메뉴 건너뛰기




Volumn 19, Issue 8, 2013, Pages 1430-1438

The immunohistochemical assessment of HPV related adenocarcinoma: Pathologic and clinical prognostic significance

Author keywords

Adenosquamous carcinoma; Cervical adenocarcinoma; HPV; Immunohistochemistry

Indexed keywords

BIOLOGICAL MARKER; CAPSID PROTEIN; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; PROSTAGLANDIN SYNTHASE; PROTEIN P16; PROTEIN P53;

EID: 84876734231     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161213804805496     Document Type: Article
Times cited : (3)

References (58)
  • 1
    • 0029870831 scopus 로고    scopus 로고
    • The continuing increase in adenocarcinoma of the uterine cervix: A birth cohort phenomenon
    • Zheng T, Holford TR, Ma Z, et al. The continuing increase in adenocarcinoma of the uterine cervix: a birth cohort phenomenon. Int J Epidemiol 1996; 25: 252-8.
    • (1996) Int J Epidemiol , vol.25 , pp. 252-258
    • Zheng, T.1    Holford, T.R.2    Ma, Z.3
  • 2
    • 0033838644 scopus 로고    scopus 로고
    • The rising incidence of adenocarcinoma relative to squamous cell carcinoma of the uterine cervix in the United States-a 24-year population-based study
    • Smith HO, Tiffany MF, Qualls CR, Key CR. The rising incidence of adenocarcinoma relative to squamous cell carcinoma of the uterine cervix in the United States-a 24-year population-based study. Gynecol Oncol 2000; 78: 97-105.
    • (2000) Gynecol Oncol , vol.78 , pp. 97-105
    • Smith, H.O.1    Tiffany, M.F.2    Qualls, C.R.3    Key, C.R.4
  • 3
    • 3042719735 scopus 로고    scopus 로고
    • Detection of human papillomavirus DNA and expression of p16, Rb, and p53 proteins in small cell carcinomas of the uterine cervix
    • Wang HL, Lu DW. Detection of human papillomavirus DNA and expression of p16, Rb, and p53 proteins in small cell carcinomas of the uterine cervix. Am J Surg Pathol 2004; 28: 901-8.
    • (2004) Am J Surg Pathol , vol.28 , pp. 901-908
    • Wang, H.L.1    Lu, D.W.2
  • 4
    • 84863593922 scopus 로고    scopus 로고
    • Carcinoma and Other Tumors of the Cervix
    • In: Kurman RJ, Ellenson LH, Ronnett BM. Eds, 6th ed. Springer Science-Business Media, LLC
    • Witkiewicz AK, Wright TC, Ferenczy A, et al. Carcinoma and Other Tumors of the Cervix. In: Kurman RJ, Ellenson LH, Ronnett BM. Eds. Blaustein's Pathology of the Female Genital Tract. 6th ed. Springer Science-Business Media, LLC 2011; pp.273-303.
    • (2011) Blaustein's Pathology of the Female Genital Tract , pp. 273-303
    • Witkiewicz, A.K.1    Wright, T.C.2    Ferenczy, A.3
  • 5
    • 0033815503 scopus 로고    scopus 로고
    • Prevalence of human papillomavirus DNA in different histological subtypes of cervical adenocarcinoma
    • Pirog EC, Kleter B, Olgac S, et al. Prevalence of human papillomavirus DNA in different histological subtypes of cervical adenocarcinoma. Am J Pathol 2000; 157: 1055-62.
