Re-analysis of bipolar disorder and schizophrenia gene expression complements the kraepelinian dichotomy

Advances in Experimental Medicine and Biology

Volumn 736, Issue , 2012, Pages 563-577

  Qian, Kui ^a   Di Lieto, Antonio ^b   Corander, Jukka ^b   Auvinen, Petri ^a   Greco, Dario ^c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA;

ALGORITHM; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC DATABASE; HUMAN; KRAEPELINIAN DICHOTOMY; MULTIGENE FAMILY; POSTTRANSCRIPTIONAL GENE SILENCING; PREDICTION; PREFRONTAL CORTEX; PRIORITY JOURNAL; RNA DEGRADATION; SCHIZOPHRENIA; UPREGULATION; VALIDITY;

BIPOLAR DISORDER; COMPUTATIONAL BIOLOGY; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POSTMORTEM CHANGES; PREFRONTAL CORTEX; REPRODUCIBILITY OF RESULTS; SCHIZOPHRENIA;

KRAEPELINIA;

EID: 84855973739     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-7210-1_33     Document Type: Article

References (64)

1. American Psychiatric Association Task Force on DSM-IV (2000) Diagnostic and statistical manual of mental disorders: DSM-IV-TR, 4th edn. American Psychiatric Association, Washington, pp xxxvii, 943
2. Consortium WTCC (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447(7145):661-678
3. Sullivan PF, Kendler KS, Neale MC (2003) Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry 60(12):1187-1192 (Pubitemid 37494071)
4. Craddock N, O'Donovan MC, Owen MJ (2006) Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophr Bull 32(1):9-16 (Pubitemid 43063811)
5. Consortium IS (2008) Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 455(7210):237-241
6. Lichtenstein P et al (2009) Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet 373(9659):234-239
7. Purcell SM et al (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460(7256):748-752
8. Stefansson H et al (2008) Large recurrent microdeletions associated with schizophrenia. Nature 455(7210):232-236
9. Hunsberger JG et al (2009) micrornas in mental health: from biological underpinnings to potential therapies. Neuromol Med 11(3):173-182
10. Burmeister M,McInnisMG, Zollner S (2008) Psychiatric genetics: progress amid controversy. Nat Rev Genet 9(7):527-540 (Pubitemid 351972757)
11. Mirnics K et al (2000) Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron 28(1):53-67
12. Ryan MM et al (2006) Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes. Mol Psychiatry 11(10):965-978 (Pubitemid 44470218)
13. Nakatani N et al (2006) Genome-wide expression analysis detects eight genes with robust alterations specific to bipolar I disorder: relevance to neuronal network perturbation. Hum Mol Genet 15(12):1949-1962 (Pubitemid 43983269)
14. Tkachev D et al (2007) Further evidence for altered myelin biosynthesis and glutamatergic dysfunction in schizophrenia. Int J Neuropsychopharmacol 10(4):557-563 (Pubitemid 46985260)
15. Benes FM et al (2005) The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia. Mol Psychiatry 11(3):241-251
16. Iwamoto K, Bundo M, Kato T (2005) Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by largescale DNA microarray analysis. Hum Mol Genet 14(2):241-253
17. Tkachev D et al (2003) Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 362(9386):798-805 (Pubitemid 37093922)
18. Iwamoto K et al (2004) Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders. Mol Psychiatry 9(4): 406-416 (Pubitemid 38534701)
19. Prabakaran S et al (2004) Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Mol Psychiatry 9(7):684-697, 643 (Pubitemid 38932173)
20. Hashimoto T et al (2008) Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia. Mol Psychiatry 13(2):147-161
21. Larsson O, Wennmalm K, Sandberg R (2006) Comparative microarray analysis. OMICS 10(3):381-397 (Pubitemid 44736322)
22. Greco D et al (2008) Physiology, pathology and relatedness of human tissues from gene expression meta-analysis. PLoS One 3(4):e1880
23. Parman C, Halling C (2009) affyQCReport: a package to generate QC reports for affymetrix array data
24. Bolstad BM et al (2003) A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19(2):185-193 (Pubitemid 36181903)
25. Irizarry RA et al (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4(2):249-264
26. Gautier L et al (2004) affy - analysis of Affymetrix genechip data at the probe level. Bioinformatics 20(3):307-315 (Pubitemid 38262761)
27. Goeman JJ et al (2004) A global test for groups of genes: testing association with a clinical outcome. Bioinformatics 20(1):93-99 (Pubitemid 38088346)
28. Smyth GK (2005) Limma: linearmodels for microarray data. In: Gentleman R, Carey V, Dudoit S, Irizarry R, Huber W (eds) Bioinformatics and computational biology solutions using R and bioconductor. New York: Springer, pp 397-420
29. Huang daW, Sherman BT, Lempicki RA (2009) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37(1):1-13
30. Huang da W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4(1):44-57
31. Zhang B, Kirov S, Snoddy J (2005) webgestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res 33(Web Server issue):W741-748 (Pubitemid 44530021)
