메뉴 건너뛰기




Volumn 47, Issue 7, 2013, Pages 926-934

Analysis of Sp transcription factors in the postmortem brain of chronic schizophrenia: A pilot study of relationship to negative symptoms

Author keywords

Cerebellum; Negative symptoms; Postmortem brain; Prefrontal cortex; Schizophrenia; Sp transcription factors

Indexed keywords

DOPAMINE 2 RECEPTOR; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TRANSCRIPTION FACTOR SP;

EID: 84877134014     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2013.03.004     Document Type: Article
Times cited : (38)

References (50)
  • 2
    • 3442876969 scopus 로고    scopus 로고
    • Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets
    • Andersen C.L., Jensen J.L., Orntoft T.F. Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Research 2004, 64:5245-5250.
    • (2004) Cancer Research , vol.64 , pp. 5245-5250
    • Andersen, C.L.1    Jensen, J.L.2    Orntoft, T.F.3
  • 3
    • 0029003189 scopus 로고
    • A longitudinal study of symptom dimensions in schizophrenia. Prediction and patterns of change
    • Arndt S., Andreasen N.C., Flaum M., Miller D., Nopoulos P. A longitudinal study of symptom dimensions in schizophrenia. Prediction and patterns of change. Archives of General Psychiatry 1995, 52:352-360.
    • (1995) Archives of General Psychiatry , vol.52 , pp. 352-360
    • Arndt, S.1    Andreasen, N.C.2    Flaum, M.3    Miller, D.4    Nopoulos, P.5
  • 4
    • 85015398777 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society: Series B 1995, 57:289-300.
    • (1995) Journal of the Royal Statistical Society: Series B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 5
    • 41049092301 scopus 로고    scopus 로고
    • Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2
    • e817
    • Ben-Shachar D., Karry R. Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2. PLoS One 2007, 2. e817.
    • (2007) PLoS One , pp. 2
    • Ben-Shachar, D.1    Karry, R.2
  • 6
    • 0034666043 scopus 로고    scopus 로고
    • Are schizophrenic and bipolar disorders related? A review of family and molecular studies
    • Berrettini W.H. Are schizophrenic and bipolar disorders related? A review of family and molecular studies. Biological Psychiatry 2000, 48:531-538.
    • (2000) Biological Psychiatry , vol.48 , pp. 531-538
    • Berrettini, W.H.1
  • 7
    • 85015382710 scopus 로고
    • The stability of symptoms and syndromes in chronic schizophrenic patients
    • Borde M., Davis E.J., Sharma L.N. The stability of symptoms and syndromes in chronic schizophrenic patients. Indian Journal of Psychiatry 1992, 34:133-139.
    • (1992) Indian Journal of Psychiatry , vol.34 , pp. 133-139
    • Borde, M.1    Davis, E.J.2    Sharma, L.N.3
  • 8
    • 0037201722 scopus 로고    scopus 로고
    • Regulation of the activity of Sp1-related transcription factors
    • Bouwman P., Philipsen S. Regulation of the activity of Sp1-related transcription factors. Molecular and Cellular Endocrinology 2002, 195:27-38.
    • (2002) Molecular and Cellular Endocrinology , vol.195 , pp. 27-38
    • Bouwman, P.1    Philipsen, S.2
  • 10
    • 38949183056 scopus 로고    scopus 로고
    • Prefrontal cortex function in nonpsychotic siblings of individuals with schizophrenia
    • Delawalla Z., Csernansky J.G., Barch D.M. Prefrontal cortex function in nonpsychotic siblings of individuals with schizophrenia. Biological Psychiatry 2008, 63:490-497.
    • (2008) Biological Psychiatry , vol.63 , pp. 490-497
    • Delawalla, Z.1    Csernansky, J.G.2    Barch, D.M.3
  • 11
    • 0036430378 scopus 로고    scopus 로고
    • State-dependent alterations in mitochondrial complex I activity in platelets: a potential peripheral marker for schizophrenia
    • Dror N., Klein E., Karry R., Sheinkman A., Kirsh Z., Mazor M., et al. State-dependent alterations in mitochondrial complex I activity in platelets: a potential peripheral marker for schizophrenia. Molecular Psychiatry 2002, 7:995-1001.
