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Volumn 22, Issue 4, 2003, Pages 378-385

Correlation of p16INK4A overexpression with human papillomavirus infection in cervical adenocarcinomas

Author keywords

Adenocarcinoma; Human papillomavirus; P16INK4A; Uterine cervix

Indexed keywords

PROTEIN P16; VIRUS DNA; DIAGNOSTIC AGENT; MONOCLONAL ANTIBODY; PROTEIN P16INK4A; TUMOR MARKER;

EID: 0141569547     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pgp.0000092135.88121.1f     Document Type: Article
Times cited : (54)

References (44)
  • 1
    • 0029021302 scopus 로고
    • The major E6/E7 transcript of HPV-16 in exfoliated cells from cervical neoplasia patients
    • Fujii T, Tsukazaki K, Kiguchi K, et al. The major E6/E7 transcript of HPV-16 in exfoliated cells from cervical neoplasia patients. Gynecol Oncol 1995;58:210-5.
    • (1995) Gynecol Oncol , vol.58 , pp. 210-215
    • Fujii, T.1    Tsukazaki, K.2    Kiguchi, K.3
  • 2
    • 0036323469 scopus 로고    scopus 로고
    • Frequent detection of human papilloma viruses in cervical dysplasia by PCR single-strand DNA-conformational polymorphism analysis
    • Nakagawa H, Sugano K, Fujii T, et al. Frequent detection of human papilloma viruses in cervical dysplasia by PCR single-strand DNA-conformational polymorphism analysis. Anticancer Res 2002;22:1655-60.
    • (2002) Anticancer Res , vol.22 , pp. 1655-1660
    • Nakagawa, H.1    Sugano, K.2    Fujii, T.3
  • 3
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993;366:704-7.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 4
    • 0028034775 scopus 로고
    • Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retino-blastoma susceptibility gene product pRb
    • Li Y, Nichols MA, Shay JW, et al. Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retino-blastoma susceptibility gene product pRb. Cancer Res 1994;54:6078-82.
    • (1994) Cancer Res , vol.54 , pp. 6078-6082
    • Li, Y.1    Nichols, M.A.2    Shay, J.W.3
  • 5
    • 0034028836 scopus 로고    scopus 로고
    • Tumor suppressors and oncogenes in cellular senescence
    • Bringold F, Serrano M. Tumor suppressors and oncogenes in cellular senescence. Exp Gerontol 2000;35:317-29.
    • (2000) Exp Gerontol , vol.35 , pp. 317-329
    • Bringold, F.1    Serrano, M.2
  • 6
    • 0028869884 scopus 로고
    • Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product
    • Parry D, Bates S, Mann DJ, et al. Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product. EMBO J 1995;14:503-11.
    • (1995) EMBO J , vol.14 , pp. 503-511
    • Parry, D.1    Bates, S.2    Mann, D.J.3
  • 7
    • 0029971843 scopus 로고    scopus 로고
    • Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: An immunohistochemical study
    • Sakaguchi M, Fujii Y, Hirabayashi H, et al. Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: an immunohistochemical study. Int J Cancer 1996;65:442-5.
    • (1996) Int J Cancer , vol.65 , pp. 442-445
    • Sakaguchi, M.1    Fujii, Y.2    Hirabayashi, H.3
  • 8
    • 0030960749 scopus 로고    scopus 로고
    • Induction of p16 during immortalization by HPV 16 and 18 and not during malignant transformation
    • Nakao Y, Yang X, Yokoyama M, et al. Induction of p16 during immortalization by HPV 16 and 18 and not during malignant transformation. Br J Cancer 1997;75:1410-6.
    • (1997) Br J Cancer , vol.75 , pp. 1410-1416
    • Nakao, Y.1    Yang, X.2    Yokoyama, M.3
  • 9
    • 0035871985 scopus 로고    scopus 로고
    • Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri
    • Klaes R, Friedrich T, Spitkovsky D, et al. Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Intl J Cancer 2001;92:276-84.
    • (2001) Intl J Cancer , vol.92 , pp. 276-284
    • Klaes, R.1    Friedrich, T.2    Spitkovsky, D.3
  • 10
    • 0035849309 scopus 로고    scopus 로고
    • Changing rates of adenocarcinoma and adenosquamous carcinoma of the cervix in England
    • Sasieni P, Adams J. Changing rates of adenocarcinoma and adenosquamous carcinoma of the cervix in England. Lancet 2001;357:1490-3.
