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Volumn 22, Issue 10, 2011, Pages 2166-2178

Epidermal growth factor receptor as a biomarker for cervical cancer

Author keywords

Biomarker; Cervical cancer; Epidermal growth factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CETUXIMAB; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; ERLOTINIB; GEFITINIB; IMATINIB; LAPATINIB; MATUZUMAB; NERATINIB; TOPOTECAN; TRASTUZUMAB;

EID: 80053148870     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdq723     Document Type: Review
Times cited : (103)

References (100)
  • 1
    • 33845190140 scopus 로고    scopus 로고
    • Carcinoma of the cervix uteri FIGO 6th Annual Report on the Results of Treatment in Gynecological Cancer
    • Quinn MA, Benedet JL, Odicino F et al. Carcinoma of the cervix uteri. FIGO 6th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet 2006; 95 (Suppl 1): S43-S103.
    • (2006) Int J Gynaecol Obstet , vol.95 , Issue.SUPPL. 1
    • Quinn, M.A.1    Benedet, J.L.2    Odicino, F.3
  • 3
    • 0036362181 scopus 로고    scopus 로고
    • Why the epidermal growth factor receptor? The rationale for cancer therapy
    • Baselga J. Why the epidermal growth factor receptor? The rationale for cancer therapy. Oncologist 2002; 7 (Suppl 4): 2-8.
    • (2002) Oncologist , vol.7 , Issue.SUPPL. 4 , pp. 2-8
    • Baselga, J.1
  • 4
    • 0026692067 scopus 로고
    • Epidermal growth factor receptor expression and the presence of human papillomavirus in cervical squamous intraepithelial lesions
    • Chapman WB, Lorincz AT, Willett GD et al. Epidermal growth factor receptor expression and the presence of human papillomavirus in cervical squamous intraepithelial lesions. Int J Gynecol Pathol 1992; 11: 221-226.
    • (1992) Int J Gynecol Pathol , vol.11 , pp. 221-226
    • Chapman, W.B.1    Lorincz, A.T.2    Willett, G.D.3
  • 5
    • 0036221471 scopus 로고    scopus 로고
    • The causal relation between human papillomavirus and cervical cancer
    • Bosch FX, Lorincz A, Munoz N et al. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol 2002; 55: 244-265.
    • (2002) J Clin Pathol , vol.55 , pp. 244-265
    • Bosch, F.X.1    Lorincz, A.2    Munoz, N.3
  • 6
    • 17844396023 scopus 로고    scopus 로고
    • HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes
    • Zhang B, Srirangam A, Potter DA, Roman A. HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes. Oncogene 2005; 24: 2585-2588.
    • (2005) Oncogene , vol.24 , pp. 2585-2588
    • Zhang, B.1    Srirangam, A.2    Potter, D.A.3    Roman, A.4
  • 7
    • 0027216860 scopus 로고
    • The E5 oncoprotein of human papillomavirus type 16 transforms fibroblasts and effects the downregulation of the epidermal growth factor receptor in keratinocytes
    • Straight SW, Hinkle PM, Jewers RJ, McCance DJ. The E5 oncoprotein of human papillomavirus type 16 transforms fibroblasts and effects the downregulation of the epidermal growth factor receptor in keratinocytes. J Virol 1993; 67: 4521-4532.
    • (1993) J Virol , vol.67 , pp. 4521-4532
    • Straight, S.W.1    Hinkle, P.M.2    Jewers, R.J.3    McCance, D.J.4
  • 8
    • 0042572079 scopus 로고    scopus 로고
    • The biochemical and biological functions of human papillomavirus type 16 E5 protein
    • Tsai TC, Chen SL. The biochemical and biological functions of human papillomavirus type 16 E5 protein. Arch Virol 2003; 148: 1445-1453.
    • (2003) Arch Virol , vol.148 , pp. 1445-1453
    • Tsai, T.C.1    Chen, S.L.2
  • 9
    • 0035328577 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes
    • Akerman GS, Tolleson WH, Brown KL et al. Human papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes. Cancer Res 2001; 61: 3837-3843.
    • (2001) Cancer Res , vol.61 , pp. 3837-3843
    • Akerman, G.S.1    Tolleson, W.H.2    Brown, K.L.3
  • 10
    • 0032505713 scopus 로고    scopus 로고
    • Transcriptional regulation of the EGF receptor promoter by HPV16 and retinoic acid in human ectocervical epithelial cells
    • Sizemore N, Choo CK, Eckert RL, Rorke EA. Transcriptional regulation of the EGF receptor promoter by HPV16 and retinoic acid in human ectocervical epithelial cells. Exp Cell Res 1998; 244: 349-356.
    • (1998) Exp Cell Res , vol.244 , pp. 349-356
    • Sizemore, N.1    Choo, C.K.2    Eckert, R.L.3    Rorke, E.A.4
  • 11
    • 0030817148 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor and human papillomavirus E6/E7 proteins in cervical carcinoma cells
    • Hu G, Liu W, Mendelsohn J et al. Expression of epidermal growth factor receptor and human papillomavirus E6/E7 proteins in cervical carcinoma cells. J Natl Cancer Inst 1997; 89: 1271-1276.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1271-1276
    • Hu, G.1    Liu, W.2    Mendelsohn, J.3
  • 12
    • 1242319406 scopus 로고    scopus 로고
    • Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins
    • Duensing S, Munger K. Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. Int J Cancer 2004; 109: 157-162.
    • (2004) Int J Cancer , vol.109 , pp. 157-162
    • Duensing, S.1    Munger, K.2
  • 13
    • 47649119001 scopus 로고    scopus 로고
    • Absence of epidermal growth factor receptor mutations in cervical cancer
    • Arias-Pulido H, Joste N, Chavez A et al. Absence of epidermal growth factor receptor mutations in cervical cancer. Int J Gynecol Cancer 2008; 18: 749-754.
    • (2008) Int J Gynecol Cancer , vol.18 , pp. 749-754
    • Arias-Pulido, H.1    Joste, N.2    Chavez, A.3
  • 14
    • 67651093726 scopus 로고    scopus 로고
    • Molecular characterization of 565 EGFR PDGFRA and VEGFR2 in cervical adenosquamous carcinoma
    • Longatto-Filho A, Pinheiro C, Martinho O et al. Molecular characterization of 565 EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma. BMC Cancer 2009; 9: 212.
