-
1
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell P.C. The clonal evolution of tumor cell populations. Science 194 (1976) 23-28
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
3
-
-
0000886345
-
Nesso fisio-pathologico tra la struttura dei nei materni e la genesi di alcuni tumori maligni
-
Durante F. Nesso fisio-pathologico tra la struttura dei nei materni e la genesi di alcuni tumori maligni. Arch Memor Observ Chir Pract 11 (1874) 217-226
-
(1874)
Arch Memor Observ Chir Pract
, vol.11
, pp. 217-226
-
-
Durante, F.1
-
4
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F., and Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 414 (2001) 105-111
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
5
-
-
34250190230
-
Cancer initiation and progression: involvement of stem cells and the microenvironment
-
Tysnes B.B., and Bjerkvig R. Cancer initiation and progression: involvement of stem cells and the microenvironment. Biochim Biophys Acta 1775 (2007) 283-297
-
(2007)
Biochim Biophys Acta
, vol.1775
, pp. 283-297
-
-
Tysnes, B.B.1
Bjerkvig, R.2
-
7
-
-
1542374198
-
Problems of somatic mutation and cancer
-
Frank S.A., and Nowak M.A. Problems of somatic mutation and cancer. Bioessays 26 (2004) 291-299
-
(2004)
Bioessays
, vol.26
, pp. 291-299
-
-
Frank, S.A.1
Nowak, M.A.2
-
8
-
-
84965187257
-
The age distribution of cancer and a multi-stage theory of carcinogenesis
-
Armitage P., and Doll R. The age distribution of cancer and a multi-stage theory of carcinogenesis. Br J Cancer 8 (1954) 1-12
-
(1954)
Br J Cancer
, vol.8
, pp. 1-12
-
-
Armitage, P.1
Doll, R.2
-
9
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
10
-
-
0027254069
-
How many mutations are required for tumorigenesis? Implications from human cancer data
-
Renan M.J. How many mutations are required for tumorigenesis? Implications from human cancer data. Mol Carcinog 7 (1993) 139-146
-
(1993)
Mol Carcinog
, vol.7
, pp. 139-146
-
-
Renan, M.J.1
-
11
-
-
0345059767
-
Applying the principles of stem-cell biology to cancer
-
Pardal R., Clarke M.F., and Morrison S.J. Applying the principles of stem-cell biology to cancer. Nat Rev Cancer 3 (2003) 895-902
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 895-902
-
-
Pardal, R.1
Clarke, M.F.2
Morrison, S.J.3
-
12
-
-
0030988803
-
Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo
-
Blair A., Hogge D.E., Ailles L.E., Lansdorp P.M., and Sutherland H.J. Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo. Blood 89 (1997) 3104-3112
-
(1997)
Blood
, vol.89
, pp. 3104-3112
-
-
Blair, A.1
Hogge, D.E.2
Ailles, L.E.3
Lansdorp, P.M.4
Sutherland, H.J.5
-
13
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D., and Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3 (1997) 730-737
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
14
-
-
15944364734
-
Identification of human chronic myelogenous leukemia progenitor cells with hemangioblastic characteristics
-
Fang B., Zheng C., Liao L., Han Q., Sun Z., Jiang X., et al. Identification of human chronic myelogenous leukemia progenitor cells with hemangioblastic characteristics. Blood 105 (2005) 2733-2740
-
(2005)
Blood
, vol.105
, pp. 2733-2740
-
-
Fang, B.1
Zheng, C.2
Liao, L.3
Han, Q.4
Sun, Z.5
Jiang, X.6
-
15
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot T., Sirard C., Vormoor J., Murdoch B., Hoang T., Caceres-Cortes J., et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367 (1994) 645-648
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
-
16
