SCL expression in the mouse embryo detected with a targeted lacZ reporter gene demonstrates its localization to hematopoietic, vascular, neural tissues

Blood

Volumn 94, Issue 11, 1999, Pages 3754-3763

  Elefanty, Andrew G ^a   Begley, C Glenn ^a   Hartley, Lynne ^a   Papaevangeliou, Bette ^a   Robb, Lorraine ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; GENE TARGETING; HEMATOPOIESIS; HETEROZYGOSITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REPORTER GENE; TISSUE DISTRIBUTION;

ESCHERICHIA COLI;

EID: 0033485333     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.11.3754     Document Type: Article

References (74)

1. Begley CG, Green AR: The SCL gene: From case report to critical hematopoietic regulator. Blood 93:2760, 1999
2. Robb L, Lyons I, Ruili L, Hartley L, Köntgen F, Harvey RP, Metcalf D, Begley CG: Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene. Proc Natl Acad Sci USA 92:7075, 1995
3. Shivdasani RA, Mayer EL, Orkin SH: Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature 373:432, 1995
4. Robb L, Elwood NJ, Elefanty AG, Köntgen F, Li R, Barnett LD, Begley CG: The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse. EMBO J 15:4123, 1996
5. Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt FW, Orkin SH: The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell 86:47, 1996
6. Elefanty AG, Robb L, Birner R, Begley CG: Hematopoietic-specific genes are not induced during in vitro differentiation of scl-null embryonic stem cells. Blood 90:1435, 1997
7. Visvader J, Begley CG, Adams JM: Differential expression of the LYL, SCL and E2A helix-loop-helix genes within the hemopoietic system. Oncogene 6:187, 1991
8. Green AR, Salvaris E, Begley CG: Erythroid expression of the 'helix-loop-helix' gene, SCL. Oncogene 6:475, 1991
9. Green AR, Lints T, Visvader J, Harvey R, Begley CG: SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain. Oncogene 7:653, 1992
10. Mouthon M-A, Bernard O, Mitjavila M-T, Romeo P-H, Vainchenker W, Mathieu-Mahul D: Expression of tal-1 and GATA binding proteins during human hematopoiesis. Blood 81:647, 1993
11. Cheng T, Shen H, Giokas D, Gere J, Tenen DG, Scadden DT: Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells. Proc Natl Acad Sci USA 93:13158, 1996
12. Miller BA, Floros J, Cheung JY, Wojchowski DM, Bell L, Begley CG, Elwood NJ, Kreider J, Christian C: Steel factor affects SCL expression during normal erythroid differentiation. Blood 84:2971, 1994
13. Tanigawa T, Nicola N, McArthur GA, Strasser A, Begley CG: Differential regulation of macrophage differentiation in response to leukemia inhibitory factor/oncostatin-M/interleukin-6: The effect of enforced expression of the SCL transcription factor. Blood 85:379, 1995
14. Hoang T, Paradis É, Brady G, Billia F, Nakahara K, Iscove NN, Kirsch IR: Opposing effects of the basic helix-loop-helix transcription factor SCL on erythroid and monocytic differentiation. Blood 87:102, 1996
15. Elwood NJ, Zogos H, Pereria D, Dick JE, Begley CG: Enhanced megakaryocyte and erythroid development from normal human CD34 positive cells: Consequences of enforced expression of SCL. Blood 91:3756, 1998
16. Valtieri M, Tocci A, Gabbianelli M, Luchetti L, Masella B, Vitelli L, Botta R, Testa U, Condorelli GL, Peschle C: Enforced TAL-1 expression stimulates primitive, erythroid and megakaryocytic progenitors but blocks the granulopoietic differentiation program. Cancer Res 58:562, 1998
17. Green A: Master regulator unmasked. Nature 383:575, 1996
18. Shivdasani RA, Orkin SH: The transcriptional control of hematopoiesis. Blood 87:4025, 1996
19. Wadman IA, Osada H, Grütz GG, Agulnick AD, Westphal H, Forster A, Rabbitts TH: The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins. EMBO J 16:3145, 1997
20. Warren AJ, Colledge WH, Carlton MBL, Evans MJ, Smith AJH, Rabbitts TH: The oncogenic cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development. Cell 78:45, 1994
21. Yamada Y, Warren AJ, Dobson C, Forster A, Pannell R, Rabbitts TH: The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis. Proc Natl Acad Sci USA 95:3890, 1998
