N2′→ P3′ phosphoramidate glycerol nucleic acid as a potential alternative genetic system

Journal of the American Chemical Society

Volumn 131, Issue 6, 2009, Pages 2119-2121

  Chen, Jesse J ^a   Cai, Xin ^a   Szostak, Jack W ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASE-PAIRING; CARBON BACKBONE; CIRCULAR DICHROISM; DINUCLEOTIDES; GENETIC SYSTEMS; PHOSPHORAMIDATE; SELF-REPLICATING SYSTEM; THERMAL DENATURATIONS;

AMINES; CHAINS; DICHROISM; NUCLEIC ACIDS; PYROLYSIS;

GLYCEROL;

GLYCEROL NUCLEIC ACID; HETERODUPLEX; MONOMER; N2'-P3' PHOSPHORAMIDATE GLYCEROL NUCLEIC ACID; NUCLEIC ACID; NUCLEOSIDE; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG; AMIDE; BIOMIMETIC MATERIAL; DNA; DRUG DERIVATIVE; GLYCEROL; IMIDAZOLE DERIVATIVE; NUCLEOTIDE; PHOSPHORAMIDIC ACID; PHOSPHORIC ACID;

AMINATION; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYCLIZATION; DENATURATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR INTERACTION; NUCLEIC ACID STRUCTURE; PHOTOLYSIS; POLYMERIZATION; SOLID PHASE SYNTHESIS; STOICHIOMETRY; CHEMISTRY; GENETIC VARIABILITY; GENETICS; MASS SPECTROMETRY;

AMIDES; BIOMIMETIC MATERIALS; CIRCULAR DICHROISM; DNA; GENETIC STRUCTURES; GLYCEROL; IMIDAZOLES; NUCLEIC ACIDS; NUCLEOTIDES; PHOSPHORIC ACIDS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 64549154434     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja809069b     Document Type: Article

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