    • (2000) Am J Pathol , vol.157 , pp. 1055-1062
    • Pirog, E.C.1    Kleter, B.2    Olgac, S.3
  • 7
    • 33644764973 scopus 로고    scopus 로고
    • Worldwide human papillomavirus etiology of cervical adenocarcinoma and its cofactors: Implications for screening and prevention
    • Castellsague X, Diaz M, de Sanjose S, et al. Worldwide human papillomavirus etiology of cervical adenocarcinoma and its cofactors: implications for screening and prevention. J Natl Cancer Inst 2006; 98: 303-15.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 303-315
    • Castellsague, X.1    Diaz, M.2    de Sanjose, S.3
  • 8
    • 78149309466 scopus 로고    scopus 로고
    • Absence of high-risk human papillomavirus (HPV) detection in endocervical adenocarcinoma with gastric morphology and phenotype
    • Kusanagi Y, Kojima A, Mikami Y, et al. Absence of high-risk human papillomavirus (HPV) detection in endocervical adenocarcinoma with gastric morphology and phenotype. Am J Pathol 2010; 177: 2169-75.
    • (2010) Am J Pathol , vol.177 , pp. 2169-2175
    • Kusanagi, Y.1    Kojima, A.2    Mikami, Y.3
  • 9
    • 49549104181 scopus 로고    scopus 로고
    • A review of cross-protection against oncogenic HPV by an HPV-16/18 AS04-adjuvanted cervical cancer vaccine: Importance of virological and clinical endpoints and implications for mass vaccination in cervical cancer prevention
    • Jenkins D. A review of cross-protection against oncogenic HPV by an HPV-16/18 AS04-adjuvanted cervical cancer vaccine: Importance of virological and clinical endpoints and implications for mass vaccination in cervical cancer prevention. Gynecol Oncol 2008; 110: S18-S25.
    • (2008) Gynecol Oncol , vol.110
    • Jenkins, D.1
  • 10
    • 77949590549 scopus 로고    scopus 로고
    • Unusual endocervical adenocarcinomas: An immunohistochemical analysis with molecular detection of human papillomavirus
    • Park KJ, Lamb C, Oliva E, Soslow RA, Kiyokawa T. Unusual endocervical adenocarcinomas: an immunohistochemical analysis with molecular detection of human papillomavirus. Mod Pathol 2008; 21: 217A.
    • (2008) Mod Pathol , vol.21
    • Park, K.J.1    Lamb, C.2    Oliva, E.3    Soslow, R.A.4    Kiyokawa, T.5
  • 11
    • 80052415423 scopus 로고    scopus 로고
    • Relationship of HPVL1 and p16 expression with different cervical lesions
    • Wu H, Shi H, Kong L. Relationship of HPVL1 and p16 expression with different cervical lesions. Sci Res Essays 2011; 6: 3724-8.
    • (2011) Sci Res Essays , vol.6 , pp. 3724-3728
    • Wu, H.1    Shi, H.2    Kong, L.3
  • 12
    • 0037531418 scopus 로고    scopus 로고
    • P16 immunoreactivity may assist in the distinction between endometrial and endocervical adenocarcinoma
    • McCluggage WG, Jenkins D. P16 immunoreactivity may assist in the distinction between endometrial and endocervical adenocarcinoma. Int J Gynecol Pathol 2003; 22: 231-5.
    • (2003) Int J Gynecol Pathol , vol.22 , pp. 231-235
    • McCluggage, W.G.1    Jenkins, D.2
  • 13
    • 77950519536 scopus 로고    scopus 로고
    • Cyclin D1 immunoreactivity in normal endocervix and diagnostic value in reactive and neoplastic endocervical lesions
    • Little L, Stewart CJR. Cyclin D1 immunoreactivity in normal endocervix and diagnostic value in reactive and neoplastic endocervical lesions. Modern Pathol 2010; 23: 611-8.
    • (2010) Modern Pathol , vol.23 , pp. 611-618
    • Little, L.1    Stewart, C.J.R.2
  • 14
    • 79954576306 scopus 로고    scopus 로고
    • Correlation between invasive pattern and immunophenotypic alterations in endocervical adenocarcinoma
    • Stewart CJR, Crook ML, Little L, Louwen K. Correlation between invasive pattern and immunophenotypic alterations in endocervical adenocarcinoma. Histopath 2011; 58: 720-8.
