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Volumn 8, Issue 5, 2013, Pages

Modeling Stem Cell Induction Processes

Author keywords

[No Author keywords available]

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

EID: 84877248281     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060240     Document Type: Article
Times cited : (5)

References (58)
  • 1
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • Jaenisch R, Young R, (2008) Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132: 567-582.
    • (2008) Cell , vol.132 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 2
    • 67649920749 scopus 로고    scopus 로고
    • Growth factors, matrices, and forces combine and control stem cells
    • Discher D, Mooney D, Zandstra P, (2009) Growth factors, matrices, and forces combine and control stem cells. Science 324: 1673.
    • (2009) Science , vol.324 , pp. 1673
    • Discher, D.1    Mooney, D.2    Zandstra, P.3
  • 3
    • 63049090064 scopus 로고    scopus 로고
    • A fresh look at iPS cells
    • Yamanaka S, (2009) A fresh look at iPS cells. Cell 137: 13-17.
    • (2009) Cell , vol.137 , pp. 13-17
    • Yamanaka, S.1
  • 4
    • 70349315647 scopus 로고    scopus 로고
    • Induced human pluripotent stem cells: Promises and open questions
    • Rolletschek A, Wobus A, (2009) Induced human pluripotent stem cells: Promises and open questions. Biol Chem 390: 845-849.
    • (2009) Biol Chem , vol.390 , pp. 845-849
    • Rolletschek, A.1    Wobus, A.2
  • 5
    • 50149108172 scopus 로고    scopus 로고
    • The promise of human induced pluripotent stem cells for research and therapy
    • Nishikawa S, Goldstein R, Nierras C, (2008) The promise of human induced pluripotent stem cells for research and therapy. Nature Rev Mol Cel Biol 9: 725-729.
    • (2008) Nature Rev Mol Cel Biol , vol.9 , pp. 725-729
    • Nishikawa, S.1    Goldstein, R.2    Nierras, C.3
  • 6
    • 79551586415 scopus 로고    scopus 로고
    • Policy uncertainty and the conduct of stem cell research
    • Levine A, (2011) Policy uncertainty and the conduct of stem cell research. Cell Stem Cell 8: 132-135.
    • (2011) Cell Stem Cell , vol.8 , pp. 132-135
    • Levine, A.1
  • 7
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S, (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 8
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5
  • 9
    • 77956260872 scopus 로고    scopus 로고
    • Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells
    • Guenther M, Frampton G, Soldner F, Hockemeyer D, Mitalipova M, et al. (2010) Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. Cell Stem Cell 7: 249-257.
    • (2010) Cell Stem Cell , vol.7 , pp. 249-257
    • Guenther, M.1    Frampton, G.2    Soldner, F.3    Hockemeyer, D.4    Mitalipova, M.5
  • 10
    • 69949104478 scopus 로고    scopus 로고
    • Adultmice generated from induced pluripotent stem cells
    • BolandM, Hazen J, Nazor K, Rodriguez A, GiffordW, et al, (2009) Adultmice generated from induced pluripotent stem cells. Nature 461: 91-94.
    • (2009) Nature , vol.461 , pp. 91-94
    • Boland, M.1    Hazen, J.2    Nazor, K.3    Rodriguez, A.4    Gifford, W.5
  • 11
    • 67849133023 scopus 로고    scopus 로고
    • iPS cells can support full-term development of tetraploid blastocyst-complemented embryos
    • Kang L, Wang J, Zhang Y, Kou Z, Gao S, (2009) iPS cells can support full-term development of tetraploid blastocyst-complemented embryos. Cell Stem Cell 5: 135-138.
    • (2009) Cell Stem Cell , vol.5 , pp. 135-138
    • Kang, L.1    Wang, J.2    Zhang, Y.3    Kou, Z.4    Gao, S.5
  • 12
    • 69949089630 scopus 로고    scopus 로고
    • iPS cells produce viable mice through tetraploid complementation
    • Zhao X, Li W, Lv Z, Liu L, Tong M, et al. (2009) iPS cells produce viable mice through tetraploid complementation. Nature 461: 86-90.
