Modeling and monitoring of polymorphic transformations during the drying phase of wet granulation

Pharmaceutical Research

Volumn 21, Issue 5, 2004, Pages 860-866

  Davis, Tiffani D ^a,b   Peck, Garnet E ^a   Stowell, Joseph G ^a   Morris, Kenneth R ^a   Byrn, Stephen R ^a  

^a PURDUE UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Fluid bed drying; Glycine; Near infrared spectroscopy; Polymorphism; Tray drying

Indexed keywords

GLYCINE;

ARTICLE; DATA ANALYSIS; DRUG GRANULATION; DRUG SOLUBILITY; DRY POWDER; EXPERIMENTAL MODEL; NEAR INFRARED SPECTROSCOPY; PREDICTION; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RATING SCALE; WETTABILITY; X RAY POWDER DIFFRACTION;

CALIBRATION; CELLULOSE; DESICCATION; DRUG COMPOUNDING; EXCIPIENTS; GLYCINE; MODELS, MOLECULAR; MODELS, STATISTICAL; MOLECULAR CONFORMATION; PHARMACEUTICAL SOLUTIONS; POLYMERS; POWDERS; SOLUBILITY;

EID: 3543045038     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000026440.00508.cf     Document Type: Article

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