22. Elefanty AG, Begley CG, Metcalf D, Barnett L, Köntgen F, Robb L: Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ 'knock-in' strategy. Proc Natl Acad Sci USA 95:11897, 1998
23. Schlaeger TM, Y. Q, Fujiwara Y, Magram J, Sato TN: Vascular endothelial cell lineage-specific promoter in transgenic mice. Development 121:1089, 1995
24. Fiering SN, Roederer M, Nolan GP, Micklem DR, Parks DR, Herzenberg LA: Improved FACS-Gal: Flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs. Cytometry 12:291, 1991
25. Metcalf D: Clonal Culture of Hemopoietic Cells: Techniques and Applications. Amsterdam, The Netherlands, Elsevier, 1984
26. Johnson GR, Barker DC: Erythroid progenitor cells and stimulating factors during murine embryonic and fetal development. Exp Hematol 13:200, 1985
27. Yamaguchi TP, Dumont DJ, Conlon RA, Breitman ML, Rossant J: flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial precursors. Development 118:489, 1993
28. Kallianpur AR, Jordan JE, Brandt SJ: The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood 83:1200, 1994
29. Silver L, Palis J: Initiation of murine embryonic erythropoiesis: A spatial analysis. Blood 89:1154, 1997
30. Albeda SM, Muller WA, Buck CA, Newman PJ: Molecular and cellular properties of PECAM-1(endoCAM/CD31): A novel vascular cell-cell adhesion molecule. J Cell Biol 114:1059, 1991
31. Visvader JE, Fujiwara Y, Orkin SH: Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development. Genes Dev 12:473, 1998
32. Garcia-Porrero JA, Manaia A, Jimeno J, Lasky LA, Dieterlen-Lièvre F, Godin IE: Antigenic profiles of endothelial and hemopoietic lineages in murine intraembryonic hemogenic sites. Dev Comp Immunol 22:303, 1998
33. Sinclair AM, Göttgens B, Barton LM, Stanley ML, Pardanaud L, Klaine M, Gering M, Bahn S, Sanchez M-J, Bench AJ, Fordham JL, Bockamp E-O, Green AR: Distinct 5′ SCL enhancers direct transcription to developing brain, spinal cord, and endothelium: Neural expression is mediated by GATA factor binding sites. Dev Biol 209:128, 1999
34. Mead PE, Kelley CM, Hahn PS, Piedad O, Zon LI: SCL specifies hematopoietic mesoderm in Xenopus embryos. Development 125:2611, 1998
35. Gering M, Rodaway AR, Gottgens B, Patient RK, Green AR: The SCL gene specifies haemangioblast development from early mesoderm. EMBO J 17:4029, 1998
36. Dieterlen-Lièvre F, Godin I, Pardanaud L: Where do hematopoietic stem cells come from? Int Arch Allergy Immunol 112:3, 1997
37. Garcia-Porrero JA, Godin IE, Dieterlen-Lièvre F: Potential intraembryonic hemogenic sites at pre-liver stages in the mouse. Anat Embryol 192:425, 1995
38. Hwang L-Y, Siegelman M, Davis L, Oppenheimer-Marks N, Baer R: Expression of the TAL1 proto-oncogene in cultured endothelial cells and blood vessels of the spleen. Oncogene 8:3043, 1993
39. Turpen JB, Kelley CM, Mead PE, Zon LI: Bipotential primitive-definitive hematopoietic progenitors in the vertebrate embryo. Immunity 7:325, 1997
40. Liao EC, Paw BH, Oates AC, Pratt SJ, Postlethwait JH, Zon LI: SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes Dev 12:621, 1998
41. Wong PMC, Chung SW, Chui DHK, Eaves CJ: Properties of the earliest clonogenic hemopoietic precursors to appear in the developing murine yolk sac. Proc Natl Acad Sci USA 83:3851, 1986
42. Onodera K, Takahashi S, Nishimura S, Ohta J, Motohashi H, Yomogida K, Hayashi N, Engel JD, Yamamoto M: GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis. Proc Natl Acad Sci USA 94:4487, 1997
43. Wood HB, May G, Healy L, Enver T, Morriss-Kay GM: CD34 expression patterns during early mouse development are related to modes of blood vessel formation and reveal additional sites of hematopoiesis. Blood 90:2300, 1997
44. + hematopoietic cells in the early human embryo. Blood 87:67, 1996
45. Tavian M, Hallais M-F, Péault B: Emergence of intraembryonic hematopoietic precursors in the pre-liver human embryo. Development 126:793, 1999
46. Labastie M-C, Cortés F, Roméo P-H, Dulac C, Péault B: Molecular identity of hematopoietic precursor cells emerging in the human embryo. Blood 92:3624, 1998
