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Volumn 80, Issue 6, 2013, Pages 728-731

NADP+-dependent IDH1R132 mutation and its relevance for glioma patient survival

Author keywords

[No Author keywords available]

Indexed keywords

ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REACTIVE OXYGEN METABOLITE;

EID: 84877123057     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2013.02.022     Document Type: Article
Times cited : (23)

References (52)
  • 1
    • 53949091844 scopus 로고    scopus 로고
    • Brain tumor epidemiology: consensus from the brain tumor epidemiology consortium
    • Bondy M.L., Scheurer M.E., Malmer B., et al. Brain tumor epidemiology: consensus from the brain tumor epidemiology consortium. Cancer 2010, 113:1953-1968.
    • (2010) Cancer , vol.113 , pp. 1953-1968
    • Bondy, M.L.1    Scheurer, M.E.2    Malmer, B.3
  • 2
    • 84860312386 scopus 로고    scopus 로고
    • Recent advances in the molecular understanding of glioblastoma
    • Bleeker F.E., Molenaar R., Leenstra S. Recent advances in the molecular understanding of glioblastoma. J Neuro Oncol 2012, 108:11-27.
    • (2012) J Neuro Oncol , vol.108 , pp. 11-27
    • Bleeker, F.E.1    Molenaar, R.2    Leenstra, S.3
  • 3
    • 58349111311 scopus 로고    scopus 로고
    • IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors
    • Bleeker F.E., Lamba S., Leenstra S., et al. IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors. Hum Mutat 2009, 30:7-11.
    • (2009) Hum Mutat , vol.30 , pp. 7-11
    • Bleeker, F.E.1    Lamba, S.2    Leenstra, S.3
  • 5
    • 78149249554 scopus 로고    scopus 로고
    • IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
    • Houillier C., Wang X., Kaloshi G., et al. IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas. Neurology 2010, 75:1560-1566.
    • (2010) Neurology , vol.75 , pp. 1560-1566
    • Houillier, C.1    Wang, X.2    Kaloshi, G.3
  • 6
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • Yan H., Parsons D.W., Jin G., et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med 2009, 360:765-773.
    • (2009) N Engl J Med , vol.360 , pp. 765-773
    • Yan, H.1    Parsons, D.W.2    Jin, G.3
  • 7
    • 77954697566 scopus 로고    scopus 로고
    • Isocitrate dehydrogenase 1 and 2 mutations in cancer: altenations at a crossroads of cellular metabolism
    • Reitman Z.J., Yan H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: altenations at a crossroads of cellular metabolism. J Natl Cancer Inst 2010, 102:932-941.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 932-941
    • Reitman, Z.J.1    Yan, H.2
  • 8
    • 70149093912 scopus 로고    scopus 로고
    • Recurring mutations found by sequencing an acute myeloid leukemia genome
    • Mardis E.R., Ding L., Dooling D.J., et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 2010, 361:1058-1066.
    • (2010) N Engl J Med , vol.361 , pp. 1058-1066
    • Mardis, E.R.1    Ding, L.2    Dooling, D.J.3
  • 9
    • 77950968519 scopus 로고    scopus 로고
    • Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation
    • Chou H.A., Chen C.Y., Tang J.L., et al. Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation. Blood 2010, 115:2749-2754.
    • (2010) Blood , vol.115 , pp. 2749-2754
    • Chou, H.A.1    Chen, C.Y.2    Tang, J.L.3
  • 10
    • 77649305610 scopus 로고    scopus 로고
    • The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting α-ketoglutarate to 2-hydroxyglutarate
    • Ward P.S., Patel J., Wise D.R., et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting α-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 2010, 17:225-234.
    • (2010) Cancer Cell , vol.17 , pp. 225-234
    • Ward, P.S.1    Patel, J.2    Wise, D.R.3
  • 11
    • 79958822681 scopus 로고    scopus 로고
    • Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma
    • Atai N.A., Renkema-Mills N.A., Bosman J., et al. Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma. J Histochem Cytochem 2011, 59:489-503.