    • (2001) Lancet , vol.357 , pp. 1490-1493
    • Sasieni, P.1    Adams, J.2
  • 11
    • 0035574831 scopus 로고    scopus 로고
    • Cervical cancer: The increasing incidence of adenocarcinoma and adenosquamous carcinoma in younger women
    • Liu S, Semenciw R, Mao Y. Cervical cancer: the increasing incidence of adenocarcinoma and adenosquamous carcinoma in younger women. CMAJ 2001;164:1151-2.
    • (2001) CMAJ , vol.164 , pp. 1151-1152
    • Liu, S.1    Semenciw, R.2    Mao, Y.3
  • 12
    • 18744391356 scopus 로고    scopus 로고
    • Multivariate analysis of histopathologic prognostic factors for invasive cervical cancer treated with radical hysterectomy and systematic retroperitoneal lymphadenectomy
    • Takeda N, Sakuragi N, Takeda M, et al. Multivariate analysis of histopathologic prognostic factors for invasive cervical cancer treated with radical hysterectomy and systematic retroperitoneal lymphadenectomy. Acta Obstet Gynecol Scand 2002;81:1144-51.
    • (2002) Acta Obstet Gynecol Scand , vol.81 , pp. 1144-1151
    • Takeda, N.1    Sakuragi, N.2    Takeda, M.3
  • 13
    • 0033830315 scopus 로고    scopus 로고
    • Prognosis and clinicopathological characteristics of Ib-IIb adenocarcinoma of the uterine cervix in patients who have had radical hysterectomy
    • Irie T, Kigawa J, Minagawa Y, et al. Prognosis and clinicopathological characteristics of Ib-IIb adenocarcinoma of the uterine cervix in patients who have had radical hysterectomy. Eur J Surg Oncol 2000;26:464-7.
    • (2000) Eur J Surg Oncol , vol.26 , pp. 464-467
    • Irie, T.1    Kigawa, J.2    Minagawa, Y.3
  • 14
    • 0032907421 scopus 로고    scopus 로고
    • Influence of histologic type and age on survival rates for invasive cervical carcinoma in Taiwan
    • Chen RJ, Lin YH, Chen CA, et al. Influence of histologic type and age on survival rates for invasive cervical carcinoma in Taiwan. Gynecol Oncol 1999;73:184-90.
    • (1999) Gynecol Oncol , vol.73 , pp. 184-190
    • Chen, R.J.1    Lin, Y.H.2    Chen, C.A.3
  • 15
    • 0025811207 scopus 로고
    • Simultaneous detection and typing of genital human papillomavirus DNA using the polymerase chain reaction
    • Fujinaga Y, Shimada M, Okazawa K, et al. Simultaneous detection and typing of genital human papillomavirus DNA using the polymerase chain reaction. J Gen Virol 1991;72:1039-44.
    • (1991) J Gen Virol , vol.72 , pp. 1039-1044
    • Fujinaga, Y.1    Shimada, M.2    Okazawa, K.3
  • 16
    • 0034042015 scopus 로고    scopus 로고
    • A new PCR-based assay amplifies the E6-E7 genes of most mucosal human papillomaviruses (HPV)
    • Sasagawa T, Minemoto Y, Basha W, et al. A new PCR-based assay amplifies the E6-E7 genes of most mucosal human papillomaviruses (HPV). Virus Res 2000;67:127-39.
    • (2000) Virus Res , vol.67 , pp. 127-139
    • Sasagawa, T.1    Minemoto, Y.2    Basha, W.3
  • 17
    • 0028940722 scopus 로고
    • Cell-cycle regulators and cancer
    • Kamb A. Cell-cycle regulators and cancer. Trends Genet 1995;11:136-40.
    • (1995) Trends Genet , vol.11 , pp. 136-140
    • Kamb, A.1
  • 18
    • 0028059330 scopus 로고
    • Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
    • Caldas C, Hahn SA, da Costa LT, et al. Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat Genet 1994;8:27-32.
    • (1994) Nat Genet , vol.8 , pp. 27-32
    • Caldas, C.1    Hahn, S.A.2    Da Costa, L.T.3
  • 19
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995;1:686-92.
    • (1995) Nat Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3
  • 20
    • 0029975913 scopus 로고    scopus 로고
    • Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity
    • Khleif SN, DeGregori J, Yee CL, et al. Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc Nat Acad Sciences USA 1996;93:4350-4.
