Sex and age modify biochemical and skeletal manifestations of chronic hyperparathyroidism by altering target organ responses to Ca2+ and parathyroid hormone in mice

Journal of Bone and Mineral Research

Volumn 28, Issue 5, 2013, Pages 1087-1100

  Cheng, Zhiqiang ^a   Liang, Nathan ^a   Chen, Tsui Hua ^a   Li, Alfred ^a   Santa Maria, Christian ^a   You, Michael ^a   Ho, Hanson ^a   Song, Fuqing ^a   Bikle, Daniel ^a   Tu, Chialing ^a   Shoback, Dolores ^a   Chang, Wenhan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Bone Histomorphometry; bone, Skeletal Anabolism; Ca2+ Set point; casr; cyp27b1; Extracellular Calcium sensing Receptor; Gender; Micro computed Tomography; Mouse Model; Parathyroid Gland; Parathyroid Gland Culture; Parathyroid Hormone; Primary Hyperparathyroidism; Pth Secretion; Sex; Skeletal Catabolism

Indexed keywords

CALCITRIOL; CALCIUM ION; CALCIUM SENSING RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 27B1; PARATHYROID HORMONE; RNA; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOSYNTHESIS; BONE MINERAL; CALCIUM TRANSPORT; CHRONIC HYPERPARATHYROIDISM; CONTROLLED STUDY; CORTICAL BONE; FEMALE; GENE EXPRESSION; HOMEOSTASIS; HYPERPARATHYROIDISM; INTESTINE; KIDNEY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; CALCIUM; CHRONIC DISEASE; FEMALE; HYPERPARATHYROIDISM; MALE; MICE; MICE, KNOCKOUT; PARATHYROID HORMONE; POLYMERASE CHAIN REACTION; RECEPTORS, CALCIUM-SENSING; SEX FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84876727452     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1846     Document Type: Article

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