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J., and Clarke M.F. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100 (2003) 3983-3988
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
17
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli R., Binda E., Orfanelli U., Cipelletti B., Gritti A., De Vitis S., et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64 (2004) 7011-7021
-
(2004)
Cancer Res
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
De Vitis, S.6
-
18
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh S.K., Hawkins C., Clarke I.D., Squire J.A., Bayani J., Hide T., et al. Identification of human brain tumour initiating cells. Nature 432 (2004) 396-401
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
-
19
-
-
33644825465
-
Stem-like cells in bone sarcomas: implications for tumorigenesis
-
Gibbs C.P., Kukekov V.G., Reith J.D., Tchigrinova O., Suslov O.N., Scott E.W., et al. Stem-like cells in bone sarcomas: implications for tumorigenesis. Neoplasia 7 (2005) 967-976
-
(2005)
Neoplasia
, vol.7
, pp. 967-976
-
-
Gibbs, C.P.1
Kukekov, V.G.2
Reith, J.D.3
Tchigrinova, O.4
Suslov, O.N.5
Scott, E.W.6
-
20
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim C.F., Jackson E.L., Woolfenden A.E., Lawrence S., Babar I., Vogel S., et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121 (2005) 823-835
-
(2005)
Cell
, vol.121
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
Lawrence, S.4
Babar, I.5
Vogel, S.6
-
21
-
-
27144557960
-
tumorigenic subpopulation with stem cell properties in melanomas
-
Fang D., Nguyen T.K., Leishear K., Finko R., Kulp A.N., Hotz S., et al. tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 65 (2005) 9328-9337
-
(2005)
Cancer Res
, vol.65
, pp. 9328-9337
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
Finko, R.4
Kulp, A.N.5
Hotz, S.6
-
22
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
Collins A.T., Berry P.A., Hyde C., Stower M.J., and Maitland N.J. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65 (2005) 10946-10951
-
(2005)
Cancer Res
, vol.65
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
23
-
-
85047690508
-
Opinion: the origin of the cancer stem cell: current controversies and new insights
-
Bjerkvig R., Tysnes B.B., Aboody K.S., Najbauer J., and Terzis A.J. Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat Rev Cancer 5 (2005) 899-904
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 899-904
-
-
Bjerkvig, R.1
Tysnes, B.B.2
Aboody, K.S.3
Najbauer, J.4
Terzis, A.J.5
-
24
-
-
0038819885
-
Stem-cell hierarchy in skin cancer
-
Perez-Losada J., and Balmain A. Stem-cell hierarchy in skin cancer. Nat Rev Cancer 3 (2003) 434-443
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 434-443
-
-
Perez-Losada, J.1
Balmain, A.2
-
25
-
-
7744236303
-
Cancer stem cell biology: from leukemia to solid tumors
-
Jordan C.T. Cancer stem cell biology: from leukemia to solid tumors. Curr Opin Cell Biol 16 (2004) 708-712
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 708-712
-
-
Jordan, C.T.1
-
26
-
-
34249332411
-
Beier CP. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
-
Beier D., Hau P., Proescholdt M., Lohmeier A., Wischhusen J., Oefner P.J., et al. Beier CP. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 67 (2007) 4010-4015
-
(2007)
Cancer Res
, vol.67
, pp. 4010-4015
-
-
Beier, D.1
Hau, P.2
Proescholdt, M.3
Lohmeier, A.4
Wischhusen, J.5
Oefner, P.J.6
-
27
-
-
0346100567
-
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
-
Cozzio A., Passegue E., Ayton P.M., Karsunky H., Cleary M.L., and Weissman I.L. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev 17 (2003) 3029-3035