    • (2011) Histopath , vol.58 , pp. 720-728
    • Stewart, C.J.R.1    Crook, M.L.2    Little, L.3    Louwen, K.4
  • 15
    • 34248594717 scopus 로고    scopus 로고
    • Prognosis of adenocarcinoma of the uterine cervix: P53 expression correlates with higher incidence of mortality
    • Baalbergen A, Ewing-Graham PC, Eijkemans MJ, Helmerhorst TJM. Prognosis of adenocarcinoma of the uterine cervix: p53 expression correlates with higher incidence of mortality. Int J Cancer 2007; 121: 106-10.
    • (2007) Int J Cancer , vol.121 , pp. 106-110
    • Baalbergen, A.1    Ewing-Graham, P.C.2    Eijkemans, M.J.3    Helmerhorst, T.J.M.4
  • 16
    • 0035316185 scopus 로고    scopus 로고
    • Human Papillomavirus 16/18 expression of endocervical glandular lesions: Relationship with p53 and MIB-1 expressions
    • Yoon HK, Kim YJ, Kang MS. Human Papillomavirus 16/18 expression of endocervical glandular lesions: relationship with p53 and MIB-1 expressions. J Korean Med Sci 2001; 16: 169-74.
    • (2001) J Korean Med Sci , vol.16 , pp. 169-174
    • Yoon, H.K.1    Kim, Y.J.2    Kang, M.S.3
  • 17
    • 0342547093 scopus 로고    scopus 로고
    • Immunohistochemical detection of p53 and bcl-2 proteins in neoplastic and non-neoplastic endocervical glandular lesions
    • McCluggage G, McBride H, Maxwell P, Bharucha H. Immunohistochemical detection of p53 and bcl-2 proteins in neoplastic and non-neoplastic endocervical glandular lesions. Int J Gynecol Pathol 1997; 16: 22-7.
    • (1997) Int J Gynecol Pathol , vol.16 , pp. 22-27
    • McCluggage, G.1    McBride, H.2    Maxwell, P.3    Bharucha, H.4
  • 18
    • 80053148870 scopus 로고    scopus 로고
    • Epidermal growth factor receptor as a biomarker for cervical cancer
    • Soonthornthum T, Arias-Pulido H, Joste N, et al. Epidermal growth factor receptor as a biomarker for cervical cancer. Ann Oncol 2011; 22(10): 2166-78.
    • (2011) Ann Oncol , vol.22 , Issue.10 , pp. 2166-2178
    • Soonthornthum, T.1    Arias-Pulido, H.2    Joste, N.3
  • 19
    • 79960839126 scopus 로고    scopus 로고
    • EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target
    • Iida K, Nakayama K, Rahman MT, et al. EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target. British J Cancer 2011; 105: 420-7.
    • (2011) British J Cancer , vol.105 , pp. 420-427
    • Iida, K.1    Nakayama, K.2    Rahman, M.T.3
  • 20
    • 34250870226 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and epidermal growth factor receptor expressions in different histological subtypes of cervical carcinomas
    • Baltazar F, Filho AL, Pinheiro C, et al. Cyclooxygenase-2 and epidermal growth factor receptor expressions in different histological subtypes of cervical carcinomas. Int J Gynecol Pathol 2007; 26: 235-41.
    • (2007) Int J Gynecol Pathol , vol.26 , pp. 235-241
    • Baltazar, F.1    Filho, A.L.2    Pinheiro, C.3
  • 21
    • 0035126879 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is overexpressed in human cervical cancer
    • Kulkarni S, Rader JS, Zhang F, et al. Cyclooxygenase-2 is overexpressed in human cervical cancer. Clin Cancer Res 2001; 7: 429-34.
    • (2001) Clin Cancer Res , vol.7 , pp. 429-434
    • Kulkarni, S.1    Rader, J.S.2    Zhang, F.3
  • 22
    • 0037342351 scopus 로고    scopus 로고
    • High cyclooxygenase-2 expression in cervical adenocarcinomas
    • Chen YJ, Wang LS, Wang PH, et al. High cyclooxygenase-2 expression in cervical adenocarcinomas. Gynecol Oncol 2003; 88: 379-85.
