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Volumn 95, Issue 1, 2006, Pages 17-27

Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation

Author keywords

Apoptosis; c Src; EGFR; ErbB3 Her3

Indexed keywords

ADENOVIRUS VECTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; MUTANT PROTEIN; PROTEIN BCL XL; PROTEIN TYROSINE KINASE;

EID: 32444446273     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-005-9023-9     Document Type: Article
Times cited : (37)

References (48)
  • 1
    • 0037115674 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
    • Ang KK, Berkey BA, Tu X, Zhang HZ, Katz R, Hammond EH, Fu KK, Milas L: Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 62: 7350-7356, 2002
    • (2002) Cancer Res , vol.62 , pp. 7350-7356
    • Ang, K.K.1    Berkey, B.A.2    Tu, X.3    Zhang, H.Z.4    Katz, R.5    Hammond, E.H.6    Fu, K.K.7    Milas, L.8
  • 2
    • 0037285971 scopus 로고    scopus 로고
    • Growth factor receptors in breast cancer: Potential for therapeutic intervention
    • Nahta R, Hortobagyi GN, Esteva FJ: Growth factor receptors in breast cancer: potential for therapeutic intervention. Oncologist 8: 5-17, 2003
    • (2003) Oncologist , vol.8 , pp. 5-17
    • Nahta, R.1    Hortobagyi, G.N.2    Esteva, F.J.3
  • 4
    • 0033546315 scopus 로고    scopus 로고
    • ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases
    • Olayioye MA, Beuvink I, Horsch K, Daly JM, Hynes NE: ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases. J Biol Chem 274: 17209-17218, 1999
    • (1999) J Biol Chem , vol.274 , pp. 17209-17218
    • Olayioye, M.A.1    Beuvink, I.2    Horsch, K.3    Daly, J.M.4    Hynes, N.E.5
  • 5
    • 0034693801 scopus 로고    scopus 로고
    • Ligand discrimination by ErbB receptors: Differential signaling through differential phosphorylation site usage
    • Sweeney C, Carraway 3rd. KL: Ligand discrimination by ErbB receptors: differential signaling through differential phosphorylation site usage. Oncogene 19: 5568-5573, 2000
    • (2000) Oncogene , vol.19 , pp. 5568-5573
    • Sweeney, C.1    Carraway III, K.L.2
  • 6
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
    • Graus-Porta D, Beerli RR, Daly JM, Hynes NE: ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 16: 1647-1655, 1997
    • (1997) EMBO J , vol.16 , pp. 1647-1655
    • Graus-Porta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.E.4
  • 8
    • 0030973939 scopus 로고    scopus 로고
    • Biochemical characterization of the protein tyrosine kinase homology domain of the ErbB3 (HER3) receptor protein
    • Sierke SL, Cheng K, Kim HH, Koland JG: Biochemical characterization of the protein tyrosine kinase homology domain of the ErbB3 (HER3) receptor protein. Biochem J. 322: 757-763, 1997
    • (1997) Biochem J , vol.322 , pp. 757-763
    • Sierke, S.L.1    Cheng, K.2    Kim, H.H.3    Koland, J.G.4
  • 9
    • 0032571234 scopus 로고    scopus 로고
    • Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3
    • Fiddes RJ, Campbell DH, Janes PW, Sivertsen SP, Sasaki H, Wallasch C, Daly RJ: Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3. J Biol Chem 273: 7717-7724, 1998
    • (1998) J Biol Chem , vol.273 , pp. 7717-7724
    • Fiddes, R.J.1    Campbell, D.H.2    Janes, P.W.3    Sivertsen, S.P.4    Sasaki, H.5    Wallasch, C.6    Daly, R.J.7
  • 10
    • 0032142749 scopus 로고    scopus 로고
    • Erb-b3 (Her 3) Interaction with the p85 regulatory subunit of phosphoinositide 3 kinase
    • Hellyer N, Kunrong C, Koland J: Erb-b3 (Her 3) Interaction with the p85 regulatory subunit of phosphoinositide 3 kinase. Biochem J 333: 757-763, 1998
    • (1998) Biochem J , vol.333 , pp. 757-763
    • Hellyer, N.1    Kunrong, C.2    Koland, J.3