    • (2009) BMC Cancer , vol.9 , pp. 212
    • Longatto-Filho, A.1    Pinheiro, C.2    Martinho, O.3
  • 16
    • 55449112096 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted therapy
    • Spec No
    • West CM, Joseph L, Bhana S. Epidermal growth factor receptor-targeted therapy. Br J Radiol 2008; 81 Spec No 1: S36-S44.
    • (2008) Br J Radiol , vol.81 , Issue.1
    • West, C.M.1    Joseph, L.2    Bhana, S.3
  • 17
    • 44249111440 scopus 로고    scopus 로고
    • EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer
    • Sobrero AF, Maurel J, Fehrenbacher L et al. EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. J Clin Oncol 2008; 26: 2311-2319.
    • (2008) J Clin Oncol , vol.26 , pp. 2311-2319
    • Sobrero, A.F.1    Maurel, J.2    Fehrenbacher, L.3
  • 18
    • 70350582832 scopus 로고    scopus 로고
    • Cetuximab in metastatic or recurrent head and neck cancer: the EXTREME trial
    • Rivera F, Garcia-Castano A, Vega N et al. Cetuximab in metastatic or recurrent head and neck cancer: the EXTREME trial. Expert Rev Anticancer Ther 2009; 9: 1421-1428.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 1421-1428
    • Rivera, F.1    Garcia-Castano, A.2    Vega, N.3
  • 19
    • 38049041406 scopus 로고    scopus 로고
    • Erlotinib/gemcitabine for first-line treatment of locally advanced or metastatic adenocarcinoma of the pancreas
    • discussion 1706-1699, 1712 1715
    • Senderowicz AM, Johnson JR, Sridhara R et al. Erlotinib/gemcitabine for first-line treatment of locally advanced or metastatic adenocarcinoma of the pancreas. Oncology (Williston Park) 2007; 21: 1696-1706; discussion 1706-1699, 1712, 1715.
    • (2007) Oncology (Williston Park) , vol.21 , pp. 1696-1706
    • Senderowicz, A.M.1    Johnson, J.R.2    Sridhara, R.3
  • 20
    • 25144488564 scopus 로고    scopus 로고
    • Approval summary for erlotinib for treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of at least one prior chemotherapy regimen
    • Johnson JR, Cohen M, Sridhara R et al. Approval summary for erlotinib for treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of at least one prior chemotherapy regimen. Clin Cancer Res 2005; 11: 6414-6421.
    • (2005) Clin Cancer Res , vol.11 , pp. 6414-6421
    • Johnson, J.R.1    Cohen, M.2    Sridhara, R.3
  • 21
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004; 351: 337-345.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 22
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamouscell carcinoma of the head and neck
    • Bonner JA, Harari PM, Giralt J et al. Radiotherapy plus cetuximab for squamouscell carcinoma of the head and neck. N Engl J Med 2006; 354: 567-578.
    • (2006) N Engl J Med , vol.354 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3
  • 23
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • Van Cutsem E, Kohne CH, Hitre E et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009; 360: 1408-1417.
    • (2009) N Engl J Med , vol.360 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 24
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis CS, Khambata-Ford S, Jonker DJ et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008; 359: 1757-1765.
    • (2008) N Engl J Med , vol.359 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 25
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • Amado RG, Wolf M, Peeters M et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008; 26: 1626-1634.
    • (2008) J Clin Oncol , vol.26 , pp. 1626-1634
    • Amado, R.G.1    Wolf, M.2    Peeters, M.3
  • 26
    • 72449204284 scopus 로고    scopus 로고
    • High epiregulin (EREG) gene expression plus K-ras wild-type (WT) status as predictors of cetuximab benefit in the treatment of advanced colorectal cancer (ACRC): results from NCIC CTG CO 17: a phase III trial of cetuximab versus best supportive care (BSC)
    • Jonker DJ, Karapetis C, Harbison C et al. High epiregulin (EREG) gene expression plus K-ras wild-type (WT) status as predictors of cetuximab benefit in the treatment of advanced colorectal cancer (ACRC): results from NCIC CTG CO.17: a phase III trial of cetuximab versus best supportive care (BSC). J Clin Oncol 2009; 27: (Abstr 4016).
    • (2009) J Clin Oncol , vol.27
    • Jonker, D.J.1    Karapetis, C.2    Harbison, C.3
  • 27
    • 24944497744 scopus 로고    scopus 로고
    • Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
    • Eberhard DA, Johnson BE, Amler LC et al. Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 2005; 23: 5900-5909.
    • (2005) J Clin Oncol , vol.23 , pp. 5900-5909
    • Eberhard, D.A.1    Johnson, B.E.2    Amler, L.C.3
  • 28
    • 51349091459 scopus 로고    scopus 로고
    • Correlating EGFR expression with receptor-binding properties and internalization of 64Cu-DOTA-cetuximab in 5 cervical cancer cell lines
    • Eiblmaier M, Meyer LA, Watson MA et al. Correlating EGFR expression with receptor-binding properties and internalization of 64Cu-DOTA-cetuximab in 5 cervical cancer cell lines. J Nucl Med 2008; 49: 1472-1479.
    • (2008) J Nucl Med , vol.49 , pp. 1472-1479
    • Eiblmaier, M.1    Meyer, L.A.2    Watson, M.A.3
  • 29
    • 34548124985 scopus 로고    scopus 로고
    • Overexpression of epidermal growth factor type-1 receptor (EGF-R1) in cervical cancer: implications for Cetuximab-mediated therapy in recurrent/metastatic disease
    • Bellone S, Frera G, Landolfi G et al. Overexpression of epidermal growth factor type-1 receptor (EGF-R1) in cervical cancer: implications for Cetuximab-mediated therapy in recurrent/metastatic disease. Gynecol Oncol 2007; 106: 513-520.
