-
1
-
-
79959466181
-
Genomic and biochemical insights into the specificity of ETS transcription factors
-
Hollenhorst, P.C., McIntosh, L.P. and Graves, B.J. (2011) Genomic and biochemical insights into the specificity of ETS transcription factors. Annu. Rev. Biochem., 80, 437-471.
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 437-471
-
-
Hollenhorst, P.C.1
McIntosh, L.P.2
Graves, B.J.3
-
2
-
-
33746983022
-
The Ets transcription factors of the PEA3 group: Transcriptional regulators in metastasis
-
de Launoit, Y., Baert, J.L., Chotteau-Lelievre, A., Monte, D., Coutte, L., Mauen, S., Firlej, V., Degerny, C. and Verreman, K. (2006) The Ets transcription factors of the PEA3 group: transcriptional regulators in metastasis. Biochim. Biophys. Acta, 1766, 79-87.
-
(2006)
Biochim. Biophys. Acta
, vol.1766
, pp. 79-87
-
-
De Launoit, Y.1
Baert, J.L.2
Chotteau-Lelievre, A.3
Monte, D.4
Coutte, L.5
Mauen, S.6
Firlej, V.7
Degerny, C.8
Verreman, K.9
-
3
-
-
0030810059
-
The ETS family member ERM contains an alpha-helical acidic activation domain that contacts TAFII60
-
Defossez, P.A., Baert, J.L., Monnot, M. and de Launoit, Y. (1997) The ETS family member ERM contains an alpha-helical acidic activation domain that contacts TAFII60. Nucleic Acids Res., 25, 4455-4463.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4455-4463
-
-
Defossez, P.A.1
Baert, J.L.2
Monnot, M.3
De Launoit, Y.4
-
4
-
-
0029917990
-
Two functionally distinct domains responsible for transactivation by the Ets family member ERM
-
Laget, M.P., Defossez, P.A., Albagli, O., Baert, J.L., Dewitte, F., Stehelin, D. and de Launoit, Y. (1996) Two functionally distinct domains responsible for transactivation by the Ets family member ERM. Oncogene, 12, 1325-1336.
-
(1996)
Oncogene
, vol.12
, pp. 1325-1336
-
-
Laget, M.P.1
Defossez, P.A.2
Albagli, O.3
Baert, J.L.4
Dewitte, F.5
Stehelin, D.6
De Launoit, Y.7
-
5
-
-
40849085555
-
ERM transcription factor contains an inhibitory domain which functions in sumoylation-dependent manner
-
Degerny, C., de Launoit, Y. and Baert, J.L. (2008) ERM transcription factor contains an inhibitory domain which functions in sumoylation-dependent manner. Biochim. Biophys. Acta, 1779, 183-194.
-
(2008)
Biochim. Biophys. Acta
, vol.1779
, pp. 183-194
-
-
Degerny, C.1
De Launoit, Y.2
Baert, J.L.3
-
6
-
-
21644488841
-
SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity
-
Degerny, C., Monte, D., Beaudoin, C., Jaffray, E., Portois, L., Hay, R.T., de Launoit, Y. and Baert, J.L. (2005) SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity. J. Biol. Chem., 280, 24330-24338.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 24330-24338
-
-
Degerny, C.1
Monte, D.2
Beaudoin, C.3
Jaffray, E.4
Portois, L.5
Hay, R.T.6
De Launoit, Y.7
Baert, J.L.8
-
7
-
-
0035830899
-
The PEA3 Ets transcription factor comprises multiple domains that regulate transactivation and DNA binding
-
Bojovic, B.B. and Hassell, J.A. (2001) The PEA3 Ets transcription factor comprises multiple domains that regulate transactivation and DNA binding. J. Biol. Chem., 276, 4509-4521.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4509-4521
-
-
Bojovic, B.B.1
Hassell, J.A.2
-
8
-
-
0029926301
-
Analysis of the ERK-stimulated ETS transcription factor ER81
-
Janknecht, R. (1996) Analysis of the ERK-stimulated ETS transcription factor ER81. Mol. Cell Biol., 16, 1550-1156.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 1550-1156
-
-
Janknecht, R.1
-
9
-
-
77955561331
-
Solution structure of the N-terminal transactivation domain of ERM modified by SUMO-1
-
Lens, Z., Dewitte, F., Monte, D., Baert, J.L., Bompard, C., Senechal, M., Van Lint, C., de Launoit, Y., Villeret, V. and Verger, A. (2010) Solution structure of the N-terminal transactivation domain of ERM modified by SUMO-1. Biochem. Biophys. Res. Commun., 399, 104-110.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.399
, pp. 104-110
-
-
Lens, Z.1
Dewitte, F.2
Monte, D.3
Baert, J.L.4
Bompard, C.5
Senechal, M.6
Van Lint, C.7
De Launoit, Y.8
Villeret, V.9
Verger, A.10
-
10
-
-
0026086914
-
Critical structural elements of the VP16 transcriptional activation domain
-
Cress, W.D. and Triezenberg, S.J. (1991) Critical structural elements of the VP16 transcriptional activation domain. Science, 251, 87-90.
