Glycogen synthase kinase-3beta affects size of dentate gyrus and species-typical behavioral tasks in transgenic and knockout mice

Behavioural Brain Research

Volumn 248, Issue , 2013, Pages 46-50

  Kondratiuk, Ilona ^a,b   Devijver, Herman ^b   Lechat, Benoit ^b   Van Leuven, Fred ^b   Kaczmarek, Leszek ^a   Filipkowski, Robert K ^c  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY OF FINANCE AND MANAGEMENT   (Poland)

Author keywords

Adult neurogenesis; Dentate gyrus; GSK 3beta knockout; GSK 3beta overexpression; Hippocampal tasks; Rodent specific behaviors

Indexed keywords

DOUBLECORTIN; GLYCOGEN SYNTHASE KINASE 3BETA; ISOPROTEIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BRAIN SIZE; BURYING; CELL COUNT; CELL DIFFERENTIATION; CONTROLLED STUDY; DENTATE GYRUS; DIGGING; HIPPOCAMPUS; KNOCKOUT MOUSE; MARBLE BURYING; MENTAL PERFORMANCE; MOUSE; NERVE CELL; NERVE CELL GROWTH; NESTING; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BEHAVIOR, ANIMAL; DENTATE GYRUS; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUROGENESIS; NEURONS; SIGNAL TRANSDUCTION;

EID: 84877058507     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2013.03.045     Document Type: Article

References (35)