32. Yeung KY, Bumgarner RE, Raftery AE (2005) Bayesian model averaging: development of an improved multi-class, gene selection and classification tool for microarray data. Bioinformatics 21(10):2394-2402 (Pubitemid 40731595)
33. Maglott D et al (2007) Entrez gene: gene-centered information at NCBI. Nucleic Acids Res 35(Database issue):D26-31 (Pubitemid 46056164)
34. Choi KH et al (2008) Putative psychosis genes in the prefrontal cortex: combined analysis of gene expression microarrays. BMC Psychiatry 8:87
35. Pedersen CB, Mortensen PB, Cantor-Graae E (2011) Do risk factors for schizophrenia predispose to emigration? Schizophr Res 127(1-3):229-234
36. Fatjo-Vilas M et al (2011) Dysbindin-1 gene contributes differentially to early- and adult-onset forms of functional psychosis. Am J Med Genet B Neuropsychiatr Genet 156(3):322-333
37. Gruber O et al (2011) A systematic experimental neuropsychological investigation of the functional integrity of working memory circuits in major depression. Eur Arch Psychiatry Clin Neurosci 261:179-184
38. McIntosh BJ et al (2011) Performance-based assessment of functional skills in severe mental illness: results of a large-scale study in China. J Psychiatr Res:45(8):1089-1094
39. Mueser KT et al (2010) Neurocognition and social skill in older persons with schizophrenia and major mood disorders: An analysis of gender and diagnosis effects. J Neurolinguistics 23(3):297-317
40. Pedersen CB, Mortensen PB, Cantor-Graae E Do risk factors for schizophrenia predispose to emigration? Schizophr Res 127(1-3):229-234
41. Hashimoto K, Sawa A, Iyo M(2007) Increased levels of glutamate in brains from patients with mood disorders. Biol Psychiatry 62(11):1310-1316 (Pubitemid 350060893)
42. Rollins B et al (2009) Mitochondrial variants in schizophrenia, bipolar disorder, and major depressive disorder. PLoS One 4(3):e4913
43. Nasrallah HA, Brecher M, Paulsson B (2006) Placebo-level incidence of extrapyramidal symptoms (EPS) with quetiapine in controlled studies of patients with bipolar mania. Bipolar Disord 8(5 Pt 1):467-474 (Pubitemid 44560220)
44. Lewis R, Bagnall AM, LeitnerM(2005) Sertindole for schizophrenia. Cochrane Database Syst Rev (3):CD001715. Review. PMID: 16034864 [PubMed - indexed for MEDLINE]
45. Thompson Ray M et al (2011) Decreased BDNF, trkb-TKC and GAD(67) mrna expression in the hippocampus of individuals with schizophrenia and mood disorders. J Psychiatry Neurosci 36(1):100048
46. Wang JF et al (2009) Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia. Bipolar Disord 11(5):523-529
47. Pounds SB (2006) Estimation and control of multiple testing error rates for microarray studies. Brief Bioinform 7(1):25-36 (Pubitemid 44404321)
48. Moreau MP et al (2011) Altered microrna expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorder. Biol Psychiatry 69(2):188-193
49. Kim AH et al (2010) microrna expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders. Schizophr Res 124(1-3):183-191
50. Dinan TG (2010) micrornas as a target for novel antipsychotics: a systematic review of an emerging field. Int J Neuropsychopharmacol 13(3):395-404
51. Gershon ES, Alliey-Rodriguez N, Liu C (2011) After GWAS: searching for genetic risk for Schizophrenia and bipolar disorder. Am J Psychiatry 168(3):253-256
52. Souza BR et al (2011) Downregulation of the camp/PKA pathway in PC12 cells overexpressing NCS-1. Cell Mol Neurobiol 31(1):135-143
53. Yuan P et al (2010) Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia. J Affect Disord 124(1-2):164-169
54. Yuan P et al Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia. J Affect Disord 124(1-2):164-169
55. Kakiuchi C et al (2007) Association analysis of ATF4 and ATF5, genes for interacting-proteins of DISC1, in bipolar disorder. Neurosci Lett 417(3):316-321 (Pubitemid 46589787)
56. Ubhi K, Price J (2005) Expression of POU-domain transcription factor, Oct-6, in schizophrenia, bipolar disorder and major depression. BMC Psychiatry 5:38
57. Iwayama Y et al (2010) Association analyses between brain-expressed fatty-acid binding protein (FABP) genes and schizophrenia and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 153B(2):484-493
58. Quinones MP, Kaddurah-Daouk R (2009) Metabolomics tools for identifying biomarkers for neuropsychiatric diseases. Neurobiol Dis 35(2):165-176
59. Adibhatla RM, Hatcher JF (2010) Lipid oxidation and peroxidation in CNS health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 12(1): 125-169
60. Shedden K et al (2008) Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med 14(8):822-827
61. van't Veer LJ, Bernards R (2008) Enabling personalized cancer medicine through analysis of gene-expression patterns. Nature 452(7187):564-570 (Pubitemid 351483370)
62. Lee SC et al (2009) Post-treatment tumor gene expression signatures are more predictive of treatment outcomes than baseline signatures in breast cancer. Pharmacogenet Genomics 19(11):833-842
63. Zaas AK et al (2010) Blood gene expression signatures predict invasive candidiasis. Sci Transl Med 2(21):21ra17
64. Morozova O, Hirst M, Marra MA (2009) Applications of new sequencing technologies for transcriptome analysis. Annu Rev Genomics Hum Genet 10:135-151