-
(1991)
Science
, vol.251
, pp. 87-90
-
-
Cress, W.D.1
Triezenberg, S.J.2
-
11
-
-
34248165959
-
Nine-amino-acid transactivation domain: Establishment and prediction utilities
-
Piskacek, S., Gregor, M., Nemethova, M., Grabner, M., Kovarik, P. and Piskacek, M. (2007) Nine-amino-acid transactivation domain: establishment and prediction utilities. Genomics, 89, 756-768.
-
(2007)
Genomics
, vol.89
, pp. 756-768
-
-
Piskacek, S.1
Gregor, M.2
Nemethova, M.3
Grabner, M.4
Kovarik, P.5
Piskacek, M.6
-
12
-
-
77958111633
-
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
-
Malik, S. and Roeder, R.G. (2010) The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat. Rev. Genet., 11, 761-772.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 761-772
-
-
Malik, S.1
Roeder, R.G.2
-
13
-
-
47249134314
-
Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex
-
Bourbon, H.M. (2008) Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex. Nucleic Acids Res., 36, 3993-4008.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 3993-4008
-
-
Bourbon, H.M.1
-
14
-
-
0346993714
-
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
-
Mittler, G., Stuhler, T., Santolin, L., Uhlmann, T., Kremmer, E., Lottspeich, F., Berti, L. and Meisterernst, M. (2003) A novel docking site on Mediator is critical for activation by VP16 in mammalian cells. EMBO J., 22, 6494-6504.
-
(2003)
EMBO J.
, vol.22
, pp. 6494-6504
-
-
Mittler, G.1
Stuhler, T.2
Santolin, L.3
Uhlmann, T.4
Kremmer, E.5
Lottspeich, F.6
Berti, L.7
Meisterernst, M.8
-
15
-
-
1442354965
-
The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator
-
Yang, F., DeBeaumont, R., Zhou, S. and Naar, A.M. (2004) The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator. Proc. Natl Acad. Sci. USA, 101, 2339-2344.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 2339-2344
-
-
Yang, F.1
Debeaumont, R.2
Zhou, S.3
Naar, A.M.4
-
16
-
-
77951083685
-
Kaposi's sarcoma-associated herpesvirus Lana-1 is a major activator of the serum response element and mitogen-activated protein kinase pathways via interactions with the Mediator complex
-
Roupelieva, M., Griffiths, S.J., Kremmer, E., Meisterernst, M., Viejo-Borbolla, A., Schulz, T. and Haas, J. (2010) Kaposi's sarcoma-associated herpesvirus Lana-1 is a major activator of the serum response element and mitogen-activated protein kinase pathways via interactions with the Mediator complex. J. Gen. Virol., 91, 1138-1149.
