-
1
-
-
0036500022
-
ErbB2 expression is correlated with increased survival of patients with osteosarcoma
-
Akatsuka T., et al. ErbB2 expression is correlated with increased survival of patients with osteosarcoma. Cancer 2002, 94:1397-1404.
-
(2002)
Cancer
, vol.94
, pp. 1397-1404
-
-
Akatsuka, T.1
-
2
-
-
0029053716
-
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas
-
Alimandi M., et al. Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 1995, 10:1813-1821.
-
(1995)
Oncogene
, vol.10
, pp. 1813-1821
-
-
Alimandi, M.1
-
3
-
-
1942453293
-
Overexpression of the HER-2 oncogene does not play a role in high-grade osteosarcomas
-
Anninga J.K., et al. Overexpression of the HER-2 oncogene does not play a role in high-grade osteosarcomas. Eur. J. Cancer 2004, 40:963-970.
-
(2004)
Eur. J. Cancer
, vol.40
, pp. 963-970
-
-
Anninga, J.K.1
-
4
-
-
79959228980
-
The molecular pathogenesis of osteosarcoma: a review
-
Broadhead M.L., Clark J.C., Myers D.E., Dass C.R., Choong P.F. The molecular pathogenesis of osteosarcoma: a review. Sarcoma 2011, 2011:959248.
-
(2011)
Sarcoma
, vol.2011
, pp. 959248
-
-
Broadhead, M.L.1
Clark, J.C.2
Myers, D.E.3
Dass, C.R.4
Choong, P.F.5
-
5
-
-
0035313702
-
Localization and modulation of ErbB receptor tyrosine kinases
-
Carraway K.L., Sweeney C. Localization and modulation of ErbB receptor tyrosine kinases. Curr. Opin. Cell Biol. 2001, 13:125-130.
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 125-130
-
-
Carraway, K.L.1
Sweeney, C.2
-
6
-
-
34547122493
-
A secreted isoform of ErbB3 promotes osteonectin expression in bone and enhances the invasiveness of prostate cancer cells
-
Chen N., et al. A secreted isoform of ErbB3 promotes osteonectin expression in bone and enhances the invasiveness of prostate cancer cells. Cancer Res. 2007, 67:6544-6548.
-
(2007)
Cancer Res.
, vol.67
, pp. 6544-6548
-
-
Chen, N.1
-
7
-
-
33745828702
-
EGF-ERBB signalling: towards the systems level
-
Citri A., Yarden Y. EGF-ERBB signalling: towards the systems level. Nat. Rev. Mol. Cell Biol. 2006, 7:505-516.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
8
-
-
32444446273
-
Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation
-
Contessa J.N., Abell A., Mikkelsen R.B., Valerie K., Schmidt-Ullrich R.K. Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation. Breast Cancer Res. Treat. 2006, 95:17-27.
-
(2006)
Breast Cancer Res. Treat.
, vol.95
, pp. 17-27
-
-
Contessa, J.N.1
Abell, A.2
Mikkelsen, R.B.3
Valerie, K.4
Schmidt-Ullrich, R.K.5
-
9
-
-
79957915754
-
ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis
-
Cook R.S., et al. ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis. Cancer Res. 2011, 71:3941-3951.
-
(2011)
Cancer Res.
, vol.71
, pp. 3941-3951
-
-
Cook, R.S.1
-
10
-
-
0029912514
-
Increased bone formation and osteoblastic cell phenotype in premature cranial suture ossification (craniosynostosis)
-
De Pollack C., Renier D., Hott M., Marie P.J. Increased bone formation and osteoblastic cell phenotype in premature cranial suture ossification (craniosynostosis). J. Bone Miner. Res. 1996, 11:401-407.
-
(1996)
J. Bone Miner. Res.
, vol.11
, pp. 401-407
-
-
De Pollack, C.1
Renier, D.2
Hott, M.3
Marie, P.J.4
-
11
-
-
84866672444
-
Targeted inhibition of T-cell factor activity promotes syndecan-2 expression and sensitization to doxorubicin in osteosarcoma cells and bone tumors in mice
-
Dieudonné F.X., Marion A., Marie P.J., Modrowski D. Targeted inhibition of T-cell factor activity promotes syndecan-2 expression and sensitization to doxorubicin in osteosarcoma cells and bone tumors in mice. J. Bone Miner. Res. 2012, 27:2118-2129.
