Dual functions for cytosolic α-mannosidase (Man2C1) its down-regulation causes mitochondria-dependent apoptosis independently of its α-mannosidase activity

Journal of Biological Chemistry

Volumn 288, Issue 17, 2013, Pages 11887-11896

  Wang, Li ^a   Suzuki, Tadashi ^a  

^a RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC SIGNALING; DOWN-REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HOMOLOGOUS PROTEINS; MAMMALIAN CELLS; MITOTIC ARREST; STRESS-INDUCED;

CELL MEMBRANES; TRANSCRIPTION FACTORS;

CELL DEATH;

ALPHA MANNOSIDASE; CASPASE 3; CASPASE 8; GLYCAN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SHORT HAIRPIN RNA;

APOPTOSIS; ARTICLE; CARBOHYDRATE METABOLISM; CATABOLISM; CONTROLLED STUDY; CYSTOLIC ALPHA MANNOSIDASE GENE; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SILENCING; HELA CELL; MITOCHONDRION; MUTANT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; CARBOHYDRATE METABOLISM; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HEP G2 CELLS; HUMANS; MANNOSIDASES; MITOCHONDRIA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP;

MAMMALIA;

EID: 84876942141     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.425702     Document Type: Article

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