  • 11
    • 0037291769 scopus 로고    scopus 로고
    • EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization
    • Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA: EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol Cell 11: 507-517, 2003
    • (2003) Mol Cell , vol.11 , pp. 507-517
    • Ferguson, K.M.1    Berger, M.B.2    Mendrola, J.M.3    Cho, H.S.4    Leahy, D.J.5    Lemmon, M.A.6
  • 15
    • 0037162799 scopus 로고    scopus 로고
    • Structure of the extracellular region of HER3 reveals an interdomain tether
    • Cho HS, Leahy DJ: Structure of the extracellular region of HER3 reveals an interdomain tether. Science 297: 1330-1333, 2002
    • (2002) Science , vol.297 , pp. 1330-1333
    • Cho, H.S.1    Leahy, D.J.2
  • 16
    • 0037145061 scopus 로고    scopus 로고
    • Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
    • Schlessinger J: Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 110: 669-672, 2002
    • (2002) Cell , vol.110 , pp. 669-672
    • Schlessinger, J.1
  • 17
    • 0026058365 scopus 로고
    • A dominant negative mutation supresses the function of normal epidermal growth factor receptors by heterodimerization
    • Kashles O, Yarden Y, Fischer R, Ullrich A, Schlessinger J: A dominant negative mutation supresses the function of normal epidermal growth factor receptors by heterodimerization. Mol Cell Biol 11: 1454-1463, 1991
    • (1991) Mol Cell Biol , vol.11 , pp. 1454-1463
    • Kashles, O.1    Yarden, Y.2    Fischer, R.3    Ullrich, A.4    Schlessinger, J.5
  • 19
    • 0033534459 scopus 로고    scopus 로고
    • Domain-specific interactions between the p185(neu) and epidermal growth factor receptor kinases determine differential signaling outcomes
    • Qian X, O'Rourke DM, Fei Z, Zhang HT, Kao CC, Greene MI: Domain-specific interactions between the p185(neu) and epidermal growth factor receptor kinases determine differential signaling outcomes. J Biol Chem 274: 574-583, 1999
    • (1999) J Biol Chem , vol.274 , pp. 574-583
    • Qian, X.1    O'Rourke, D.M.2    Fei, Z.3    Zhang, H.T.4    Kao, C.C.5    Greene, M.I.6
  • 20
    • 0033542381 scopus 로고    scopus 로고
    • Expression of dominant-negative ErbB2 in the mammary gland of transgenic mice reveals a role in lobuloalveolar development and lactation
    • Jones FE, Stern DF: Expression of dominant-negative ErbB2 in the mammary gland of transgenic mice reveals a role in lobuloalveolar development and lactation. Oncogene 18: 3481-3490, 1999
    • (1999) Oncogene , vol.18 , pp. 3481-3490
    • Jones, F.E.1    Stern, D.F.2
  • 21
    • 0026700010 scopus 로고
    • Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses
    • Spivak-Kroizman T, Rotin D, Pinchasi D, Ullrich A, Schlessinger J, Lax I: Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses. J Biol Chem 267: 8056-8063, 1992
    • (1992) J Biol Chem , vol.267 , pp. 8056-8063
    • Spivak-Kroizman, T.1    Rotin, D.2    Pinchasi, D.3    Ullrich, A.4    Schlessinger, J.5    Lax, I.6
  • 22
    • 0028156927 scopus 로고
    • Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: A mechanism of interreceptor kinase activation and transphosphorylation
    • USA
    • Qian X, LeVea CM, Freeman JK, Dougall WC, Greene MI: Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation. Proc Natl Acad Sci USA 91: 1500-1504, 1994
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 1500-1504
    • Qian, X.1    LeVea, C.M.2    Freeman, J.K.3    Dougall, W.C.4    Greene, M.I.5
  • 25
    • 0036606779 scopus 로고    scopus 로고
    • The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides
    • Motoyama AB, Hynes NE, Lane HA: The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides. Cancer Res 62: 3151-3158, 2002