1. Kaidanovich-Beilin O., Lipina T.V., Takao K., van Eede M., Hattori S., Laliberte C., et al. Abnormalities in brain structure and behavior in GSK-3alpha mutant mice. Molecular Brain 2009, 2:35.
2. Kim W.Y., Snider W.D. Functions of GSK-3 signaling in development of the nervous system. Frontiers in Molecular Neuroscience 2011, 4:44.
3. Kim W.Y., Wang X., Wu Y., Doble B.W., Patel S., Woodgett J.R., et al. GSK-3 is a master regulator of neural progenitor homeostasis. Nature Neuroscience 2009, 12:1390-1397.
4. Li Y.C., Gao W.J. GSK-3beta activity and hyperdopamine-dependent behaviors. Neuroscience and Biobehavioral Reviews 2011, 35:645-654.
5. Valvezan A.J., Klein P.S. GSK-3 and Wnt signaling in neurogenesis and bipolar disorder. Frontiers in Molecular Neuroscience 2012, 5:1.
6. Muyllaert D., Kremer A., Jaworski T., Borghgraef P., Devijver H., Croes S., et al. Glycogen synthase kinase-3beta, or a link between amyloid and tau pathology?. Genes, Brain, and Behavior 2008, 7(Suppl. 1):57-66.
7. Sheline Y.I., Sanghavi M., Mintun M.A., Gado M.H. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. Journal of Neuroscience 1999, 19:5034-5043.
8. Szamosi A., Kelemen O., Keri S. Hippocampal volume and the AKT signaling system in first-episode schizophrenia. Journal of Psychiatric Research 2012, 46:279-284.
9. Clelland C.D., Choi M., Romberg C., Clemenson G.D., Fragniere A., Tyers P., et al. A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 2009, 325:210-213.
10. Sahay A., Scobie K.N., Hill A.S., O'Carroll C.M., Kheirbek M.A., Burghardt N.S., et al. Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature 2011, 472:466-470.
11. Eisch A.J., Petrik D. Depression and hippocampal neurogenesis: a road to remission. Science 2012, 338:72-75.
12. Jayatissa M.N., Henningsen K., West M.J., Wiborg O. Decreased cell proliferation in the dentate gyrus does not associate with development of anhedonic-like symptoms in rats. Brain Research 2009, 1290:133-141.
13. Oomen C.A., Soeters H., Audureau N., Vermunt L., van Hasselt F.N., Manders E.M., et al. Early maternal deprivation affects dentate gyrus structure and emotional learning in adult female rats. Psychopharmacology (Berl) 2011, 214:249-260.
14. Oomen C.A., Soeters H., Audureau N., Vermunt L., van Hasselt F.N., Manders E.M., et al. Severe early life stress hampers spatial learning and neurogenesis, but improves hippocampal synaptic plasticity and emotional learning under high-stress conditions in adulthood. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 2010, 30:6635-6645.
15. Schmitz C., Rhodes M.E., Bludau M., Kaplan S., Ong P., Ueffing I., et al. Depression: reduced number of granule cells in the hippocampus of female, but not male, rats due to prenatal restraint stress. Molecular Psychiatry 2002, 7:810-813.
16. Spittaels K., Van den Haute C., Van Dorpe J., Terwel D., Vandezande K., Lasrado R., et al. Neonatal neuronal overexpression of glycogen synthase kinase-3 beta reduces brain size in transgenic mice. Neuroscience 2002, 113:797-808.
17. Prickaerts J., Moechars D., Cryns K., Lenaerts I., van Craenendonck H., Goris I., et al. Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania. Journal of Neuroscience 2006, 26:9022-9029.
18. Mines M.A., Yuskaitis C.J., King M.K., Beurel E., Jope R.S. GSK3 influences social preference and anxiety-related behaviors during social interaction in a mouse model of fragile X syndrome and autism. PLoS ONE 2010, 5:e9706.
19. Jedynak P., Jaholkowski P., Wozniak G., Sandi C., Kaczmarek L., Filipkowski R.K. Lack of cyclin D2 impairing adult brain neurogenesis alters hippocampal-dependent behavioral tasks without reducing learning ability. Behavioural Brain Research 2012, 227:159-166.
20. Spittaels K., Van den Haute C., Van Dorpe J., Geerts H., Mercken M., Bruynseels K., et al. Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice. Journal of Biological Chemistry 2000, 275:41340-41349.
21. Jaworski T., Dewachter I., Lechat B., Gees M., Kremer A., Demedts D., et al. GSK-3alpha/beta kinases and amyloid production in vivo. Nature 2011, 480:E4-E5. [discussion E6].
22. Gundersen H.J., Bagger P., Bendtsen T.F., Evans S.M., Korbo L., Marcussen N., et al. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. Apmis 1988, 96:857-881.
23. Deacon R.M., Rawlins J.N. Hippocampal lesions, species-typical behaviours and anxiety in mice. Behavioural Brain Research 2005, 156:241-249.
24. Deacon R.M. Digging and marble burying in mice: simple methods for in vivo identification of biological impacts. Nature Protocols 2006, 1:122-124.
25. Deacon R.M., Croucher A., Rawlins J.N. Hippocampal cytotoxic lesion effects on species-typical behaviours in mice. Behavioural Brain Research 2002, 132:203-213.
26. Kalueff A.V., Keisala T., Minasyan A., Kuuslahti M., Miettinen S., Tuohimaa P. Behavioural anomalies in mice evoked by "Tokyo" disruption of the Vitamin D receptor gene. Neuroscience Research 2006, 54:254-260.
27. Kempermann G., Gage F.H. Genetic influence on phenotypic differentiation in adult hippocampal neurogenesis. Brain Research. Developmental Brain Research 2002, 134:1-12.
28. Cryan J.F., Holmes A. The ascent of mouse: advances in modelling human depression and anxiety. Nature Reviews Drug Discovery 2005, 4:775-790.
29. 2 regulates stem cells through Wnt/beta-catenin signalling. Nature Cell Biology 2010, 12:1007-1013.
30. Mao Y., Ge X., Frank C.L., Madison J.M., Koehler A.N., Doud M.K., et al. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell 2009, 136:1017-1031.
31. Eom T.Y., Jope R.S. Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3alpha/beta impairs in vivo neural precursor cell proliferation. Biological Psychiatry 2009, 66:494-502.
32. Fuster-Matanzo A., Llorens-Martin M., Sirerol-Piquer M.S., Garcia-Verdugo J.M., Avila J., Hernandez F. Dual effects of increased glycogen synthase kinase-3beta activity on adult neurogenesis. Human Molecular Genetics 2013, 22:1300-1315.
33. Llorens-Martin M., Fuster-Matanzo A., Teixeira C.M., Jurado-Arjona J., Ulloa F., Defelipe J., et al. GSK-3beta overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo. Molecular Psychiatry 2013, 18:451-460.
34. Dagyte G., Crescente I., Postema F., Seguin L., Gabriel C., Mocaer E., et al. Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress. Behavioural Brain Research 2011, 218:121-128.
35. Bersudsky Y., Shaldubina A., Kozlovsky N., Woodgett J.R., Agam G., Belmaker R.H. Glycogen synthase kinase-3beta heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results. Behavioural Pharmacology 2008, 19:217-224.