Modifying the role of serotonergic 5-HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: A preliminary study

Genes, Brain and Behavior

Volumn 11, Issue 8, 2012, Pages 1001-1008

  Nielsen, D A ^a,b   Harding, M J ^a,b   Hamon, S C ^c   Huang, W ^a,b   Kosten, T R ^a,b  

^a Menninger Department of Psychiatry and Behavioral Sciences   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Cocaine; Disulfiram; Gene; Polymorphism; Serotonin; Treatment

Indexed keywords

COCAINE; DISULFIRAM; METHADONE; OPIATE; PLACEBO; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE 2; SEROTONIN; SLC6A4 PROTEIN, HUMAN; TPH2 PROTEIN, HUMAN; TRYPTOPHAN HYDROXYLASE;

ADULT; ALCOHOL ABUSE; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DNA POLYMORPHISM; DRUG EFFICACY; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC VARIABILITY; GENETICS; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OPIATE ADDICTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; URINALYSIS; ALLELE; BLOOD; CLINICAL TRIAL; COCAINE-RELATED DISORDERS; COMORBIDITY; DRUG EFFECTS; HEROIN DEPENDENCE; HETEROZYGOTE DETECTION; MIDDLE AGED; MULTICENTER STUDY; URINE;

ADULT; ALLELES; COCAINE; COCAINE-RELATED DISORDERS; COMORBIDITY; DISULFIRAM; FEMALE; GENETIC VARIATION; GENOTYPE; HEROIN DEPENDENCE; HETEROZYGOTE DETECTION; HUMANS; MALE; METHADONE; MIDDLE AGED; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TRYPTOPHAN HYDROXYLASE;

EID: 84876973165     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2012.00839.x     Document Type: Article

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