    • (2007) Gynecol Oncol , vol.106 , pp. 513-520
    • Bellone, S.1    Frera, G.2    Landolfi, G.3
  • 30
    • 0027096785 scopus 로고
    • Polymorphonuclear leukocytes-mediated lysis of A431 cells induced by IgG1 mouse anti-epidermal growth factor receptor monoclonal antibodies
    • Kawamoto T, Kishimoto K, Takahashi K et al. Polymorphonuclear leukocytes-mediated lysis of A431 cells induced by IgG1 mouse anti-epidermal growth factor receptor monoclonal antibodies. In Vitro Cell Dev Biol 1992; 28A: 782-786.
    • (1992) In Vitro Cell Dev Biol , vol.28 A , pp. 782-786
    • Kawamoto, T.1    Kishimoto, K.2    Takahashi, K.3
  • 31
    • 0035116907 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha sensitizes low epidermal growth factor receptor (EGFR)-expressing carcinomas for anti-EGFR therapy
    • Hambek M, Solbach C, Schnuerch HG et al. Tumor necrosis factor alpha sensitizes low epidermal growth factor receptor (EGFR)-expressing carcinomas for anti-EGFR therapy. Cancer Res 2001; 61: 1045-1049.
    • (2001) Cancer Res , vol.61 , pp. 1045-1049
    • Hambek, M.1    Solbach, C.2    Schnuerch, H.G.3
  • 32
    • 70249143558 scopus 로고    scopus 로고
    • Combination of cetuximab with chemoradiation, trastuzumab or MAPK inhibitors: mechanisms of sensitisation of cervical cancer cells
    • Meira DD, de Almeida VH, Mororo JS et al. Combination of cetuximab with chemoradiation, trastuzumab or MAPK inhibitors: mechanisms of sensitisation of cervical cancer cells. Br J Cancer 2009; 101: 782-791.
    • (2009) Br J Cancer , vol.101 , pp. 782-791
    • Meira, D.D.1    de Almeida, V.H.2    Mororo, J.S.3
  • 33
    • 34547189602 scopus 로고    scopus 로고
    • Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells
    • Chen Y, Low TY, Choong LY et al. Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells. Proteomics 2007; 7: 2384-2397.
    • (2007) Proteomics , vol.7 , pp. 2384-2397
    • Chen, Y.1    Low, T.Y.2    Choong, L.Y.3
  • 34
    • 0029025332 scopus 로고
    • Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas
    • Wikstrand CJ, Hale LP, Batra SK et al. Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. Cancer Res 1995; 55: 3140-3148.
    • (1995) Cancer Res , vol.55 , pp. 3140-3148
    • Wikstrand, C.J.1    Hale, L.P.2    Batra, S.K.3
  • 35
    • 33646716077 scopus 로고    scopus 로고
    • Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors
    • Ji H, Zhao X, Yuza Y et al. Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. Proc Natl Acad Sci U S A 2006; 103: 7817-7822.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7817-7822
    • Ji, H.1    Zhao, X.2    Yuza, Y.3
  • 36
    • 34147184365 scopus 로고    scopus 로고
    • Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel
    • Sarkaria JN, Yang L, Grogan PT et al. Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel. Mol Cancer Ther 2007; 6: 1167-1174.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1167-1174
    • Sarkaria, J.N.1    Yang, L.2    Grogan, P.T.3
  • 37
    • 33845926387 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain
    • Lee JC, Vivanco I, Beroukhim R et al. Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain. PLoS Med 2006; 3: e485.
    • (2006) PLoS Med , vol.3
    • Lee, J.C.1    Vivanco, I.2    Beroukhim, R.3
  • 38
    • 34248386122 scopus 로고    scopus 로고
    • Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma
    • Kang S, Kim HS, Seo SS et al. Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma. Gynecol Oncol 2007; 105: 662-666.
    • (2007) Gynecol Oncol , vol.105 , pp. 662-666
    • Kang, S.1    Kim, H.S.2    Seo, S.S.3
  • 39
    • 0242269027 scopus 로고    scopus 로고
    • P63 and EGFR as prognostic predictors in stage IIB radiation-treated cervical squamous cell carcinoma
    • Cho NH, Kim YB, Park TK et al. P63 and EGFR as prognostic predictors in stage IIB radiation-treated cervical squamous cell carcinoma. Gynecol Oncol 2003; 91: 346-353.
    • (2003) Gynecol Oncol , vol.91 , pp. 346-353
    • Cho, N.H.1    Kim, Y.B.2    Park, T.K.3
  • 40
    • 0038386695 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) negatively affect overall survival in carcinoma of the cervix treated with radiotherapy
    • Gaffney DK, Haslam D, Tsodikov A et al. Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) negatively affect overall survival in carcinoma of the cervix treated with radiotherapy. Int J Radiat Oncol Biol Phys 2003; 56: 922-928.
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 922-928
    • Gaffney, D.K.1    Haslam, D.2    Tsodikov, A.3
  • 41
    • 0027518792 scopus 로고
    • Prognostic value of epidermal growth factor receptor expression in cervical carcinoma
    • Hale RJ, Buckley CH, Gullick WJ et al. Prognostic value of epidermal growth factor receptor expression in cervical carcinoma. J Clin Pathol 1993; 46: 149-153.
    • (1993) J Clin Pathol , vol.46 , pp. 149-153
    • Hale, R.J.1    Buckley, C.H.2    Gullick, W.J.3
  • 42
    • 0022160411 scopus 로고
    • Antibodies to the autophosphorylation sites of the epidermal growth factor receptor protein-tyrosine kinase as probes of structure and function
    • Gullick WJ, Downward J, Waterfield MD. Antibodies to the autophosphorylation sites of the epidermal growth factor receptor protein-tyrosine kinase as probes of structure and function. EMBO J 1985; 4: 2869-2877.
    • (1985) EMBO J , vol.4 , pp. 2869-2877
    • Gullick, W.J.1    Downward, J.2    Waterfield, M.D.3
  • 43
    • 0036148613 scopus 로고    scopus 로고
    • Immunohistochemical assay of p53, cyclin D1, c-erbB2 EGFr and Ki-67 proteins in HPV-positive and HPV-negative cervical cancers
    • Kedzia W, Schmidt M, Frankowski A, Spaczynski M. Immunohistochemical assay of p53, cyclin D1, c-erbB2, EGFr and Ki-67 proteins in HPV-positive and HPV-negative cervical cancers. Folia Histochem Cytobiol 2002; 40: 37-41.
