Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6- carbonitrile derivatives acting as antimicrobial agents

European Journal of Medicinal Chemistry

Volumn 64, Issue , 2013, Pages 314-320

  Kanawade, Shrikant B ^a   Toche, Raghunath B ^a   Rajani, Dhanji P ^b  

^a K T H M COLLEGE   (India)

^b Microcare Laboratory   (India)

Author keywords

4 Chlorothieno 2,3 d pyrimidine; Conventional method; Ipso substitution; Non conventional green method; Thieno 2,3 d pyrimidine

Indexed keywords

4 ( 2 CHLOROPHENYLAMINO) 5 ( 4 CHLOROPHENYL)THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 4 ( 4 (BENZO[D]ISOTHIAZOL 3 YL)PIPERAZIN 1 YL) 5 ( 4 CHLOROPHENYL)THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 4 (BENZYLAMINO) 5 ( 4 CHLOROPHENYL)THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 4 CHLORO 5 ( 4 CHLOROPHENYL)THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 5 ( 4 CHLOROPHENYL) 3,4 DIHYDRO 4 OXOTHIENO[2,3 D]PYRIMIDINE 6 CARBOXAMIDE; 5 ( 4 CHLOROPHENYL) 4 ( 2,3 DIHYDROBENZO[B][1,4]DIOXIN 3 YL)(PIPERAZIN 1 YL)METHANONE THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 5 ( 4 CHLOROPHENYL) 4 ( 4 ( 2,3 DICHLOROPHENYL)PIPERAZIN 1 YL)THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 5 ( 4 CHLOROPHENYL) 4 (DIETHYLAMINO)THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 5 ( 4 CHLOROPHENYL) 4 (PIPERAZIN 1 YL)THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 5 ( 4 CHLOROPHENYL) 4 (PIPERIDIN 1 YL)THIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 5 ( 4 CHLOROPHENYL) 4 MORPHOLINOTHIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; 5 ( 5 CHLOROPHENYL) 3,4 DIHYDRO 4 OXOTHIENO[2,3 D]PYRIMIDINE 6 CARBONITRILE; AMINE; AMPICILLIN; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; CHLORAMPHENICOL; CIPROFLOXACIN; ETHYL 4 ( 5 ( 4 CHLOROPHENYL) 6 CYANOTHIENO[2,3 D]PYRIMIDIN 4 YL)PIPERAZINE 1 CARBOXYLIC ACID; GENTAMICIN; GRISEOFULVIN; NITRILE; NORFLOXACIN; NYSTATIN; OXOTHIENO[2,3 D]PYRIMIDINE 6 CARBOXAMIDE; PHOSPHORUS DERIVATIVE; PHOSPHORUS PENTACHLORIDE; PHOSPHORUSOXYCHLORIDE; THIENO[2,3 D]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS CLAVATUS; ASPERGILLUS NIGER; BACTERIAL STRAIN; BROTH DILUTION; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; FUNGAL STRAIN; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; REACTION ANALYSIS; STAPHYLOCOCCUS AUREUS; STEREOCHEMISTRY; STREPTOCOCCUS PYOGENES; THERMAL ANALYSIS;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; BENZOXAZINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FUNGI; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PIPERIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84877027504     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.03.039     Document Type: Article

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