Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y6 activation of the phospholipase C/inositol trisphosphate pathway

FASEB Journal

Volumn 27, Issue 5, 2013, Pages 1895-1903

  Yu, Weiqun ^a,b   Sun, Xiaofeng ^b   Robson, Simon C ^b   Hill, Warren G ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Detrusor; Micturition; Myography; Uridine nucleotides; Urinary tract

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1; INOSITOL TRISPHOSPHATE; NUCLEOTIDASE; PHOSPHOLIPASE C; PURINERGIC P2X RECEPTOR; PURINERGIC P2Y6 RECEPTOR; UNCLASSIFIED DRUG; XESTOSPONGIN C;

ANIMAL EXPERIMENT; ARTICLE; BLADDER CONTRACTION; BLADDER DYSFUNCTION; BLADDER SMOOTH MUSCLE; CONTROLLED STUDY; ENZYME ACTIVATION; IN VIVO STUDY; MOUSE; MUSCLE TONE; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGENS, CD; APYRASE; ESTRENES; INOSITOL 1,4,5-TRISPHOSPHATE; MICE; MUSCLE CONTRACTION; PYRROLIDINONES; RECEPTORS, PURINERGIC P2; RECEPTORS, PURINERGIC P2X1; SIGNAL TRANSDUCTION; TYPE C PHOSPHOLIPASES; URIDINE DIPHOSPHATE; URINARY BLADDER;

MUS;

EID: 84877152107     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-219006     Document Type: Article

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