Spinal CCL2 and microglial activation are involved in paclitaxel-evoked cold hyperalgesia

Brain Research Bulletin

Volumn 95, Issue , 2013, Pages 21-27

  Pevida, Marta ^a   Lastra, Ana ^a   Hidalgo, Agustín ^a   Baamonde, Ana ^a   Menéndez, Luis ^a  

^a UNIVERSIDAD DE OVIEDO   (Spain)

Author keywords

CCL2; Cold hyperalgesia; Microglia; Minocycline; Paclitaxel; Spinal cord

Indexed keywords

CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2 ANTAGONIST; GLIAL FIBRILLARY ACIDIC PROTEIN; J1 13863; MINOCYCLINE; MONOCYTE CHEMOTACTIC PROTEIN 1; PACLITAXEL; RS 504393; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY LABELING; ARTICLE; COLD HYPERALGESIA; COLD SENSITIVITY; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; LUMBAR SPINAL CORD; MACROGLIA; MALE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSORY NEUROPATHY;

ANIMALS; CHEMOKINE CCL2; COLD TEMPERATURE; HYPERALGESIA; MALE; MICE; MICROGLIA; MINOCYCLINE; NEURALGIA; PACLITAXEL; RECEPTORS, CCR2; SPINAL CORD;

EID: 84876701595     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2013.03.005     Document Type: Article

References (43)