    • (2009) Nature , vol.461 , pp. 86-90
    • Zhao, X.1    Li, W.2    Lv, Z.3    Liu, L.4    Tong, M.5
  • 13
    • 77955850887 scopus 로고    scopus 로고
    • Advances in reprogramming somatic cells to induced pluripotent stem cells
    • PatelM, Yang S, (2010) Advances in reprogramming somatic cells to induced pluripotent stem cells. Stem Cell Rev 6: 367-380.
    • (2010) Stem Cell Rev , vol.6 , pp. 367-380
    • Patel, M.1    Yang, S.2
  • 14
    • 60649084367 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: Current progress and potential for regenerative medicine
    • Amabile G, Meissner A, (2009) Induced pluripotent stem cells: Current progress and potential for regenerative medicine. Trends Mol Med 15: 59-68.
    • (2009) Trends Mol Med , vol.15 , pp. 59-68
    • Amabile, G.1    Meissner, A.2
  • 15
    • 79952261648 scopus 로고    scopus 로고
    • Stem cells: The dark side of induced pluripotency
    • Pera M, (2011) Stem cells: The dark side of induced pluripotency. Nature 471: 46-47.
    • (2011) Nature , vol.471 , pp. 46-47
    • Pera, M.1
  • 16
    • 69149110152 scopus 로고    scopus 로고
    • Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation
    • Papapetrou E, Tomishima M, Chambers S, Mica Y, Reed E, et al. (2009) Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc Natl Acad Sci USA 106: 12759.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 12759
    • Papapetrou, E.1    Tomishima, M.2    Chambers, S.3    Mica, Y.4    Reed, E.5
  • 17
    • 62949220231 scopus 로고    scopus 로고
    • Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
    • Feng B, Ng J, Heng J, Ng H, (2009) Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 4: 301-312.
    • (2009) Cell Stem Cell , vol.4 , pp. 301-312
    • Feng, B.1    Ng, J.2    Heng, J.3    Ng, H.4
  • 18
    • 54949115497 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic fibroblasts by oct4 and klf4 with small-molecule compounds
    • Shi Y, Desponts C, Do J, Hahm H, Schöler H, et al. (2008) Induction of pluripotent stem cells from mouse embryonic fibroblasts by oct4 and klf4 with small-molecule compounds. Cell stem cell 3: 568-574.
    • (2008) Cell Stem Cell , vol.3 , pp. 568-574
    • Shi, Y.1    Desponts, C.2    Do, J.3    Hahm, H.4    Schöler, H.5
  • 19
    • 67650095196 scopus 로고    scopus 로고
    • Elite and stochastic models for induced pluripotent stem cell generation
    • Yamanaka S, (2009) Elite and stochastic models for induced pluripotent stem cell generation. Nature 460: 49-52.
    • (2009) Nature , vol.460 , pp. 49-52
    • Yamanaka, S.1
  • 20
    • 71449109765 scopus 로고    scopus 로고
    • Direct cell reprogramming is a stochastic process amenable to acceleration
    • Hanna J, Saha K, Pando B, Van Zon J, Lengner C, et al. (2009) Direct cell reprogramming is a stochastic process amenable to acceleration. Nature 462: 595-601.
    • (2009) Nature , vol.462 , pp. 595-601
    • Hanna, J.1    Saha, K.2    Pando, B.3    Van Zon, J.4    Lengner, C.5
  • 21
    • 68049139696 scopus 로고    scopus 로고
    • Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells
    • Kalmar T, Lim C, Hayward P, Mu∼noz-Descalzo S, Nichols J, et al. (2009) Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells. PLoS Biol 7: e1000149.