-
(2010)
J. Gen. Virol.
, vol.91
, pp. 1138-1149
-
-
Roupelieva, M.1
Griffiths, S.J.2
Kremmer, E.3
Meisterernst, M.4
Viejo-Borbolla, A.5
Schulz, T.6
Haas, J.7
-
17
-
-
57349188981
-
Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation
-
Yang, M., Hay, J. and Ruyechan, W.T. (2008) Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation. J. Virol., 82, 12154-12163.
-
(2008)
J. Virol.
, vol.82
, pp. 12154-12163
-
-
Yang, M.1
Hay, J.2
Ruyechan, W.T.3
-
18
-
-
34547812030
-
MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation
-
Lee, H.K., Park, U.H., Kim, E.J. and Um, S.J. (2007) MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation. EMBO J., 26, 3545-3557.
-
(2007)
EMBO J.
, vol.26
, pp. 3545-3557
-
-
Lee, H.K.1
Park, U.H.2
Kim, E.J.3
Um, S.J.4
-
19
-
-
78751558863
-
Med25 is required for RNA polymerase ii recruitment to specific promoters, thus regulating xenobiotic and lipid metabolism in human liver
-
Rana, R., Surapureddi, S., Kam, W., Ferguson, S. and Goldstein, J.A. (2011) Med25 is required for RNA polymerase ii recruitment to specific promoters, thus regulating xenobiotic and lipid metabolism in human liver. Mol. Cell Biol., 31, 466-481.
-
(2011)
Mol. Cell Biol.
, vol.31
, pp. 466-481
-
-
Rana, R.1
Surapureddi, S.2
Kam, W.3
Ferguson, S.4
Goldstein, J.A.5
-
20
-
-
79953242601
-
Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25
-
Nakamura, Y., Yamamoto, K., He, X., Otsuki, B., Kim, Y., Murao, H., Soeda, T., Tsumaki, N., Deng, J.M., Zhang, Z. et al. (2011) Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25. Nat. Commun., 2, 251.
-
(2011)
Nat. Commun.
, vol.2
, pp. 251
-
-
Nakamura, Y.1
Yamamoto, K.2
He, X.3
Otsuki, B.4
Kim, Y.5
Murao, H.6
Soeda, T.7
Tsumaki, N.8
Deng, J.M.9
Zhang, Z.10
-
21
-
-
0030939489
-
Expression of the PEA3 group of ETS-related transcription factors in human breast-cancer cells
-
Baert, J.L., Monte, D., Musgrove, E.A., Albagli, O., Sutherland, R.L. and de Launoit, Y. (1997) Expression of the PEA3 group of ETS-related transcription factors in human breast-cancer cells. Int. J. Cancer, 70, 590-597.
-
(1997)
Int. J. Cancer
, vol.70
, pp. 590-597
-
-
Baert, J.L.1
Monte, D.2
Musgrove, E.A.3
Albagli, O.4
Sutherland, R.L.5
De Launoit, Y.6
-
22
-
-
0032746017
-
Genomic organization of the human e1af gene, a member of Ets transcription factors
-
Coutte, L., Monte, D., Baert, J.L. and de Launoit, Y. (1999) Genomic organization of the human e1af gene, a member of Ets transcription factors. Gene, 240, 201-207.
-
(1999)
Gene
, vol.240
, pp. 201-207
-
-
Coutte, L.1
Monte, D.2
Baert, J.L.3
De Launoit, Y.4
-
23
-
-
0032560071
-
The transcription of the intercellular adhesion molecule-1 is regulated by Ets transcription factors
-
de Launoit, Y., Audette, M., Pelczar, H., Plaza, S. and Baert, J.L. (1998) The transcription of the intercellular adhesion molecule-1 is regulated by Ets transcription factors. Oncogene, 16, 2065-2073.
