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Volumn 15, Issue 2, 2013, Pages 511-522

Effect of device design on the aerosolization of a carrier-based dry powder inhaler - A case study on aerolizer® foradile®

Author keywords

aerosolization; computational fluid dynamics; device design; discrete element method; dry powder inhalers

Indexed keywords

DRUG CARRIER; FORMOTEROL FUMARATE;

EID: 84877024842     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-013-9458-6     Document Type: Article
Times cited : (62)

References (22)
  • 1
    • 33645467770 scopus 로고    scopus 로고
    • Dry powder aerosol delivery systems: Current and future research directions
    • 10.1089/jam.2006.19.21 1:CAS:528:DC%2BD28Xis1Gksb4%3D
    • Chan HK. Dry powder aerosol delivery systems: Current and future research directions. J Aerosol Med Depos Clearance Eff Lung. 2006;19(1):21-7.
    • (2006) J Aerosol Med Depos Clearance Eff Lung , vol.19 , Issue.1 , pp. 21-27
    • Chan, H.K.1
  • 2
    • 84858618162 scopus 로고    scopus 로고
    • Drug-lactose binding aspects in adhesive mixtures: Controlling performance in dry powder inhaler formulations by altering lactose carrier surfaces
    • 21782866 10.1016/j.addr.2011.07.002 1:CAS:528:DC%2BC38Xkt1Cquro%3D
    • Zhou Q, Morton DAV. Drug-lactose binding aspects in adhesive mixtures: Controlling performance in dry powder inhaler formulations by altering lactose carrier surfaces. Adv Drug Deliv Rev. 2012;64(3):275-84.
    • (2012) Adv Drug Deliv Rev , vol.64 , Issue.3 , pp. 275-284
    • Zhou, Q.1    Morton, D.A.V.2
  • 3
    • 84858620546 scopus 로고    scopus 로고
    • A critical view on lactose-based drug formulation and device studies for dry powder inhalation: Which are relevant and what interactions to expect?
    • 21565232 10.1016/j.addr.2011.04.004
    • De Boer AH, Chan HK, Price R. A critical view on lactose-based drug formulation and device studies for dry powder inhalation: Which are relevant and what interactions to expect? Adv Drug Deliv Rev. 2012;64(3):257-74.
    • (2012) Adv Drug Deliv Rev , vol.64 , Issue.3 , pp. 257-274
    • De Boer, A.H.1    Chan, H.K.2    Price, R.3
  • 4
    • 0037032434 scopus 로고    scopus 로고
    • Deagglomeration of dry powder pharmaceutical aerosols
    • 12429458 10.1016/S0378-5173(02)00319-8 1:CAS:528:DC%2BD38XosFags7g%3D
    • Voss A, Finlay WH. Deagglomeration of dry powder pharmaceutical aerosols. Int J Pharm. 2002;248(1-2):39-50.
    • (2002) Int J Pharm , vol.248 , Issue.1-2 , pp. 39-50
    • Voss, A.1    Finlay, W.H.2
  • 5
    • 8644282632 scopus 로고    scopus 로고
    • Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 1: Grid structure and mouthpiece length
    • 15389665 10.1002/jps.20201 1:CAS:528:DC%2BD2cXpvV2itrs%3D
    • Coates MS, Fletcher DF, Chan HK, Raper JA. Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 1: grid structure and mouthpiece length. J Pharm Sci. 2004;93(11):2863-76.
    • (2004) J Pharm Sci , vol.93 , Issue.11 , pp. 2863-2876
    • Coates, M.S.1    Fletcher, D.F.2    Chan, H.K.3    Raper, J.A.4
  • 6
    • 33745056503 scopus 로고    scopus 로고
    • Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 2: Air inlet size
    • 16625656 10.1002/jps.20603 1:CAS:528:DC%2BD28XlsFWlsbk%3D
    • Coates MS, Chan HK, Fletcher DF, Raper JA. Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 2: Air inlet size. J Pharm Sci. 2006;95(6):1382-92.
    • (2006) J Pharm Sci , vol.95 , Issue.6 , pp. 1382-1392
    • Coates, M.S.1    Chan, H.K.2    Fletcher, D.F.3    Raper, J.A.4
  • 7
    • 34250840026 scopus 로고    scopus 로고
    • Influence of mouthpiece geometry on the aerosol delivery performance of a dry powder inhaler
    • 17404813 10.1007/s11095-007-9262-z 1:CAS:528:DC%2BD2sXmvVyqt78%3D