    • (2011) J Histochem Cytochem , vol.59 , pp. 489-503
    • Atai, N.A.1    Renkema-Mills, N.A.2    Bosman, J.3
  • 12
    • 84860378609 scopus 로고    scopus 로고
    • Rock C.O. Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation
    • Leonardi R., Subramanian C., Jackowski S. Rock C.O. Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation. J Biol Chem 2012, 287:14615-14620.
    • (2012) J Biol Chem , vol.287 , pp. 14615-14620
    • Leonardi, R.1    Subramanian, C.2    Jackowski, S.3
  • 13
    • 72049125350 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • Dang L., White D.W., Gross S., et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009, 462:739-744.
    • (2009) Nature , vol.462 , pp. 739-744
    • Dang, L.1    White, D.W.2    Gross, S.3
  • 14
    • 0141446035 scopus 로고    scopus 로고
    • Reduced nicotinamide adenine dinucleotide phosphate and the higher incidence of pollution-induced liver cancer in female flounder
    • Koehler A., Van Noorden C.J.F. Reduced nicotinamide adenine dinucleotide phosphate and the higher incidence of pollution-induced liver cancer in female flounder. Environ Toxicol Chem 2003, 22:2703-2710.
    • (2003) Environ Toxicol Chem , vol.22 , pp. 2703-2710
    • Koehler, A.1    Van Noorden, C.J.F.2
  • 15
    • 77952311188 scopus 로고    scopus 로고
    • Thioredoxin and thioredoxin reductase: current research with special reference to human disease
    • Holmgren A., Lu J. Thioredoxin and thioredoxin reductase: current research with special reference to human disease. Biochem Biophys Res Commun 2010, 396:120-124.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 120-124
    • Holmgren, A.1    Lu, J.2
  • 16
    • 0033613855 scopus 로고    scopus 로고
    • Enhanced glutathione levels and oxidoresistance mediated by increased glucose-6-phosphate dehydrogenase expression
    • Salvemini F., Franze A., Iervolino A., Filosa S., Salzano S., Ursini M.V. Enhanced glutathione levels and oxidoresistance mediated by increased glucose-6-phosphate dehydrogenase expression. J Biol Chem 1999, 274:2750-2757.
    • (1999) J Biol Chem , vol.274 , pp. 2750-2757
    • Salvemini, F.1    Franze, A.2    Iervolino, A.3    Filosa, S.4    Salzano, S.5    Ursini, M.V.6
  • 17
    • 0022743296 scopus 로고
    • A quantitative histochemical study of NADPH-ferrihemoprotein reductase activity
    • Van Noorden C.J.F., Butcher R.G. A quantitative histochemical study of NADPH-ferrihemoprotein reductase activity. Histochem J 1986, 18:364-370.
    • (1986) Histochem J , vol.18 , pp. 364-370
    • Van Noorden, C.J.F.1    Butcher, R.G.2
  • 18
    • 34748858784 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis: impact on cancer therapy
    • Ozben T. Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci 2007, 96:2181-2196.
    • (2007) J Pharm Sci , vol.96 , pp. 2181-2196
    • Ozben, T.1
  • 19
    • 70449711757 scopus 로고    scopus 로고
    • Genetic alterations and signaling pathways in the evolution of gliomas
    • Ohgaki H., Kleihues P. Genetic alterations and signaling pathways in the evolution of gliomas. Cancer Sci 2009, 100:2235-2241.
    • (2009) Cancer Sci , vol.100 , pp. 2235-2241
    • Ohgaki, H.1    Kleihues, P.2
  • 20
    • 57349166553 scopus 로고    scopus 로고
    • Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review
    • Aghili M., Zahedi F., Rafiee E. Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review. J Neuro Oncol 2009, 91:233-236.
    • (2009) J Neuro Oncol , vol.91 , pp. 233-236
    • Aghili, M.1    Zahedi, F.2    Rafiee, E.3
  • 21
    • 79955547561 scopus 로고    scopus 로고
    • The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
    • Chowdhury R., Kheng Yeoh K., Tian Y., et al. The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO J 2011, 12:463-469.