    • (2002) Molecular Psychiatry , vol.7 , pp. 995-1001
    • Dror, N.1    Klein, E.2    Karry, R.3    Sheinkman, A.4    Kirsh, Z.5    Mazor, M.6
  • 13
    • 65349191920 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia, revisited
    • Fatemi S.H., Folsom T.D. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophrenia Bulletin 2009, 35:528-548.
    • (2009) Schizophrenia Bulletin , vol.35 , pp. 528-548
    • Fatemi, S.H.1    Folsom, T.D.2
  • 16
    • 0030907389 scopus 로고    scopus 로고
    • Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility
    • Han I., Kudlow J.E. Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility. Molecular and Cellular Biology 1997, 17:2550-2558.
    • (1997) Molecular and Cellular Biology , vol.17 , pp. 2550-2558
    • Han, I.1    Kudlow, J.E.2
  • 17
    • 0037505200 scopus 로고    scopus 로고
    • The clinical global impression-schizophrenia scale: a simple instrument to measure the diversity of symptoms present in schizophrenia
    • Haro J.M., Kamath S.A., Ochoa S., Novick D., Rele K., Fargas A., et al. The clinical global impression-schizophrenia scale: a simple instrument to measure the diversity of symptoms present in schizophrenia. Acta Psychiatrica Scandinavica Supplementum 2003, 16-23.
    • (2003) Acta Psychiatrica Scandinavica Supplementum , pp. 16-23
    • Haro, J.M.1    Kamath, S.A.2    Ochoa, S.3    Novick, D.4    Rele, K.5    Fargas, A.6
  • 18
    • 2942534284 scopus 로고    scopus 로고
    • Cerebellar dysfunction in neuroleptic naive schizophrenia patients: clinical, cognitive, and neuroanatomic correlates of cerebellar neurologic signs
    • Ho B.C., Mola C., Andreasen N.C. Cerebellar dysfunction in neuroleptic naive schizophrenia patients: clinical, cognitive, and neuroanatomic correlates of cerebellar neurologic signs. Biological Psychiatry 2004, 55:1146-1153.
    • (2004) Biological Psychiatry , vol.55 , pp. 1146-1153
    • Ho, B.C.1    Mola, C.2    Andreasen, N.C.3
  • 19
    • 77953542391 scopus 로고    scopus 로고
    • Oxidative-stress-induced alterations in Sp factors mediate transcriptional regulation of the NR1 subunit in hippocampus during hypoxia
    • Hota S.K., Hota K.B., Prasad D., Ilavazhagan G., Singh S.B. Oxidative-stress-induced alterations in Sp factors mediate transcriptional regulation of the NR1 subunit in hippocampus during hypoxia. Free Radical Biology & Medicine 2010, 49:178-191.
    • (2010) Free Radical Biology & Medicine , vol.49 , pp. 178-191
    • Hota, S.K.1    Hota, K.B.2    Prasad, D.3    Ilavazhagan, G.4    Singh, S.B.5
  • 20
    • 77957932592 scopus 로고    scopus 로고
    • Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: Ser311Cys polymorphisms of the dopamine D2-receptor gene and schizophrenia
    • Itokawa M., Arinami T., Toru M. Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: Ser311Cys polymorphisms of the dopamine D2-receptor gene and schizophrenia. Journal of Pharmacological Sciences 2010, 114:1-5.
    • (2010) Journal of Pharmacological Sciences , vol.114 , pp. 1-5
    • Itokawa, M.1    Arinami, T.2    Toru, M.3
  • 21
    • 0032903301 scopus 로고    scopus 로고
    • The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia
    • Jentsch J.D., Roth R.H. The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia. Neuropsychopharmacology 1999, 20:201-225.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 201-225
    • Jentsch, J.D.1    Roth, R.H.2
  • 23
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay S.R., Fiszbein A., Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin 1987, 13:261-276.