    • (2002) Folia Histochem Cytobiol , vol.40 , pp. 37-41
    • Kedzia, W.1    Schmidt, M.2    Frankowski, A.3    Spaczynski, M.4
  • 44
    • 0033042754 scopus 로고    scopus 로고
    • Oncogene alterations in carcinomas of the uterine cervix: overexpression of the epidermal growth factor receptor is associated with poor prognosis
    • Kersemaekers AM, Fleuren GJ, Kenter GG et al. Oncogene alterations in carcinomas of the uterine cervix: overexpression of the epidermal growth factor receptor is associated with poor prognosis. Clin Cancer Res 1999; 5: 577-586.
    • (1999) Clin Cancer Res , vol.5 , pp. 577-586
    • Kersemaekers, A.M.1    Fleuren, G.J.2    Kenter, G.G.3
  • 45
    • 0019469709 scopus 로고
    • Epidermal growth factor receptors
    • Adamson ED, Rees AR. Epidermal growth factor receptors. Mol Cell Biochem 1981; 34: 129-152.
    • (1981) Mol Cell Biochem , vol.34 , pp. 129-152
    • Adamson, E.D.1    Rees, A.R.2
  • 46
    • 12144290754 scopus 로고    scopus 로고
    • Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: a potential predictor of poor survival
    • Kim GE, Kim YB, Cho NH et al. Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: a potential predictor of poor survival. Clin Cancer Res 2004; 10: 1366-1374.
    • (2004) Clin Cancer Res , vol.10 , pp. 1366-1374
    • Kim, G.E.1    Kim, Y.B.2    Cho, N.H.3
  • 47
    • 0029954643 scopus 로고    scopus 로고
    • Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor, and c-erbB-2 in early cervical squamous cell carcinoma An immunohistochemical study
    • Kristensen GB, Holm R, Abeler VM, Trope CG. Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor, and c-erbB-2 in early cervical squamous cell carcinoma. An immunohistochemical study. Cancer 1996; 78: 433-440.
    • (1996) Cancer , vol.78 , pp. 433-440
    • Kristensen, G.B.1    Holm, R.2    Abeler, V.M.3    Trope, C.G.4
  • 48
    • 73149105764 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor (EGFR) and activated EGFR predict poor response to (chemo)radiation and survival in cervical cancer
    • Noordhuis MG, Eijsink JJ, Ten Hoor KA et al. Expression of epidermal growth factor receptor (EGFR) and activated EGFR predict poor response to (chemo)radiation and survival in cervical cancer. Clin Cancer Res 2009; 15: 7389-7397.
    • (2009) Clin Cancer Res , vol.15 , pp. 7389-7397
    • Noordhuis, M.G.1    Eijsink, J.J.2    Ten Hoor, K.A.3
  • 49
    • 58649111239 scopus 로고    scopus 로고
    • Negative prognostic impact of the coexpression of epidermal growth factor receptor and c-erbB-2 in locally advanced cervical cancer
    • Perez-Regadera J, Sanchez-Munoz A, De-la-Cruz J et al. Negative prognostic impact of the coexpression of epidermal growth factor receptor and c-erbB-2 in locally advanced cervical cancer. Oncology 2009; 76: 133-141.
    • (2009) Oncology , vol.76 , pp. 133-141
    • Perez-Regadera, J.1    Sanchez-Munoz, A.2    De-la-Cruz, J.3
  • 50
    • 0042456000 scopus 로고    scopus 로고
    • Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervix
    • Pillai MR, Jayaprakash PG, Nair MK. Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervix. J Cancer Res Clin Oncol 1998; 124: 456-461.
    • (1998) J Cancer Res Clin Oncol , vol.124 , pp. 456-461
    • Pillai, M.R.1    Jayaprakash, P.G.2    Nair, M.K.3
  • 51
    • 34250870226 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and epidermal growth factor receptor expressions in different histological subtypes of cervical carcinomas
    • Baltazar F, Filho AL, Pinheiro C et al. Cyclooxygenase-2 and epidermal growth factor receptor expressions in different histological subtypes of cervical carcinomas. Int J Gynecol Pathol 2007; 26: 235-241.
    • (2007) Int J Gynecol Pathol , vol.26 , pp. 235-241
    • Baltazar, F.1    Filho, A.L.2    Pinheiro, C.3
  • 52
    • 0020068317 scopus 로고
    • A native 170 000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles
    • Cohen S, Ushiro H, Stoscheck C, Chinkers M. A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles. J Biol Chem 1982; 257: 1523-1531.
    • (1982) J Biol Chem , vol.257 , pp. 1523-1531
    • Cohen, S.1    Ushiro, H.2    Stoscheck, C.3    Chinkers, M.4
  • 53
    • 34447636969 scopus 로고    scopus 로고
    • Is EGFR a moving target during radiotherapy of carcinoma of the uterine cervix?
    • Cerciello F, Riesterer O, Sherweif M et al. Is EGFR a moving target during radiotherapy of carcinoma of the uterine cervix? Gynecol Oncol 2007; 106: 394-399.
    • (2007) Gynecol Oncol , vol.106 , pp. 394-399
    • Cerciello, F.1    Riesterer, O.2    Sherweif, M.3
  • 54
    • 0032894071 scopus 로고    scopus 로고
    • The expression of type I growth factor receptors in the squamous neoplastic changes of uterine cervix
    • Chang JL, Tsao YP, Liu DW et al. The expression of type I growth factor receptors in the squamous neoplastic changes of uterine cervix. Gynecol Oncol 1999; 73: 62-71.
    • (1999) Gynecol Oncol , vol.73 , pp. 62-71
    • Chang, J.L.1    Tsao, Y.P.2    Liu, D.W.3
  • 55
    • 0025977870 scopus 로고
    • Expression of ras oncogene product and EGF receptor in cervical squamous cell carcinomas and its relationship to lymph node involvement
    • Hayashi Y, Hachisuga T, Iwasaka T et al. Expression of ras oncogene product and EGF receptor in cervical squamous cell carcinomas and its relationship to lymph node involvement. Gynecol Oncol 1991; 40: 147-151.