-
(2003)
Genes Dev
, vol.17
, pp. 3029-3035
-
-
Cozzio, A.1
Passegue, E.2
Ayton, P.M.3
Karsunky, H.4
Cleary, M.L.5
Weissman, I.L.6
-
28
-
-
10944235028
-
Chronic versus acute myelogenous leukemia: a question of self-renewal
-
Jamieson C.H., Weissman I.L., and Passegue E. Chronic versus acute myelogenous leukemia: a question of self-renewal. Cancer Cell 6 (2004) 531-533
-
(2004)
Cancer Cell
, vol.6
, pp. 531-533
-
-
Jamieson, C.H.1
Weissman, I.L.2
Passegue, E.3
-
29
-
-
0141483064
-
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
-
Passegue E., Jamieson C.H., Ailles L.E., and Weissman I.L. Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?. Proc Natl Acad Sci USA 100 Suppl. 1 (2003) 11842-11849
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.SUPPL. 1
, pp. 11842-11849
-
-
Passegue, E.1
Jamieson, C.H.2
Ailles, L.E.3
Weissman, I.L.4
-
30
-
-
38349075007
-
CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells
-
Wang J., Sakariassen P.O., Tsinkalovsky O., Immervoll H., Boe S.O., Svendsen A., et al. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int J Cancer 122 (2008) 761-768
-
(2008)
Int J Cancer
, vol.122
, pp. 761-768
-
-
Wang, J.1
Sakariassen, P.O.2
Tsinkalovsky, O.3
Immervoll, H.4
Boe, S.O.5
Svendsen, A.6
-
31
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana E., Shackleton M., Sabel M.S., Fullen D.R., Johnson T.M., and Morrison S.J. Efficient tumour formation by single human melanoma cells. Nature 456 (2008) 593-598
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
32
-
-
33644559031
-
Identifying cancer stem cells in solid tumors: case not proven
-
[discussion 0]
-
Hill R.P. Identifying cancer stem cells in solid tumors: case not proven. Cancer Res 66 (2006) 1891-1895 [discussion 0]
-
(2006)
Cancer Res
, vol.66
, pp. 1891-1895
-
-
Hill, R.P.1
-
33
-
-
34547113747
-
Tumor growth need not be driven by rare cancer stem cells
-
Kelly P.N., Dakic A., Adams J.M., Nutt S.L., and Strasser A. Tumor growth need not be driven by rare cancer stem cells. Science (2007) 317-337
-
(2007)
Science
, pp. 317-337
-
-
Kelly, P.N.1
Dakic, A.2
Adams, J.M.3
Nutt, S.L.4
Strasser, A.5
-
34
-
-
52049117849
-
A stochastic model for cancer stem cell origin in metastatic colon cancer
-
Odoux C., Fohrer H., Hoppo T., Guzik L., Stolz D.B., Lewis D.W., et al. A stochastic model for cancer stem cell origin in metastatic colon cancer. Cancer Res 68 (2008) 6932-6941
-
(2008)
Cancer Res
, vol.68
, pp. 6932-6941
-
-
Odoux, C.1
Fohrer, H.2
Hoppo, T.3
Guzik, L.4
Stolz, D.B.5
Lewis, D.W.6
-
36
-
-
70549093230
-
-
Warburg O, Wind E, Negelein E. On the metabolism of tumours in the body. In: The Metabolism of Tumours: Investigations from the Kaiser Wilhelm Institute for Biology, Berlin-Dahlen, London: Constable&Co., Ltd; 1930
-
Warburg O, Wind E, Negelein E. On the metabolism of tumours in the body. In: The Metabolism of Tumours: Investigations from the Kaiser Wilhelm Institute for Biology, Berlin-Dahlen, London: Constable&Co., Ltd; 1930
-
-
-
-
37
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby R.A., and Gillies R.J. Why do cancers have high aerobic glycolysis?. Nat Rev Cancer 4 (2004) 891-899
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
38
-
-
2542634131
-
Hypoxia increases heparanase-dependent tumor cell invasion, which can be inhibited by antiheparanase antibodies
-
He X., Brenchley P.E., Jayson G.C., Hampson L., Davies J., and Hampson I.N. Hypoxia increases heparanase-dependent tumor cell invasion, which can be inhibited by antiheparanase antibodies. Cancer Res 64 (2004) 3928-3933