    • (2002) Cancer Res , vol.62 , pp. 3151-3158
    • Motoyama, A.B.1    Hynes, N.E.2    Lane, H.A.3
  • 27
    • 0033573921 scopus 로고    scopus 로고
    • Mechanisms of biological synergy between cellular Src and EGFR
    • Tice D, Biscardi J, Nickles A, Parsons S: Mechanisms of biological synergy between cellular Src and EGFR. Proc Nat Acad Sci 96: 1415-1420, 1999
    • (1999) Proc Nat Acad Sci , vol.96 , pp. 1415-1420
    • Tice, D.1    Biscardi, J.2    Nickles, A.3    Parsons, S.4
  • 28
    • 0033584297 scopus 로고    scopus 로고
    • Inhibition of pp60c-Src reduces Bel-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors
    • Karni R, Jove R, Levitzki A: Inhibition of pp60c-Src reduces Bel-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors. Oncogene 18: 4654-4662, 1999
    • (1999) Oncogene , vol.18 , pp. 4654-4662
    • Karni, R.1    Jove, R.2    Levitzki, A.3
  • 29
    • 0033542379 scopus 로고    scopus 로고
    • NDF/heregulin-induced cell cycle changes and apoptosis in breast tumour cells: Role of PI3 kinase and p38 MAP kinase pathways
    • Daly JM, Olayioye MA, Wong AM, Neve R, Lane HA, Maurer FG, Hynes NE: NDF/heregulin-induced cell cycle changes and apoptosis in breast tumour cells: role of PI3 kinase and p38 MAP kinase pathways. Oncogene 18: 3440-3451, 1999
    • (1999) Oncogene , vol.18 , pp. 3440-3451
    • Daly, J.M.1    Olayioye, M.A.2    Wong, A.M.3    Neve, R.4    Lane, H.A.5    Maurer, F.G.6    Hynes, N.E.7
  • 30
    • 0033935125 scopus 로고    scopus 로고
    • Improved radiosensitization of rat glioma cells with adenovirus-expressed mutant herpes simplex virus-thymidine kinase in combination with acyclovir
    • Valerie K, Brust D, Farnsworth J, Amir C, Taher MM, Hershey C, Feden J: Improved radiosensitization of rat glioma cells with adenovirus-expressed mutant herpes simplex virus-thymidine kinase in combination with acyclovir. Cancer Gene Ther 7: 879-884, 2000
    • (2000) Cancer Gene Ther , vol.7 , pp. 879-884
    • Valerie, K.1    Brust, D.2    Farnsworth, J.3    Amir, C.4    Taher, M.M.5    Hershey, C.6    Feden, J.7
  • 31
    • 0035501206 scopus 로고    scopus 로고
    • Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells
    • Lammering G, Lin PS, Contessa JN, Hampton JL, Valerie K, Schmidt-Ullrich RK: Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells. Int J Radiat Oncol Biol Phys 51: 775-784, 2001
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 775-784
    • Lammering, G.1    Lin, P.S.2    Contessa, J.N.3    Hampton, J.L.4    Valerie, K.5    Schmidt-Ullrich, R.K.6
  • 33
    • 0024328428 scopus 로고
    • In vivo phosphorylation states and kinase activities of transforming p60c-src mutants
    • Jove R, Hanafusa T, Hamaguchi M, Hanafusa H: In vivo phosphorylation states and kinase activities of transforming p60c-src mutants. Oncogene Res 5: 49-60, 1989
    • (1989) Oncogene Res , vol.5 , pp. 49-60
    • Jove, R.1    Hanafusa, T.2    Hamaguchi, M.3    Hanafusa, H.4
  • 35
    • 0034282556 scopus 로고    scopus 로고
    • Extracellular domains drive homo- but not hetero-dimerization of erbB receptors
    • Ferguson KM, Darling PJ, Mohan MJ, Macatee TL, Lemmon MA: Extracellular domains drive homo- but not hetero-dimerization of erbB receptors. EMBO J 19: 4632-4643, 2000
    • (2000) EMBO J , vol.19 , pp. 4632-4643
    • Ferguson, K.M.1    Darling, P.J.2    Mohan, M.J.3    Macatee, T.L.4    Lemmon, M.A.5
  • 36
    • 0029814271 scopus 로고    scopus 로고
    • A hierarchical network of inter-receptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
    • Tzahar E, Waterman H, Chen X, Levkowitz G, Karunagaran D, Lavi S, Ratzkin BJ, Yarden Y: A hierarchical network of inter-receptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 16: 5276-5287, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 5276-5287
