Striatal glutamate degenerates thalamic neurons

Journal of Neuropathology and Experimental Neurology

Volumn 72, Issue 4, 2013, Pages 286-297

  Morales, Ingrid ^a,b   Yanos, Catalina ^a   Rodriguez Sabate, Clara ^b   Sanchez, Alberto ^a   Rodriguez, Manuel ^a,b  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Astrocyte; Excitotoxicity; Glutamate; Self induced glutamate accumulation; Striatum; Thalamus

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; GLUTAMIC ACID; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; AMINO ACID RECEPTOR STIMULATING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BIOACCUMULATION; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; EXCITOTOXICITY; GLIOSIS; MALE; MYELINATED NERVE; NERVE CELL; NERVE CELL DEGENERATION; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; RAT; THALAMUS; ANIMAL; DRUG EFFECT; METABOLISM; NERVE DEGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; CORPUS STRIATUM; EXCITATORY AMINO ACID AGONISTS; GLUTAMIC ACID; MALE; NERVE DEGENERATION; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; THALAMUS;

MLCS; MLOWN;

EID: 84877108086     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e31828a80ee     Document Type: Article

References (59)

1. Albin RL, Reiner A, Anderson KD, et al. Preferential loss of striatoexternal pallidal projection neurons in presymptomatic Huntington's disease. Ann Neurol 1992;31:425-30
2. Douaud G, Behrens TE, Poupon C, et al. In vivo evidence for the selective subcortical degeneration in Huntington's disease. Neuroimage 2009;46:958-66
3. Kassubek J, Juengling FD, Ecker D, et al. Thalamic atrophy in Huntington's disease co-varies with cognitive performance: A morphometric MRI analysis. Cereb Cortex 2005;15:846-53
4. Meshul CK, Emre N, Nakamura CM, et al. Time-dependent changes in striatal glutamate synapses following a 6-hydroxydopamine lesion. Neuroscience 1999;88:1-16
5. Marti M, Sbrenna S, Fuxe K, et al. Increased responsivity of glutamate release from the substantia nigra pars reticulata to striatal NMDA receptor blockade in a model of Parkinson's disease. A dual probe microdialysis study in hemiparkinsonian rats. Eur J Neurosci 2000;12:1848-50
6. During MJ, Ryder KM, Spencer DD. Hippocampal GABA transporter function in temporal-lobe epilepsy. Nature 1995;376:174-77
7. Obrenovitch TP, Richards DA. Extracellular neurotransmitter changes in cerebral ischaemia. Cerebrovasc Brain Metab Rev 1995;7:1-54
8. Jenner P, Olanow CW. Understanding cell death in Parkinson's disease. Ann Neurol 1998e;44:S72-84
9. Olanow CW, Tatton WG. Etiology and pathogenesis of Parkinson's disease. Annu Rev Neurosci 1999;22:123-44
10. Rodriguez MC, Obeso JA, Olanow CW. Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: A target for neuroprotection. Ann Neurol 1998;44:S175-88
11. Obrenovitch TP, Urenjak J. Altered glutamatergic transmission in neurological disorders: From high extracellular glutamate to excessive synaptic efficacy. Prog Neurobiol 1997;51:39-87
12. Bezzi P, Carmignoto G, Pasti L, et al. Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature 1998;391:281-85
13. Morales I, Fuentes A, Gonzalez-Hernandez T, et al. Osmosensitive response of glutamate in the substantia nigra. Exp Neurol 2009;220: 335-40
14. Rodriguez Diaz M, Alonso TJ, Perdomo Diaz J, et al. Glial regulation of nonsynaptic extracellular glutamate in the substantia nigra. Glia 2005;49:134-42
15. de Groot J, Sontheimer H. Glutamate and the biology of gliomas. Glia 2011;59:1181-89
16. Sofroniew MV, Vinters HV. Astrocytes: Biology and pathology. Acta Neuropathol 2010;119:7-35
17. Halliday GM, Stevens CH. Glia: Initiators and progressors of pathology in Parkinson's disease. Mov Disord 2011;26:6-17
18. McGeer PL, McGeer EG. Glial reactions in Parkinson's disease. Mov Disord 2008;23:474-83
19. Raivich G, Bohatschek M, Kloss CU, et al. Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function. Brain Res Brain Res Rev 1999;30:77-105
20. Streit WJ, Walter SA, Pennell NA. Reactive microgliosis. Prog Neurobiol 1999;57:563-81
21. Hazell AS. Excitotoxic mechanisms in stroke: An update of concepts and treatment strategies. Neurochem Int 2007;50:941-53
22. McCarty MF. Down-regulation of microglial activation may represent a practical strategy for combating neurodegenerative disorders. Med Hypotheses 2006;67:251-69
23. Rappold PM, Tieu K. Astrocytes and therapeutics for Parkinson's disease. Neurotherapeutics 2010;7:413-23
24. Perry VH, Bell MD, Brown HC, et al. Inflammation in the nervous system. Curr Opin Neurobiol 1995;5:636-41
25. Vesce S, Rossi D, Brambilla L, et al. Glutamate release from astrocytes in physiological conditions and in neurodegenerative disorders characterized by neuroinflammation. Int Rev Neurobiol 2007;82:57-71
26. Bush TG, Puvanachandra N, Horner CH, et al. Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scarforming, reactive astrocytes in adult transgenic mice. Neuron 1999;23: 297-308