-
(2004)
Cancer Res
, vol.64
, pp. 3928-3933
-
-
He, X.1
Brenchley, P.E.2
Jayson, G.C.3
Hampson, L.4
Davies, J.5
Hampson, I.N.6
-
39
-
-
0037144460
-
Oxygen-mediated regulation of tumor cell invasiveness. Involvement of a nitric oxide signaling pathway
-
Postovit L.M., Adams M.A., Lash G.E., Heaton J.P., and Graham C.H. Oxygen-mediated regulation of tumor cell invasiveness. Involvement of a nitric oxide signaling pathway. J Biol Chem 277 (2002) 35730-35737
-
(2002)
J Biol Chem
, vol.277
, pp. 35730-35737
-
-
Postovit, L.M.1
Adams, M.A.2
Lash, G.E.3
Heaton, J.P.4
Graham, C.H.5
-
40
-
-
0344825132
-
Nitric oxide-mediated regulation of hypoxia-induced B16F10 melanoma metastasis
-
Postovit L.M., Adams M.A., Lash G.E., Heaton J.P., and Graham C.H. Nitric oxide-mediated regulation of hypoxia-induced B16F10 melanoma metastasis. Int J Cancer 108 (2004) 47-53
-
(2004)
Int J Cancer
, vol.108
, pp. 47-53
-
-
Postovit, L.M.1
Adams, M.A.2
Lash, G.E.3
Heaton, J.P.4
Graham, C.H.5
-
41
-
-
0027443181
-
The role of hypoxia in the maintenance of hematopoietic stem cells
-
Cipolleschi M.G., Dello Sbarba P., and Olivotto M. The role of hypoxia in the maintenance of hematopoietic stem cells. Blood 82 (1993) 2031-2037
-
(1993)
Blood
, vol.82
, pp. 2031-2037
-
-
Cipolleschi, M.G.1
Dello Sbarba, P.2
Olivotto, M.3
-
42
-
-
37449021071
-
Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche
-
Kubota Y., Takubo K., and Suda T. Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche. Biochem Biophys Res Commun 9 (2008) 335-366
-
(2008)
Biochem Biophys Res Commun
, vol.9
, pp. 335-366
-
-
Kubota, Y.1
Takubo, K.2
Suda, T.3
-
43
-
-
64249118309
-
Low oxygen concentration as a general physiologic regulator of erythropoiesis beyond the EPO-related downstream tuning and a tool for the optimization of red blood cell production ex vivo
-
Vlaski M., Lafarge X., Chevaleyre J., Duchez P., Boiron J.M., and Ivanovic Z. Low oxygen concentration as a general physiologic regulator of erythropoiesis beyond the EPO-related downstream tuning and a tool for the optimization of red blood cell production ex vivo. Exp Hematol 37 (2009) 573-584
-
(2009)
Exp Hematol
, vol.37
, pp. 573-584
-
-
Vlaski, M.1
Lafarge, X.2
Chevaleyre, J.3
Duchez, P.4
Boiron, J.M.5
Ivanovic, Z.6
-
44
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K., Hirao A., Arai F., Takubo K., Matsuoka S., Miyamoto K., et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 12 (2006) 446-451
-
(2006)
Nat Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
-
45
-
-
0035799605
-
Cell culture. progenitor cells from human brain after death
-
Palmer T.D., Schwartz P.H., Taupin P., Kaspar B., Stein S.A., and Gage F.H. Cell culture. progenitor cells from human brain after death. Nature 411 (2001) 42-43
-
(2001)
Nature
, vol.411
, pp. 42-43
-
-
Palmer, T.D.1
Schwartz, P.H.2
Taupin, P.3
Kaspar, B.4
Stein, S.A.5
Gage, F.H.6
-
46
-
-
54249151684
-
Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction
-
Das B., Tsuchida R., Malkin D., Koren G., Baruchel S., and Yeger H. Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction. Stem Cells 26 (2008) 1818-1830
-
(2008)
Stem Cells
, vol.26
, pp. 1818-1830
-
-
Das, B.1
Tsuchida, R.2
Malkin, D.3
Koren, G.4
Baruchel, S.5
Yeger, H.6
-
47
-
-
48649096658
-
Neural stem cell targeting of glioma is dependent on phosphoinositide 3-kinase signaling
-
Kendall S.E., Najbauer J., Johnston H.F., Metz M.Z., Li S., Bowers M., et al. Neural stem cell targeting of glioma is dependent on phosphoinositide 3-kinase signaling. Stem Cells 26 (2008) 1575-1586