-
(2012)
J. Bone Miner. Res.
, vol.27
, pp. 2118-2129
-
-
Dieudonné, F.X.1
Marion, A.2
Marie, P.J.3
Modrowski, D.4
-
12
-
-
34547465203
-
Requirement for ErbB2/ErbB signaling in developing cartilage and bone
-
Fisher M.C., Clinton G.M., Maihle N.J., Dealy C.N. Requirement for ErbB2/ErbB signaling in developing cartilage and bone. Dev. Growth Differ. 2007, 49:503-513.
-
(2007)
Dev. Growth Differ.
, vol.49
, pp. 503-513
-
-
Fisher, M.C.1
Clinton, G.M.2
Maihle, N.J.3
Dealy, C.N.4
-
13
-
-
33749637920
-
RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation
-
Fromigué O., et al. RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation. Cell Death Differ. 2006, 13:1845-1856.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1845-1856
-
-
Fromigué, O.1
-
14
-
-
57649217290
-
Blockade of the RhoA-JNK-c-Jun-MMP2 cascade by atorvastatin reduces osteosarcoma cell invasion
-
Fromigué O., Hamidouche Z., Marie P.J. Blockade of the RhoA-JNK-c-Jun-MMP2 cascade by atorvastatin reduces osteosarcoma cell invasion. J. Biol. Chem. 2008, 283:30549-30556.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 30549-30556
-
-
Fromigué, O.1
Hamidouche, Z.2
Marie, P.J.3
-
15
-
-
70350150140
-
Critical signaling pathways in bone sarcoma: candidates for therapeutic interventions
-
Geryk-Hall M., Hughes D.P. Critical signaling pathways in bone sarcoma: candidates for therapeutic interventions. Curr. Oncol. Rep. 2009, 11:446-453.
-
(2009)
Curr. Oncol. Rep.
, vol.11
, pp. 446-453
-
-
Geryk-Hall, M.1
Hughes, D.P.2
-
16
-
-
0031878385
-
Osteosarcoma and other bone cancers
-
Himelstein B.P. Osteosarcoma and other bone cancers. Curr. Opin. Oncol. 1998, 10:326-333.
-
(1998)
Curr. Opin. Oncol.
, vol.10
, pp. 326-333
-
-
Himelstein, B.P.1
-
17
-
-
0042307325
-
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
-
Holbro T., Beerli R.R., Maurer F., Koziczak M., Barbas C.F., Hynes N.E. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:8933-8938.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 8933-8938
-
-
Holbro, T.1
Beerli, R.R.2
Maurer, F.3
Koziczak, M.4
Barbas, C.F.5
Hynes, N.E.6
-
18
-
-
1542615081
-
Cell surface expression of epidermal growth factor receptor and Her-2 with nuclear expression of Her-4 in primary osteosarcoma
-
Hughes D.P., Thomas D.G., Giordano T.J., Baker L.H., McDonagh K.T. Cell surface expression of epidermal growth factor receptor and Her-2 with nuclear expression of Her-4 in primary osteosarcoma. Cancer Res. 2004, 64:2047-2053.
-
(2004)
Cancer Res.
, vol.64
, pp. 2047-2053
-
-
Hughes, D.P.1
Thomas, D.G.2
Giordano, T.J.3
Baker, L.H.4
McDonagh, K.T.5
-
19
-
-
33645322113
-
Essential erbB family phosphorylation in osteosarcoma as a target for CI-1033 inhibition
-
Hughes D.P., Thomas D.G., Giordano T.J., McDonagh K.T., Baker L.H. Essential erbB family phosphorylation in osteosarcoma as a target for CI-1033 inhibition. Pediatr. Blood Cancer 2006, 46:614-623.
-
(2006)
Pediatr. Blood Cancer
, vol.46
, pp. 614-623
-
-
Hughes, D.P.1
Thomas, D.G.2
Giordano, T.J.3
McDonagh, K.T.4
Baker, L.H.5
-
20
-
-
0034788982
-
The ErbB receptor tyrosine family as signal integrators
-
Hynes N.E., Horsch K., Olayioye M.A., Badache A. The ErbB receptor tyrosine family as signal integrators. Endocr. Relat. Cancer 2001, 8:151-159.