    • (1987) Schizophrenia Bulletin , vol.13 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 25
    • 27744562656 scopus 로고    scopus 로고
    • Gene expression microarray studies in polygenic psychiatric disorders: applications and data analysis
    • Konradi C. Gene expression microarray studies in polygenic psychiatric disorders: applications and data analysis. Brain Research. Brain Research Reviews 2005, 50:142-155.
    • (2005) Brain Research. Brain Research Reviews , vol.50 , pp. 142-155
    • Konradi, C.1
  • 26
    • 0028323167 scopus 로고
    • Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
    • Krystal J.H., Karper L.P., Seibyl J.P., Freeman G.K., Delaney R., Bremner J.D., et al. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Archives of General Psychiatry 1994, 51:199-214.
    • (1994) Archives of General Psychiatry , vol.51 , pp. 199-214
    • Krystal, J.H.1    Karper, L.P.2    Seibyl, J.P.3    Freeman, G.K.4    Delaney, R.5    Bremner, J.D.6
  • 27
    • 10644259646 scopus 로고    scopus 로고
    • Effects of dopamine D2 receptor Ser311Cys polymorphism and clinical factors on risperidone efficacy for positive and negative symptoms and social function
    • Lane H.Y., Lee C.C., Chang Y.C., Lu C.T., Huang C.H., Chang W.H. Effects of dopamine D2 receptor Ser311Cys polymorphism and clinical factors on risperidone efficacy for positive and negative symptoms and social function. International Journal of Neuropsychopharmacology 2004, 7:461-470.
    • (2004) International Journal of Neuropsychopharmacology , vol.7 , pp. 461-470
    • Lane, H.Y.1    Lee, C.C.2    Chang, Y.C.3    Lu, C.T.4    Huang, C.H.5    Chang, W.H.6
  • 28
    • 81955167938 scopus 로고    scopus 로고
    • Better understanding of mechanisms of schizophrenia and bipolar disorder: from human gene expression profiles to mouse models
    • Lin C.Y., Sawa A., Jaaro-Peled H. Better understanding of mechanisms of schizophrenia and bipolar disorder: from human gene expression profiles to mouse models. Neurobiology of Disease 2011, 45:48-56.
    • (2011) Neurobiology of Disease , vol.45 , pp. 48-56
    • Lin, C.Y.1    Sawa, A.2    Jaaro-Peled, H.3
  • 29
    • 0038712731 scopus 로고    scopus 로고
    • Functional analysis of the rat N-methyl-d-aspartate receptor 2A promoter: multiple transcription starts points, positive regulation by Sp factors, and translational regulation
    • Liu A., Zhuang Z., Hoffman P.W., Bai G. Functional analysis of the rat N-methyl-d-aspartate receptor 2A promoter: multiple transcription starts points, positive regulation by Sp factors, and translational regulation. Journal of Biological Chemistry 2003, 278:26423-26434.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 26423-26434
    • Liu, A.1    Zhuang, Z.2    Hoffman, P.W.3    Bai, G.4
  • 30
    • 37149035534 scopus 로고    scopus 로고
    • The role of the cerebellum in schizophrenia: an update of clinical, cognitive, and functional evidences
    • Picard H., Amado I., Mouchet-Mages S., Olie J.P., Krebs M.O. The role of the cerebellum in schizophrenia: an update of clinical, cognitive, and functional evidences. Schizophrenia Bulletin 2008, 34:155-172.
    • (2008) Schizophrenia Bulletin , vol.34 , pp. 155-172
    • Picard, H.1    Amado, I.2    Mouchet-Mages, S.3    Olie, J.P.4    Krebs, M.O.5
  • 31
    • 80054864694 scopus 로고    scopus 로고
    • The transcription factor SP4 is reduced in postmortem cerebellum of bipolar disorder subjects: control by depolarization and lithium
    • Pinacho R., Villalmanzo N., Lalonde J., Haro J.M., Meana J.J., Gill G., et al. The transcription factor SP4 is reduced in postmortem cerebellum of bipolar disorder subjects: control by depolarization and lithium. Bipolar Disorder 2011, 13:474-485.