    • (2011) EMBO J , vol.12 , pp. 463-469
    • Chowdhury, R.1    Kheng Yeoh, K.2    Tian, Y.3
  • 22
    • 78651463452 scopus 로고    scopus 로고
    • Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of a-ketoglutarate-dependent dioxygenases
    • Xu W., Yang H., Liu Y., et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of a-ketoglutarate-dependent dioxygenases. Cancer Cell 2011, 19:17-30.
    • (2011) Cancer Cell , vol.19 , pp. 17-30
    • Xu, W.1    Yang, H.2    Liu, Y.3
  • 23
    • 85027932695 scopus 로고    scopus 로고
    • Altered cancer cell metabolism in gliomas with mutant IDH1 and IDH2
    • Borodovsky A., Seltzer M.J., Riggins G.J. Altered cancer cell metabolism in gliomas with mutant IDH1 and IDH2. Curr Opin Oncol 2012, 24:83-89.
    • (2012) Curr Opin Oncol , vol.24 , pp. 83-89
    • Borodovsky, A.1    Seltzer, M.J.2    Riggins, G.J.3
  • 24
    • 79952741730 scopus 로고    scopus 로고
    • Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
    • Proc Natl Acad Sci USA 2011;108:3270-5.
    • Reitman ZJ, Jin GL, Karoly ED, et al. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc Natl Acad Sci USA 2011;108:3270-5.
    • Reitman, Z.J.1    Jin, G.L.2    Karoly, E.D.3
  • 25
    • 84870538996 scopus 로고    scopus 로고
    • R132H/WT mutation induces genome-wide alterations in DNA methylation
    • R132H/WT mutation induces genome-wide alterations in DNA methylation. Genome Res 2012, 22:2339-2355.
    • (2012) Genome Res , vol.22 , pp. 2339-2355
    • Duncan, C.G.1    Barwick, B.G.2    Jin, G.3
  • 27
    • 64849087954 scopus 로고    scopus 로고
    • Puzzling patterns of predisposition
    • Pollard P.J., Ratcliffe P.J. Puzzling patterns of predisposition. Science 2009, 324:192-194.
    • (2009) Science , vol.324 , pp. 192-194
    • Pollard, P.J.1    Ratcliffe, P.J.2
  • 28
    • 60849139085 scopus 로고    scopus 로고
    • Metabolic enzymes as oncogenes or tumor suppressors
    • Thompson C.B. Metabolic enzymes as oncogenes or tumor suppressors. N Engl J Med 2009, 360:813-815.
    • (2009) N Engl J Med , vol.360 , pp. 813-815
    • Thompson, C.B.1
  • 29
    • 77954736390 scopus 로고    scopus 로고
    • Oncometabolite? IDH1 discoveries raise possibility of new metabolism targets in brain cancers and leukemia
    • Garber K. Oncometabolite? IDH1 discoveries raise possibility of new metabolism targets in brain cancers and leukemia. J Natl Cancer Inst 2010, 102:926-928.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 926-928
    • Garber, K.1
  • 30
    • 70349653793 scopus 로고    scopus 로고
    • IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas
    • Nobusawa S., Watanabe T., Kleihues P., Ohgaki H. IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas. Clin Cancer Res 2009, 15:6002-6007.
    • (2009) Clin Cancer Res , vol.15 , pp. 6002-6007
    • Nobusawa, S.1    Watanabe, T.2    Kleihues, P.3    Ohgaki, H.4
  • 33
    • 79952313734 scopus 로고    scopus 로고
    • Isocitrate dehyrdogenase mutations may be a protective mechanism in glioma patients
    • Zhu J., Zuo J., Xu Q., Wang X., Wang Z., Zhou D. Isocitrate dehyrdogenase mutations may be a protective mechanism in glioma patients. Med Hypotheses 2011, 76:602-603.