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 151-159
-
-
Hynes, N.E.1
Horsch, K.2
Olayioye, M.A.3
Badache, A.4
-
21
-
-
77953669077
-
Osteosarcoma: review of the past, impact on the future. The American experience
-
Jaffe N. Osteosarcoma: review of the past, impact on the future. The American experience. Cancer Treat. Res. 2009, 152:239-262.
-
(2009)
Cancer Treat. Res.
, vol.152
, pp. 239-262
-
-
Jaffe, N.1
-
22
-
-
84859577298
-
Downregulation of ErbB3 By Wnt3a contributes to Wnt-induced osteoblast differentiation in mesenchymal cells
-
Jullien N., Maudinet A., Leloutre B., Ringe J., Haupl T., Marie P.J. Downregulation of ErbB3 By Wnt3a contributes to Wnt-induced osteoblast differentiation in mesenchymal cells. J. Cell. Biochem. 2012, 113:2047-2056.
-
(2012)
J. Cell. Biochem.
, vol.113
, pp. 2047-2056
-
-
Jullien, N.1
Maudinet, A.2
Leloutre, B.3
Ringe, J.4
Haupl, T.5
Marie, P.J.6
-
23
-
-
0035057571
-
An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential
-
Khanna C., Prehn J., Yeung C., Caylor J., Tsokos M., Helman L. An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential. Clin. Exp. Metastasis 2000, 18:261-271.
-
(2000)
Clin. Exp. Metastasis
, vol.18
, pp. 261-271
-
-
Khanna, C.1
Prehn, J.2
Yeung, C.3
Caylor, J.4
Tsokos, M.5
Helman, L.6
-
24
-
-
0037422206
-
Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas
-
Kobayashi M., Iwamatsu A., Shinohara-Kanda A., Ihara S., Fukui Y. Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas. Oncogene 2003, 22:1294-1301.
-
(2003)
Oncogene
, vol.22
, pp. 1294-1301
-
-
Kobayashi, M.1
Iwamatsu, A.2
Shinohara-Kanda, A.3
Ihara, S.4
Fukui, Y.5
-
25
-
-
43049095679
-
Platelet-derived growth factor receptor as a prognostic marker and a therapeutic target for imatinib mesylate therapy in osteosarcoma
-
Kubo T., et al. Platelet-derived growth factor receptor as a prognostic marker and a therapeutic target for imatinib mesylate therapy in osteosarcoma. Cancer 2008, 112:2119-2129.
-
(2008)
Cancer
, vol.112
, pp. 2119-2129
-
-
Kubo, T.1
-
26
-
-
41949100690
-
Clinical implications of the ErbB/epidermal growth factor (EGF) receptor family and its ligands in ovarian cancer
-
Lafky J.M., Wilken J.A., Baron A.T., Maihle N.J. Clinical implications of the ErbB/epidermal growth factor (EGF) receptor family and its ligands in ovarian cancer. Biochim. Biophys. Acta 2008, 1785:232-265.
-
(2008)
Biochim. Biophys. Acta
, vol.1785
, pp. 232-265
-
-
Lafky, J.M.1
Wilken, J.A.2
Baron, A.T.3
Maihle, N.J.4
-
27
-
-
77953143213
-
A meta-analysis on the association of HER-2 overexpression with prognosis in human osteosarcoma
-
Li Y.G., Geng X. A meta-analysis on the association of HER-2 overexpression with prognosis in human osteosarcoma. Eur. J. Cancer Care (Engl.) 2010, 19:313-316.
-
(2010)
Eur. J. Cancer Care (Engl.)
, vol.19
, pp. 313-316
-
-
Li, Y.G.1
Geng, X.2
-
28
-
-
52449112465
-
Soluble ErbB3 levels in bone marrow and plasma of men with prostate cancer
-
Lin S.H., et al. Soluble ErbB3 levels in bone marrow and plasma of men with prostate cancer. Clin. Cancer Res. 2008, 14:3729-3736.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3729-3736
-
-
Lin, S.H.1
-
29
-
-
5444242379
-
IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma
-
MacEwen E.G., et al. IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma. J. Cell. Biochem. 2004, 92:77-91.