-
(1998)
Oncogene
, vol.16
, pp. 2065-2073
-
-
De Launoit, Y.1
Audette, M.2
Pelczar, H.3
Plaza, S.4
Baert, J.L.5
-
24
-
-
0037059812
-
ERM transactivation is up-regulated by the repression of DNA binding after the PKA phosphorylation of a consensus site at the edge of the ETS domain
-
Baert, J.L., Beaudoin, C., Coutte, L. and de Launoit, Y. (2002) ERM transactivation is up-regulated by the repression of DNA binding after the PKA phosphorylation of a consensus site at the edge of the ETS domain. J. Biol. Chem., 277, 1002-1012.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1002-1012
-
-
Baert, J.L.1
Beaudoin, C.2
Coutte, L.3
De Launoit, Y.4
-
25
-
-
33846311380
-
The 26S proteasome system degrades the ERM transcription factor and regulates its transcription-enhancing activity
-
Baert, J.L., Beaudoin, C., Monte, D., Degerny, C., Mauen, S. and de Launoit, Y. (2007) The 26S proteasome system degrades the ERM transcription factor and regulates its transcription-enhancing activity. Oncogene, 26, 415-424.
-
(2007)
Oncogene
, vol.26
, pp. 415-424
-
-
Baert, J.L.1
Beaudoin, C.2
Monte, D.3
Degerny, C.4
Mauen, S.5
De Launoit, Y.6
-
26
-
-
0037199915
-
Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1
-
Blais, A., Monte, D., Pouliot, F. and Labrie, C. (2002) Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1. J. Biol. Chem., 277, 31679-31693.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31679-31693
-
-
Blais, A.1
Monte, D.2
Pouliot, F.3
Labrie, C.4
-
27
-
-
79952444571
-
NMR structure of the human Mediator MED25 ACID domain
-
Bontems, F., Verger, A., Dewitte, F., Lens, Z., Baert, J.L., Ferreira, E., Launoit, Y.D., Sizun, C., Guittet, E., Villeret, V. et al. (2011) NMR structure of the human Mediator MED25 ACID domain. J. Struct. Biol., 174, 245-251.
-
(2011)
J. Struct. Biol.
, vol.174
, pp. 245-251
-
-
Bontems, F.1
Verger, A.2
Dewitte, F.3
Lens, Z.4
Baert, J.L.5
Ferreira, E.6
Launoit, Y.D.7
Sizun, C.8
Guittet, E.9
Villeret, V.10
-
28
-
-
80054025676
-
The Coactivator Activator CoAA regulates PEA3 group member transcriptional activity
-
Verreman, K., Baert, J.L., Verger, A., Drobecq, H., Ferreira, E., de Launoit, Y. and Monte, D. (2011) The Coactivator Activator CoAA regulates PEA3 group member transcriptional activity. Biochem. J., 439, 469-477.
-
(2011)
Biochem. J.
, vol.439
, pp. 469-477
-
-
Verreman, K.1
Baert, J.L.2
Verger, A.3
Drobecq, H.4
Ferreira, E.5
De Launoit, Y.6
Monte, D.7
-
29
-
-
33750335208
-
Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins
-
Quinlan, K.G., Nardini, M., Verger, A., Francescato, P., Yaswen, P., Corda, D., Bolognesi, M. and Crossley, M. (2006) Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol. Cell Biol., 26, 8159-8172.
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 8159-8172
-
-
Quinlan, K.G.1
Nardini, M.2
Verger, A.3
Francescato, P.4
Yaswen, P.5
Corda, D.6
Bolognesi, M.7
Crossley, M.8
-
30
-
-
78651489510
-
MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms
-
Affara, M., Dunmore, B.J., Sanders, D.A., Johnson, N., Print, C.G. and Charnock-Jones, D.S. (2011) MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms. BMC Genomics, 12, 43.
-
(2011)
BMC Genomics
, vol.12
, pp. 43
-
-
Affara, M.1
Dunmore, B.J.2
Sanders, D.A.3
Johnson, N.4
Print, C.G.5
Charnock-Jones, D.S.6
-
31
-
-
79953779234
-
Structure of the VP16 transactivator target in ARC/Mediator
-
Milbradt, A.G., Kulkarni, M., Yi, T., Takeuchi, K., Sun, Z.J., Luna, R.E., Selenko, P., Naar, A. and Wagner, G. (2011) Structure of the VP16 transactivator target in ARC/Mediator. Nat. Struct. Biol., 18, 410-415.
