-
1
-
-
36849148382
-
The RNA world
-
Gilbert, W. The RNA world. Nature 319, 618 (1986
-
(1986)
Nature
, vol.319
, pp. 618
-
-
Gilbert, W.1
-
2
-
-
0024476917
-
RNA evolution and the origins of life
-
Joyce, G. F. RNA evolution and the origins of life. Nature 338, 217-224 (1989
-
(1989)
Nature
, vol.338
, pp. 217-224
-
-
Joyce, G.F.1
-
3
-
-
0003604405
-
-
2nd edn (eds R. F. Gesteland & J. F. Atkins) Cold Spring Harbor Laboratory Press
-
Joyce, G. F. & Orgel, L. E. in The RNAWorld 2nd edn (eds R. F. Gesteland & J. F. Atkins) 49-77 (Cold Spring Harbor Laboratory Press, 1999
-
(1999)
RNA World
, pp. 49-77
-
-
Joyce, G.F.1
Orgel, L.E.2
-
4
-
-
0034637111
-
The complete atomic structure of the large ribosomal subunit at 2.4 Ångstrom resolution
-
Ban, N., Nissen, P., Hansen, J., Moore, P. B. & Steitz, T. A. The complete atomic structure of the large ribosomal subunit at 2.4 Ångstrom resolution. Science 289, 905-920 (2000
-
(2000)
Science
, vol.289
, pp. 905-920
-
-
Ban, N.1
Nissen, P.2
Hansen, J.3
Moore, P.B.4
Steitz, T.A.5
-
5
-
-
0034637161
-
The structural basis of ribosome activity in peptide bond synthesis
-
Nissen, P., Hansen, J., Ban, N., Moore, P. B. & Steitz, T. A. The structural basis of ribosome activity in peptide bond synthesis. Science 289, 920-930 (2000
-
(2000)
Science
, vol.289
, pp. 920-930
-
-
Nissen, P.1
Hansen, J.2
Ban, N.3
Moore, P.B.4
Steitz, T.A.5
-
6
-
-
66149108671
-
Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions
-
Powner, M.W., Gerland, B. & Sutherland, J. D. Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions. Nature 459, 239-242 (2009
-
(2009)
Nature
, vol.459
, pp. 239-242
-
-
Powner, M.W.1
Gerland, B.2
Sutherland, J.D.3
-
7
-
-
78649927354
-
Chemoselective multicomponent one-pot assembly of purine precursors in water
-
Powner, M. W., Sutherland, J. D. & Szostak, J. W. Chemoselective multicomponent one-pot assembly of purine precursors in water. J. Am. Chem. Soc. 132, 16677-16688 (2010
-
(2010)
J. Am. Chem. Soc
, vol.132
, pp. 16677-16688
-
-
Powner, M.W.1
Sutherland, J.D.2
Szostak, J.W.3
-
8
-
-
77953942525
-
Phosphate-mediated interconversion of riboand arabino-configured prebiotic nucleotide intermediates
-
Powner, M.W. & Sutherland, J. D. Phosphate-mediated interconversion of riboand arabino-configured prebiotic nucleotide intermediates. Angew. Chem. Int. Ed. 49, 4641-4643 (2010
-
(2010)
Angew. Chem. Int. Ed.
, vol.49
, pp. 4641-4643
-
-
Powner, M.W.1
Sutherland, J.D.2
-
9
-
-
0029876064
-
Synthesis of long prebiotic oligomers on mineral surfaces
-
Ferris, J. P. Jr, Hill, A. R., Liu, R. & Orgel, L. E. Synthesis of long prebiotic oligomers on mineral surfaces. Nature 381, 59-61 (1996
-
(1996)
Nature
, vol.381
, pp. 59-61
-
-
Ferris Jr., J.P.1
Hill, A.R.2
Liu, R.3
Orgel, L.E.4
-
10
-
-
0035453348
-
Eutectic phases in ice facilitate nonenzymatic nucleic acid synthesis
-
Kanavarioti, A., Monnard, P-A. & Deamer, D.W. Eutectic phases in ice facilitate nonenzymatic nucleic acid synthesis. Astrobiology 1, 271-281 (2001
-
(2001)
Astrobiology
, vol.1
, pp. 271-281
-
-
Kanavarioti, A.1
Monnard, P.-A.2
Deamer, D.W.3
-
11
-
-
0027746565
-
The limits of template-directed synthesis with nucleoside-5'-phosphoro(2- methyl)imidazolides
-
Hill, A. J., Orgel, L. & Wu, T. The limits of template-directed synthesis with nucleoside-5'-phosphoro(2-methyl)imidazolides. Origins Life Evol. Biospheres 23, 285-290 (1993
-
(1993)
Origins Life Evol. Biospheres
, vol.23
, pp. 285-290
-
-
Hill, A.J.1
Orgel, L.2
Wu, T.3
-
12
-
-
3042709433
