Deletion polymorphism of Disc1 is common to all 129 mouse substrains: Implications for gene-targeting studies of brain function

Genetics

Volumn 173, Issue 4, 2006, Pages 2407-2410

  Clapcote, Steven J ^a   Roder, John C ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DISRUPTED IN SCHIZOPHRENIA 1 GENE; DNA POLYMORPHISM; EMBRYONIC STEM CELL; GENE; GENE DELETION; GENE TARGETING; GENOTYPE; MUTATION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; BRAIN; EMBRYO; GENE TARGETING; HUMANS; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; POLYMORPHISM, GENETIC; SEQUENCE DELETION; SPECIES SPECIFICITY; STEM CELLS;

EID: 33747813488     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.106.060749     Document Type: Article

References (22)

1. BECK, J. A., S. LLOYD, M. HAFEZPARAST, M. LENNON-PIERCE, J.T. EPPIG et al., 2000 Genealogies of mouse inbred strains. Nat. Genet. 24: 23-25.
2. BJORKLUND, M., I. SIVERINA, T. HEIKKINEN, H. TANILA, J. SALLINEN et al., 2001 Spatial working memory improvement by an alpha2-adrenoceptor agonist dexmedetomidine is not mediated through alpha2C-adrenoceptor. Prog. Neuropsychopharmacol. Biol. Psychiatry 25: 1539-1554.
3. CALLICOTT, J. H., R. E. STRAUB, L. PEZAWAS, M. F. EGAN, V. S. MATTAY et al., 2005 Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc. Natl. Acad. Sci. USA 102: 8627-8632.
4. CANNON, T. D., W. HENNAH, T. G. M. VAN ERP, P. M. THOMPSON, J. LONNQVIST et al., 2005 Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Arch. Gen. Psychiatry 62: 1205-1213.
5. DELLER, T., M. KORTE, S. CHABANIS, A. DRAKEW, H. SCHWEGLER et al., 2003 Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proc. Natl. Acad. Sci. USA 100: 10494-10499.
6. FESTING, M. F. W., E. M. SIMPSON, M. T. DAVISSON and L. E. MOBRAATEN, 1999 Revised nomenclature for strain 129 mice. Mamm. Genome 10: 836.
7. HODGKINSON, C. A., D. GOLDMAN, J. JAEGER, S. PERSAUD, J. M. KANE et al., 2004 Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am. J. Hum. Genet. 75: 862-872.
8. HUANG, T. T., M. NAEEMUDDIN, S. ELCHURI, M. YAMAGUCHI, H. M. KOZY et al., 2006 Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxidase dismutase. Hum. Mol. Genet. 15: 1187-1194.
9. Jackson Laboratory, 2001 New 129 nomenclature - revised. JAX Bulletin, No. 1 (http://jaxmice.jax.org/info/bulletin/bulletin01.html). The Jackson Laboratory, Bar Harbor, ME.
10. KAMIYA, A., K. KUBO, T. TOMODA, M. TAKAKI, R. YOUN et al., 2005 A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat. Cell Biol. 7: 1067-1078.
11. KOIKE, H., P. A. ARGUELLO, M. KVAJO, M. KARAYIORGOU and J. A. GOGOS, 2006 Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice. Proc. Natl. Acad. Sci. USA 103: 3693-3697.
12. MILLAR, J. K., J. C. WILSON-ANNAN, S. ANDERSON, S. CHRISTIE, M. S. TAYLOR et al., 2000 Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum. Mol. Genet. 9: 1415-1423.
13. MILLAR, J. K., R. JAMES, N. J. BRANDON and P. A. THOMSON, 2004 DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric disease. Ann. Med. 36: 1-12.
14. MILLAR, J. K., B. S. PICKARD, S. MACKIE, R. JAMES, S. CHRISTIE et al., 2005 DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 310: 1187-1190.
15. MOUSE GENOME DATABASE, 2006 ES cell line name and strain of origin. Mouse Genome Informatics (ftp://ftp.informatics.jax.org/pub/datasets/es_cell_lines. html). The Jackson Laboratory, Bar Harbor, ME.
16. PORTEOUS, D. J., and J. K. MILLAR, 2006 Disrupted in schizophrenia 1: building brains and memories. Trends Mol. Med. 12: 255-261.
17. SACHS, N. A., A. SAWA, S. E. HOLMES, C. A. ROSS, L. E. DELISI et al., 2005 A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Mol. Psychiatry 10: 758-764.
18. SECHLER, J. M. G., J. C. YIP and A. S. ROSENBERG, 1997 Genetic variation among 129 substrains: practical consequences. J. Immunol. 159: 5766-5768.
19. SIMPSON, E. M., C. C. LINDER, E. E. SARGENT, M. T. DAVISSON, L. E. MOBRAATEN et al., 1997 Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice. Nat. Genet. 16: 19-27.
20. SPECHT, C. G., and R. SCHOEPFER, 2001 Deletion of the alpha-synuclein locus in a sub-population of C57BL/6J inbred mice. BMC Neurosci. 2: 11.
21. THREADGILL, D. W., D. YEE, A. MATIN, J. H. NADEAU and T. MAGNUSON, 1997 Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain. Mamm. Genome 8: 390-393.
22. ZHANG, F., J. SARGINSON, C. CROMBIE, N. WALKER, D. ST. CLAIR et al., 2006 Genetic association between schizophrenia and the DISC1 gene in the Scottish population. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B: 155-159.