    • (2011) Med Hypotheses , vol.76 , pp. 602-603
    • Zhu, J.1    Zuo, J.2    Xu, Q.3    Wang, X.4    Wang, Z.5    Zhou, D.6
  • 34
    • 77955508065 scopus 로고    scopus 로고
    • Glioma-derived mutations in IDH: from mechanism to potential therapy
    • Fu Y., Huang R., Du J., Yang R., An N., Liang A. Glioma-derived mutations in IDH: from mechanism to potential therapy. Biochem Biophys Res Commun 2010, 397:127-130.
    • (2010) Biochem Biophys Res Commun , vol.397 , pp. 127-130
    • Fu, Y.1    Huang, R.2    Du, J.3    Yang, R.4    An, N.5    Liang, A.6
  • 35
    • 79959696548 scopus 로고    scopus 로고
    • Glioma-derived mutations in isocitrate dehydrogenase 2 beneficial to traditional chemotherapy
    • Fu Y., Huang R., Zheng Y., Zhang Z., Liang A. Glioma-derived mutations in isocitrate dehydrogenase 2 beneficial to traditional chemotherapy. Biochem Biophys Res Commun 2011, 410:218-223.
    • (2011) Biochem Biophys Res Commun , vol.410 , pp. 218-223
    • Fu, Y.1    Huang, R.2    Zheng, Y.3    Zhang, Z.4    Liang, A.5
  • 36
    • 84864367362 scopus 로고    scopus 로고
    • MGMT promoter hypermethylation and its associations with genetic alterations in a series of 350 brain tumors
    • Mellai M., Monzeglio O., Piazzi A., et al. MGMT promoter hypermethylation and its associations with genetic alterations in a series of 350 brain tumors. J Neuro Oncol 2012, 107:617-631.
    • (2012) J Neuro Oncol , vol.107 , pp. 617-631
    • Mellai, M.1    Monzeglio, O.2    Piazzi, A.3
  • 37
    • 84860790212 scopus 로고    scopus 로고
    • Review: molecular pathology in adult high-grade gliomas: from molecular diagnostics to target therapies
    • Masui K., Cloughesy T.F., Mischel P.S. Review: molecular pathology in adult high-grade gliomas: from molecular diagnostics to target therapies. Neuropathol Appl Neurobiol 2012, 38:271-291.
    • (2012) Neuropathol Appl Neurobiol , vol.38 , pp. 271-291
    • Masui, K.1    Cloughesy, T.F.2    Mischel, P.S.3
  • 38
    • 51649117107 scopus 로고    scopus 로고
    • Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
    • Hegi M.E., Liu L., Herman J.G., et al. Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol 2008, 26:4189-4199.
    • (2008) J Clin Oncol , vol.26 , pp. 4189-4199
    • Hegi, M.E.1    Liu, L.2    Herman, J.G.3
  • 39
    • 0031053586 scopus 로고    scopus 로고
    • Regulation of neuronal survival by the serine-threonine protein kinase Akt
    • Dudek H., Datta S.R., Franke T.F., et al. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 1997, 275:661-665.
    • (1997) Science , vol.275 , pp. 661-665
    • Dudek, H.1    Datta, S.R.2    Franke, T.F.3
  • 40
    • 79953287708 scopus 로고    scopus 로고
    • IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo
    • Bralten L.B., Kloosterhof N.K., Balvers R., et al. IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo. Ann Neurol 2011, 69:455-463.
    • (2011) Ann Neurol , vol.69 , pp. 455-463
    • Bralten, L.B.1    Kloosterhof, N.K.2    Balvers, R.3
  • 41
    • 84858796262 scopus 로고    scopus 로고
    • IDH mutation impairs histone demethylation and results in a block to cell differentiation
    • Lu C., Ward P.S., Kapoor G.S., et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 2012, 483:474-478.
    • (2012) Nature , vol.483 , pp. 474-478
    • Lu, C.1    Ward, P.S.2    Kapoor, G.S.3
  • 42
    • 84856466311 scopus 로고    scopus 로고
    • IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma
    • Song Tao Q., Lei Y., Si G., et al. IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma. Cancer Sci 2012, 103:269-273.