-
(2008)
Stem Cells
, vol.26
, pp. 1575-1586
-
-
Kendall, S.E.1
Najbauer, J.2
Johnston, H.F.3
Metz, M.Z.4
Li, S.5
Bowers, M.6
-
48
-
-
60849117508
-
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
Bleau A.M., Hambardzumyan D., Ozawa T., Fomchenko E.I., Huse J.T., Brennan C.W., et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 4 (2009) 226-235
-
(2009)
Cell Stem Cell
, vol.4
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
Fomchenko, E.I.4
Huse, J.T.5
Brennan, C.W.6
-
49
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto K., Araki K.Y., Naka K., Arai F., Takubo K., Yamazaki S., et al. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 1 (2007) 101-112
-
(2007)
Cell Stem Cell
, vol.1
, pp. 101-112
-
-
Miyamoto, K.1
Araki, K.Y.2
Naka, K.3
Arai, F.4
Takubo, K.5
Yamazaki, S.6
-
50
-
-
34248359065
-
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
-
Parmar K., Mauch P., Vergilio J.A., Sackstein R., and Down J.D. Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc Natl Acad Sci USA 104 (2007) 5431-5436
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5431-5436
-
-
Parmar, K.1
Mauch, P.2
Vergilio, J.A.3
Sackstein, R.4
Down, J.D.5
-
51
-
-
67449092765
-
Cancer stem cells and their niche
-
Iwasaki H., and Suda T. Cancer stem cells and their niche. Cancer Sci 100 (2009) 1166-1172
-
(2009)
Cancer Sci
, vol.100
, pp. 1166-1172
-
-
Iwasaki, H.1
Suda, T.2
-
52
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
Elstrom R.L., Bauer D.E., Buzzai M., Karnauskas R., Harris M.H., Plas D.R., et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 64 (2004) 3892-3899
-
(2004)
Cancer Res
, vol.64
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
Karnauskas, R.4
Harris, M.H.5
Plas, D.R.6
-
53
-
-
60549111398
-
Is Akt the "Warburg kinase"? Akt-energy metabolism interactions and oncogenesis
-
Robey R.B., and Hay N. Is Akt the "Warburg kinase"? Akt-energy metabolism interactions and oncogenesis. Semin Cancer Biol 19 (2009) 25-31
-
(2009)
Semin Cancer Biol
, vol.19
, pp. 25-31
-
-
Robey, R.B.1
Hay, N.2
-
54
-
-
0041920901
-
TSC2 regulates VEGF through mTOR-dependent and -independent pathways
-
Brugarolas J.B., Vazquez F., Reddy A., Sellers W.R., and Kaelin Jr. W.G. TSC2 regulates VEGF through mTOR-dependent and -independent pathways. Cancer Cell 4 (2003) 147-158
-
(2003)
Cancer Cell
, vol.4
, pp. 147-158
-
-
Brugarolas, J.B.1
Vazquez, F.2
Reddy, A.3
Sellers, W.R.4
Kaelin Jr., W.G.5
-
55
-
-
56849118516
-
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis
-
Nogueira V., Park Y., Chen C.C., Xu P.Z., Chen M.L., Tonic I., et al. Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis. Cancer Cell 14 (2008) 458-470
-
(2008)
Cancer Cell
, vol.14
, pp. 458-470
-
-
Nogueira, V.1
Park, Y.2
Chen, C.C.3
Xu, P.Z.4
Chen, M.L.5
Tonic, I.6
-
56
-
-
0021978223
-
Tumor angiogenesis
-
Folkman J. Tumor angiogenesis. Adv Cancer Res 43 (1985) 175-203
-
(1985)
Adv Cancer Res
, vol.43
, pp. 175-203
-
-
Folkman, J.1
-
57
-
-
0022123620
-
Toward an understanding of angiogenesis: search and discovery
-
Folkman J. Toward an understanding of angiogenesis: search and discovery. Perspect Biol Med 29 (1985) 10-36
-
(1985)
Perspect Biol Med
, vol.29
, pp. 10-36
-
-
Folkman, J.1
-
58
-
-
85013312416
-
Tumor angiogenesis: therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 285 (1971) 1182-1186
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
59
-
-
36148937125
-
Tumour vascularization: sprouting angiogenesis and beyond
-
Hillen F., and Griffioen A.W. Tumour vascularization: sprouting angiogenesis and beyond. Cancer Metastasis Rev 26 (2007) 489-502