47. Jaffredo T, Gautier R, Eichmann A, Dieterlen-Lièvre F: Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny. Development 125:4575, 1998
48. lacZ mouse embryos. Development 122:3023, 1996
49. Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu X-F, Breitman ML, Schuh AC: Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376:62, 1995
50. Shalaby F, Ho J, Stanford WL, Fischer KD, Schuh AC, Schwartz L, Bernstein A, Rossant J: A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89:981, 1997
51. Noback CR, Demarest RJ: The Human Nervous System (ed 2). New York, NY, McGraw-Hil), 1975
52. Everling S, Dorris MC, Klein RM, Munoz DP: Role of primate superior colliculus in preparation and execution of anti-saccades and pro-saccades. J Neurosci 19:2740, 1999
53. Oosterwegel M, Timmerman J, Leiden J, Clevers H: Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis. Dev Immunol 3:1, 1992
54. George KG, Leonard MW, Roth ME, Lieuw KH, Kioussis D, Grosveld F, Engel JD: Embryonic expression and cloning of the murine GATA-3 gene. Development 120:2673, 1994
55. Kornhauser JM, Leonard MW, Yamamoto M, LaVail JH, Mayo KE, Engel JD: Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum. Mol Brain Res 23:100, 1994
56. Zhou Y, Lim K-C, Onodera K, Takahashi S, Ohta J, Minegishi N, Tsai F-Y, Orkin SH, Yamamoto M, Engel JD: Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development. EMBOJ 17:6689, 1998
57. Dickson MC, Martin JS, Cousins FM, Kulkarni AB, Karlsson S, Akhurst RJ: Defective haematopoiesis and vasculogenesis in transforming growth factor-β 1 knock out mice. Development 121:1845, 1995
58. Oshima M, Oshima H, Taketo MM: TGF-β receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev Biol 179:297, 1996
59. Lin Q, Lu J, Yanagisawa H, Webb R, Lyons GE, Richardson JA, Olson EN: Requirement of the MADS-box transcription factor MEF2C for vascular development. Development 125:4565, 1998
60. Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declerq C, Pawling J, Moons L, Collen D, Risau W, Nagy A: Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435, 1996
61. Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ, Moore MW: Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380:439, 1996
62. -1- embryonic stem cells and embryos. Proc Natl Acad Sci USA 96:2159, 1999
63. Maltepe E, Schmidt JV, Baunoch D, Bradfield CA, Simon MC: Abnormal angiogenesis and responses to glucose deprivation in mice lacking the protein ARNT. Nature 386:403, 1997
64. 2 homeostasis by hypoxia-inducible factor 1 a. Genes Dev 12:149, 1998
65. Ryan HE, Lo J, Johnson RS: HIF-1 a is required for solid tumor formation and embryonic vascularization. EMBO J 17:3005, 1998
66. Dumont DJ, Gradwohl G, Fong GH, Puri MC, Gertsenstein M, Auerbach R, Breitman ML: Dominant-negative and targeted null-mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis in the embryo. Genes Dev 8:1897, 1994
67. Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, Gendron-Maguire M, Gridley T, Wolburg H, Risau W, Qin Y: Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376:70, 1995
68. Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, Davis S, Sato TN, Yancopoulos GD: Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87:1171, 1996
69. Wang LC, Kuo F, Fujiwara Y, Gilliland DG, Golub TR, Orkin SH: Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL. EMBO J 16:4374, 1997
70. Dumont DJ, Jussila L, Taipale J, Lymboussaki A, Mustonen T, Pajusola K, Breitman M, Alitalo K: Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 282:946, 1998
71. Wang HU, Chen Z-F, Anderson DJ: Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93:741, 1998
72. Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U, Risau W, Klein R: Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev 13: 295, 1999
73. Pardanaud L, Luton D, Prigent M, Bourcheix L-M, Catala M, Dieterlen-Lièvre F: Two distinct endothelial lineages in ontogeny, one of them related to hemopoiesis. Development 122:1363, 1996
74. Pardanaud L, Dieterlen-Lièvre F: Manipulation of the angiopoietic/hemangiopoietic commitment in the avian embryo. Development 126:617, 1999