    • (2012) Cancer Sci , vol.103 , pp. 269-273
    • Song Tao, Q.1    Lei, Y.2    Si, G.3
  • 43
    • 84863225078 scopus 로고    scopus 로고
    • MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 and IDH2 mutations
    • Mulholland S., Pearson D.M., Hamoudi R.A., et al. MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 and IDH2 mutations. Int J Cancer 2012, 131:1104-1113.
    • (2012) Int J Cancer , vol.131 , pp. 1104-1113
    • Mulholland, S.1    Pearson, D.M.2    Hamoudi, R.A.3
  • 44
    • 73349121355 scopus 로고    scopus 로고
    • MGMT promotor methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC brain tumor group study 26951
    • Van den Bent M.J., Dubbink H.J., Sanson M., et al. MGMT promotor methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC brain tumor group study 26951. J Clin Oncol 2009, 27:5881-5886.
    • (2009) J Clin Oncol , vol.27 , pp. 5881-5886
    • Van den Bent, M.J.1    Dubbink, H.J.2    Sanson, M.3
  • 45
    • 75849146316 scopus 로고    scopus 로고
    • MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma
    • Rivera A.L., Pelloski C.E., Gilbert M., et al. MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma. Neuro Oncol 2010, 12:116-121.
    • (2010) Neuro Oncol , vol.12 , pp. 116-121
    • Rivera, A.L.1    Pelloski, C.E.2    Gilbert, M.3
  • 46
    • 70249097408 scopus 로고    scopus 로고
    • Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
    • Sanson M., Marie Y., Paris S., et al. Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol 2009, 27:4150-4154.
    • (2009) J Clin Oncol , vol.27 , pp. 4150-4154
    • Sanson, M.1    Marie, Y.2    Paris, S.3
  • 47
    • 73349134695 scopus 로고    scopus 로고
    • NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine and temozolomide
    • Wick W., Hartmann C., Engel C., et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine and temozolomide. J Clin Oncol 2009, 27:5874-5880.
    • (2009) J Clin Oncol , vol.27 , pp. 5874-5880
    • Wick, W.1    Hartmann, C.2    Engel, C.3
  • 48
    • 0017384020 scopus 로고
    • +-specific isocitrate dehydrogenase by oxalacetate and glyoxylate I. Oxalomalate formation and stability, and nature of the enzyme inhibition
    • +-specific isocitrate dehydrogenase by oxalacetate and glyoxylate I. Oxalomalate formation and stability, and nature of the enzyme inhibition. Biochem Biophys Acta 1977, 483:24-34.
    • (1977) Biochem Biophys Acta , vol.483 , pp. 24-34
    • Johanson, R.A.1    Reeves, H.C.2
  • 50
    • 79952697258 scopus 로고    scopus 로고
    • Glioma cells showing IDH1 mutation cannot be propagated in standard cell culture conditions
    • Piaskowski S., Bienkoswki M., Stoczynska-Fidelus E., et al. Glioma cells showing IDH1 mutation cannot be propagated in standard cell culture conditions. Br J Cancer 2011, 104:968-970.
    • (2011) Br J Cancer , vol.104 , pp. 968-970
    • Piaskowski, S.1    Bienkoswki, M.2    Stoczynska-Fidelus, E.3
  • 51
    • 84859553853 scopus 로고    scopus 로고
    • An in vivo patient-derived model of endogenous IDH1-mutant glioma
    • Artee Luchman H., Stechishin O.D., Ha Dang N., et al. An in vivo patient-derived model of endogenous IDH1-mutant glioma. Neuro Oncol 2012, 14:184-191.
    • (2012) Neuro Oncol , vol.14 , pp. 184-191
    • Artee Luchman, H.1    Stechishin, O.D.2    Ha Dang, N.3
  • 52
    • 78549283855 scopus 로고    scopus 로고
    • Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1
    • Cancer Res 2010;70:8981-7.
    • Seltzer MJ, Bennett BD, Joshi AD, et al. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Res 2010;70:8981-7.
    • Seltzer, M.J.1    Bennett, B.D.2    Joshi, A.D.3


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