-
(2011)
Nat. Struct. Biol.
, vol.18
, pp. 410-415
-
-
Milbradt, A.G.1
Kulkarni, M.2
Yi, T.3
Takeuchi, K.4
Sun, Z.J.5
Luna, R.E.6
Selenko, P.7
Naar, A.8
Wagner, G.9
-
32
-
-
79953770655
-
The mediator MED25 activator interaction domain: Structure and cooperative binding of VP16 subdomains
-
Vojnic, E., Mourao, A., Seizl, M., Simon, B., Wenzeck, L., Lariviere, L., Baumli, S., Baumgart, K., Meisterernest, M., Sattler, M. et al. (2011) The mediator MED25 activator interaction domain: structure and cooperative binding of VP16 subdomains. Nat. Struct. Biol., 18, 404-409.
-
(2011)
Nat. Struct. Biol.
, vol.18
, pp. 404-409
-
-
Vojnic, E.1
Mourao, A.2
Seizl, M.3
Simon, B.4
Wenzeck, L.5
Lariviere, L.6
Baumli, S.7
Baumgart, K.8
Meisterernest, M.9
Sattler, M.10
-
33
-
-
0036158808
-
The H1 and H2 regions of the activation domain of herpes simplex virion protein 16 stimulate transcription through distinct molecular mechanisms
-
Ikeda, K., Stuehler, T. and Meisterernst, M. (2002) The H1 and H2 regions of the activation domain of herpes simplex virion protein 16 stimulate transcription through distinct molecular mechanisms. Genes Cells, 7, 49-58.
-
(2002)
Genes Cells
, vol.7
, pp. 49-58
-
-
Ikeda, K.1
Stuehler, T.2
Meisterernst, M.3
-
34
-
-
0033587187
-
Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein
-
Boyer, T.G., Martin, M.E., Lees, E., Ricciardi, R.P. and Berk, A.J. (1999) Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein. Nature, 399, 276-279.
-
(1999)
Nature
, vol.399
, pp. 276-279
-
-
Boyer, T.G.1
Martin, M.E.2
Lees, E.3
Ricciardi, R.P.4
Berk, A.J.5
-
35
-
-
0032493455
-
The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
-
Yuan, C.X., Ito, M., Fondell, J.D., Fu, Z.Y. and Roeder, R.G. (1998) The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. Proc. Natl Acad. Sci. USA, 95, 7939-7944.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 7939-7944
-
-
Yuan, C.X.1
Ito, M.2
Fondell, J.D.3
Fu, Z.Y.4
Roeder, R.G.5
-
36
-
-
0029118034
-
Molecular characterization of the ets-related human transcription factor ER81
-
Monte, D., Coutte, L., Baert, J.L., Angeli, I., Stehelin, D. and de Launoit, Y. (1995) Molecular characterization of the ets-related human transcription factor ER81. Oncogene, 11, 771-779.
-
(1995)
Oncogene
, vol.11
, pp. 771-779
-
-
Monte, D.1
Coutte, L.2
Baert, J.L.3
Angeli, I.4
Stehelin, D.5
De Launoit, Y.6
-
37
-
-
84859038513
-
ETV1, 4 and 5: An oncogenic subfamily of ETS transcription factors
-
Oh, S., Shin, S. and Janknecht, R. (2012) ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors. Biochim. Biophys. Acta, 1826, 1-12.
-
(2012)
Biochim. Biophys. Acta
, vol.1826
, pp. 1-12
-
-
Oh, S.1
Shin, S.2
Janknecht, R.3
-
38
-
-
52649149854
-
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression
-
Qin, L., Liao, L., Redmond, A., Young, L., Yuan, Y., Chen, H., O'Malley, B.W. and Xu, J. (2008) The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol. Cell Biol., 28, 5937-5950.
-
(2008)
Mol. Cell Biol.