    • (1996) Proc Nat Acad Sciences USA , vol.93 , pp. 4350-4354
    • Khleif, S.N.1    DeGregori, J.2    Yee, C.L.3
  • 21
    • 0032928267 scopus 로고    scopus 로고
    • Alteration of p16 and p15 genes in human uterine tumours
    • Nakashima R, Fujita M, Enomoto T, et al. Alteration of p16 and p15 genes in human uterine tumours. Br J Cancer 1999;80:458-67.
    • (1999) Br J Cancer , vol.80 , pp. 458-467
    • Nakashima, R.1    Fujita, M.2    Enomoto, T.3
  • 22
    • 0033000427 scopus 로고    scopus 로고
    • Detection of p16 gene alteration in cervical cancer using tissue microdissection and LOH study
    • Park JS, Dong SM, Kim HS, et al. Detection of p16 gene alteration in cervical cancer using tissue microdissection and LOH study. Cancer Lett 1999;136:101-8.
    • (1999) Cancer Lett , vol.136 , pp. 101-108
    • Park, J.S.1    Dong, S.M.2    Kim, H.S.3
  • 23
    • 0034146740 scopus 로고    scopus 로고
    • Alteration of the CDKN2/p16 gene is not required for HPV-positive uterine cervical cancer cell lines
    • Yoshinouchi M, Hongo A, Takamoto N, et al. Alteration of the CDKN2/p16 gene is not required for HPV-positive uterine cervical cancer cell lines. Intl J Oncol 2000;16:537-41.
    • (2000) Intl J Oncol , vol.16 , pp. 537-541
    • Yoshinouchi, M.1    Hongo, A.2    Takamoto, N.3
  • 24
    • 0032105506 scopus 로고    scopus 로고
    • Absence of p15INK4B and p16INK4A gene alterations in primary cervical carcinoma tissues and cell lines with human papillomavirus infection
    • Kim JW, Namkoong SE, Ryu SW, et al. Absence of p15INK4B and p16INK4A gene alterations in primary cervical carcinoma tissues and cell lines with human papillomavirus infection. Gynecol Oncol 1998;70:75-9.
    • (1998) Gynecol Oncol , vol.70 , pp. 75-79
    • Kim, J.W.1    Namkoong, S.E.2    Ryu, S.W.3
  • 25
    • 0032102219 scopus 로고    scopus 로고
    • The status of human papillomavirus and tumor suppressor genes p53 and p16 in carcinomas of uterine cervix from India
    • Munirajan AK, Kannan K, Bhuvarahamurthy V, et al. The status of human papillomavirus and tumor suppressor genes p53 and p16 in carcinomas of uterine cervix from India. Gynecol Oncol 1998;69:205-9.
    • (1998) Gynecol Oncol , vol.69 , pp. 205-209
    • Munirajan, A.K.1    Kannan, K.2    Bhuvarahamurthy, V.3
  • 26
    • 0031716133 scopus 로고    scopus 로고
    • Immunohistochemical overexpression of p16 protein associated with intact retinoblastoma protein expression in cervical cancer and cervical intraepithelial neoplasia
    • Sano T, Oyama T, Kashiwabara K, et al. Immunohistochemical overexpression of p16 protein associated with intact retinoblastoma protein expression in cervical cancer and cervical intraepithelial neoplasia. Pathol Int 1998;48:580-5.
    • (1998) Pathol Int , vol.48 , pp. 580-585
    • Sano, T.1    Oyama, T.2    Kashiwabara, K.3
  • 27
    • 0031740497 scopus 로고    scopus 로고
    • Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions
    • Sano T, Oyama T, Kashiwabara K, et al. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Am J Pathol 1998;153:1741-8.
    • (1998) Am J Pathol , vol.153 , pp. 1741-1748
    • Sano, T.1    Oyama, T.2    Kashiwabara, K.3
  • 28
    • 0034962509 scopus 로고    scopus 로고
    • Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia
    • Keating JT, Cviko A, Riethdorf S, et al. Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia. Am J Surg Pathol 2001;25:884-91.
    • (2001) Am J Surg Pathol , vol.25 , pp. 884-891
    • Keating, J.T.1    Cviko, A.2    Riethdorf, S.3
  • 29
    • 0032190669 scopus 로고    scopus 로고
    • Underexpression of cyclin-dependent kinase (CDK) inhibitors in cervical carcinoma
    • Kim YT, Cho NH, Park SW, et al. Underexpression of cyclin-dependent kinase (CDK) inhibitors in cervical carcinoma. Gynecol Oncol 1998;71:38-45.
