Optimization of tumor xenograft dissociation for the profiling of cell surface markers and nutrient transporters

Laboratory Investigation

Volumn 93, Issue 5, 2013, Pages 611-621

  Petit, Vincent ^a,b,e   Massonnet, Gérald ^c,e   MacIorowski, Zofia ^c   Touhami, Jawida ^a,b   Thuleau, Aurélie ^c   Némati, Fariba ^c   Laval, Julie ^a,b   Château Joubert, Sophie ^d   Servely, Jean Luc ^d   Vallerand, David ^c   Fontaine, Jean Jacques ^d   Taylor, Naomi ^a,b   Battini, Jean Luc ^a,b   Sitbon, Marc ^a,b   Decaudin, Didier ^c  

^a CNRS   (France)

^b UNIV MONTPELLIER   (France)

^c INSTITUT CURIE   (France)

^d UNIVERSITÉ PARIS EST   (France)

^e Cap Alpha   (France)

Author keywords

breast cancer; cell surface transportome; flow cytometry analysis; live cells; metabolite transporters; tumor dissociation; xenografts

Indexed keywords

CELL SURFACE MARKER; CELL SURFACE PROTEIN; GLUCOSE; GLUTAMINE; LIGAND; PHOSPHATE; PROTEIN ASCT2; PROTEIN GLUT1; PROTEIN PIT1; PROTEIN PIT2; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CELL; CELL METABOLISM; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROCEDURES; PROTEIN EXPRESSION; TUMOR DISSOCIATION; TUMOR XENOGRAFT;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD44; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; REPRODUCIBILITY OF RESULTS; TRANSPLANTATION, HETEROLOGOUS; TUMOR MARKERS, BIOLOGICAL;

EID: 84877248799     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2013.44     Document Type: Article

References (38)

1. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-674.
2. Hsu PP, Sabatini DM. Cancer cell metabolism: Warburg and beyond. Cell 2008;134:703-707.
3. Rubakhin SS, Romanova EV, Nemes P, et al. Profiling metabolites and peptides in single cells. Nat Methods 2011;8(Suppl):S20-S29.
4. Ganapathy V, Thangaraju M, Prasad PD. Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. Pharmacol Ther 2009;121:29-40.
5. Kinet S, Swainson L, Lavanya M, et al. Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4\+ and CD8\+ T cells. Retrovirology 2007;4:31.
6. Yonezawa A, Masuda S, Katsura T, et al. Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1. Am J Physiol Cell Physiol 2008;295:C632-C641.
7. Manel N, Battini JL, Taylor N, et al. HTLV-1 tropism and envelope receptor. Oncogene 2005;24:6016-6025.
8. Overbaugh J, Miller AD, Eiden MV. Receptors and entry cofactors for retroviruses include single and multiple transmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins. Microbiol Mol Biol Rev 2001;65:371-389.
9. Lagrue E, Abe H, Lavanya M, et al. Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport. J Biomed Sci 2010;17:91.
10. Loisel-Meyer S, Swainson L, Craveiro M, et al. Glut1-mediated glucose transport regulates HIV infection. Proc Natl Acad Sci USA 2012;109:2549-2554.
11. Manel N, Kim FJ, Kinet S, et al. The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Cell 2003;115:449-459.
12. Montel-Hagen A, Kinet S, Manel N, et al. Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C. Cell 2008;132:1039-1048.
13. Swainson L, Kinet S, Manel N, et al. Glucose transporter 1 expression identifies a population of cycling CD4\+ CD8\+ human thymocytes with high CXCR4-induced chemotaxis. Proc Natl Acad Sci USA 2005;102:12867-12872.
14. Decaudin D. Primary human tumor xenografted models ('tumorgrafts') for good management of patients with cancer. Anticancer Drugs 2011;22:827-841.
15. Derose YS, Wang G, Lin YC, et al. Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat Med 2011;17:1514-1520.
16. Garber K. From human to mouse and back: 'tumorgraft' models surge in popularity. J Natl Cancer Inst 2009;101:6-8.
17. Brockhoff G, Fleischmann S, Meier A, et al. Use of a mechanical dissociation device to improve standardization of flow cytometric cytokeratin DNA measurements of colon carcinomas. Cytometry 1999;38:184-191.
18. Corver WE, Cornelisse CJ, Hermans J, et al. Limited loss of nine tumorassociated surface antigenic determinants after tryptic cell dissociation. Cytometry 1995;19:267-272.
19. Haghighat N, McCandless DW, Geraminegad P. Responses in primary astrocytes and C6-glioma cells to ammonium chloride and dibutyryl cyclic-AMP. Neurochem Res 2000;25:277-284.
20. Davidson WF, Parish CR. A procedure for removing red cells and dead cells from lymphoid cell suspensions. J Immunol Methods 1975;7:291-300.
21. Rubenstein M, Anderson KM. Isolation of viable rat ventral prostate epithelial and nonepithelial cells. Endocrinology 1980;106:530-540.
22. Marangoni E, Vincent-Salomon A, Auger N, et al. A new model of patient tumor-derived breast cancer xenografts for preclinical assays. Clin Cancer Res 2007;13:3989-3998.
23. Workman P, Aboagye EO, Balkwill F, et al. Guidelines for the welfare and use of animals in cancer research. Br J Cancer 2010;102: 1555-1577.
24. Battini JL, Rasko JE, Miller AD. A human cell-surface receptor for xenotropic and polytropic murine leukemia viruses: possible role in G protein-coupled signal transduction. Proc Natl Acad Sci USA 1999;96:1385-1390.
25. Roederer M. Compensation in flow cytometry. Curr Protoc Cytom 2002;Chapter 1(Unit 1):14.
26. Irizarry RA, Bolstad BM, Collin F, et al. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 2003;31:e15.
27. Gotte M, Yip GW. Heparanase, hyaluronan, and CD44 in cancers: a breast carcinoma perspective. Cancer Res 2006;66:10233-10237.
28. Manel N, Battini JL, Sitbon M. Human T cell leukemia virus envelope binding and virus entry are mediated by distinct domains of the glucose transporter GLUT1. J Biol Chem 2005;280: 29025-29029.
29. Tailor CS, Nouri A, Zhao Y, et al. A sodium-dependent neutralamino-acid transporter mediates infections of feline and baboon endogenous retroviruses and simian type D retroviruses. J Virol 1999;73:4470-4474.
30. Oliveira NM, Farrell KB, Eiden MV. In vitro characterization of a koala retrovirus. J Virol 2006;80:3104-3107.
31. Kavanaugh MP, Miller DG, Zhang W, et al. Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters. Proc Natl Acad Sci USA 1994;91:7071-7075.
32. Hidalgo M, Bruckheimer E, Rajeshkumar NV, et al. A pilot clinical study of treatment guided by personalized tumorgrafts in patients with advanced cancer. Mol Cancer Ther 2011;10:1311-1316.
33. Nicklin P, Bergman P, Zhang B, et al. Bidirectional transport of amino acids regulates mTOR and autophagy. Cell 2009;136:521-534.
34. Beck L, Leroy C, Salaun C, et al. Identification of a novel function of PiT1 critical for cell proliferation and independent from its phosphate transport activity. J Biol Chem 2009;284:31363-31374.
35. Barnes K, McIntosh E, Whetton AD, et al. Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation. Oncogene 2005;24:3257-3267.
36. Todorova VK, Kaufmann Y, Luo S, et al. Tamoxifen and raloxifene suppress the proliferation of estrogen receptor-negative cells through inhibition of glutamine uptake. Cancer Chemother Pharmacol 2011;67:285-291.
37. Ichinoe M, Mikami T, Yoshida T, et al. High expression of L-type aminoacid transporter 1 (LAT1) in gastric carcinomas: comparison with noncancerous lesions. Pathol Int 2011;61:281-289.
38. Lee YY, Choi CH, Do IG, et al. Prognostic value of the copper transporters, CTR1 and CTR2, in patients with ovarian carcinoma receiving platinum-based chemotherapy. Gynecol Oncol 2011;122: 361-365.