    • (2011) Bipolar Disorder , vol.13 , pp. 474-485
    • Pinacho, R.1    Villalmanzo, N.2    Lalonde, J.3    Haro, J.M.4    Meana, J.J.5    Gill, G.6
  • 34
    • 68349113702 scopus 로고    scopus 로고
    • Sp4-dependent repression of neurotrophin-3 limits dendritic branching
    • Ramos B., Valin A., Sun X., Gill G. Sp4-dependent repression of neurotrophin-3 limits dendritic branching. Molecular and Cellular Neuroscience 2009, 42:152-159.
    • (2009) Molecular and Cellular Neuroscience , vol.42 , pp. 152-159
    • Ramos, B.1    Valin, A.2    Sun, X.3    Gill, G.4
  • 35
    • 24144485818 scopus 로고    scopus 로고
    • Stability in schizophrenia symptoms over time: findings from the Mount Sinai Pilgrim Psychiatric Center Longitudinal Study
    • Reichenberg A., Rieckmann N., Harvey P.D. Stability in schizophrenia symptoms over time: findings from the Mount Sinai Pilgrim Psychiatric Center Longitudinal Study. Journal of Abnormal Psychology 2005, 114:363-372.
    • (2005) Journal of Abnormal Psychology , vol.114 , pp. 363-372
    • Reichenberg, A.1    Rieckmann, N.2    Harvey, P.D.3
  • 36
    • 0027999831 scopus 로고
    • Stability trends and longitudinal correlations of negative and positive syndromes within a three-year follow-up of initially hospitalized schizophrenics
    • Rey E.R., Bailer J., Brauer W., Handel M., Laubenstein D., Stein A. Stability trends and longitudinal correlations of negative and positive syndromes within a three-year follow-up of initially hospitalized schizophrenics. Acta Psychiatrica Scandinavica 1994, 90:405-412.
    • (1994) Acta Psychiatrica Scandinavica , vol.90 , pp. 405-412
    • Rey, E.R.1    Bailer, J.2    Brauer, W.3    Handel, M.4    Laubenstein, D.5    Stein, A.6
  • 37
    • 44349116762 scopus 로고    scopus 로고
    • Banco de tejidos neurológicos de Sant Joan de Déu-Serveis de Salut Mental para la investigación de las enfermendades mentales. La importancia de un programa de donación en vida
    • Roca M., Escanilla A., Monje A., Baño V., Planchat L., Costa J., et al. Banco de tejidos neurológicos de Sant Joan de Déu-Serveis de Salut Mental para la investigación de las enfermendades mentales. La importancia de un programa de donación en vida. Psiquiatría Biológica 2008, 15:73-79.
    • (2008) Psiquiatría Biológica , vol.15 , pp. 73-79
    • Roca, M.1    Escanilla, A.2    Monje, A.3    Baño, V.4    Planchat, L.5    Costa, J.6
  • 38
    • 0025031812 scopus 로고
    • No adjustments are needed for multiple comparisons
    • Rothman K.J. No adjustments are needed for multiple comparisons. Epidemiology 1990, 1:43-46.
    • (1990) Epidemiology , vol.1 , pp. 43-46
    • Rothman, K.J.1
  • 39
    • 16244405603 scopus 로고    scopus 로고
    • Mammalian SP/KLF transcription factors: bring in the family
    • Suske G., Bruford E., Philipsen S. Mammalian SP/KLF transcription factors: bring in the family. Genomics 2005, 85:551-556.
    • (2005) Genomics , vol.85 , pp. 551-556
    • Suske, G.1    Bruford, E.2    Philipsen, S.3
  • 40
    • 64749106515 scopus 로고    scopus 로고
    • Schizophrenia, " just the facts" 4. Clinical features and conceptualization
    • Tandon R., Nasrallah H.A., Keshavan M.S. Schizophrenia, " just the facts" 4. Clinical features and conceptualization. Schizophrenia Research 2009, 110:1-23.