    • Coates MS, Chan HK, Fletcher DF, Chiou H. Influence of mouthpiece geometry on the aerosol delivery performance of a dry powder inhaler. Pharm Res. 2007;24(8):1450-6.
    • (2007) Pharm Res , vol.24 , Issue.8 , pp. 1450-1456
    • Coates, M.S.1    Chan, H.K.2    Fletcher, D.F.3    Chiou, H.4
  • 8
    • 84855892066 scopus 로고    scopus 로고
    • Dry powder inhaler device influence on carrier particle performance
    • 22095397 10.1002/jps.22824 1:CAS:528:DC%2BC3MXhsVOkt7fM
    • Donovan MJ, Kim SH, Raman V, Smyth HD. Dry powder inhaler device influence on carrier particle performance. J Pharm Sci. 2012;101(3):1097-107.
    • (2012) J Pharm Sci , vol.101 , Issue.3 , pp. 1097-1107
    • Donovan, M.J.1    Kim, S.H.2    Raman, V.3    Smyth, H.D.4
  • 9
    • 84869139244 scopus 로고    scopus 로고
    • Effect of device design on the in vitro performance and comparability for capsule-based dry powder inhalers
    • Shur J, Lee S, Adams W, Lionberger R, Tibbatts J, Price R. Effect of device design on the in vitro performance and comparability for capsule-based dry powder inhalers. AAPS J. 2012;14(4):667-676.
    • (2012) AAPS J. , vol.14 , Issue.4 , pp. 667-676
    • Shur, J.1    Lee, S.2    Adams, W.3    Lionberger, R.4    Tibbatts, J.5    Price, R.6
  • 10
    • 84892545348 scopus 로고    scopus 로고
    • CFD-DEM investigation of the dispersion mechanisms in commercial dry powder inhalers
    • doi: 10.1016/j.powtec.2012.07.012 2012
    • Tong ZB, Zheng B, Yang RY, Yu AB, Chan HK (2012). CFD-DEM investigation of the dispersion mechanisms in commercial dry powder inhalers. Powder Technol. 2012. doi: 10.1016/j.powtec.2012.07.012.
    • (2012) Powder Technol
    • Tong, Z.B.1    Zheng, B.2    Yang, R.Y.3    Yu, A.B.4    Chan, H.K.5
  • 11
    • 37849013359 scopus 로고    scopus 로고
    • Composite carriers improve the aerosolisation efficiency of drugs for respiratory delivery
    • 10.1016/j.jaerosci.2007.10.003 1:CAS:528:DC%2BD1cXlvVGqsg%3D%3D
    • Young PM, Roberts D, Chiou H, Rae W, Chan HK, Traini D. Composite carriers improve the aerosolisation efficiency of drugs for respiratory delivery. J Aerosol Sci. 2008;39(1):82-93.
    • (2008) J Aerosol Sci , vol.39 , Issue.1 , pp. 82-93
    • Young, P.M.1    Roberts, D.2    Chiou, H.3    Rae, W.4    Chan, H.K.5    Traini, D.6
  • 12
    • 0030975115 scopus 로고    scopus 로고
    • Calibration at different flow rates of a multistage liquid impinger
    • 10.1080/02786829708965456 1:CAS:528:DyaK2sXktVOhs7k%3D
    • Asking L, Olsson B. Calibration at different flow rates of a multistage liquid impinger. Aerosol Sci Technol. 1997;27(1):39-49.
    • (1997) Aerosol Sci Technol , vol.27 , Issue.1 , pp. 39-49
    • Asking, L.1    Olsson, B.2
  • 13
    • 0035656483 scopus 로고    scopus 로고
    • In vitro aerosol performance and dose uniformity between the Foradile (R) Aerolizer (R) and the Oxis (R) Turbuhaler (R)
    • 10.1089/08942680152744703 1:STN:280:DC%2BD38%2Fms1Wjsg%3D%3D
    • Chew NYK, Chan HK. In vitro aerosol performance and dose uniformity between the Foradile (R) Aerolizer (R) and the Oxis (R) Turbuhaler (R). J Aerosol Med Depos Clearance Eff Lung. 2001;14(4):495-501.
    • (2001) J Aerosol Med Depos Clearance Eff Lung , vol.14 , Issue.4 , pp. 495-501
    • Chew, N.Y.K.1    Chan, H.K.2
  • 14
    • 77951207948 scopus 로고    scopus 로고
    • Can low-dose combination products for inhalation be formulated in single crystalline particles?
    • 20172026 10.1016/j.ejps.2010.02.004 1:CAS:528:DC%2BC3cXks1Ghsbw%3D
    • Kumon M, Kwok PCL, Adi H, Heng D, Chan HK. Can low-dose combination products for inhalation be formulated in single crystalline particles? Eur J Pharm Sci. 2010;40(1):16-24.
    • (2010) Eur J Pharm Sci , vol.40 , Issue.1 , pp. 16-24
    • Kumon, M.1    Kwok, P.C.L.2    Adi, H.3    Heng, D.4    Chan, H.K.5
  • 15
    • 34249730944 scopus 로고    scopus 로고
    • Discrete particle simulation of particulate systems: Theoretical developments