    • Tzahar, E.1    Waterman, H.2    Chen, X.3    Levkowitz, G.4    Karunagaran, D.5    Lavi, S.6    Ratzkin, B.J.7    Yarden, Y.8
  • 37
    • 0028077047 scopus 로고
    • Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product
    • Kim HH, Sierke SL, Koland JG: Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product. J Biol Chem 269: 24747-24755, 1994
    • (1994) J Biol Chem , vol.269 , pp. 24747-24755
    • Kim, H.H.1    Sierke, S.L.2    Koland, J.G.3
  • 38
  • 39
  • 40
    • 0031782321 scopus 로고    scopus 로고
    • Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation
    • Walker F, Kato A, Gonez LJ, Hibbs ML, Pouliot N, Levitzki A, Burgess AW: Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation. Mol Cell Biol 18: 7192-7204, 1998
    • (1998) Mol Cell Biol , vol.18 , pp. 7192-7204
    • Walker, F.1    Kato, A.2    Gonez, L.J.3    Hibbs, M.L.4    Pouliot, N.5    Levitzki, A.6    Burgess, A.W.7
  • 41
    • 0029067672 scopus 로고
    • An incomplete program of cellular tyrosine phosphorylations induced by kinase-defective epidermal growth factor receptors
    • Wright JD, Reuter CW, Weber MJ: An incomplete program of cellular tyrosine phosphorylations induced by kinase-defective epidermal growth factor receptors. J Biol Chem 270: 12085-12093, 1995
    • (1995) J Biol Chem , vol.270 , pp. 12085-12093
    • Wright, J.D.1    Reuter, C.W.2    Weber, M.J.3
  • 42
    • 0034693806 scopus 로고    scopus 로고
    • Selected glimpses into the activation and function of Src kinase
    • Bjorge JD, Jakymiw A, Fujita DJ: Selected glimpses into the activation and function of Src kinase. Oncogene 19: 5620-5635, 2000
    • (2000) Oncogene , vol.19 , pp. 5620-5635
    • Bjorge, J.D.1    Jakymiw, A.2    Fujita, D.J.3
  • 43
    • 0035374609 scopus 로고    scopus 로고
    • The Hunting of the SrcNature
    • Martin SG: The Hunting of the SrcNature. Rev Mol Cell Biol 2: 467-475, 2001
    • (2001) Rev Mol Cell Biol , vol.2 , pp. 467-475
    • Martin, S.G.1
  • 44
    • 0035394833 scopus 로고    scopus 로고
    • Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
    • Viloria-Petit A, Crombet T, Jothy S, Hicklin D, Bohlen P, Schlaeppi JM, Rak J, Kerbel RS: Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis. Cancer Res 61: 5090-5101, 2001
    • (2001) Cancer Res , vol.61 , pp. 5090-5101
    • Viloria-Petit, A.1    Crombet, T.2    Jothy, S.3    Hicklin, D.4    Bohlen, P.5    Schlaeppi, J.M.6    Rak, J.7    Kerbel, R.S.8
  • 45
    • 0036141447 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
    • Chakravarti A, Loeffler JS, Dyson NJ: Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res 62: 200-207, 2002
    • (2002) Cancer Res , vol.62 , pp. 200-207
    • Chakravarti, A.1    Loeffler, J.S.2    Dyson, N.J.3
  • 46
    • 0031730476 scopus 로고    scopus 로고
    • Expression of c-erbB3 protein in primary breast carcinomas
    • Naidu R, Yadav M, Nair S, Kutty MK: Expression of c-erbB3 protein in primary breast carcinomas. Br J Cancer 78: 1385-1390, 1998
    • (1998) Br J Cancer , vol.78 , pp. 1385-1390
    • Naidu, R.1    Yadav, M.2    Nair, S.3    Kutty, M.K.4
  • 47
    • 0031406620 scopus 로고    scopus 로고
    • c-erbB-3 protein expression in ductal carcinoma in situ of the breast
    • Bobrow LG, Millis RR, Happerfield LC, Gullick WJ: c-erbB-3 protein expression in ductal carcinoma in situ of the breast. Eur J Cancer 33: 1846-1850, 1997
    • (1997) Eur J Cancer , vol.33 , pp. 1846-1850
    • Bobrow, L.G.1    Millis, R.R.2    Happerfield, L.C.3    Gullick, W.J.4


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