    • (2009) PLoS Biol , vol.7
    • Kalmar, T.1    Lim, C.2    Hayward, P.3    Munoz-Descalzo, S.4    Nichols, J.5
  • 22
    • 55649104699 scopus 로고    scopus 로고
    • A computational model for understanding stem cell, trophectoderm and endoderm lineage determination
    • Chickarmane V, Peterson C, (2008) A computational model for understanding stem cell, trophectoderm and endoderm lineage determination. PLoS One 3: 3478.
    • (2008) PLoS One , vol.3 , pp. 3478
    • Chickarmane, V.1    Peterson, C.2
  • 23
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer L, Lee T, Cole M, Johnstone S, Levine S, et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 947-956.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.1    Lee, T.2    Cole, M.3    Johnstone, S.4    Levine, S.5
  • 24
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee T, Jenner R, Boyer L, Guenther M, Levine S, et al. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125: 301-313.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.1    Jenner, R.2    Boyer, L.3    Guenther, M.4    Levine, S.5
  • 25
    • 21644434480 scopus 로고    scopus 로고
    • Transcriptional regulation of nanog by OCT4 and SOX2
    • Rodda D, Chew J, Lim L, Loh Y, Wang B, et al. (2005) Transcriptional regulation of nanog by OCT4 and SOX2. J Biol Chem 280: 24731-24737.
    • (2005) J Biol Chem , vol.280 , pp. 24731-24737
    • Rodda, D.1    Chew, J.2    Lim, L.3    Loh, Y.4    Wang, B.5
  • 26
    • 14844359620 scopus 로고    scopus 로고
    • Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression
    • Kuroda T, Tada M, Kubota H, Kimura H, Hatano S, et al. (2005) Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol Cell Biol 25: 2475-2485.
    • (2005) Mol Cell Biol , vol.25 , pp. 2475-2485
    • Kuroda, T.1    Tada, M.2    Kubota, H.3    Kimura, H.4    Hatano, S.5
  • 28
    • 70350627509 scopus 로고    scopus 로고
    • Epigenetic reversion of postimplantation epiblast to pluripotent embryonic stem cells
    • Bao S, Tang F, Li X, Hayashi K, Gillich A, et al. (2009) Epigenetic reversion of postimplantation epiblast to pluripotent embryonic stem cells. Nature 461: 1292-1295.
    • (2009) Nature , vol.461 , pp. 1292-1295
    • Bao, S.1    Tang, F.2    Li, X.3    Hayashi, K.4    Gillich, A.5
  • 29
    • 46449094276 scopus 로고    scopus 로고
    • Dissecting direct reprogramming through integrative genomic analysis
    • Mikkelsen T, Hanna J, Zhang X, Ku M, Wernig M, et al. (2008) Dissecting direct reprogramming through integrative genomic analysis. Nature 454: 49-55.
    • (2008) Nature , vol.454 , pp. 49-55
    • Mikkelsen, T.1    Hanna, J.2    Zhang, X.3    Ku, M.4    Wernig, M.5
  • 30
    • 64249157351 scopus 로고    scopus 로고
    • Epigenetic reprogramming and induced pluripotency
    • Hochedlinger K, Plath K, (2009) Epigenetic reprogramming and induced pluripotency. Development 136: 509-523.
    • (2009) Development , vol.136 , pp. 509-523
    • Hochedlinger, K.1    Plath, K.2
  • 31
    • 37549050193 scopus 로고    scopus 로고
    • Epigenetics in embryonic stem cells: Regulation of pluripotency and differentiation
    • Atkinson S, Armstrong L, (2008) Epigenetics in embryonic stem cells: Regulation of pluripotency and differentiation. Cell Tissue Res 331: 23-29.