-
Prebiotic chemistry and the origin of the RNA world
-
Orgel, L. E. Prebiotic chemistry and the origin of the RNA world. Crit. Rev. Biochem. Mol. Biol. 39, 99-123 (2004
-
(2004)
Crit. Rev. Biochem. Mol. Biol
, vol.39
, pp. 99-123
-
-
Orgel, L.E.1
-
13
-
-
79960684944
-
Efficient enzyme-free copying of all four nucleobases templated by immobilized RNA
-
Deck, C., Jauker, M. & Richert, C. Efficient enzyme-free copying of all four nucleobases templated by immobilized RNA. Nature Chem. 3, 603-608 (2011
-
(2011)
Nature Chem
, vol.3
, pp. 603-608
-
-
Deck, C.1
Jauker, M.2
Richert, C.3
-
14
-
-
84864875884
-
The eightfold path to non-enzymatic RNA replication
-
10.1186/1759-2208-3-2
-
Szostak, J. W. The eightfold path to non-enzymatic RNA replication. J. Syst. Chem. 3, 2 doi: 10.1186/1759-2208-3-2 (2012
-
(2012)
J. Syst. Chem
, vol.3
, Issue.2
-
-
Szostak, J.W.1
-
15
-
-
0023372377
-
The case for an ancestral genetic system involving simple analogues of the nucleotides
-
Joyce, G. F., Schwartz, A.W., Miller, S. L. & Orgel, L. E. The case for an ancestral genetic system involving simple analogues of the nucleotides. Proc. Natl Acad. Sci. USA 84, 4398-4402 (1987
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 4398-4402
-
-
Joyce, G.F.1
Schwartz, A.W.2
Miller, S.L.3
Orgel, L.E.4
-
16
-
-
0027364174
-
PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules
-
Egholm, M. et al. PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature 365, 566-568 (1993
-
(1993)
Nature
, vol.365
, pp. 566-568
-
-
Egholm, M.1
-
17
-
-
0029896648
-
Nonionic analogs of RNA with dimethylene sulfone bridges
-
Richert, C., Roughton, A. L. & Benner, S. A. Nonionic analogs of RNA with dimethylene sulfone bridges. J. Am. Chem. Soc. 118, 4518-4531 (1996
-
(1996)
J. Am. Chem. Soc
, vol.118
, pp. 4518-4531
-
-
Richert, C.1
Roughton, A.L.2
Benner, S.A.3
-
18
-
-
0344326234
-
Chemical etiology of nucleic acid structure
-
Eschenmoser, A. Chemical etiology of nucleic acid structure. Science 284, 2118-2124 (1999
-
(1999)
Science
, vol.284
, pp. 2118-2124
-
-
Eschenmoser, A.1
-
19
-
-
0033709099
-
Nonenzymatic oligomerization on templates containing phosphodiester- linked acyclic glycerol nucleic acid analogues
-
Chaput, J. C. & Switzer, C. Nonenzymatic oligomerization on templates containing phosphodiester-linked acyclic glycerol nucleic acid analogues. J. Mol. Evol. 51, 464-470 (2000
-
(2000)
J. Mol. Evol
, vol.51
, pp. 464-470
-
-
Chaput, J.C.1
Switzer, C.2
-
20
-
-
29244437563
-
Glyoxylate as a backbone linkage for a prebiotic ancestor of RNA
-
Bean, H. D., Anet, F. A. L., Gould, I. R. & Hud, N. V. Glyoxylate as a backbone linkage for a prebiotic ancestor of RNA. Origins Life Evol. Biospheres 36, 39-63 (2006
-
(2006)
Origins Life Evol. Biospheres
, vol.36
, pp. 39-63
-
-
Bean, H.D.1
Anet, F.A.L.2
Gould, I.R.3
Hud, N.V.4
-
21
-
-
64549154434
-
N2'-P3' phosphoramidate glycerol nucleic acid as a potential alternative genetic system
-
Chen, J. J., Cai, X. & Szostak, J. W. N2'-P3' phosphoramidate glycerol nucleic acid as a potential alternative genetic system. J. Am. Chem. Soc. 131, 2119-2121 (2009
-
(2009)
J. Am. Chem. Soc
, vol.131
, pp. 2119-2121
-
-
Chen, J.J.1
Cai, X.2
Szostak, J.W.3
-
23
-
-
0000806492
-
Hydrolytic stability of helical RNA - selective advantage for the natural 3',5'-bond
-
Usher, D. A. & McHale, A. H. Hydrolytic stability of helical RNA - selective advantage for the natural 3',5'-bond. Proc. Natl Acad. Sci. USA 73, 1149-1153 (1976
-
(1976)
Proc. Natl Acad. Sci. USA
