Development of a fluorescence-based HIV-1 integrase DNA binding assay for identification of novel HIV-1 integrase inhibitors

Antiviral Research

Volumn 98, Issue 3, 2013, Pages 441-448

  Han, Ying Shan ^a   Xiao, Wei Lie ^b   Quashie, Peter K ^a   Mesplède, Thibault ^a   Xu, Hongtao ^a   Deprez, Eric ^c   Delelis, Olivier ^c   Pu, Jian Xin ^b   Sun, Han Dong ^b   Wainberg, Mark A ^a  

^a MCGILL UNIVERSITY   (Canada)

^b KUNMING INSTITUTE OF BOTANY   (China)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Fluorescent assay; HIV 1 integrase inhibitors; Integrase DNA binding

Indexed keywords

FZ 41; HD 51; HD 547; INTEGRASE; INTEGRASE INHIBITOR; NIGRANOIC ACID; RHODAMINE; UNCLASSIFIED DRUG; VIRUS DNA;

ARTICLE; CONTROLLED STUDY; DRUG DNA BINDING; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; VIRUS REPLICATION; WILD TYPE;

BINDING, COMPETITIVE; DNA, VIRAL; FLUORESCENCE; FLUORESCENT DYES; HIGH-THROUGHPUT SCREENING ASSAYS; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV LONG TERMINAL REPEAT; HIV-1; PROTEIN BINDING; RECOMBINANT PROTEINS; SCHISANDRACEAE; SENSITIVITY AND SPECIFICITY; SESQUITERPENES; TRITERPENES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84877088089     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.04.001     Document Type: Article

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