-
(2004)
J. Cell. Biochem.
, vol.92
, pp. 77-91
-
-
MacEwen, E.G.1
-
30
-
-
80052324818
-
The Wnt signaling pathway: implications for therapy in osteosarcoma
-
McQueen P., Ghaffar S., Guo Y., Rubin E.M., Zi X., Hoang B.H. The Wnt signaling pathway: implications for therapy in osteosarcoma. Expert Rev. Anticancer Ther. 2011, 11:1223-1232.
-
(2011)
Expert Rev. Anticancer Ther.
, vol.11
, pp. 1223-1232
-
-
McQueen, P.1
Ghaffar, S.2
Guo, Y.3
Rubin, E.M.4
Zi, X.5
Hoang, B.H.6
-
31
-
-
3042611780
-
Oncogenic growth factor receptors: implications for signal transduction therapy
-
Mosesson Y., Yarden Y. Oncogenic growth factor receptors: implications for signal transduction therapy. Semin. Cancer Biol. 2004, 14:262-270.
-
(2004)
Semin. Cancer Biol.
, vol.14
, pp. 262-270
-
-
Mosesson, Y.1
Yarden, Y.2
-
32
-
-
0031730476
-
Expression of c-erbB3 protein in primary breast carcinomas
-
Naidu R., Yadav M., Nair S., Kutty M.K. Expression of c-erbB3 protein in primary breast carcinomas. Br. J. Cancer 1998, 78:1385-1390.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1385-1390
-
-
Naidu, R.1
Yadav, M.2
Nair, S.3
Kutty, M.K.4
-
33
-
-
13344285355
-
ErbB-2 expression is correlated with poor prognosis for patients with osteosarcoma
-
Onda M., et al. ErbB-2 expression is correlated with poor prognosis for patients with osteosarcoma. Cancer 1996, 77:71-78.
-
(1996)
Cancer
, vol.77
, pp. 71-78
-
-
Onda, M.1
-
35
-
-
32844464858
-
Prognostic and predictive value of c-erbB2 overexpression in osteogenic sarcoma
-
Rakesh Kumar V., Gupta N., Kakkar N., Sharma S.C. Prognostic and predictive value of c-erbB2 overexpression in osteogenic sarcoma. J. Cancer Res. Ther. 2006, 2:20-23.
-
(2006)
J. Cancer Res. Ther.
, vol.2
, pp. 20-23
-
-
Rakesh Kumar, V.1
Gupta, N.2
Kakkar, N.3
Sharma, S.C.4
-
36
-
-
33745959940
-
Constitutive activation of neuregulin/ERBB3 signaling pathway in clear cell sarcoma of soft tissue
-
Schaefer K.L., et al. Constitutive activation of neuregulin/ERBB3 signaling pathway in clear cell sarcoma of soft tissue. Neoplasia 2006, 8:613-622.
-
(2006)
Neoplasia
, vol.8
, pp. 613-622
-
-
Schaefer, K.L.1
-
37
-
-
77950216941
-
An ErbB3 antibody, MM-121, is active in cancers with ligand-dependent activation
-
Schoeberl B., et al. An ErbB3 antibody, MM-121, is active in cancers with ligand-dependent activation. Cancer Res. 2010, 70:2485-2494.
-
(2010)
Cancer Res.
, vol.70
, pp. 2485-2494
-
-
Schoeberl, B.1
-
38
-
-
84866668120
-
Targeting the E3 ubiquitin casitas B-lineage lymphoma decreases osteosarcoma cell growth and survival and reduces tumorigenesis
-
Sévère N., et al. Targeting the E3 ubiquitin casitas B-lineage lymphoma decreases osteosarcoma cell growth and survival and reduces tumorigenesis. J. Bone Miner. Res. 2012, 27:2108-2117.
-
(2012)
J. Bone Miner. Res.
, vol.27
, pp. 2108-2117
-
-
Sévère, N.1
-
39
-
-
77649314140
-
An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells
-
Sheng Q., et al. An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells. Cancer Cell 2010, 17:298-310.