    • (2008) Cell Tissue Res , vol.331 , pp. 23-29
    • Atkinson, S.1    Armstrong, L.2
  • 32
    • 44049088472 scopus 로고    scopus 로고
    • Requirement of Nanog dimerization for stem cell self-renewal and pluripotency
    • Wang J, Levasseur D, Orkin S, (2008) Requirement of Nanog dimerization for stem cell self-renewal and pluripotency. Proc Natl Acad Sci USA 105: 6326-6331.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6326-6331
    • Wang, J.1    Levasseur, D.2    Orkin, S.3
  • 33
    • 0042161878 scopus 로고    scopus 로고
    • Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers
    • Reményi A, Lins K, Nissen L, Reinbold R, Schöler H, et al. (2003) Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev 17: 2048-2059.
    • (2003) Genes Dev , vol.17 , pp. 2048-2059
    • Reményi, A.1    Lins, K.2    Nissen, L.3    Reinbold, R.4    Schöler, H.5
  • 34
    • 0346462991 scopus 로고    scopus 로고
    • Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1· Sox2·Hoxb1-DNA ternary transcription factor complex
    • Williams D, Cai M, Clore G, (2004) Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1· Sox2·Hoxb1-DNA ternary transcription factor complex. J Biol Chem 279: 1449-1457.
    • (2004) J Biol Chem , vol.279 , pp. 1449-1457
    • Williams, D.1    Cai, M.2    Clore, G.3
  • 35
    • 79951859664 scopus 로고    scopus 로고
    • Epigenetics of induced pluripotency, the seven-headed dragon
    • Djuric U, Ellis J, (2010) Epigenetics of induced pluripotency, the seven-headed dragon. Stem Cell Res Ther 1: 3.
    • (2010) Stem Cell Res Ther , vol.1 , pp. 3
    • Djuric, U.1    Ellis, J.2
  • 36
    • 84873801555 scopus 로고    scopus 로고
    • Systematic identification of signal-activated stochastic gene regulation
    • Neuert G, Munsky B, Tan RZ, Teytelman L, Khammash M, et al. (2013) Systematic identification of signal-activated stochastic gene regulation. Science 339: 584-587.
    • (2013) Science , vol.339 , pp. 584-587
    • Neuert, G.1    Munsky, B.2    Tan, R.Z.3    Teytelman, L.4    Khammash, M.5
  • 38
    • 25144450143 scopus 로고    scopus 로고
    • Contributions of low molecule number and chromosomal positioning to stochastic gene expression
    • Becskei A, Kaufmann BB, van Oudenaarden A, (2005) Contributions of low molecule number and chromosomal positioning to stochastic gene expression. Nature genetics 37: 937-944.
    • (2005) Nature Genetics , vol.37 , pp. 937-944
    • Becskei, A.1    Kaufmann, B.B.2    van Oudenaarden, A.3
  • 39
    • 2942718723 scopus 로고    scopus 로고
    • Control of stochasticity in eukaryotic gene expression
    • Raser JM, O'Shea EK, (2004) Control of stochasticity in eukaryotic gene expression. Science Signalling 304: 1811.
    • (2004) Science Signalling , vol.304 , pp. 1811
    • Raser, J.M.1    O'Shea, E.K.2
  • 43
    • 57449110975 scopus 로고    scopus 로고
    • Stochasticity and traffic jams in the transcription of ribosomal rna: Intriguing role of termination and antitermination
    • Klumpp S, Hwa T, (2008) Stochasticity and traffic jams in the transcription of ribosomal rna: Intriguing role of termination and antitermination. Proceedings of the National Academy of Sciences 105: 18159-18164.
    • (2008) Proceedings of the National Academy of Sciences , vol.105 , pp. 18159-18164
    • Klumpp, S.1    Hwa, T.2
  • 46
    • 19544379881 scopus 로고    scopus 로고
    • Stochasticity in gene expression: From theories to phenotypes
    • Kærn M, Elston T, Blake W, Collins J, (2005) Stochasticity in gene expression: From theories to phenotypes. Nat Rev Genet 6: 451-464.