    • (1991) Gynecol Oncol , vol.40 , pp. 147-151
    • Hayashi, Y.1    Hachisuga, T.2    Iwasaka, T.3
  • 56
    • 0033050181 scopus 로고    scopus 로고
    • Oncogene expression and microvessel count in recurrent and nonrecurrent stage Ib squamous cell carcinoma of the cervix
    • Hove MG, Dinh TV, Hannigan EV et al. Oncogene expression and microvessel count in recurrent and nonrecurrent stage Ib squamous cell carcinoma of the cervix. J Reprod Med 1999; 44: 493-496.
    • (1999) J Reprod Med , vol.44 , pp. 493-496
    • Hove, M.G.1    Dinh, T.V.2    Hannigan, E.V.3
  • 57
    • 69249167999 scopus 로고    scopus 로고
    • Discrepancies in expression and prognostic value of tumor markers in adenocarcinoma and squamous cell carcinoma in cervical cancer
    • Lindstrom AK, Tot T, Stendahl U et al. Discrepancies in expression and prognostic value of tumor markers in adenocarcinoma and squamous cell carcinoma in cervical cancer. Anticancer Res 2009; 29: 2577-2578.
    • (2009) Anticancer Res , vol.29 , pp. 2577-2578
    • Lindstrom, A.K.1    Tot, T.2    Stendahl, U.3
  • 58
    • 0026557152 scopus 로고
    • Immunohistochemical demonstration of elevated expression of epidermal growth factor receptor in the neoplastic changes of cervical squamous epithelium
    • Maruo T, Yamasaki M, Ladines-Llave CA, Mochizuki M. Immunohistochemical demonstration of elevated expression of epidermal growth factor receptor in the neoplastic changes of cervical squamous epithelium. Cancer 1992; 69: 1182-1187.
    • (1992) Cancer , vol.69 , pp. 1182-1187
    • Maruo, T.1    Yamasaki, M.2    Ladines-Llave, C.A.3    Mochizuki, M.4
  • 59
    • 0035349958 scopus 로고    scopus 로고
    • Abnormal expression of pan-ras, c-myc and tp53 in squamous cell carcinoma of cervix: correlation with HPV and prognosis
    • Ngan HY, Cheung AN, Liu SS et al. Abnormal expression of pan-ras, c-myc and tp53 in squamous cell carcinoma of cervix: correlation with HPV and prognosis. Oncol Rep 2001; 8: 557-561.
    • (2001) Oncol Rep , vol.8 , pp. 557-561
    • Ngan, H.Y.1    Cheung, A.N.2    Liu, S.S.3
  • 60
    • 0023257732 scopus 로고
    • Epidermal growth factor receptors in lung tumours
    • Berger MS, Gullick WJ, Greenfield C et al. Epidermal growth factor receptors in lung tumours. J Pathol 1987; 152: 297-307.
    • (1987) J Pathol , vol.152 , pp. 297-307
    • Berger, M.S.1    Gullick, W.J.2    Greenfield, C.3
  • 61
    • 50549101389 scopus 로고    scopus 로고
    • EGFR and HER2 expression in primary cervical cancers and corresponding lymph node metastases: implications for targeted radiotherapy
    • Shen L, Shui Y, Wang X et al. EGFR and HER2 expression in primary cervical cancers and corresponding lymph node metastases: implications for targeted radiotherapy. BMC Cancer 2008; 8: 232.
    • (2008) BMC Cancer , vol.8 , pp. 232
    • Shen, L.1    Shui, Y.2    Wang, X.3
  • 62
    • 0032932656 scopus 로고    scopus 로고
    • Aberrant expression of the cell cycle associated proteins TP53, MDM2, p21, p27, cdk4, cyclin D1, RB, and EGFR in cervical carcinomas
    • Skomedal H, Kristensen GB, Lie AK, Holm R. Aberrant expression of the cell cycle associated proteins TP53, MDM2, p21, p27, cdk4, cyclin D1, RB, and EGFR in cervical carcinomas. Gynecol Oncol 1999; 73: 223-228.
    • (1999) Gynecol Oncol , vol.73 , pp. 223-228
    • Skomedal, H.1    Kristensen, G.B.2    Lie, A.K.3    Holm, R.4
  • 63
    • 67649556464 scopus 로고    scopus 로고
    • Correlation among six biologic factors (p53, p21(WAF1), MIB-1, EGFR, HER2, and Bcl-2) and clinical outcomes after curative chemoradiation therapy in squamous cell cervical cancer
    • Yamashita H, Murakami N, Asari T et al. Correlation among six biologic factors (p53, p21(WAF1), MIB-1, EGFR, HER2, and Bcl-2) and clinical outcomes after curative chemoradiation therapy in squamous cell cervical cancer. Int J Radiat Oncol Biol Phys 2009; 74: 1165-1172.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 1165-1172
    • Yamashita, H.1    Murakami, N.2    Asari, T.3
  • 64
    • 34247127937 scopus 로고    scopus 로고
    • The prognostic significance of human epidermal growth factor receptor correlations in squamous cell cervical carcinoma
    • Fuchs I, Vorsteher N, Buhler H et al. The prognostic significance of human epidermal growth factor receptor correlations in squamous cell cervical carcinoma. Anticancer Res 2007; 27: 959-963.
    • (2007) Anticancer Res , vol.27 , pp. 959-963
    • Fuchs, I.1    Vorsteher, N.2    Buhler, H.3
  • 65
    • 0035077048 scopus 로고    scopus 로고
    • Abnormal expression of epidermal growth factor receptor and c-erbB2 in squamous cell carcinoma of the cervix: correlation with human papillomavirus and prognosis
    • Ngan HY, Cheung AN, Liu SS et al. Abnormal expression of epidermal growth factor receptor and c-erbB2 in squamous cell carcinoma of the cervix: correlation with human papillomavirus and prognosis. Tumour Biol 2001; 22: 176-183.