, vol.73
, pp. 1149-1153
-
-
Usher, D.A.1
McHale, A.H.2
-
24
-
-
0019333283
-
Catalysis of accurate poly (C)-directed synthesis of 3'-5'-linked oligoguanylates by Zn2+
-
Bridson, P. K. & Orgel, L. E. Catalysis of accurate poly(C)-directed synthesis of 3'-5'-linked oligoguanylates by Zn2+. J. Mol. Biol. 144, 567-577 (1980
-
(1980)
J. Mol. Biol
, Issue.144
, pp. 567-577
-
-
Bridson, P.K.1
Orgel, L.E.2
-
25
-
-
0020370504
-
Oligomerization of (guanosine-5'-phosphor) 2- methylimidazole on poly(C) - an RNA-polymerase model
-
Inoue, T. & Orgel, L. E. Oligomerization of (guanosine-5'-phosphor)- 2- methylimidazole on poly(C) - an RNA-polymerase model. J. Mol. Biol. 162, 201-217 (1982
-
(1982)
J. Mol. Biol
, Issue.162
, pp. 201-217
-
-
Inoue, T.1
Orgel, L.E.2
-
26
-
-
0029915714
-
Nonenzymatic template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds
-
Rohatgi, R., Bartel, D. P. & Szostak, J. W. Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds. J. Am. Chem. Soc. 118, 3340-3344 (1996
-
(1996)
J. Am. Chem. Soc
, vol.118
, pp. 3340-3344
-
-
Rohatgi, R.1
Bartel, D.P.2
Szostak, J.W.3
-
27
-
-
0029832218
-
RNA-catalysed RNA polymerization using nucleoside triphosphates
-
Ekland, E. H. & Bartel, D. P. RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature 382, 373-376 (1996
-
(1996)
Nature
, vol.382
, pp. 373-376
-
-
Ekland, E.H.1
Bartel, D.P.2
-
28
-
-
0035906978
-
RNA-catalyzed RNA polymerization: Accurate and general RNA-templated primer extension
-
Johnston, W. K., Unrau, P. J., Lawrence, M. S., Glasner, M. E. & Bartel, D. P. RNA-catalyzed RNA polymerization: Accurate and general RNA-templated primer extension. Science 292, 1319-1325 (2001
-
(2001)
Science
, vol.292
, pp. 1319-1325
-
-
Johnston, W.K.1
Unrau, P.J.2
Lawrence, M.S.3
Glasner, M.E.4
Bartel, D.P.5
-
29
-
-
0030799343
-
Activity of 2',5'-linked RNA in the template-directed oligomerization of mononucleotides
-
Prakash, T. P., Roberts, C. & Switzer, C. Activity of 2',5'-linked RNA in the template-directed oligomerization of mononucleotides. Angew. Chem. Int. Ed. Engl. 36, 1522-1523 (1997
-
(1997)
Angew. Chem. Int. Ed. Engl
, vol.36
, pp. 1522-1523
-
-
Prakash, T.P.1
Roberts, C.2
Switzer, C.3
-
30
-
-
80051958795
-
Evolution of functional nucleic acids in the presence of nonheritable backbone heterogeneity
-
Trevino, S. G., Zhang, N., Elenko, M. P., Luptak, A. & Szostak, J.W. Evolution of functional nucleic acids in the presence of nonheritable backbone heterogeneity. Proc. Natl Acad. Sci. USA 108, 13492-13497 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 13492-13497
-
-
Trevino, S.G.1
Zhang, N.2
Elenko, M.P.3
Luptak, A.4
Szostak, J.W.5
-
31
-
-
0027445885
-
Oligoribonucleotides containing 2',5'- phosphodiester linkages exhibit binding selectivity for 3',5'-RNA over 3',5'-ssDNA
-
Giannaris, P. A. & Damha, M. J. Oligoribonucleotides containing 2',5'- phosphodiester linkages exhibit binding selectivity for 3',5'-RNA over 3',5'-ssDNA. Nucleic Acids Res. 21, 4742-4749 (1993
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 4742-4749
-
-
Giannaris, P.A.1
Damha, M.J.2
-
32
-
-
0032546612
-
Physicochemical And Biochemical Properties Of 2'5'-linked RNA And 2'5'-RNA: 3'5'-RNA 'hybrid' duplexes
-
Wasner, M. et al. Physicochemical and biochemical properties of 2',5'-linked RNA and 2',5'-RNA: 3',5'-RNA 'hybrid' duplexes. Biochemistry 37, 7478-7486 (1998
-
(1998)
Biochemistry
, vol.37
, pp. 7478-7486
-
-
Wasner, M.1
-
33
-
-
0027995790
-
Isolation of RNA aptamers for biological cofactors by in-vitro selection