1. Abbadie C., Lindia J.A., Cumiskey A.M., Peterson L.B., Mudgett J.S., Bayne E.K., DeMartino J.A., MacIntyre D.E., Forrest M.J. Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2. Proceedings of the National Academy of Sciences of the United States of America 2003, 100:7947-7952.
2. Argyriou A.A., Koltzenburg M., Polychronopoulos P., Papapetropoulos S., Kalofonos H.P. Peripheral nerve damage associated with administration of taxanes in patients with cancer. Critical Reviews in Oncology/Hematology 2008, 66:218-228.
3. Baamonde A., Hidalgo A., Menéndez L. Involvement of glutamate NMDA and AMPA receptors, glial cells and IL-1β in the spinal hyperalgesia evoked by the chemokine CCL2 in mice. Neuroscience Letters 2011, 502:178-181.
4. Babcock A.A., Kuziel W.A., Rivest S., Owens T. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. Journal of Neuroscience 2003, 23:7922-7930.
5. Burgos E., Gómez-Nicola D., Pascual D., Martín M.I., Nieto-Sampedro M., Goicoechea C. Cannabinoid agonist WIN 55 212-2 prevents the development of paclitaxel-induced peripheral neuropathy in rats. Possible involvement of spinal glial cells. European Journal of Pain 2012, 682:62-72.
6. Calvo M., Bennett D.L. The mechanisms of microgliosis and pain following peripheral nerve injury. Experimental Neurology 2012, 234:271-282.
7. Cata J.P., Weng H.R., Dougherty P.M. The effects of thalidomide and minocycline on taxol-induced hyperalgesia in rats. Brain Research 2008, 1229:100-110.
8. De Brabander M., Geuens G., Nuydens R., Willebrords R., De Mey J. Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores. Proceedings of the National Academy of Sciences of the United States of America 1981, 78:5608-5612.
9. Dougherty P.M., Cata J.P., Cordella J.V., Burton A., Weng H.R. Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients. Pain 2004, 109:132-142.
10. Gao Y.J., Ji R.R. Chemokines, neuronal-glial interactions, and central processing of neuropathic pain. Pharmacology and Therapeutics 2010, 126:56-68.
11. Gao Y.J., Zhang L., Ji R.R. Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1. Glia 2010, 58:1871-1880.
12. Gao Y.J., Zhang L., Samad O.A., Suter M.R., Yasuhiko K., Xu Z.Z., Park J.Y., Lind A.L., Ma Q., Ji R.R. JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. Journal of Neuroscience 2009, 29:4096-4108.
13. Ghoreishi Z., Esfahani A., Djazayeri A., Djalali M., Golestan B., Ayromlou H., Hashemzade S., Asghari Jafarabadi M., Montazeri V., Keshavarz S.A., Darabi M. Omega-3 fatty acids are protective against paclitaxel-induced peripheral neuropathy: a randomized double-blind placebo controlled trial. BMC Cancer 2012, 12:355.
14. Glantz M.J., Choy H., Kearns C.M., Mills P.C., Wahlberg L.U., Zuhowski E.G., Calabresi P., Egorin M.J. Paclitaxel disposition in plasma and central nervous systems of humans and rats with brain tumors. Journal of the National Cancer Institute 1995, 87:1077-1081.
15. Hidaka T., Shima T., Nagira K., Ieki M., Nakamura T., Aono Y., Kuraishi Y., Arai T., Saito S. Herbal medicine Shakuyaku-kanzo-to reduces paclitaxel-induced painful peripheral neuropathy in mice. European Journal of Pain 2009, 13:22-27.
16. Hinojosa A.E., García-Bueno B., Leza J.C., Madrigal J.L. Regulation of CCL2/MCP-1 production in astrocytes by desipramine and atomoxetine: involvement of alpha2 adrenergic receptors. Brain Research Bulletin 2011, 86:326-333.
17. Jaggi A.S., Singh N. Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy. Toxicology 2012, 291:1-9.
18. Jeon S.M., Lee K.M., Cho H.J. Expression of monocyte chemoattractant protein-1 in rat dorsal root ganglia and spinal cord in experimental models of neuropathic pain. Brain Research 2009, 1251:103-111.
19. Kiguchi N., Kobayashi Y., Maeda T., Saika F., Kishioka S. CC-chemokine MIP-1 in the spinal cord contributes to nerve injury-induced neuropathic pain. Neuroscience Letters 2010, 484:17-21.
20. Kiguchi N., Kobayashi Y., Kishioka S. Chemokines and cytokines in neuroinflammation leading to neuropathic pain. Current Opinion in Pharmacology 2012, 12:55-61.
21. Le X.F., Bast R.C. Src family kinases and paclitaxel sensitivity. Cancer Biology and Therapy 2011, 12:260-299.
22. Liu C.C., Lu N., Cui Y., Yang T., Zhao Z.Q., Xin W.J., Liu X.G. Prevention of paclitaxel-induced allodynia by minocycline: effect on loss of peripheral nerve fibers and infiltration of macrophages in rats. Molecular Pain 2010, 6:76.
23. Menéndez L., Lastra A., Hidalgo A., Baamonde A. Unilateral hot plate test: a simple and sensitive method for detecting central and peripheral hyperalgesia in mice. Journal of Neuroscience Methods 2002, 113:91-97.
24. Mirzadegan T., Diehl F., Ebi B., Bhakta S., Polsky I., McCarley D., Mulkins M., Weatherhead G.S., Lapierre J.M., Dankwardt J., Morgans D., Wilhelm R., Jarnagin K. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle. Journal of Biological Chemistry 2000, 275:25562-25571.
25. Naguib M., Xu J.J., Diaz P., Brown D.L., Cogdell D., Bie B., Hu J., Craig S., Hittelman W.N. Prevention of paclitaxel-induced neuropathy through activation of the central cannabinoid type 2 receptor system anesthesia-analgesia. Anesthesia and Analgesia 2012, 114:1104-1120.
26. Narita M., Yoshida T., Nakajima M., Narita M., Miyatake M., Takagi T., Yajima Y., Suzuki T. Direct evidence for spinal cord microglia in the development of a neuropathic pain-like state in mice. Journal of Neurochemistry 2006, 275:25562-255671.
27. Old E.A., Malcangio M. Chemokine mediated neuron-glia communication and aberrant signalling in neuropathic pain states. Current Opinion in Pharmacology 2012, 12:67-73.
28. Peters C.M., Jimenez-Andrade J.M., Jonas B.M., Sevcik M.A., Koewler N.J., Ghilardi J.R., Wong G.Y., Mantyh P.W. Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells. Experimental Neurology 2007, 203:42-54.
29. Quasthoff S., Hartung H.P. Chemotherapy-induced peripheral neuropathy. Journal of Neurology 2002, 249:9-17.
30. Ransohoff R.M., Liu L., Cardona A.E. Chemokines and chemokine receptors: multipurpose players in neuroinflammation. International Review of Neurobiology 2007, 82:187-204.
31. Rowinsky E.K., Donehower R.C., Jones R.J., Tucker R.W. Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol. Cancer Research 1988, 48:4093-4100.
32. Schomberg D., Olson J.K. Immune responses of microglia in the spinal cord: contribution to pain states. Experimental Neurology 2012, 234:262-270.
33. Thacker M.A., Clark A.K., Bishop T., Grist J., Yip P.K., Moon L.D., Thompson S.W., Marchand F., McMahon S.B. CCL2 is a key mediator of microglia activation in neuropathic pain states. European Journal of Pain 2009, 13:263-272.
34. Van Steenwinckel J., Reaux-Le Goazigo A., Pommier B., Mauborgne A., Dansereau M.-A., Kitabgi P., Sarret P., Pohl M., Melik-Parsadaniantz S. CCL2 released from neuronal synaptic vesicles in the spinal cord is a major mediator of local inflammation and pain after peripheral nerve injury. Journal of Neuroscience 2011, 31:5865-5875.
35. Wang X.M., Lehky T.J., Brell J.M., Dorsey S.G. Discovering cytokines as targets for chemotherapy-induced painful peripheral neuropathy. Cytokine 2012, 59:3-9.
36. Watkins L.R., Hutchinson M.R., Ledeboer A., Wieseler-Frank J., Milligan E.D., Maier S.F. Glia as the "bad guys": implications for improving clinical pain control and the clinical utility of opioids. Brain, Behavior, and Immunity 2007, 207:131-146.
37. White F.A., Sun J., Waters S.M., Ma C., Ren D., Ripsch M., Steflik J., Cortright D.N., Lamotte R.H., Miller R.J. Excitatory monocyte chemoattractant protein-1 signaling is up-regulated in sensory neurons after chronic compression of the dorsal root ganglion. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:14092-14097.
38. White F.A., Feldman P., Miller R.J. Chemokine signaling and the management of neuropathic pain. Molecular Interventions 2009, 9:188-195.
39. Wolf S., Barton D., Kottschade L., Grothey A., Loprinzi C. Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies. European Journal of Cancer 2008, 44:1507-1515.
40. Zhang J., Shi X.Q., Echeverry S., Mogil J.S., De Koninck Y., Rivest S. Expression of CCR2 in both resident and bone marrow derived microglia plays a critical role in neuropathic pain. Journal of Neuroscience 2007, 27:12396-12406.
41. Zhang H., Yoon S.-Y., Zhang H., Dougherty P.M. Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of paclitaxel-induced painful neuropathy. Journal of Pain 2012, 13:293-303.
42. Zhang Z.J., Dong Y.L., Lu Y., Cao S., Zhao Z.Q., Gao Y.J., Chemokine CCL2 and its receptor CCR2 in the medullary dorsal horn are involved in trigeminal neuropathic pain. Journal of Neuroinflammation 2012, 9:136.
43. Zheng F.Y., Xiao W.H., Bennett G.J. The response of spinal microglia to chemotherapy evoked painful peripheral neuropathies is distinct from that evoked by traumatic nerve injuries. Neuroscience 2011, 176:447-454.