    • (1998) Gynecol Oncol , vol.71 , pp. 38-45
    • Kim, Y.T.1    Cho, N.H.2    Park, S.W.3
  • 30
    • 0032525331 scopus 로고    scopus 로고
    • Expression of p21WAF1/CIP1 in adenocarcinoma of the uterine cervix: A possible immunohistochemical marker of a favorable prognosis
    • Lu X, Toki T, Konishi I, et al. Expression of p21WAF1/CIP1 in adenocarcinoma of the uterine cervix: a possible immunohistochemical marker of a favorable prognosis. Cancer 1998;82:2409-17.
    • (1998) Cancer , vol.82 , pp. 2409-2417
    • Lu, X.1    Toki, T.2    Konishi, I.3
  • 31
    • 0036742794 scopus 로고    scopus 로고
    • Human papillomaviruses, expression of p16, and early endocervical glandular neoplasia
    • Riethdorf L, Riethdorf S, Lee KR, et al. Human papillomaviruses, expression of p16, and early endocervical glandular neoplasia. Hum Pathol 2002;33:899-904.
    • (2002) Hum Pathol , vol.33 , pp. 899-904
    • Riethdorf, L.1    Riethdorf, S.2    Lee, K.R.3
  • 32
    • 0034927426 scopus 로고    scopus 로고
    • Expression of cyclin-dependent kinase inhibitors p16MTS1, p21WAF1, and p27KIP1 in HPV-positive and HPV-negative cervical adenocarcinomas
    • Milde-Langosch K, Riethdorf S, Kraus-Poppinghaus A, et al. Expression of cyclin-dependent kinase inhibitors p16MTS1, p21WAF1, and p27KIP1 in HPV-positive and HPV-negative cervical adenocarcinomas. Virchows Arch 2001;439:55-61.
    • (2001) Virchows Arch , vol.439 , pp. 55-61
    • Milde-Langosch, K.1    Riethdorf, S.2    Kraus-Poppinghaus, A.3
  • 33
    • 0037207502 scopus 로고    scopus 로고
    • p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and Thin-Prep smears
    • Murphy N, Ring M, Killalea AG, et al. p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and Thin-Prep smears. J Clin Pathol 2003;56:56-63.
    • (2003) J Clin Pathol , vol.56 , pp. 56-63
    • Murphy, N.1    Ring, M.2    Killalea, A.G.3
  • 34
    • 0033058696 scopus 로고    scopus 로고
    • Abnormal expression of sex steroid receptors and cell cycle-related molecules in adenocarcinoma in situ of the uterine cervix
    • Lu X, Shiozawa T, Nakayama K, et al. Abnormal expression of sex steroid receptors and cell cycle-related molecules in adenocarcinoma in situ of the uterine cervix. Int J Gynecol Pathol 1999;18:109-14.
    • (1999) Int J Gynecol Pathol , vol.18 , pp. 109-114
    • Lu, X.1    Shiozawa, T.2    Nakayama, K.3
  • 35
    • 0037289732 scopus 로고    scopus 로고
    • p16INK4a Is a useful marker for the diagnosis of adenocarcinoma of the cervix uteri and Its precursors: An immunohistochemical study with immunocytochemical correlations
    • Negri G, Egarter-Vigl E, Kasal A, et al. p16INK4a Is a useful marker for the diagnosis of adenocarcinoma of the cervix uteri and Its precursors: An immunohistochemical study with immunocytochemical correlations. Am J Surg Pathol 2003;27:187-93.
    • (2003) Am J Surg Pathol , vol.27 , pp. 187-193
    • Negri, G.1    Egarter-Vigl, E.2    Kasal, A.3
  • 36
    • 0033815503 scopus 로고    scopus 로고
    • Prevalence of human papillomavirus DNA in different histological subtypes of cervical adenocarcinoma
    • Pirog EC, Kleter B, Olgac S, et al. Prevalence of human papillomavirus DNA in different histological subtypes of cervical adenocarcinoma. Am J Pathol 2000;15:1055-62.
