Cleavage activity of a hammerhead ribozyme domain containing 2',5'- phosphodiester linkages

Tetrahedron Letters

Volumn 40, Issue 24, 1999, Pages 4559-4562

  Burlina, Fabienne ^a   Fourrey, Jean Louis ^b   Lefort, Valérie ^a   Favre, Alain ^a  

^a INSTITUT JACQUES MONOD   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHODIESTERASE; RIBOZYME;

ARTICLE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME DEGRADATION; ENZYME STABILITY; STRUCTURE ACTIVITY RELATION;

EID: 0033546087     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00809-6     Document Type: Article

References (20)

1. 1 Antisense Research and Application, Crooke, S. T., ed., Springer-Verlag, Berlin, 1998.
2. 2 Catalytic RNA, Eckstein, F. and Lilley, M. J., eds, Springer-Verlag, Berlin, 1996.
3. 3 (a) Burlina, F.; Favre, A.; Fourrey, J.-L. Bioorg. Med. Chem. 1997, 5, 1999-2010.
4. (b) Amarzguioui, M.. Prydz, H. Cell. Mol. Life Sci. 1998, 54, 1175-1202.
5. (c) Vaish, N. K.; Kore, A. R.; Eckstein, F. Nucleic Acids Res. 1998, 26, 5237-5242.
6. 4 (a) Yang, J.; Usman, N.; Chartrand, P.; Cedergren, R. Biochemistry 1992, 31, 5005-5009.
7. (b) Taylor, N.R.; Kaplan, B. E.; Swiderski, P.; Li, H.; Rossi, J. J. Nucleic Acids Res. 1992, 20, 4559-4565.
8. (c) Shimayama, T.; Nishikawa, T.; Nishikawa, S.; Taira, K. Nucleic Acids Res. 1993, 21, 2605-2611.
9. (d) Shimayama, T.; Nishikawa, T.; Taira, K. FEBS Lett. 1995, 368, 304-306.
10. (e) Hendry, P.; McCall, M. Nucleic Acids Res. 1995, 23, 3928-3936.
11. 5 Paolella, G.; Sproat, B. S.; Lamond, A. I. EMBO J. 1992, 11, 1913-1919.
12. 6 For hammerhead ribozyme numbering see: Hertel, K. J.; Pardi, A.; Uhlenbeck, O. C.; Koizumi, M.; Ohtsuka, E.; Uesugi, S.; Cedergren, R.; Eckstein, F.; Gerlach, W. L.; Hodgson, R.; Symons, R. H. Nucleic Acids Res. 1992, 20, 3252-3253.
13. 7 Giannaris, P. A.; Damha, M. J. Nucleic Acids Res. 1993, 21, 4742-4749.
14. 8 Woisard, A.; Fourrey, J.-L.; Favre, A. J. Mol. Biol. 1994, 239, 366-370.
15. 9 Burlina, F.; Favre, A.; Fourrey, J-L.; Thomas, M. J. Chem. Soc., Chem. Commun. 1996, 1623-1624.
16. 10 Premraj, B. J.; Yathindra, N. J. Biomol. Struct. Dynam. 1998, 16, 313-328.
17. 11 Eigen, M.; Hammes, G. G. Advan. Enzymol. 1963, 25, 1-38.
18. 12 Feldstein, P. A.; Buzayan, J. M.; van Tol, H.; de Bear, H.; Cough, G. R.; Gilham, P. T.; Bruening, G. Proc. Natl. Acad. ScI. USA 1990, 87, 2623-2627.
19. 13 Wedekind, J. E.; McKay, D. B. Annu. Rev. Biomol. Struct. 1998, 27, 475-502. and references cited.
20. 14 Murray, J. B.; Seyhan, A. A.; Walter, N. G.; Burke, J. M. Scott, W. G. Chem. Biol. 1998, 5, 587-595 and references cited.