    • 10.1016/j.ces.2006.12.089 1:CAS:528:DC%2BD2sXmtVaqtr8%3D
    • Zhu HP, Zhou ZY, Yang RY, Yu AB. Discrete particle simulation of particulate systems: Theoretical developments. Chem Eng Sci. 2007;62(13):3378-96.
    • (2007) Chem Eng Sci , vol.62 , Issue.13 , pp. 3378-3396
    • Zhu, H.P.1    Zhou, Z.Y.2    Yang, R.Y.3    Yu, A.B.4
  • 16
    • 33746363502 scopus 로고    scopus 로고
    • Numerical study of gas-solid flow in a cyclone separator
    • 10.1016/j.apm.2006.03.011
    • Wang B, Xu DL, Chu KW, Yu AB. Numerical study of gas-solid flow in a cyclone separator. Appl Math Model. 2006;30(11):1326-42.
    • (2006) Appl Math Model , vol.30 , Issue.11 , pp. 1326-1342
    • Wang, B.1    Xu, D.L.2    Chu, K.W.3    Yu, A.B.4
  • 17
    • 0016497477 scopus 로고
    • Progress in development of a Reynolds-stress turbulence closure
    • 10.1017/S0022112075001814
    • Launder BE, Reece GJ, Rodi W. Progress in development of a Reynolds-stress turbulence closure. J Fluid Mech. 1975;68:537-66.
    • (1975) J Fluid Mech , vol.68 , pp. 537-566
    • Launder, B.E.1    Reece, G.J.2    Rodi, W.3
  • 18
    • 67349109778 scopus 로고    scopus 로고
    • CFD-DEM modelling of multiphase flow in dense medium cyclones
    • 10.1016/j.powtec.2009.03.015 1:CAS:528:DC%2BD1MXmtVWksLg%3D
    • Chu KW, Wang B, Yu AB, Vince A. CFD-DEM modelling of multiphase flow in dense medium cyclones. Powder Technol. 2009;193(3):235-47.
    • (2009) Powder Technol , vol.193 , Issue.3 , pp. 235-247
    • Chu, K.W.1    Wang, B.2    Yu, A.B.3    Vince, A.4
  • 19
    • 24044542653 scopus 로고    scopus 로고
    • Influence of air flow on the performance of a dry powder inhaler using computational and experimental analyses
    • 16132356 10.1007/s11095-005-6155-x 1:CAS:528:DC%2BD2MXptVWlurg%3D
    • Coates MS, Chan HK, Fletcher DF, Raper JA. Influence of air flow on the performance of a dry powder inhaler using computational and experimental analyses. Pharm Res. 2005;22(9):1445-53.
    • (2005) Pharm Res , vol.22 , Issue.9 , pp. 1445-1453
    • Coates, M.S.1    Chan, H.K.2    Fletcher, D.F.3    Raper, J.A.4
  • 20
    • 0027228520 scopus 로고
    • The relationship between powder inhaler resistance and peak inspiratory conditions in healthy volunteers - Implications for in vitro testing
    • 10.1089/jam.1993.6.99 1:STN:280:DyaK2cbgsFGhsQ%3D%3D
    • Clark AR, Hollingworth AM. The relationship between powder inhaler resistance and peak inspiratory conditions in healthy volunteers - implications for In vitro testing. J Aerosol Med Depos Clearance Eff Lung. 1993;6(2):99-110.
    • (1993) J Aerosol Med Depos Clearance Eff Lung , vol.6 , Issue.2 , pp. 99-110
    • Clark, A.R.1    Hollingworth, A.M.2
  • 21
    • 0032416309 scopus 로고    scopus 로고
    • Dry powder inhalers: The influence of device resistance and powder formulation on drug and lactose deposition in vitro
    • 9845780 10.1016/S0928-0987(98)00008-6 1:CAS:528:DyaK1cXnvVSrsb8%3D
    • Srichana T, Martin GP, Marriott C. Dry powder inhalers: The influence of device resistance and powder formulation on drug and lactose deposition in vitro. Eur J Pharm Sci. 1998;7(1):73-80.
    • (1998) Eur J Pharm Sci , vol.7 , Issue.1 , pp. 73-80
    • Srichana, T.1    Martin, G.P.2    Marriott, C.3
  • 22
    • 77953957709 scopus 로고    scopus 로고
    • Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders
    • 20433919 10.1016/j.ejps.2010.04.012 1:CAS:528:DC%2BC3cXnvVOrsbY%3D
    • Zhou QT, Armstrong B, Larson I, Stewart PJ, Morton DAV. Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders. Eur J Pharm Sci. 2010;40(5):412-21.
    • (2010) Eur J Pharm Sci , vol.40 , Issue.5 , pp. 412-421
    • Zhou, Q.T.1    Armstrong, B.2    Larson, I.3    Stewart, P.J.4    Morton, D.A.V.5


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