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Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors
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Longitudinal analysis of raltegravir susceptibility and integrase replication capacity of HIV type 1 during virologic failure
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Kobayashi M., Nakahara K., Seki T., Miki S., Kawauchi S., Suyama A., Wakasa-Morimoto C., Kodama M., Endoh T., Oosugi E., Matsushita Y., Murai H., Fujishita T., Yoshinaga T., Garvey E., Foster S., Underwood M., Johns B., Sato A., Fujiwara T. Selection of diverse and clinically relevant integrase inhibitor-resistant HIV type 1 mutants. Antiviral Res. 2008, 80:213-222.
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