    • (2005) Nat Rev Genet , vol.6 , pp. 451-464
    • Kærn, M.1    Elston, T.2    Blake, W.3    Collins, J.4
  • 47
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical reactions
    • Gillespie D, (1977) Exact stochastic simulation of coupled chemical reactions. J Phys Chem 81: 2340-2361.
    • (1977) J Phys Chem , vol.81 , pp. 2340-2361
    • Gillespie, D.1
  • 50
    • 35148845584 scopus 로고    scopus 로고
    • Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
    • Meissner A, Wernig M, Jaenisch R, (2007) Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nature biotechnology 25: 1177-1181.
    • (2007) Nature Biotechnology , vol.25 , pp. 1177-1181
    • Meissner, A.1    Wernig, M.2    Jaenisch, R.3
  • 51
    • 69349089552 scopus 로고    scopus 로고
    • Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells
    • Eminli S, Foudi A, StadtfeldM,Maherali N, Ahfeldt T, et al. (2009) Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. Nat Genetics 41: 968-976.
    • (2009) Nat Genetics , vol.41 , pp. 968-976
    • Eminli, S.1    Foudi, A.2    Stadtfeld, M.3    Maherali, N.4    Ahfeldt, T.5
  • 52
    • 70350536767 scopus 로고    scopus 로고
    • A small-molecule inhibitor of tgf-b signaling replaces sox2 in reprogramming by inducing nanog
    • Loh K, Carter A, Di Giorgio F, Koszka K, Huangfu D, et al. (2009) A small-molecule inhibitor of tgf-b signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 5: 491-503.
    • (2009) Cell Stem Cell , vol.5 , pp. 491-503
    • Loh, K.1    Carter, A.2    Di Giorgio, F.3    Koszka, K.4    Huangfu, D.5
  • 53
    • 77950965653 scopus 로고    scopus 로고
    • Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes
    • Mali P, Chou B, Yen J, Ye Z, Zou J, et al. (2010) Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells 28: 713-720.
    • (2010) Stem Cells , vol.28 , pp. 713-720
    • Mali, P.1    Chou, B.2    Yen, J.3    Ye, Z.4    Zou, J.5
  • 54
    • 78650915547 scopus 로고    scopus 로고
    • Generation of ipscs from mouse fibroblasts with a single gene, oct4, and small molecules
    • Li Y, Zhang Q, Yin X, Yang W, Du Y, et al. (2010) Generation of ipscs from mouse fibroblasts with a single gene, oct4, and small molecules. Cell research 21: 196-204.
    • (2010) Cell Research , vol.21 , pp. 196-204
    • Li, Y.1    Zhang, Q.2    Yin, X.3    Yang, W.4    Du, Y.5
  • 55
    • 84866992567 scopus 로고    scopus 로고
    • A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and ips cell generation
    • Li Z, Rana T, (2012) A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and ips cell generation. Nature Communications 3: 1085.
    • (2012) Nature Communications , vol.3 , pp. 1085
    • Li, Z.1    Rana, T.2
  • 57
    • 79952264847 scopus 로고    scopus 로고
    • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
    • Lister R, Pelizzola M, Kida Y, Hawkins R, Nery J, et al. (2011) Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 471: 68-73.
    • (2011) Nature , vol.471 , pp. 68-73
    • Lister, R.1    Pelizzola, M.2    Kida, Y.3    Hawkins, R.4    Nery, J.5
  • 58
    • 84863760388 scopus 로고    scopus 로고
    • Determination of mammalian cell counts, cell size and cell health using the moxi z mini automated cell counter
    • Dittami G, Sethi M, Rabbitt R, Ayliffe H (2012) Determination of mammalian cell counts, cell size and cell health using the moxi z mini automated cell counter. Journal of visualized experiments: JoVE.
    • (2012) Journal of visualized experiments: JoVE
    • Dittami, G.1    Sethi, M.2    Rabbitt, R.3    Ayliffe, H.4


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