kang, C.D.4    Kim, C.M.5    Chung, B.S.6
  • 30
    • 0028807793 scopus 로고
    • Effects of flavonols on P-glycoprotein activity in cultured rat hepatocytes
    • Chieli E, Romiti N, Cervelli F, Tongiani R. Effects of flavonols on P-glycoprotein activity in cultured rat hepatocytes. Life Sci 1995; 57(19):1741-1751.
    • (1995) Life Sci , vol.57 , Issue.19 , pp. 1741-1751
    • Chieli, E.1    Romiti, N.2    Cervelli, F.3    Tongiani, R.4
  • 31
    • 0030390492 scopus 로고    scopus 로고
    • Resistance mechanisms and their regulation in lung cancer
    • Volm K, Mattern J. Resistance mechanisms and their regulation in lung cancer. Crit Rev Oncogen 1996; 7: 227-244.
    • (1996) Crit Rev Oncogen , vol.7 , pp. 227-244
    • Volm, K.1    Mattern, J.2
  • 32
    • 0026092106 scopus 로고
    • What's new in cytostatic drug resistance and pathology
    • Dietel M. What's new in cytostatic drug resistance and pathology. Pathol Res Pract 1991; 187(7):892-905.
    • (1991) Pathol Res Pract , vol.187 , Issue.7 , pp. 892-905
    • Dietel, M.1
  • 33
    • 0025562606 scopus 로고
    • Mechanisms of multidrug resistance in human tumor cells. The roles of P-glycoprotein, DNA topoisomerase II, and other factors
    • Beck WT. Mechanisms of multidrug resistance in human tumor cells. The roles of P-glycoprotein, DNA topoisomerase II, and other factors. Cancer Treat Rev 1990; 17 Suppl A:11-20.
    • (1990) Cancer Treat Rev , vol.17 , Issue.SUPPL. A , pp. 11-20
    • Beck, W.T.1
  • 34
    • 0025345059 scopus 로고
    • Glutathione S-transferases and drug resistance
    • Morrow CS, Cowan KH. Glutathione S-transferases and drug resistance. Cancer Cells 1990; 2(1):15-22.
    • (1990) Cancer Cells , vol.2 , Issue.1 , pp. 15-22
    • Morrow, C.S.1    Cowan, K.H.2
  • 35
    • 0024474716 scopus 로고
    • Enhanced efflux of [3H]vinblastine from Chinese hamster ovary cells transfected with a full-length complementary DNA clone for the mdr1 gene
    • Hammond JR, Johnstone RM, Gros P. Enhanced efflux of [3H]vinblastine from Chinese hamster ovary cells transfected with a full-length complementary DNA clone for the mdr1 gene. Cancer Res 1989; 49(14):3867-3871.
    • (1989) Cancer Res , vol.49 , Issue.14 , pp. 3867-3871
    • Hammond, J.R.1    Johnstone, R.M.2    Gros, P.3
  • 36
    • 0030999750 scopus 로고    scopus 로고
    • Apoptosis and the dilemma of cancer chemotherapy
    • Hannun YA. Apoptosis and the dilemma of cancer chemotherapy. Blood 1997; 89(6):1845-1853.
    • (1997) Blood , vol.89 , Issue.6 , pp. 1845-1853
    • Hannun, Y.A.1
  • 37
    • 0035079539 scopus 로고    scopus 로고
    • Ceramide glycosylation potentiates cellular multidrug resistance
    • Liu YY, Han TY, Giuliano AE, Cabot MC. Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J 2001; 15(3):719-730.
    • (2001) FASEB J , vol.15 , Issue.3 , pp. 719-730
    • Liu, Y.Y.1    Han, T.Y.2    Giuliano, A.E.3    Cabot, M.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.