    • (2003) Gynecol Oncol , vol.88 , pp. 379-385
    • Chen, Y.J.1    Wang, L.S.2    Wang, P.H.3
  • 23
    • 7644239791 scopus 로고    scopus 로고
    • Correlation of immunochemical detection of HPV L1 capsid protein in pap smears with regression of high-risk HPV positive mild/moderate dysplasia
    • Griesser H, Sander H, Hilfrich R, Moser B, Schenck U. Correlation of immunochemical detection of HPV L1 capsid protein in pap smears with regression of high-risk HPV positive mild/moderate dysplasia. Anal Quant Cytol Histol 2004; 26: 241-5.
    • (2004) Anal Quant Cytol Histol , vol.26 , pp. 241-245
    • Griesser, H.1    Sander, H.2    Hilfrich, R.3    Moser, B.4    Schenck, U.5
  • 24
    • 0031915998 scopus 로고    scopus 로고
    • Prognostic and predictive factors in breast cancer by immunohistochemical analysis
    • Allred DC, Harvey JM, Berardo M, Clark GM. Prognostic and predictive factors in breast cancer by immunohistochemical analysis, Mod Pathol 1998; 11: 155-68.
    • (1998) Mod Pathol , vol.11 , pp. 155-168
    • Allred, D.C.1    Harvey, J.M.2    Berardo, M.3    Clark, G.M.4
  • 25
    • 1542724882 scopus 로고    scopus 로고
    • Quantitation in immunohistology: Fact or fiction? A discussion of variables that influence results
    • Leong AS. Quantitation in immunohistology: fact or fiction? A discussion of variables that influence results. Appl Immunohistochem Mol Morphol 2004; 12:1-7.
    • (2004) Appl Immunohistochem Mol Morphol , vol.12 , pp. 1-7
    • Leong, A.S.1
  • 26
    • 77950507520 scopus 로고    scopus 로고
    • Diagnostic value of p16INK4A, Ki-67, and human papillomavirus L1 capsid protein immunochemical staining on cell blocks from residual liquid-based gynecologic cytology specimens
    • Yu L, Wang L, Zhong J, Chen S. Diagnostic value of p16INK4A, Ki-67, and human papillomavirus L1 capsid protein immunochemical staining on cell blocks from residual liquid-based gynecologic cytology specimens. Cancer Cytopathol 2010; 118: 47-55.
    • (2010) Cancer Cytopathol , vol.118 , pp. 47-55
    • Yu, L.1    Wang, L.2    Zhong, J.3    Chen, S.4
  • 27
    • 0037289732 scopus 로고    scopus 로고
    • 16INK4a is a useful marker for the diagnosis of adenocarcinoma of the cervix uteri and its precursors: An immunohistochemical study with immunocytochemical correlations
    • Negri G, Egarter-Vigl E, Kasal A, Romano F, Haitel A, Mian C. 16INK4a is a useful marker for the diagnosis of adenocarcinoma of the cervix uteri and its precursors: an immunohistochemical study with immunocytochemical correlations. Am J Surg Pathol 2003; 27: 187-93.
    • (2003) Am J Surg Pathol , vol.27 , pp. 187-193
    • Negri, G.1    Egarter-Vigl, E.2    Kasal, A.3    Romano, F.4    Haitel, A.5    Mian, C.6
  • 28
    • 0141569547 scopus 로고    scopus 로고
    • Correlation of p16INK4A overexpression with human papillomavirus infection in cervical adenocarcinomas
    • Ishikawa M, Fujii T, Masumoto N, et al. Correlation of p16INK4A overexpression with human papillomavirus infection in cervical adenocarcinomas. Int J Gynecol Pathol 2003; 22: 378-85.