    • (2001) Tumour Biol , vol.22 , pp. 176-183
    • Ngan, H.Y.1    Cheung, A.N.2    Liu, S.S.3
  • 66
    • 0023019294 scopus 로고
    • Estrogen receptor analysis on biopsies and fine-needle aspirates from human breast carcinoma Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies
    • Reiner A, Spona J, Reiner G et al. Estrogen receptor analysis on biopsies and fine-needle aspirates from human breast carcinoma. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies. Am J Pathol 1986; 125: 443-449.
    • (1986) Am J Pathol , vol.125 , pp. 443-449
    • Reiner, A.1    Spona, J.2    Reiner, G.3
  • 67
    • 0027377043 scopus 로고
    • Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer Computer-assisted image analysis (QIC score) vs. subjective grading (IRS)
    • Remmele W, Schicketanz KH. Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer. Computer-assisted image analysis (QIC score) vs. subjective grading (IRS). Pathol Res Pract 1993; 189: 862-866.
    • (1993) Pathol Res Pract , vol.189 , pp. 862-866
    • Remmele, W.1    Schicketanz, K.H.2
  • 68
    • 0036171201 scopus 로고    scopus 로고
    • Radioimmunohistochemistry of epidermal growth factor receptor in breast cancer
    • Robertson KW, Reeves JR, Lannigan AK et al. Radioimmunohistochemistry of epidermal growth factor receptor in breast cancer. Arch Pathol Lab Med 2002; 126: 177-181.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 177-181
    • Robertson, K.W.1    Reeves, J.R.2    Lannigan, A.K.3
  • 69
    • 0036912509 scopus 로고    scopus 로고
    • Quality assurance for detection of estrogen and progesterone receptors by immunohistochemistry in Austrian pathology laboratories
    • Regitnig P, Reiner A, Dinges HP et al. Quality assurance for detection of estrogen and progesterone receptors by immunohistochemistry in Austrian pathology laboratories. Virchows Arch 2002; 441: 328-334.
    • (2002) Virchows Arch , vol.441 , pp. 328-334
    • Regitnig, P.1    Reiner, A.2    Dinges, H.P.3
  • 71
    • 31144475745 scopus 로고    scopus 로고
    • Assessment of epidermal growth factor receptor (EGFR) signaling in paired colorectal cancer and normal colon tissue samples using computer-aided immunohistochemical analysis
    • Messersmith W, Oppenheimer D, Peralba J et al. Assessment of epidermal growth factor receptor (EGFR) signaling in paired colorectal cancer and normal colon tissue samples using computer-aided immunohistochemical analysis. Cancer Biol Ther 2005; 4: 1381-1386.
    • (2005) Cancer Biol Ther , vol.4 , pp. 1381-1386
    • Messersmith, W.1    Oppenheimer, D.2    Peralba, J.3
  • 72
    • 28844448710 scopus 로고    scopus 로고
    • Optical imaging of cervical pre-cancers with structured illumination: an integrated approach
    • Rahman M, Abd-El-Barr M, Mack V et al. Optical imaging of cervical pre-cancers with structured illumination: an integrated approach. Gynecol Oncol 2005; 99: S112-S115.
    • (2005) Gynecol Oncol , vol.99
    • Rahman, M.1    Abd-El-Barr, M.2    Mack, V.3
  • 73
    • 28844434999 scopus 로고    scopus 로고
    • Fluorescent nanocrystals for use in early cervical cancer detection
    • Nida DL, Rahman MS, Carlson KD et al. Fluorescent nanocrystals for use in early cervical cancer detection. Gynecol Oncol 2005; 99: S89-S94.
    • (2005) Gynecol Oncol , vol.99
    • Nida, D.L.1    Rahman, M.S.2    Carlson, K.D.3
  • 74
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 2000; 69: 145-182.
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 75
    • 2942514601 scopus 로고    scopus 로고
    • Analysis of chromosomes 3, 7, X and the EGFR gene in uterine cervical cancer progression
    • Marzano R, Corrado G, Merola R et al. Analysis of chromosomes 3, 7, X and the EGFR gene in uterine cervical cancer progression. Euro J Cancer 2004; 40: 1624-1629.
    • (2004) Euro J Cancer , vol.40 , pp. 1624-1629
    • Marzano, R.1    Corrado, G.2    Merola, R.3
  • 76
    • 0009483341 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor in carcinoma of the cervix
    • Kim JW, Kim YT, Kim DK et al. Expression of epidermal growth factor receptor in carcinoma of the cervix. Gynecol Oncol 1996; 60: 283-287.
    • (1996) Gynecol Oncol , vol.60 , pp. 283-287
    • Kim, J.W.1    Kim, Y.T.2    Kim, D.K.3
  • 77
    • 15444339645 scopus 로고    scopus 로고
    • Correlation between EGFR and c-erbB-2 oncoprotein status and response to neoadjuvant chemotherapy in cervical carcinoma
    • Kim JW, Kim YT, Kim DK. Correlation between EGFR and c-erbB-2 oncoprotein status and response to neoadjuvant chemotherapy in cervical carcinoma. Yonsei Med J 1999; 40: 207-214.
    • (1999) Yonsei Med J , vol.40 , pp. 207-214
    • Kim, J.W.1    Kim, Y.T.2    Kim, D.K.3
  • 78
    • 0036920080 scopus 로고    scopus 로고
    • Correlation between expression of EGFR and the prognosis of patients with cervical carcinoma
    • Kim YT, Park SW, Kim JW. Correlation between expression of EGFR and the prognosis of patients with cervical carcinoma. Gynecol Oncol 2002; 87: 84-89.
    • (2002) Gynecol Oncol , vol.87 , pp. 84-89
    • Kim, Y.T.1    Park, S.W.2    Kim, J.W.3
  • 79
    • 0034485637 scopus 로고    scopus 로고
    • Detection of epidermal growth factor receptor in the serum of patients with cervical carcinoma
    • Oh MJ, Choi JH, Kim IH et al. Detection of epidermal growth factor receptor in the serum of patients with cervical carcinoma. Clin Cancer Res 2000; 6: 4760-4763.
