Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice

Journal of Nutritional Biochemistry

Volumn 24, Issue 5, 2013, Pages 788-795

  Morine, Melissa J ^a   Toomey, Sinead ^a   McGillicuddy, Fiona C ^a   Reynolds, Clare M ^a   Power, Karen A ^a   Browne, John A ^a   Loscher, Christine ^b   Mills, Kingston H G ^c   Roche, Helen M ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b DUBLIN CITY UNIVERSITY   (Ireland)

^c TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Adipose tissue; IL 1 receptor type I; Inflammation; Insulin resistance; Network analysis; Transcriptomic profiling

Indexed keywords

INTERLEUKIN 1 RECEPTOR; STAT3 PROTEIN; TRANSCRIPTOME;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; GENE EXPRESSION; INSULIN RESISTANCE; KNOCKOUT MOUSE; LIPID DIET; LIPOGENESIS; LIPOLYSIS; MOUSE; NONHUMAN; PROTEIN INTERACTION; UPREGULATION;

ACUTE DISEASE; ADIPOGENESIS; ADIPOSE TISSUE; ANIMALS; BIOLOGICAL MARKERS; CITRIC ACID CYCLE; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; GENE EXPRESSION; IMMUNITY, INNATE; INFLAMMATION; INSULIN RESISTANCE; INTERLEUKIN-1; LIPOGENESIS; MACROPHAGES; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; MICROARRAY ANALYSIS; OBESITY; PHENOTYPE; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTOME; UP-REGULATION;

MUS;

EID: 84876786623     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2012.04.012     Document Type: Article

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