Dysfunctional cardiac mitochondrial bioenergetic, lipidomic, and signaling in a murine model of Barth syndrome

Journal of Lipid Research

Volumn 54, Issue 5, 2013, Pages 1312-1325

  Kiebish, Michael A ^a,d   Yang, Kui ^a   Liu, Xinping ^a   Mancuso, David J ^a   Guan, Shaoping ^a   Zhao, Zhongdan ^a   Sims, Harold F ^a   Cerqua, Rebekah ^a   Cade, W Todd ^a   Han, Xianlin ^a,e   Gross, Richard W ^a,b,c  

^a Washington University   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY   (United States)

^d Berg Diagnostics   (United States)

^e BURNHAM INSTITUTE   (United States)

Author keywords

Cardiolipin; Cardiolipin synthase; Electron transport chain; Lipidome; Mitochondria; Phospholipase; Tafazzin; Transgenic

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; CALCIUM INDEPENDENT PHOSPHOLIPASE A2; CALCIUM INDEPENDENT PHOSPHOLIPASE A2 GAMMA; CARDIOLIPIN; CARDIOPILIN SYNTHASE; CHOLINE; CYTOCHROME C OXIDASE; DILYSOCARDIOLIPIN; DOCOSAHEXAENOIC ACID; DOXYCYCLINE; GLUTAMIC ACID; HYDROXYICOSATETRAENOIC ACID; LINOLEIC ACID; MONOLYSOCARDIOLIPIN; PEPTIDES AND PROTEINS; PHOSPHATIDYLETHANOLAMINE; PROSTANOID; SYNTHETASE; TAFAZZIN; TRANSCRIPTOME; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARTH SYNDROME; BIOENERGY; CONTROLLED STUDY; DISEASE MODEL; ENZYME ACTIVITY; FATTY ACID OXIDATION; FEMALE; HEART HEMODYNAMICS; HEART MITOCHONDRION; INTRACELLULAR SIGNALING; LIPIDOMICS; LOSS OF FUNCTION MUTATION; MALE; METABOLITE; MITOCHONDRIAL RESPIRATION; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BARTH SYNDROME; CARDIOLIPINS; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; LIPIDS; MALE; MEMBRANE PROTEINS; MICE; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANES; SIGNAL TRANSDUCTION; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 84876784708     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M034728     Document Type: Article

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