A quantitative study of atropine-resistant contractile responses in human detrusor smooth muscle, from stable, unstable and obstructed bladders

Journal of Urology

Volumn 162, Issue 5, 1999, Pages 1833-1839

  Bayliss, M ^b   Wu, C ^b   Newgreen, D ^b   Mundy, A R ^b   Fry, C H ^a  

^a INSTITUTE OF UROLOGY AND NEPHROLOGY   (United Kingdom)

^b NONE

Author keywords

Cholinergic; Human detrusor; Obstructed bladder; Purinergic; Unstable bladder

Indexed keywords

ADENOSINE TRIPHOSPHATE; ATROPINE; CARBACHOL; CHOLINERGIC RECEPTOR STIMULATING AGENT;

ARTICLE; BLADDER DYSFUNCTION; BLADDER OBSTRUCTION; CELL FUNCTION; CONTROLLED STUDY; DETRUSOR MUSCLE; ELECTROSTIMULATION; HUMAN; HUMAN TISSUE; MUSCLE CONTRACTION; MUSCLE EXCITATION; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0032828697     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)68247-X     Document Type: Article

References (27)

1. Weil, A., Miege, B., Rottenberg, R. and Krauer, F.: Clinical significance of urethral instability. Obstet. Gynecol., 68: 106, 1986.
2. Palfrey, E. L., Fry, C. H. and Shuttleworth, K. E.: A new in vitro microsuperfusion technique for investigation of human detrusor muscle. Br. J. Urol., 56: 635, 1984.
3. Sibley, G. N.: A comparison of spontaneous and nerve-mediated activity in bladder muscle from man, pig and rabbit. J. Physiol., 354: 431, 1984.
4. Tong, Y. C., Hung, Y. C., Shinozuka, K., Kunitomo, M. and Cheng, J. T.: Evidence of adenosine 5′-triphosphate release from nerve and P2X-purinoceptor mediated contraction during electrical stimulation of rat urinary bladder smooth muscle. J. Urol., 158: 1973, 1997.
5. Harrison, S. C., Hunnam, G. R., Farman, P., Ferguson, D. R. and Doyle, P. T.: Bladder instability and denervation in patients with bladder outflow obstruction. Br. J. Urol., 60: 519, 1987.
6. Kinder, R. B. and Mundy, A. R.: Pathophysiology of idiopathic detrusor instability and detrusor hyper-reflexia. An in vitro study of human detrusor muscle. Br. J. Urol., 60: 509, 1987.
7. German, K., Bedwani, J., Davies, J., Brading, A. F. and Stephenson, T. P.: Physiological and morphometric studies into the pathophysiology of detrusor hyperreflexia in neuropathic patients. J. Urol., 153: 1678, 1995.
8. Yokoyama, O., Nagano, K., Kawaguchi, K. and Hisazumi, H.: The response of the detrusor muscle to acetylcholine in patients with infravesical obstruction. Urol. Res., 19: 117, 1991.
9. King, J. A., Huddart, H. and Staff, W. G.: Effect of choline ester analogues, noradrenaline and nifedipine on normal and hypertrophied human urinary bladder detrusor muscle. Gen. Pharmacol., 30: 131, 1998.
10. Sjogren, C., Andersson, K-E., Husted, S., Mattiasson, A. and Moller-Madsen, B.: Atropine resistance of transmurally stimulated isolated human bladder muscle. J. Urol., 128: 1368, 1982.
11. Palea, S., Artibani, W., Ostardo, E., Trist, D. G. and Pietra, C.: Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis. J. Urol., 150: 2007, 1993.
12. Ruggieri, M. R., Whitmore, K. E. and Levin, R. M.: Bladder purinergic receptors. J. Urol., 144: 176, 1990.
13. Tagliani, M., Candura, S. M., Di Nucci, A., Franceschetti, G. P., D'Agostino, G., Ricotti, P., Fiore, E. and Tonini, M.: A reappraisal of the nature of the atropine-resistant contraction to electrical field stimulation in the human isolated detrusor muscle. N. Schmeid. Arch. Pharmacol., 356: 750, 1997.
14. Artibani, W.: Diagnosis and significance of idiopathic overactive bladder. Urology, 50 (6A suppl): 25, 1997.
15. Liston, T. G., Palfrey, E. L. H., Raimbach, S. J. and Fry, C. H.: The effects of pH on human and ferret detrusor muscle function. J. Physiol., 432: 1, 1991.
16. Appell, R. A.: Bladder instability in patients with prostatic hypertrophy. Postgrad. Med. J., 57: 640, 1981.
17. Bo, X., Fischer, B., Maillard, M., Jacobson, K. A. and Burnstock, G.: Comparative studies on the affinities of ATP derivatives for P2X-purinoceptors in rat urinary bladder. Br. J. Pharmacol., 112: 1151, 1994.
18. Buell, G., Collo, G. and Rassendren, F.: P2X receptors: an emerging channel family. Eur. J. Neurosci., 8: 2221, 1996.
19. Fujii, K.: Evidence for adenosine triphosphate as an excitatory transmitter in guinea-pig, rabbit and pig urinary bladder. J. Physiol., 404: 39, 1988.
20. Palea, S., Corsi, M., Pietra, C., Artibani, W., Calpista, A., Gaviraghi, G. and Trist, D. G.: ADP-beta-S induces contraction of the human isolated bladder through a purinoceptor subtype different from P2X or P2Y. J. Pharm. Exp. Therap., 269: 193, 1994.
21. Eaton, A. C. and Bates, C. P.: An in vitro physiological study of normal and unstable human detrusor muscle. Br. J. Urol., 54: 653, 1982.
22. Saito, M., Kond, A., Kato, T. and Levin, R. M.: Response of isolated human neurogenic detrusor smooth muscle to intramural nerve stimulation. Br. J. Urol., 72: 723, 1993.
23. Luheshi, G. N. and Zar, M. A.: Presence of non-cholinergic transmission in isolated human bladder. J. Pharm. Pharmacol., 42: 223, 1990.
24. Sibley, G. N. A.: The physiological response of the detrusor muscle to experimental bladder outflow obstruction in the pig. Br. J. Urol., 60: 332, 1987.
25. Wu, C., Bayliss, M., Newgreen, D. and Fry, C. H.: A comparison of the mode of action of ATP and carbachol on isolated human detrusor smooth muscle. J. Urol., 162: 1840, 1999.
26. Hoyle, C. H., Chapple, C. and Burnstock, G.: Isolated human bladder: evidence for an adenine dinucleotideacting on P2X-purinoceptors and for purinergic transmission. Eur. J. Pharmacol., 174: 115, 1989.
27. 3+ on contractility and ecto-ATPase activity in the guinea-pig urinary bladder. Br. J. Pharmacol., 114: 632, 1995.