    • (2000) Am J Pathol , vol.15 , pp. 1055-1062
    • Pirog, E.C.1    Kleter, B.2    Olgac, S.3
  • 37
    • 0031976270 scopus 로고    scopus 로고
    • Analysis of human papillomavirus infection and molecular alterations in adenocarcinoma of the cervix
    • Ferguson AW, Svoboda-Newman SM, Frank TS. Analysis of human papillomavirus infection and molecular alterations in adenocarcinoma of the cervix. Mod Pathol 1998;11:11-8.
    • (1998) Mod Pathol , vol.11 , pp. 11-18
    • Ferguson, A.W.1    Svoboda-Newman, S.M.2    Frank, T.S.3
  • 38
    • 0032948380 scopus 로고    scopus 로고
    • Overexpression of the cyclin-dependent kinase inhibitor p16 is associated with tumor recurrence in human prostate cancer
    • Lee CT, Capodieci P, Osman I, et al. Overexpression of the cyclin-dependent kinase inhibitor p16 is associated with tumor recurrence in human prostate cancer. Clin Cancer Res 1999;5:977-83.
    • (1999) Clin Cancer Res , vol.5 , pp. 977-983
    • Lee, C.T.1    Capodieci, P.2    Osman, I.3
  • 39
    • 0036151974 scopus 로고    scopus 로고
    • Procedure for immunocytochemical detection of P16INK4A antigen in thin-layer, liquid-based specimens
    • Bibbo M, Klump WJ, DeCecco J, et al. Procedure for immunocytochemical detection of P16INK4A antigen in thin-layer, liquid-based specimens. Acta Cytol 2002;46:25-9.
    • (2002) Acta Cytol , vol.46 , pp. 25-29
    • Bibbo, M.1    Klump, W.J.2    DeCecco, J.3
  • 40
    • 0035134414 scopus 로고    scopus 로고
    • The role of human papillomavirus in cervical adenocarcinoma carcinogenesis
    • Andersson S, Rylander E, Larsson B, et al. The role of human papillomavirus in cervical adenocarcinoma carcinogenesis. Eur J Cancer 2001;37:246-50.
    • (2001) Eur J Cancer , vol.37 , pp. 246-250
    • Andersson, S.1    Rylander, E.2    Larsson, B.3
  • 41
    • 0029900446 scopus 로고    scopus 로고
    • Human papillomavirus DNA in uterine cervix squamous cell carcinoma and adenocarcinoma detected by polymerase chain reaction
    • Iwasawa A, Nieminen P, Lehtinen M, et al. Human papillomavirus DNA in uterine cervix squamous cell carcinoma and adenocarcinoma detected by polymerase chain reaction. Cancer 1996;77:2275-9.
    • (1996) Cancer , vol.77 , pp. 2275-2279
    • Iwasawa, A.1    Nieminen, P.2    Lehtinen, M.3
  • 42
    • 2642629704 scopus 로고    scopus 로고
    • International trends in the incidence of cervical cancer: I. Adenocarcinoma and adenosquamous cell carcinomas
    • Vizcaino AP, Moreno V, Bosch FX, et al. International trends in the incidence of cervical cancer: I. Adenocarcinoma and adenosquamous cell carcinomas. Int J Cancer 1998;75:536-45.
    • (1998) Int J Cancer , vol.75 , pp. 536-545
    • Vizcaino, A.P.1    Moreno, V.2    Bosch, F.X.3
  • 43
    • 0023883104 scopus 로고
    • Human papillomavirus types and localization in adenocarcinoma and adenosquamous carcinoma of the uterine cervix: A study by in situ DNA hybridization
    • Tase T, Okagaki T, Clark BA, et al. Human papillomavirus types and localization in adenocarcinoma and adenosquamous carcinoma of the uterine cervix: a study by in situ DNA hybridization. Cancer Res 1988;48:993-8.
    • (1988) Cancer Res , vol.48 , pp. 993-998
    • Tase, T.1    Okagaki, T.2    Clark, B.A.3
  • 44
    • 0032429743 scopus 로고    scopus 로고
    • Detection of human papillomavirus types in cervical adenocarcinoma by the polymerase chain reaction
    • Lee MF, Chang MC, Wu CH. Detection of human papillomavirus types in cervical adenocarcinoma by the polymerase chain reaction. Intl J Gynaecol Obstet 1998;63:265-70.
    • (1998) Intl J Gynaecol Obstet , vol.63 , pp. 265-270
    • Lee, M.F.1    Chang, M.C.2    Wu, C.H.3


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