    • (2003) Int J Gynecol Pathol , vol.22 , pp. 378-385
    • Ishikawa, M.1    Fujii, T.2    Masumoto, N.3
  • 29
    • 33845920618 scopus 로고    scopus 로고
    • Utility of p16INK4a, CEA, Ki-67, P53 and ER/PR in the differential diagnosis of benign, premalignant, and malignant glandular lesions of the uterine cervix and their relationship with Silverberg scoring system for endocervical glandular lesions
    • Liang J, Mittal KR, Wei JJ, Yee H, Chiriboga L, Shukla P. Utility of p16INK4a, CEA, Ki-67, P53 and ER/PR in the differential diagnosis of benign, premalignant, and malignant glandular lesions of the uterine cervix and their relationship with Silverberg scoring system for endocervical glandular lesions. Int J Gynecol Pathol 2007; 26: 71-5.
    • (2007) Int J Gynecol Pathol , vol.26 , pp. 71-75
    • Liang, J.1    Mittal, K.R.2    Wei, J.J.3    Yee, H.4    Chiriboga, L.5    Shukla, P.6
  • 30
    • 38849201730 scopus 로고    scopus 로고
    • Expression of p16INK4a and MIB-1 in relation to histopathology and HPV types in cervical adenocarcinoma
    • Muller S, Flores-Staino C, Skyldberg B, et al. Expression of p16INK4a and MIB-1 in relation to histopathology and HPV types in cervical adenocarcinoma. Int J Oncol 2008; 32: 333-40.
    • (2008) Int J Oncol , vol.32 , pp. 333-340
    • Muller, S.1    Flores-Staino, C.2    Skyldberg, B.3
  • 31
    • 79958862642 scopus 로고    scopus 로고
    • Usefulness of p16ink4a, ProEX C, and Ki-67 for the diagnosis of glandular dysplasia and adenocarcinoma of the cervix uteri
    • Negri G, Bellisano G, Carico E, et al. Usefulness of p16ink4a, ProEX C, and Ki-67 for the diagnosis of glandular dysplasia and adenocarcinoma of the cervix uteri. Int J Gynecol Pathol 2011; 30: 407-13.
    • (2011) Int J Gynecol Pathol , vol.30 , pp. 407-413
    • Negri, G.1    Bellisano, G.2    Carico, E.3
  • 32
    • 33646154215 scopus 로고    scopus 로고
    • Purification and characterisation of the E7 oncoproteins of the high-risk human papillomavirus types 16 and 18
    • Fiedler M, Campo-Fernández B, Laich A, et al. Purification and characterisation of the E7 oncoproteins of the high-risk human papillomavirus types 16 and 18. J Virol Methods 2006; 134: 30-5.
    • (2006) J Virol Methods , vol.134 , pp. 30-35
    • Fiedler, M.1    Campo-Fernández, B.2    Laich, A.3
  • 33
    • 65449133543 scopus 로고    scopus 로고
    • Scoring mechanisms of p16INK4a immunohistochemistry based on either independent nucleic stain or mixed cytoplasmic with nucleic expression can significantly signal to distinguish between endocervical and endometrial adenocarcinomas in a tissue microarray study
    • Koo CL, Kok LF, Lee MY, et al. Scoring mechanisms of p16INK4a immunohistochemistry based on either independent nucleic stain or mixed cytoplasmic with nucleic expression can significantly signal to distinguish between endocervical and endometrial adenocarcinomas in a tissue microarray study. J Translat Med 2009; 7: 25.
    • (2009) J Translat Med , vol.7 , pp. 25
    • Koo, C.L.1    Kok, L.F.2    Lee, M.Y.3
  • 34
    • 0036742794 scopus 로고    scopus 로고
    • Human papillomaviruses, expression of p16, and early endocervical glandular neoplasia
    • Riethdorf L, Riethdorf S, Lee KR, Cviko A, Löning T, Crum CP. Human papillomaviruses, expression of p16, and early endocervical glandular neoplasia. Hum Pathol 2002; 33: 899-904.