    • (2000) Clin Cancer Res , vol.6 , pp. 4760-4763
    • Oh, M.J.1    Choi, J.H.2    Kim, I.H.3
  • 80
    • 0024787440 scopus 로고
    • The expression of EGF receptors EGF-like factors and c-myc in ovarian and cervical carcinomas and their potential clinical significance
    • Kohler M, Janz I, Wintzer HO et al. The expression of EGF receptors, EGF-like factors and c-myc in ovarian and cervical carcinomas and their potential clinical significance. Anticancer Res 1989; 9: 1537-1547.
    • (1989) Anticancer Res , vol.9 , pp. 1537-1547
    • Kohler, M.1    Janz, I.2    Wintzer, H.O.3
  • 81
    • 0032548881 scopus 로고    scopus 로고
    • Epidermal-growth-factor receptor correlates negatively with cell density in cervical squamous epithelium and is down-regulated in cancers of the human uterus
    • Pfeiffer D, Kimmig R, Herrmann J et al. Epidermal-growth-factor receptor correlates negatively with cell density in cervical squamous epithelium and is down-regulated in cancers of the human uterus. Int J Cancer 1998; 79: 49-55.
    • (1998) Int J Cancer , vol.79 , pp. 49-55
    • Pfeiffer, D.1    Kimmig, R.2    Herrmann, J.3
  • 82
    • 0024599422 scopus 로고
    • Clinical implications of the epidermal growth factor receptor in the squamous cell carcinoma of the uterine cervix
    • Pfeiffer D, Stellwag B, Pfeiffer A et al. Clinical implications of the epidermal growth factor receptor in the squamous cell carcinoma of the uterine cervix. Gynecol Oncol 1989; 33: 146-150.
    • (1989) Gynecol Oncol , vol.33 , pp. 146-150
    • Pfeiffer, D.1    Stellwag, B.2    Pfeiffer, A.3
  • 83
    • 0032579543 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) is not related to the prognosis of cervical cancer
    • Scambia G, Ferrandina G, Distefano M et al. Epidermal growth factor receptor (EGFR) is not related to the prognosis of cervical cancer. Cancer Lett 1998; 123: 135-139.
    • (1998) Cancer Lett , vol.123 , pp. 135-139
    • Scambia, G.1    Ferrandina, G.2    Distefano, M.3
  • 84
    • 0030851154 scopus 로고    scopus 로고
    • Quantitative determination of the epidermal growth factor receptor in cervical cancer and normal cervical epithelium by 2-color flow cytometry: evidence for down-regulation in cervical cancer
    • Kimmig R, Pfeiffer D, Landsmann H, Hepp H. Quantitative determination of the epidermal growth factor receptor in cervical cancer and normal cervical epithelium by 2-color flow cytometry: evidence for down-regulation in cervical cancer. Int J Cancer 1997; 74: 365-373.
    • (1997) Int J Cancer , vol.74 , pp. 365-373
    • Kimmig, R.1    Pfeiffer, D.2    Landsmann, H.3    Hepp, H.4
  • 85
    • 0025951005 scopus 로고
    • Multiparameter flow-cytometric quantitation of epidermal growth factor receptor and c-erbB-2 oncoprotein in normal and neoplastic tissues of the female genital tract
    • van Dam PA, Lowe DG, Watson JV et al. Multiparameter flow-cytometric quantitation of epidermal growth factor receptor and c-erbB-2 oncoprotein in normal and neoplastic tissues of the female genital tract. Gynecol Oncol 1991; 42: 256-264.
    • (1991) Gynecol Oncol , vol.42 , pp. 256-264
    • van Dam, P.A.1    Lowe, D.G.2    Watson, J.V.3
  • 86
    • 0028902755 scopus 로고
    • Multiparameter flow cytometric measurement of epidermal growth factor receptor and c-erbB-2 oncoprotein in cultured cells and in fresh and preserved solid tumor cells
    • van Dam PA, Lowe DG, Watson JV, Shepherd JH. Multiparameter flow cytometric measurement of epidermal growth factor receptor and c-erbB-2 oncoprotein in cultured cells and in fresh and preserved solid tumor cells. Int J Gynecol Cancer 1995; 5: 20-28.
    • (1995) Int J Gynecol Cancer , vol.5 , pp. 20-28
    • van Dam, P.A.1    Lowe, D.G.2    Watson, J.V.3    Shepherd, J.H.4
  • 87
    • 33947282181 scopus 로고    scopus 로고
    • Epidermal growth factor 61 A/G polymorphism and uterine cervical cancer
    • Kang S, Kim JW, Park NH et al. Epidermal growth factor 61 A/G polymorphism and uterine cervical cancer. Int J Gynecol Cancer 2007; 17: 492-496.
    • (2007) Int J Gynecol Cancer , vol.17 , pp. 492-496
    • Kang, S.1    Kim, J.W.2    Park, N.H.3
  • 88
    • 0037498546 scopus 로고    scopus 로고
    • Detection of epidermal growth factor receptor mRNA in peripheral blood of cervical cancer patients
    • Mitsuhashi A, Tanaka N, Suzuka K et al. Detection of epidermal growth factor receptor mRNA in peripheral blood of cervical cancer patients. Gynecol Oncol 2003; 89: 480-485.
    • (2003) Gynecol Oncol , vol.89 , pp. 480-485
    • Mitsuhashi, A.1    Tanaka, N.2    Suzuka, K.3
  • 89
    • 0022656554 scopus 로고
    • Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas
    • Gullick WJ, Marsden JJ, Whittle N et al. Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas. Cancer Res 1986; 46: 285-292.
    • (1986) Cancer Res , vol.46 , pp. 285-292
    • Gullick, W.J.1    Marsden, J.J.2    Whittle, N.3
  • 90
    • 3242875792 scopus 로고    scopus 로고
    • Intratumor chromosomal heterogeneity in advanced carcinomas of the uterine cervix
    • Lyng H, Beigi M, Svendsrud DH et al. Intratumor chromosomal heterogeneity in advanced carcinomas of the uterine cervix. Int J Cancer 2004; 111: 358-366.