, vol.28
, pp. 5937-5950
-
-
Qin, L.1
Liao, L.2
Redmond, A.3
Young, L.4
Yuan, Y.5
Chen, H.6
O'Malley, B.W.7
Xu, J.8
-
39
-
-
0035827698
-
PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2
-
Howe, L.R., Crawford, H.C., Subbaramaiah, K., Hassell, J.A., Dannenberg, A.J. and Brown, A.M. (2001) PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2. J. Biol. Chem., 276, 20108-20115.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20108-20115
-
-
Howe, L.R.1
Crawford, H.C.2
Subbaramaiah, K.3
Hassell, J.A.4
Dannenberg, A.J.5
Brown, A.M.6
-
40
-
-
80455155050
-
Interactions between subunits of the Mediator complex with gene-specific transcription factors
-
Borggrefe, T. and Yue, X. (2011) Interactions between subunits of the Mediator complex with gene-specific transcription factors. Semin. Cell Dev. Biol., 22, 759-768.
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 759-768
-
-
Borggrefe, T.1
Yue, X.2
-
41
-
-
0033105821
-
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators
-
Ito, M., Yuan, C.X., Malik, S., Gu, W., Fondell, J.D., Yamamura, S., Fu, Z.Y., Zhang, X., Qin, J. and Roeder, R.G. (1999) Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol. Cell, 3, 361-370.
-
(1999)
Mol. Cell
, vol.3
, pp. 361-370
-
-
Ito, M.1
Yuan, C.X.2
Malik, S.3
Gu, W.4
Fondell, J.D.5
Yamamura, S.6
Fu, Z.Y.7
Zhang, X.8
Qin, J.9
Roeder, R.G.10
-
42
-
-
77953293350
-
P53 activates transcription by directing structural shifts in Mediator
-
Meyer, K.D., Lin, S.C., Bernecky, C., Gao, Y. and Taatjes, D.J. (2010) p53 activates transcription by directing structural shifts in Mediator. Nat. Struct. Mol. Biol., 17, 753-760.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 753-760
-
-
Meyer, K.D.1
Lin, S.C.2
Bernecky, C.3
Gao, Y.4
Taatjes, D.J.5
-
43
-
-
33747053907
-
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis
-
Yang, F., Vought, B.W., Satterlee, J.S., Walker, A.K., Jim Sun, Z.Y., Watts, J.L., DeBeaumont, R., Saito, R.M., Hyberts, S.G., Yang, S. et al. (2006) An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis. Nature, 442, 700-704.
-
(2006)
Nature
, vol.442
, pp. 700-704
-
-
Yang, F.1
Vought, B.W.2
Satterlee, J.S.3
Walker, A.K.4
Jim Sun, Z.Y.5
Watts, J.L.6
Debeaumont, R.7
Saito, R.M.8
Hyberts, S.G.9
Yang, S.10
-
44
-
-
66149113985
-
Analysis of the varicella-zoster virus IE62 N-terminal acidic transactivating domain and its interaction with the human mediator complex
-
Yamamoto, S., Eletsky, A., Szyperski, T., Hay, J. and Ruyechan, W.T. (2009) Analysis of the varicella-zoster virus IE62 N-terminal acidic transactivating domain and its interaction with the human mediator complex. J. Virol., 83, 6300-6305.
-
(2009)
J. Virol.
, vol.83
, pp. 6300-6305
-
-
Yamamoto, S.1
Eletsky, A.2
Szyperski, T.3
Hay, J.4
Ruyechan, W.T.5
-
45
-
-
81255140709
-
The acidic transcription activator gcn4 binds the mediator subunit gal11/med15 using a simple protein interface forming a fuzzy complex
-
Brzovic, P.S., Heikaus, C.C., Kisselev, L., Vernon, R., Herbig, E., Pacheco, D., Warfield, L., Littlefield, P., Baker, D., Klevit, R.E. et al. (2011) The acidic transcription activator gcn4 binds the mediator subunit gal11/med15 using a simple protein interface forming a fuzzy complex. Mol. Cell, 44, 942-953.