    • (2002) Hum Pathol , vol.33 , pp. 899-904
    • Riethdorf, L.1    Riethdorf, S.2    Lee, K.R.3    Cviko, A.4    Löning, T.5    Crum, C.P.6
  • 35
    • 12144251609 scopus 로고    scopus 로고
    • p16INK4A positivity in benign, premalignant and malignant cervical glandular lesions: A potential diagnostic problem
    • Murphy N, Heffron CC, King B, et al. p16INK4A positivity in benign, premalignant and malignant cervical glandular lesions: a potential diagnostic problem. Virchows Arch 2004; 445: 610-5.
    • (2004) Virchows Arch , vol.445 , pp. 610-615
    • Murphy, N.1    Heffron, C.C.2    King, B.3
  • 36
    • 68349157260 scopus 로고    scopus 로고
    • p16 as a diagnostic marker of cervical neoplasia: A tissue microarray study of 796 archival specimens
    • Lesnikova I, Lidang M, Hamilton-Dutoit S, Koch J. p16 as a diagnostic marker of cervical neoplasia: a tissue microarray study of 796 archival specimens. Diagnostic Pathology 2009; 4: 22-8.
    • (2009) Diagnostic Pathology , vol.4 , pp. 22-28
    • Lesnikova, I.1    Lidang, M.2    Hamilton-Dutoit, S.3    Koch, J.4
  • 37
    • 56149103682 scopus 로고    scopus 로고
    • p16ink4a and HPV L1 immunohistochemistry is helpful forestimating the behavior of low-grade dysplastic lesions of the cervix uteri
    • Negri G, Bellisano G, Zannoni GF, et al. p16ink4a and HPV L1 immunohistochemistry is helpful forestimating the behavior of low-grade dysplastic lesions of the cervix uteri. Am J Surg Pathol 2008; 32: 1715-20.
    • (2008) Am J Surg Pathol , vol.32 , pp. 1715-1720
    • Negri, G.1    Bellisano, G.2    Zannoni, G.F.3
  • 38
    • 14744285753 scopus 로고    scopus 로고
    • The papillomavirus life cycle
    • Doorbar J. The papillomavirus life cycle. J Clin Virol 2005; 32: S7-15.
    • (2005) J Clin Virol , vol.32 , pp. 7-15
    • Doorbar, J.1
  • 39
    • 0030944884 scopus 로고    scopus 로고
    • Immunohistochemical staining for Ki-67 antigen, carcinoembryonic antigen, and p53 in the differential diagnosis of glanmdular lesions of the cervix
    • Cina SJ, Richardson MS, Austin RM, Kurman RJ. Immunohistochemical staining for Ki-67 antigen, carcinoembryonic antigen, and p53 in the differential diagnosis of glanmdular lesions of the cervix. Mod Pathol 1997; 10: 176-80.
    • (1997) Mod Pathol , vol.10 , pp. 176-180
    • Cina, S.J.1    Richardson, M.S.2    Austin, R.M.3    Kurman, R.J.4
  • 40
    • 0034007705 scopus 로고    scopus 로고
    • The possible role of p53 and bcl-2 expression in cervical carcinomas and their premalignant lesions
    • Dimitrakakis C, Kymionis G, Diakomanolis E, et al. The possible role of p53 and bcl-2 expression in cervical carcinomas and their premalignant lesions. Gynecol Oncol 2000; 77: 129-36.
    • (2000) Gynecol Oncol , vol.77 , pp. 129-136
    • Dimitrakakis, C.1    Kymionis, G.2    Diakomanolis, E.3
  • 41
    • 0036080759 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in adenocarcinomas of the uterine cervix and its relation to angiogenesis and p53 and c-erbB-2 protein expression
    • Lee JS, Kim HS, Jung JJ, Lee MC, Park CS. Expression of vascular endothelial growth factor in adenocarcinomas of the uterine cervix and its relation to angiogenesis and p53 and c-erbB-2 protein expression. Gynecol Oncol 2002; 85: 469-75.