    • (2009) Schizophrenia Research , vol.110 , pp. 1-23
    • Tandon, R.1    Nasrallah, H.A.2    Keshavan, M.S.3
  • 41
    • 84858752028 scopus 로고    scopus 로고
    • Elevated transcription factor specificity protein 1 in autistic brains alters the expression of autism candidate genes
    • Thanseem I., Anitha A., Nakamura K., Suda S., Iwata K., Matsuzaki H., et al. Elevated transcription factor specificity protein 1 in autistic brains alters the expression of autism candidate genes. Biological Psychiatry 2012, 71:410-418.
    • (2012) Biological Psychiatry , vol.71 , pp. 410-418
    • Thanseem, I.1    Anitha, A.2    Nakamura, K.3    Suda, S.4    Iwata, K.5    Matsuzaki, H.6
  • 43
    • 34848890053 scopus 로고    scopus 로고
    • Dopamine hypothesis of schizophrenia: making sense of it all
    • Toda M., Abi-Dargham A. Dopamine hypothesis of schizophrenia: making sense of it all. Current Psychiatry Reports 2007, 9:329-336.
    • (2007) Current Psychiatry Reports , vol.9 , pp. 329-336
    • Toda, M.1    Abi-Dargham, A.2
  • 44
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biology 2002, 3. RESEARCH0034.
    • (2002) Genome Biology , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6
  • 45
    • 0141450364 scopus 로고    scopus 로고
    • False discoveries and models for gene discovery
    • van den Oord E.J., Sullivan P.F. False discoveries and models for gene discovery. Trends in Genetics 2003, 19:537-542.
    • (2003) Trends in Genetics , vol.19 , pp. 537-542
    • van den Oord, E.J.1    Sullivan, P.F.2
  • 47
    • 0031750030 scopus 로고    scopus 로고
    • Sp family transcription factors regulate expression of rat D2 dopamine receptor gene
    • Yajima S., Lee S.H., Minowa T., Mouradian M.M. Sp family transcription factors regulate expression of rat D2 dopamine receptor gene. DNA and Cell Biology 1998, 17:471-479.
    • (1998) DNA and Cell Biology , vol.17 , pp. 471-479
    • Yajima, S.1    Lee, S.H.2    Minowa, T.3    Mouradian, M.M.4
  • 48
    • 79960878842 scopus 로고    scopus 로고
    • The role of the cerebellum in schizophrenia: from cognition to molecular pathways
    • Yeganeh-Doost P., Gruber O., Falkai P., Schmitt A. The role of the cerebellum in schizophrenia: from cognition to molecular pathways. Clinics (Sao Paulo) 2011, 66(Suppl. 1):71-77.
    • (2011) Clinics (Sao Paulo) , vol.66 , Issue.SUPPL. 1 , pp. 71-77
    • Yeganeh-Doost, P.1    Gruber, O.2    Falkai, P.3    Schmitt, A.4
  • 49
    • 16844371331 scopus 로고    scopus 로고
    • Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization
    • Zhou X., Long J.M., Geyer M.A., Masliah E., Kelsoe J.R., Wynshaw-Boris A., et al. Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization. Molecular Psychiatry 2005, 10:393-406.
    • (2005) Molecular Psychiatry , vol.10 , pp. 393-406
    • Zhou, X.1    Long, J.M.2    Geyer, M.A.3    Masliah, E.4    Kelsoe, J.R.5    Wynshaw-Boris, A.6
  • 50
    • 65249124607 scopus 로고    scopus 로고
    • Transcription factor SP4 is a susceptibility gene for bipolar disorder
    • e5196
    • Zhou X., Tang W., Greenwood T.A., Guo S., He L., Geyer M.A., et al. Transcription factor SP4 is a susceptibility gene for bipolar disorder. PLoS One 2009, 4(4). e5196.
    • (2009) PLoS One , vol.4 , Issue.4
    • Zhou, X.1    Tang, W.2    Greenwood, T.A.3    Guo, S.4    He, L.5    Geyer, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.