-
(2011)
Mol. Cell
, vol.44
, pp. 942-953
-
-
Brzovic, P.S.1
Heikaus, C.C.2
Kisselev, L.3
Vernon, R.4
Herbig, E.5
Pacheco, D.6
Warfield, L.7
Littlefield, P.8
Baker, D.9
Klevit, R.E.10
-
46
-
-
79960600766
-
Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF)
-
Mas, C., Lussier-Price, M., Soni, S., Morse, T., Arseneault, G., Di Lello, P., Lafrance-Vanasse, J., Bieker, J.J. and Omichinski, J.G. (2011) Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF). Proc. Natl Acad. Sci. USA, 108, 10484-10489.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 10484-10489
-
-
Mas, C.1
Lussier-Price, M.2
Soni, S.3
Morse, T.4
Arseneault, G.5
Di Lello, P.6
Lafrance-Vanasse, J.7
Bieker, J.J.8
Omichinski, J.G.9
-
47
-
-
33745214419
-
Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53
-
Di Lello, P., Jenkins, L.M., Jones, T.N., Nguyen, B.D., Hara, T., Yamaguchi, H., Dikeakos, J.D., Appella, E., Legault, P. and Omichinski, J.G. (2006) Structure of the Tfb1/p53 complex: insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol. Cell, 22, 731-740.
-
(2006)
Mol. Cell
, vol.22
, pp. 731-740
-
-
Di Lello, P.1
Jenkins, L.M.2
Jones, T.N.3
Nguyen, B.D.4
Hara, T.5
Yamaguchi, H.6
Dikeakos, J.D.7
Appella, E.8
Legault, P.9
Omichinski, J.G.10
-
48
-
-
0030575937
-
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
-
Kussie, P.H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A.J. and Pavletich, N.P. (1996) Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science, 274, 948-953.
-
(1996)
Science
, vol.274
, pp. 948-953
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
Elenbaas, B.4
Moreau, J.5
Levine, A.J.6
Pavletich, N.P.7
-
49
-
-
34548383489
-
Design of multi-specificity in protein interfaces
-
Humphris, E.L. and Kortemme, T. (2007) Design of multi-specificity in protein interfaces. PLoS Comput. Biol., 3, e164.
-
(2007)
PLoS Comput. Biol.
, vol.3
-
-
Humphris, E.L.1
Kortemme, T.2
-
50
-
-
0027169855
-
Transcriptional activation by the acidic domain of Vmw65 requires the integrity of the domain and involves additional determinants distinct from those necessary for TFIIB binding
-
Walker, S., Greaves, R. and O'Hare, P. (1993) Transcriptional activation by the acidic domain of Vmw65 requires the integrity of the domain and involves additional determinants distinct from those necessary for TFIIB binding. Mol. Cell Biol., 13, 5233-5244.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 5233-5244
-
-
Walker, S.1
Greaves, R.2
O'Hare, P.3
-
51
-
-
0034459504
-
In vivo requirement of activator-specific binding targets of mediator
-
Park, J.M., Kim, H.S., Han, S.J., Hwang, M.S., Lee, Y.C. and Kim, Y.J. (2000) In vivo requirement of activator-specific binding targets of mediator. Mol. Cell Biol., 20, 8709-8719.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 8709-8719
-
-
Park, J.M.1
Kim, H.S.2
Han, S.J.3
Hwang, M.S.4
Lee, Y.C.5
Kim, Y.J.6
-
52
-
-
34247642450
-
Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors
-
Paoletti, A.C., Parmely, T.J., Tomomori-Sato, C., Sato, S., Zhu, D., Conaway, R.C., Conaway, J.W., Florens, L. and Washburn, M.P. (2006) Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors. Proc. Natl Acad. Sci. USA, 103, 18928-18933.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 18928-18933
-
-
Paoletti, A.C.1
Parmely, T.J.2
Tomomori-Sato, C.3
Sato, S.4
Zhu, D.5
Conaway, R.C.6
Conaway, J.W.7
Florens, L.8
Washburn, M.P.9
-
53
-
-
2942575993
-
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology
-
Sato, S., Tomomori-Sato, C., Parmely, T.J., Florens, L., Zybailov, B., Swanson, S.K., Banks, C.A., Jin, J., Cai, Y., Washburn, M.P. et al. (2004) A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Mol. Cell, 14, 685-691.