27. Rothstein JD, Dykes-Hoberg M, Pardo CA, et al. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 1996;16:675-86
28. Swanson RA, Ying W, Kauppinen TM. Astrocyte influences on ischemic neuronal death. Curr Mol Med 2004;4:193-205
29. Morales I, Rodriguez M. Self-induced accumulation of glutamate in striatal astrocytes and basal ganglia excitotoxicity. Glia 2012;60:1481-94
30. Garcia Dopico J, Perdomo Diaz J, Alonso TJ, et al. Extracellular taurine in the substantia nigra: Taurine-glutamate interaction. J Neurosci Res 2004;76:528-38
31. Dopico JG, Gonzalez-Hernandez T, Perez IM, et al. Glycine release in the substantia nigra: Interaction with glutamate and GABA. Neuropharmacology 2006;50:548-57
32. Obeso JA, Rodriguez-Oroz MC, Goetz CG, et al. Missing pieces in the Parkinson's disease puzzle. Nat Med 2010;16:653-61
33. Rodriguez M, Morales I, Gomez I, et al. Heterogeneous dopamine neurochemistry in the striatum: The fountain-drain matrix. J Pharmacol Exp Ther 2006;319:1-13
34. Morales I, Dopico JG, Sabate M, et al. Substantia nigra osmoregulation: Taurine and ATP involvement. Am J Physiol Cell Physiol 2007;292: C1934-41
35. Morales I, Fuentes A, Ballaz S, et al. Striatal interaction among dopamine, glutamate and ascorbate. Neuropharmacology 2012;63:1308-14
36. Schmued L, Bowyer J, Cozart M, et al. Introducing Black-Gold II, a highly soluble gold phosphate complex with several unique advantages for the histochemical localization of myelin. Brain Res 2008;1229: 210-17
37. Xiang Z, Nesterov EE, Skoch J, et al. Detection of myelination using a novel histological probe. J Histochem Cytochem 2005;53:1511-16
38. Matute C, Domercq M, Sanchez-Gomez MV. Glutamate-mediated glial injury: Mechanisms and clinical importance. Glia 2006;53:212-24
39. Oka A, Belliveau MJ, Rosenberg PA, et al. Vulnerability of oligodendroglia to glutamate: Pharmacology, mechanisms, and prevention. J Neurosci 1993;13:1441-53
40. Bakiri Y, Burzomato V, Frugier G, et al. Glutamatergic signaling in the brain's white matter. Neuroscience 2009;158:266-74
41. Karadottir R, Attwell D. Neurotransmitter receptors in the life and death of oligodendrocytes. Neuroscience 2007;145:1426-38
42. Matute C, Alberdi E, Domercq M, et al. Excitotoxic damage to white matter. J Anat 2007;210:693-702
43. Foran E, Trotti D. Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis. Antioxid Redox Signal 2009;11:1587-602
44. Danbolt NC. Glutamate uptake. Prog Neurobiol 2001;65:1-105
45. Robinson MB. The family of sodium-dependent glutamate transporters: A focus on the GLT-1/EAAT2 subtype. Neurochem Int 1998; 33:479-91
46. Ortinski PI, Dong J, Mungenast A, et al. Selective induction of astrocytic gliosis generates deficits in neuronal inhibition. Nat Neurosci 2010;13: 584-91
47. Mates JM, Segura JA, Campos-Sandoval JA, et al. Glutamine homeostasis and mitochondrial dynamics. Int J Biochem Cell Biol 2009;41:2051-61
48. Albrecht J, Sonnewald U, Waagepetersen HS, et al. Glutamine in the central nervous system: Function and dysfunction. Front Biosci 2007;12: 332-43
49. Hourani BT, Hamlin EM, Reynolds TB. Cerebrospinal fluid glutamine as a measure of hepatic encephalopathy. Arch Intern Med 1971;127: 1033-36
50. Lemberg A, Fernandez MA. Hepatic encephalopathy, ammonia, glutamate, glutamine and oxidative stress. Ann Hepatol 2009;8:95-102
51. Xu J, Peng H, Kang N, et al. Glutamate-induced exocytosis of glutamate from astrocytes. J Biol Chem 2007;282:24185-97
52. Del Arco A, Segovia G, Fuxe K, et al. Changes in dialysate concentrations of glutamate and GABA in the brain: An index of volume transmission mediated actions? J Neurochem 2003;85:23-33
53. Shinohara K, Honma S, Katsuno Y, et al. Circadian release of excitatory amino acids in the suprachiasmatic nucleus culture is Ca(2+)-independent. Neurosci Res 2000;36:245-50
54. Keefe KA, Sved AF, Zigmond MJ, et al. Stress-induced dopamine release in the neostriatum: Evaluation of the role of action potentials in nigrostriatal dopamine neurons or local initiation by endogenous excitatory amino acids. J Neurochem 1993;61:1943-52
55. Lowy MT, Gault L, Yamamoto BK. Adrenalectomy attenuates stress-induced elevations in extracellular glutamate concentrations in the hippocampus. J Neurochem 1993;61:1957-60
56. Saulskaya N, Marsden CA. Extracellular glutamate in the nucleus accumbens during a conditioned emotional response in the rat. Brain Res 1995;698:114-20
57. Tucci S, Rada P, Hernandez L. Role of glutamate in the amygdala and lateral hypothalamus in conditioned taste aversion. Brain Res 1998; 813:44-49
58. Bezzi P, Gundersen V, Galbete JL, et al. Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate. Nat Neurosci 2004;7:613-20
59. Takeuchi H, Jin S, Wang J, et al. Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner. J Biol Chem 2006;281:21362-68 Tecnología