    • (2002) Gynecol Oncol , vol.85 , pp. 469-475
    • Lee, J.S.1    Kim, H.S.2    Jung, J.J.3    Lee, M.C.4    Park, C.S.5
  • 42
    • 0742324872 scopus 로고    scopus 로고
    • Correlation between responsiveness of neoadjuvant chemotherapy and apoptosis-associated proteins for cervical adenocarcinoma
    • Saito T, Takehara M, Tanaka R, et al. Correlation between responsiveness of neoadjuvant chemotherapy and apoptosis-associated proteins for cervical adenocarcinoma. Gynecol Oncol 2004; 92: 284-92.
    • (2004) Gynecol Oncol , vol.92 , pp. 284-292
    • Saito, T.1    Takehara, M.2    Tanaka, R.3
  • 43
    • 0036221471 scopus 로고    scopus 로고
    • The causal relation between human papilloma virus and cervical cancer
    • Bosch FX, Lorincz A, Munoz N, et al. The causal relation between human papilloma virus and cervical cancer. J Clin pathol 2002; 55: 244-65.
    • (2002) J Clin pathol , vol.55 , pp. 244-265
    • Bosch, F.X.1    Lorincz, A.2    Munoz, N.3
  • 44
    • 0026692067 scopus 로고
    • Epidermal growth factor receptor expression and the presence of human papillomavirus in cervical squamous intraepithelial lesions
    • Chapman WB, lorincz AT, Willet GD, et al. Epidermal growth factor receptor expression and the presence of human papillomavirus in cervical squamous intraepithelial lesions. Int J gynecol Pathol 1992; 11: 221-26.
    • (1992) Int J gynecol Pathol , vol.11 , pp. 221-226
    • Chapman, W.B.1    lorincz, A.T.2    Willet, G.D.3
  • 45
    • 0030817148 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor and human papillomavirus e6/E7 proteins in cervical carcinoma cells
    • Hu G, Liu W, Mendelsohn J, et al. Expression of epidermal growth factor receptor and human papillomavirus e6/E7 proteins in cervical carcinoma cells. J Natl Cancer Inst 1997; 89: 1271-76.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1271-1276
    • Hu, G.1    Liu, W.2    Mendelsohn, J.3
  • 46
    • 0035328577 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes
    • Akerman GS, Tolleson WH, Brown KL, et al. Human papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes. Cancer res 2001; 61: 3837-43.
    • (2001) Cancer res , vol.61 , pp. 3837-3843
    • Akerman, G.S.1    Tolleson, W.H.2    Brown, K.L.3
  • 47
    • 17844396023 scopus 로고    scopus 로고
    • HPV 16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes
    • Zhang B, Srirangam A, Potter DA, Roman A. HPV 16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes. Oncogene 2005; 24: 2585-88.
    • (2005) Oncogene , vol.24 , pp. 2585-2588
    • Zhang, B.1    Srirangam, A.2    Potter, D.A.3    Roman, A.4
  • 48
    • 0033042754 scopus 로고    scopus 로고
    • Oncogene alterations in carcinomas of the uterine cervix: Overexpression of the epidermal growth factor is associated with poor prognosis
    • Kersemaekers AM, Fleuren GJ, Kenter GG, et al. Oncogene alterations in carcinomas of the uterine cervix: overexpression of the epidermal growth factor is associated with poor prognosis. Clin Cancer Res 1999; 5: 577-86.
    • (1999) Clin Cancer Res , vol.5 , pp. 577-586
    • Kersemaekers, A.M.1    Fleuren, G.J.2    Kenter, G.G.3
  • 49
    • 67651093726 scopus 로고    scopus 로고
    • Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma
    • Longatto-Filho A, Pinheiro C, Martinho O, et al. Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma. BMC Cancer 2009; 9:212.