-
(2010)
Cancer Cell
, vol.17
, pp. 298-310
-
-
Sheng, Q.1
-
40
-
-
44949141721
-
The ERBB3 receptor in cancer and cancer gene therapy
-
Sithanandam G., Anderson L.M. The ERBB3 receptor in cancer and cancer gene therapy. Cancer Gene Ther. 2008, 15:413-448.
-
(2008)
Cancer Gene Ther.
, vol.15
, pp. 413-448
-
-
Sithanandam, G.1
Anderson, L.M.2
-
41
-
-
0142247523
-
Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathway
-
Sithanandam G., Smith G.T., Masuda A., Takahashi T., Anderson L.M., Fornwald L.W. Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathway. Carcinogenesis 2003, 24:1581-1592.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1581-1592
-
-
Sithanandam, G.1
Smith, G.T.2
Masuda, A.3
Takahashi, T.4
Anderson, L.M.5
Fornwald, L.W.6
-
42
-
-
16244409820
-
Inactivation of ErbB3 by siRNA promotes apoptosis and attenuates growth and invasiveness of human lung adenocarcinoma cell line A549
-
Sithanandam G., Fornwald L.W., Fields J., Anderson L.M. Inactivation of ErbB3 by siRNA promotes apoptosis and attenuates growth and invasiveness of human lung adenocarcinoma cell line A549. Oncogene 2005, 24:1847-1859.
-
(2005)
Oncogene
, vol.24
, pp. 1847-1859
-
-
Sithanandam, G.1
Fornwald, L.W.2
Fields, J.3
Anderson, L.M.4
-
43
-
-
70350724564
-
HER3 is required for the maintenance of neuregulin-dependent and -independent attributes of malignant progression in prostate cancer cells
-
Soler M., et al. HER3 is required for the maintenance of neuregulin-dependent and -independent attributes of malignant progression in prostate cancer cells. Int. J. Cancer 2009, 125:2565-2575.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 2565-2575
-
-
Soler, M.1
-
44
-
-
50649112829
-
Osteosarcoma development and stem cell differentiation
-
Tang N., Song W.X., Luo J., Haydon R.C., He T.C. Osteosarcoma development and stem cell differentiation. Clin. Orthop. Relat. Res. 2008, 466:2114-2130.
-
(2008)
Clin. Orthop. Relat. Res.
, vol.466
, pp. 2114-2130
-
-
Tang, N.1
Song, W.X.2
Luo, J.3
Haydon, R.C.4
He, T.C.5
-
45
-
-
0036307708
-
Absence of HER2/neu gene expression in osteosarcoma and skeletal Ewing's sarcoma
-
Thomas D.G., Giordano T.J., Sanders D., Biermann J.S., Baker L. Absence of HER2/neu gene expression in osteosarcoma and skeletal Ewing's sarcoma. Clin. Cancer Res. 2002, 8:788-793.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 788-793
-
-
Thomas, D.G.1
Giordano, T.J.2
Sanders, D.3
Biermann, J.S.4
Baker, L.5
-
46
-
-
2642532758
-
Up-regulation of MDA-BF-1, a secreted isoform of ErbB3, in metastatic prostate cancer cells and activated osteoblasts in bone marrow
-
Vakar-Lopez F., et al. Up-regulation of MDA-BF-1, a secreted isoform of ErbB3, in metastatic prostate cancer cells and activated osteoblasts in bone marrow. J. Pathol. 2004, 203:688-695.
-
(2004)
J. Pathol.
, vol.203
, pp. 688-695
-
-
Vakar-Lopez, F.1
-
47
-
-
32944465535
-
ErbB3-dependent motility and intravasation in breast cancer metastasis
-
Xue C., et al. ErbB3-dependent motility and intravasation in breast cancer metastasis. Cancer Res. 2006, 66:1418-1426.
-
(2006)
Cancer Res.
, vol.66
, pp. 1418-1426
-
-
Xue, C.1
-
49
-
-
34547676475
-
ErbB receptors: from oncogenes to targeted cancer therapies
-
Zhang H., et al. ErbB receptors: from oncogenes to targeted cancer therapies. J. Clin. Invest. 2007, 117:2051-2058.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2051-2058
-
-
Zhang, H.1
|