-
(2004)
Mol. Cell
, vol.14
, pp. 685-691
-
-
Sato, S.1
Tomomori-Sato, C.2
Parmely, T.J.3
Florens, L.4
Zybailov, B.5
Swanson, S.K.6
Banks, C.A.7
Jin, J.8
Cai, Y.9
Washburn, M.P.10
-
54
-
-
34047243849
-
The VP16 activation domain establishes an active mediator lacking CDK8 in vivo
-
Uhlmann, T., Boeing, S., Lehmbacher, M. and Meisterernst, M. (2007) The VP16 activation domain establishes an active mediator lacking CDK8 in vivo. J. Biol. Chem., 282, 2163-2173.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2163-2173
-
-
Uhlmann, T.1
Boeing, S.2
Lehmbacher, M.3
Meisterernst, M.4
-
55
-
-
38549087992
-
Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression
-
Ge, K., Cho, Y.W., Guo, H., Hong, T.B., Guermah, M., Ito, M., Yu, H., Kalkum, M. and Roeder, R.G. (2008) Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression. Mol. Cell Biol., 28, 1081-1091.
-
(2008)
Mol. Cell Biol.
, vol.28
, pp. 1081-1091
-
-
Ge, K.1
Cho, Y.W.2
Guo, H.3
Hong, T.B.4
Guermah, M.5
Ito, M.6
Yu, H.7
Kalkum, M.8
Roeder, R.G.9
-
56
-
-
66149122282
-
Two modes of transcriptional activation at native promoters by NF-kappaB p65
-
van Essen, D., Engist, B., Natoli, G. and Saccani, S. (2009) Two modes of transcriptional activation at native promoters by NF-kappaB p65. PLoS Biol., 7, e73.
-
(2009)
PLoS Biol.
, vol.7
-
-
Van Essen, D.1
Engist, B.2
Natoli, G.3
Saccani, S.4
-
57
-
-
0038558164
-
A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription
-
Huang, Z.Q., Li, J., Sachs, L.M., Cole, P.A. and Wong, J. (2003) A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription. EMBO J., 22, 2146-2155.
-
(2003)
EMBO J.
, vol.22
, pp. 2146-2155
-
-
Huang, Z.Q.1
Li, J.2
Sachs, L.M.3
Cole, P.A.4
Wong, J.5
-
58
-
-
0029793329
-
Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression
-
Schneikert, J., Peterziel, H., Defossez, P.A., Klocker, H., Launoit, Y. and Cato, A.C. (1996) Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression. J. Biol. Chem., 271, 23907-23913.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23907-23913
-
-
Schneikert, J.1
Peterziel, H.2
Defossez, P.A.3
Klocker, H.4
Launoit, Y.5
Cato, A.C.6
-
59
-
-
79952350060
-
ERbeta and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells
-
Chen, Y., Chen, L., Li, J.Y., Mukaida, N., Wang, Q., Yang, C., Yin, W.J., Zeng, X.H., Jin, W. and Shao, Z.M. (2011) ERbeta and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells. Cancer Biol. Ther., 11, 497-511.
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 497-511
-
-
Chen, Y.1
Chen, L.2
Li, J.Y.3
Mukaida, N.4
Wang, Q.5
Yang, C.6
Yin, W.J.7
Zeng, X.H.8
Jin, W.9
Shao, Z.M.10
-
60
-
-
80455164549
-
Mediator-dependent nuclear receptor function
-
Chen, W. and Roeder, R.G. (2011) Mediator-dependent nuclear receptor function. Semin. Cell Dev. Biol., 22, 749-758.
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 749-758
-
-
Chen, W.1
Roeder, R.G.2
|