Identification of 7-phenylaminothieno-[3,2-b]pyridine-6-carbonitriles as a new class of Src kinase inhibitors

Journal of Medicinal Chemistry

Volumn 47, Issue 27, 2004, Pages 6666-6668

  Boschelli, Diane H ^a   Wu, Biqi ^a   Sosa, Ana Carolina Barrios ^a   Durutlic, Haris ^a   Ye, Fei ^a   Raifeld, Yuri ^a   Golas, Jennifer M ^a   Boschelli, Frank ^a  

^a WYETH RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 QUINOLINECARBONITRILE; 7 PHENYLAMINOTHIENO[3,2 B]PYRIDINE 6 CARBONITRILE DERIVATIVE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; QUINOLINE DERIVATIVE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

ENZYME INHIBITORS; PYRIDINES; SRC-FAMILY KINASES; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 11144244600     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049237m     Document Type: Article

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22. Compounds were tested at least twice with the standard deviation reported within the brackets.