Impaired cardiac reserve and severely diminished skeletal muscle o 2 utilization mediate exercise intolerance in barth syndrome

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 5, 2011, Pages

  Spencer, Carolyn T ^a   Byrne, Barry J ^c   Bryant, Randall M ^c   Margossian, Renee ^b   Maisenbacher, Melissa ^d   Breitenger, Petar ^c   Benni, Paul B ^e   Redfearn, Sharon ^c   Marcus, Edward ^b   Cade, W Todd ^f  

^a EAST CAROLINA UNIVERSITY   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c Congential Heart Center ^*  (United States)

^d UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^e CAS Medical Systems Incorporated   (United States)

^f WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiolipin; Cardiomyopathy; Congenital; Mitochondria

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ADOLESCENT; ADULT; ARTICLE; BARTH SYNDROME; BICYCLE ERGOMETER; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; EXERCISE TOLERANCE; HEART EJECTION FRACTION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE OXYGEN CONSUMPTION; HEART RATE; HUMAN; NEAR INFRARED SPECTROSCOPY; OXYGEN SATURATION; PRIORITY JOURNAL; SCHOOL CHILD; SKELETAL MUSCLE; VASTUS LATERALIS MUSCLE;

ADOLESCENT; ADRENERGIC BETA-ANTAGONISTS; ANALYSIS OF VARIANCE; BARTH SYNDROME; BIOLOGICAL MARKERS; BLOOD PRESSURE; CARDIOMYOPATHY, DILATED; CASE-CONTROL STUDIES; CHILD; CROSS-SECTIONAL STUDIES; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; EXERCISE TEST; EXERCISE TOLERANCE; HEART RATE; HEMOGLOBINS; HUMANS; MALE; MUSCLE CONTRACTION; OXYGEN; OXYGEN CONSUMPTION; QUADRICEPS MUSCLE; RESPIRATORY MECHANICS; SPECTROSCOPY, NEAR-INFRARED; VENTRICULAR FUNCTION, LEFT; YOUNG ADULT;

EID: 80355129941     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00479.2010     Document Type: Article

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