    • (2009) BMC Cancer , vol.9 , pp. 212
    • Longatto-Filho, A.1    Pinheiro, C.2    Martinho, O.3
  • 52
    • 0030002363 scopus 로고    scopus 로고
    • Cyclin D1 gene expression in human cervical nmeoplasia
    • Nichols GE, Williams ME, Gaffey MJ, et al. Cyclin D1 gene expression in human cervical nmeoplasia. Mod Pathol 1996; 9: 418-25.
    • (1996) Mod Pathol , vol.9 , pp. 418-425
    • Nichols, G.E.1    Williams, M.E.2    Gaffey, M.J.3
  • 53
    • 0032932656 scopus 로고    scopus 로고
    • Aberrant expression of the cell cycle associated proteins TP53, MDM2, p21, p27, cdk4, cyclin D1, RB, and EGFR in cervical carcinomas
    • Skomedal H, Kristensen GB, Lie AK, et al. Aberrant expression of the cell cycle associated proteins TP53, MDM2, p21, p27, cdk4, cyclin D1, RB, and EGFR in cervical carcinomas. Gynecol Oncol 1999; 73: 223-28.
    • (1999) Gynecol Oncol , vol.73 , pp. 223-228
    • Skomedal, H.1    Kristensen, G.B.2    Lie, A.K.3
  • 54
    • 0031964379 scopus 로고    scopus 로고
    • Etiological involvement of oncogenic human papillomavirus in tonsillar squamous cell carcinomas lacking retinoblastoma cell cycle control
    • Andl T, Khan T, Pfuhl A, et al. Etiological involvement of oncogenic human papillomavirus in tonsillar squamous cell carcinomas lacking retinoblastoma cell cycle control. Cancer Res 1998; 58: 5-13.
    • (1998) Cancer Res , vol.58 , pp. 5-13
    • Andl, T.1    Khan, T.2    Pfuhl, A.3
  • 55
    • 0347596814 scopus 로고    scopus 로고
    • The expression of key cell cycle markers and presence of human papillomavirus in squamous cell carcinoma of the tonsil
    • Li W, Thompson CH, Cossart YE, et al. The expression of key cell cycle markers and presence of human papillomavirus in squamous cell carcinoma of the tonsil. Head Neck 2004; 26: 1-9.
    • (2004) Head Neck , vol.26 , pp. 1-9
    • Li, W.1    Thompson, C.H.2    Cossart, Y.E.3
  • 56
    • 84855437586 scopus 로고    scopus 로고
    • Immunohistochemical assessment of p16, COX-2, and EGFR in HPV-positive cervical squamlous intraepithelial lesions
    • Balan R, Simion N, Giusca SE, et al. Immunohistochemical assessment of p16, COX-2, and EGFR in HPV-positive cervical squamlous intraepithelial lesions. Rom J Morphol Embryol 2011; 52: 1187-94.
    • (2011) Rom J Morphol Embryol , vol.52 , pp. 1187-1194
    • Balan, R.1    Simion, N.2    Giusca, S.E.3
  • 57
    • 33646024319 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 expression is correlated with suppressed antitumor immunity in cervical adenocarcinomas
    • Chen TH, Fukuhara K, Mandai M, et al. Increased cyclooxygenase-2 expression is correlated with suppressed antitumor immunity in cervical adenocarcinomas. Int J Gynecol Cancer 2006; 16: 772-79.
    • (2006) Int J Gynecol Cancer , vol.16 , pp. 772-779
    • Chen, T.H.1    Fukuhara, K.2    Mandai, M.3
  • 58
    • 0037344480 scopus 로고    scopus 로고
    • Immunocytochemical detection of HPV high-risk type L1 capsid proteins in LSIL and HSIL as compared with detection of HPV L1 DNA
    • Melsheimer P, Kaul S, Dobeck S, Bastert G. Immunocytochemical detection of HPV high-risk type L1 capsid proteins in LSIL and HSIL as compared with detection of HPV L1 DNA. Acta Cytol 2003; 47:124-28.
    • (2003) Acta Cytol , vol.47 , pp. 124-128
    • Melsheimer, P.1    Kaul, S.2    Dobeck, S.3    Bastert, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.