    • (2004) Int J Cancer , vol.111 , pp. 358-366
    • Lyng, H.1    Beigi, M.2    Svendsrud, D.H.3
  • 91
    • 78751582338 scopus 로고    scopus 로고
    • Cetuximab monotherapy in advanced cervical cancer: a retrospective study with five patients
    • Hertlein L, Lenhard M, Kirschenhofer A et al. Cetuximab monotherapy in advanced cervical cancer: a retrospective study with five patients. Arch Gynecol Obstet 2011; 283: 109-113.
    • (2011) Arch Gynecol Obstet , vol.283 , pp. 109-113
    • Hertlein, L.1    Lenhard, M.2    Kirschenhofer, A.3
  • 92
    • 37449004176 scopus 로고    scopus 로고
    • A phase II trial to evaluate gefitinib as second- or third-line treatment in patients with recurring locoregionally advanced or metastatic cervical cancer
    • Goncalves A, Fabbro M, Lhomme C et al. A phase II trial to evaluate gefitinib as second- or third-line treatment in patients with recurring locoregionally advanced or metastatic cervical cancer. Gynecol Oncol 2008; 108: 42-46.
    • (2008) Gynecol Oncol , vol.108 , pp. 42-46
    • Goncalves, A.1    Fabbro, M.2    Lhomme, C.3
  • 93
    • 77649193788 scopus 로고    scopus 로고
    • Lack in efficacy for imatinib mesylate as second-line treatment of recurrent or metastatic cervical cancer expressing platelet-derived growth factor receptor alpha
    • Candelaria M, Arias-Bonfill D, Chavez-Blanco A et al. Lack in efficacy for imatinib mesylate as second-line treatment of recurrent or metastatic cervical cancer expressing platelet-derived growth factor receptor alpha. Int J Gynecol Cancer 2009; 19: 1632-1637.
    • (2009) Int J Gynecol Cancer , vol.19 , pp. 1632-1637
    • Candelaria, M.1    Arias-Bonfill, D.2    Chavez-Blanco, A.3
  • 94
    • 77955874058 scopus 로고    scopus 로고
    • Phase II, open-label study of pazopanib or lapatinib monotherapy compared with pazopanib plus lapatinib combination therapy in patients with advanced and recurrent cervical cancer
    • Monk BJ, Mas Lopez L, Zarba JJ et al. Phase II, open-label study of pazopanib or lapatinib monotherapy compared with pazopanib plus lapatinib combination therapy in patients with advanced and recurrent cervical cancer. J Clin Oncol 2010; 28: 3562-3569.
    • (2010) J Clin Oncol , vol.28 , pp. 3562-3569
    • Monk, B.J.1    Mas Lopez, L.2    Zarba, J.J.3
  • 95
    • 33750203160 scopus 로고    scopus 로고
    • Expression of platelet derived growth factor family members and the potential role of imatinib mesylate for cervical cancer
    • Taja-Chayeb L, Chavez-Blanco A, Martinez-Tlahuel J et al. Expression of platelet derived growth factor family members and the potential role of imatinib mesylate for cervical cancer. Cancer Cell Int 2006; 6: 22.
    • (2006) Cancer Cell Int , vol.6 , pp. 22
    • Taja-Chayeb, L.1    Chavez-Blanco, A.2    Martinez-Tlahuel, J.3
  • 96
    • 2642574285 scopus 로고    scopus 로고
    • Overexpression of c-kit protein is an infrequent event in small cell carcinomas of the uterine cervix
    • Wang HL, Lu DW. Overexpression of c-kit protein is an infrequent event in small cell carcinomas of the uterine cervix. Mod Pathol 2004; 17: 732-738.
    • (2004) Mod Pathol , vol.17 , pp. 732-738
    • Wang, H.L.1    Lu, D.W.2
  • 97
    • 73949095460 scopus 로고    scopus 로고
    • Phase II evaluation of cisplatin plus cetuximab in the treatment of recurrent and persistent cancers of the cervix: a limited access phase II study of the Gynecologic Oncology Group
    • Farley JH, Sill M, Walker JL et al. Phase II evaluation of cisplatin plus cetuximab in the treatment of recurrent and persistent cancers of the cervix: a limited access phase II study of the Gynecologic Oncology Group. J Clin Oncol 2009; 27: A5521.
    • (2009) J Clin Oncol , vol.27
    • Farley, J.H.1    Sill, M.2    Walker, J.L.3
  • 98
    • 62749156047 scopus 로고    scopus 로고
    • Cetuximab, topotecan and cisplatin for the treatment of advanced cervical cancer: a phase II GINECO trial
    • Kurtz JE, Hardy-Bessard AC, Deslandres M et al. Cetuximab, topotecan and cisplatin for the treatment of advanced cervical cancer: a phase II GINECO trial. Gynecol Oncol 2009; 113: 16-20.
    • (2009) Gynecol Oncol , vol.113 , pp. 16-20
    • Kurtz, J.E.1    Hardy-Bessard, A.C.2    Deslandres, M.3
  • 99
    • 77954767460 scopus 로고    scopus 로고
    • Erlotinib (E) combined with cisplatin (C) and radiotherapy (RT) for patients with locally advanced squamous cell cervical cancer: a phase II trial
    • Ferreira CG, Erlich F, Carmo CC et al. Erlotinib (E) combined with cisplatin (C) and radiotherapy (RT) for patients with locally advanced squamous cell cervical cancer: a phase II trial. J Clin Oncol 2008: 26 (Abstr 5511).
    • (2008) J Clin Oncol , vol.26
    • Ferreira, C.G.1    Erlich, F.2    Carmo, C.C.3
  • 100
    • 58149151263 scopus 로고    scopus 로고
    • Phase I trial of erlotinib combined with cisplatin and radiotherapy for patients with locally advanced cervical squamous cell cancer
    • Nogueira-Rodrigues A, do Carmo CC, Viegas C et al. Phase I trial of erlotinib combined with cisplatin and radiotherapy for patients with locally advanced cervical squamous cell cancer. Clin Cancer Res 2008; 14: 6324-6329.
    • (2008) Clin Cancer Res , vol.14 , pp. 6324-6329
    • Nogueira-Rodrigues, A.1    do Carmo, C.C.2    Viegas, C.3


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