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 489-502
-
-
Hillen, F.1
Griffioen, A.W.2
-
60
-
-
4644304024
-
Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option
-
Leenders W.P., Kusters B., Verrijp K., Maass C., Wesseling P., Heerschap A., et al. Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option. Clin Cancer Res 10 (2004) 6222-6230
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6222-6230
-
-
Leenders, W.P.1
Kusters, B.2
Verrijp, K.3
Maass, C.4
Wesseling, P.5
Heerschap, A.6
-
61
-
-
0037102369
-
ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
-
Wedge S.R., Ogilvie D.J., Dukes M., Kendrew J., Chester R., Jackson J.A., et al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Research 62 (2002) 4645-4655
-
(2002)
Cancer Research
, vol.62
, pp. 4645-4655
-
-
Wedge, S.R.1
Ogilvie, D.J.2
Dukes, M.3
Kendrew, J.4
Chester, R.5
Jackson, J.A.6
-
62
-
-
34447121919
-
Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapy
-
Dickson P.V., Hamner J.B., Sims T.L., Fraga C.H., Ng C.Y., Rajasekeran S., et al. Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapy. Clin Cancer Res 13 (2007) 3942-3950
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3942-3950
-
-
Dickson, P.V.1
Hamner, J.B.2
Sims, T.L.3
Fraga, C.H.4
Ng, C.Y.5
Rajasekeran, S.6
-
63
-
-
58149456505
-
Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumab plus irinotecan
-
Zuniga R.M., Torcuator R., Jain R., Anderson J., Doyle T., Ellika S., et al. Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumab plus irinotecan. J Neurooncol 91 (2009) 329-336
-
(2009)
J Neurooncol
, vol.91
, pp. 329-336
-
-
Zuniga, R.M.1
Torcuator, R.2
Jain, R.3
Anderson, J.4
Doyle, T.5
Ellika, S.6
-
64
-
-
33750814849
-
Angiogenesis-independent tumor growth mediated by stem-like cancer cells
-
Sakariassen P.O., Prestegarden L., Wang J., Skaftnesmo K.O., Mahesparan R., Molthoff C., et al. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci USA 103 (2006) 16466-16471
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16466-16471
-
-
Sakariassen, P.O.1
Prestegarden, L.2
Wang, J.3
Skaftnesmo, K.O.4
Mahesparan, R.5
Molthoff, C.6
-
65
-
-
53849135949
-
Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics
-
Thorsen F., Jirak D., Wang J., Sykova E., Bjerkvig R., Enger P.O., et al. Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics. NMR Biomed 21 (2008) 830-838
-
(2008)
NMR Biomed
, vol.21
, pp. 830-838
-
-
Thorsen, F.1
Jirak, D.2
Wang, J.3
Sykova, E.4
Bjerkvig, R.5
Enger, P.O.6
-
66
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C., Poppleton H., Kocak M., Hogg T.L., Fuller C., Hamner B., et al. A perivascular niche for brain tumor stem cells. Cancer Cell 11 (2007) 69-82
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
-
67
-
-
59949083263
-
Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
-
Kreisl T.N., Kim L., Moore K., Duic P., Royce C., Stroud I., et al. Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J Clin Oncol 27 (2009) 740-745
-
(2009)
J Clin Oncol
, vol.27
, pp. 740-745
-
-
Kreisl, T.N.1
Kim, L.2
Moore, K.3
Duic, P.4
Royce, C.5
Stroud, I.6
-
68
-
-
65249185501
-
Bevacizumab and chemotherapy for recurrent glioblastoma: a single-institution experience
-
Nghiemphu P.L., Liu W., Lee Y., Than T., Graham C., Lai A., et al. Bevacizumab and chemotherapy for recurrent glioblastoma: a single-institution experience. Neurology 72 (2009) 1217-1222
-
(2009)
Neurology
, vol.72
, pp. 1217-1222
-
-
Nghiemphu, P.L.1
Liu, W.2
Lee, Y.3
Than, T.4
Graham, C.5
Lai, A.6
|