-
Burgstaller, P. & Famulok, M. Isolation of RNA aptamers for biological cofactors by in-vitro selection. Angew. Chem. Int. Ed. Engl. 33, 1084-1087 (1994
-
(1994)
Angew. Chem. Int. Ed. Engl
, vol.33
, pp. 1084-1087
-
-
Burgstaller, P.1
Famulok, M.2
-
34
-
-
0029864853
-
Molecular recognition in the FMN-RNA aptamer complex
-
Fan, P., Suri, A. K., Fiala, R., Live, D. & Patel, D. J. Molecular recognition in the FMN-RNA aptamer complex. J. Mol. Biol. 258, 480-500 (1996
-
(1996)
J. Mol. Biol
, vol.258
, pp. 480-500
-
-
Fan, P.1
Suri, A.K.2
Fiala, R.3
Live, D.4
Patel, D.J.5
-
35
-
-
0030939002
-
The structure, function and application of the hammerhead ribozyme
-
Birikh, K. R., Heaton, P. A. & Eckstein, F. The structure, function and application of the hammerhead ribozyme. Eur. J. Biochem. 245, 1-16 (1997
-
(1997)
Eur. J. Biochem
, vol.245
, pp. 1-16
-
-
Birikh, K.R.1
Heaton, P.A.2
Eckstein, F.3
-
36
-
-
0016849198
-
Oligonucleotide synthesis catalyzed by the Zn2+ ion
-
Hiraki, S. & Orgel, L. E. Oligonucleotide synthesis catalyzed by the Zn2+ ion. J. Am. Chem. Soc. 97, 3532-3533 (1975
-
(1975)
J. Am. Chem. Soc
, vol.97
, pp. 3532-3533
-
-
Hiraki, S.1
Orgel, L.E.2
-
37
-
-
0033546087
-
Cleavage activity of a hammerhead ribozyme domain containing 2',5'-phosphodiester linkages
-
Burlina, F., Fourrey, J., Lefort, V. & Favre, A. Cleavage activity of a hammerhead ribozyme domain containing 2',5'-phosphodiester linkages. Tetrahedron Lett. 40, 4559-4562 (1999
-
(1999)
Tetrahedron Lett
, vol.40
, pp. 4559-4562
-
-
Burlina, F.1
Fourrey, J.2
Lefort, V.3
Favre, A.4
-
38
-
-
0032832044
-
Ribozyme cleavage of a 2',5'-phosphodiester linkage: Mechanism and a restricted divalent metal-ion requirement
-
Shih, I. & Been, M. D. Ribozyme cleavage of a 2',5'-phosphodiester linkage: Mechanism and a restricted divalent metal-ion requirement. RNA 5, 1140-1148 (1999
-
(1999)
RNA
, vol.5
, pp. 1140-1148
-
-
Shih, I.1
Been, M.D.2
-
39
-
-
0029165074
-
Reverse transcriptase reads through a 2'-5' linkage and a 2'-thiophosphate in a template
-
Lorsch, J. R., Bartel, D. P. & Szostak, J. W. Reverse transcriptase reads through a 2'-5' linkage and a 2'-thiophosphate in a template. Nucleic Acids Res. 23, 2811-2814 (1995
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 2811-2814
-
-
Lorsch, J.R.1
Bartel, D.P.2
Szostak, J.W.3
-
40
-
-
84860013215
-
Synthetic genetic polymers capable of heredity and evolution
-
Pinheiro, V. B. et al. Synthetic genetic polymers capable of heredity and evolution. Science 336, 341-344 (2012
-
(2012)
Science
, vol.336
, pp. 341-344
-
-
Pinheiro, V.B.1
-
42
-
-
77952906690
-
Expanding roles for diverse physical phenomena during the origin of life
-
Budin, I. & Szostak, J. W. Expanding roles for diverse physical phenomena during the origin of life. Annu. Rev. Biophys. 39, 245-263 (2010
-
(2010)
Annu. Rev. Biophys
, vol.39
, pp. 245-263
-
-
Budin, I.1
Szostak, J.W.2
-
43
-
-
79955109405
-
Physical effects underlying the transition from primitive to modern cell membranes
-
Budin, I. & Szostak, J. W. Physical effects underlying the transition from primitive to modern cell membranes. Proc. Natl Acad. Sci. USA 108, 5249-5254 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 5249-5254
-
-
Budin, I.1
Szostak, J.W.2
-
44
-
-
0033922698
-
Analysis of drug-DNA binding data
-
Qu, X. G. & Chaires, J. B. Analysis of drug-DNA binding data. Method. Enzymol. 321, 353-369 (2000
-
(2000)
Method. Enzymol
, vol.321
, pp. 353-369
-
-
Qu, X.G.1
Chaires, J.B.2
|