-
1
-
-
0023677290
-
Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples
-
1:STN:280:DyaL1c3mvFKntw%3D%3D 10.2307/2531856 3390507
-
AJ Bailer CJ Portier 1988 Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples Biometrics 44 417 431 1:STN:280:DyaL1c3mvFKntw%3D%3D 10.2307/2531856 3390507
-
(1988)
Biometrics
, vol.44
, pp. 417-431
-
-
Bailer, A.J.1
Portier, C.J.2
-
2
-
-
40849116178
-
Subchronic toxicity study of 3-monochloropropane-1, 2-diol administered by drinking water to B6C3F1 mice
-
1:CAS:528:DC%2BD1cXjs1Khsrs%3D 10.1016/j.fct.2007.12.030 18328611
-
WS Cho BS Han H Lee C Kim KT Nam K Park M Choi SJ Kim SH Kim J Jeong DD Jang 2008 Subchronic toxicity study of 3-monochloropropane-1, 2-diol administered by drinking water to B6C3F1 mice Food Chem Toxicol 46 1666 1673 1:CAS:528:DC%2BD1cXjs1Khsrs%3D 10.1016/j.fct.2007.12.030 18328611
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 1666-1673
-
-
Cho, W.S.1
Han, B.S.2
Lee, H.3
Kim, C.4
Nam, K.T.5
Park, K.6
Choi, M.7
Kim, S.J.8
Kim, S.H.9
Jeong, J.10
Jang, D.D.11
-
3
-
-
50249083881
-
Carcinogenicity study of 3-monochloropropane-1, 2-diol in Sprague-Dawley rats
-
1:CAS:528:DC%2BD1cXhtVKnsbbK 10.1016/j.fct.2008.07.003 18680782
-
WS Cho BS Han KT Nam K Park M Choi SH Kim J Jeong DD Jang 2008 Carcinogenicity study of 3-monochloropropane-1, 2-diol in Sprague-Dawley rats Food Chem Toxicol 46 3172 3177 1:CAS:528:DC%2BD1cXhtVKnsbbK 10.1016/j.fct.2008. 07.003 18680782
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 3172-3177
-
-
Cho, W.S.1
Han, B.S.2
Nam, K.T.3
Park, K.4
Choi, M.5
Kim, S.H.6
Jeong, J.7
Jang, D.D.8
-
4
-
-
0000336139
-
Regression models and life-tables
-
DR Cox 1972 Regression models and life-tables J Royal Stat Soc B34 187 220
-
(1972)
J Royal Stat Soc
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
5
-
-
0009663357
-
A multiple comparison procedure for comparing several treatments with a control
-
10.2307/2281208
-
CW Dunnett 1955 A multiple comparison procedure for comparing several treatments with a control J Am Stat Assoc 50 1096 1121 10.2307/2281208
-
(1955)
J Am Stat Assoc
, vol.50
, pp. 1096-1121
-
-
Dunnett, C.W.1
-
6
-
-
33751358979
-
Evaluation of the genotoxic potential of 3-monochloropropane-1,2-diol (3-MCPD) and its metabolites, glycidol and β-chlorolactic acid, using the single cell gel/comet assay
-
DOI 10.1016/j.fct.2006.07.014, PII S0278691506002018
-
R El Ramy M Ould Elhkim S Lezmi JM Poul 2007 Evaluation of the genotoxic potential of 3-monochloropropane-1, 2-diol (3-MCPD) and its metabolites, glycidol and beta-chlorolactic acid, using the single cell gel/comet assay Food Chem Toxicol 45 41 48 1:CAS:528:DC%2BD28Xht1ChsrfP 10.1016/j.fct.2006.07.014 16971032 (Pubitemid 44810906)
-
(2007)
Food and Chemical Toxicology
, vol.45
, Issue.1
, pp. 41-48
-
-
El Ramy, R.1
Ould Elhkim, M.2
Lezmi, S.3
Poul, J.M.4
-
8
-
-
0019256193
-
Effects of low doses of alpha-chlorohydrin on phosphatases, beta-glucosidase, beta-glucuronidase & hyaluronidase of rat testis & epididymis
-
1:CAS:528:DyaL3MXktFCgsQ%3D%3D 6260636
-
SK Gill SS Guraya 1980 Effects of low doses of alpha-chlorohydrin on phosphatases, beta-glucosidase, beta-glucuronidase & hyaluronidase of rat testis & epididymis Indian J Exp Biol 18 1351 1352 1:CAS:528: DyaL3MXktFCgsQ%3D%3D 6260636
-
(1980)
Indian J Exp Biol
, vol.18
, pp. 1351-1352
-
-
Gill, S.K.1
Guraya, S.S.2
-
9
-
-
6844241272
-
-
Unpublished report No. ULR 130 ABC/861423 from Huntingdon Research Center Ltd., Huntingdon, Cambridgeshire, United Kingdom
-
Henderson L, Bosworth H, Ransome S, Banks S, Brabbs C, Tinner A (1987) An assessment of the mutagenic potential of 1,3-dichloro-2-propanol, 3-chloro-1,2-propanediol and a cocktail of chloropropanols using the mouse lymphoma TK locus assay. Unpublished report No. ULR 130 ABC/861423 from Huntingdon Research Center Ltd., Huntingdon, Cambridgeshire, United Kingdom
-
(1987)
An Assessment of the Mutagenic Potential of 1,3-dichloro-2-propanol, 3-chloro-1,2-propanediol and A Cocktail of Chloropropanols Using the Mouse Lymphoma TK Locus Assay
-
-
Henderson, L.1
Bosworth, H.2
Ransome, S.3
Banks, S.4
Brabbs, C.5
Tinner, A.6
-
10
-
-
21644460384
-
-
ICH Guidance for Industry S1C U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Biologics Evaluation and Research (CBER). Revision 1
-
ICH Guidance for Industry S1C (2008) Guidance for Industry S1C(R2) Dose Selection for Carcinogenicity Studies. U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Biologics Evaluation and Research (CBER). Revision 1
-
(2008)
Guidance for Industry S1C(R2) Dose Selection for Carcinogenicity Studies
-
-
-
11
-
-
0020876229
-
Antifertility actions of alpha-chlorohydrin in the male
-
1:CAS:528:DyaL3sXlsFahsr8%3D 6362633
-
AR Jones 1983 Antifertility actions of alpha-chlorohydrin in the male Aust J Biol Sci 36 333 350 1:CAS:528:DyaL3sXlsFahsr8%3D 6362633
-
(1983)
Aust J Biol Sci
, vol.36
, pp. 333-350
-
-
Jones, A.R.1
-
12
-
-
0024948071
-
Oxidative metabolic activity of boar spermatozoa: A system for assessing anti-glycolytic activity of potential inhibitors in vitro
-
1:CAS:528:DyaK38Xlt1Ckurc%3D 10.1071/RD9890357 2517668
-
AR Jones LA Chantrill 1989 Oxidative metabolic activity of boar spermatozoa: a system for assessing anti-glycolytic activity of potential inhibitors in vitro Reprod Fertil Dev 1 357 367 1:CAS:528:DyaK38Xlt1Ckurc%3D 10.1071/RD9890357 2517668
-
(1989)
Reprod Fertil Dev
, vol.1
, pp. 357-367
-
-
Jones, A.R.1
Chantrill, L.A.2
-
13
-
-
0019483282
-
The fate of oxalic acid in the Wistar rat
-
1:CAS:528:DyaL38Xjt1Wkug%3D%3D 10.3109/00498258109045849 7293229
-
AR Jones P Gadiel D Stevenson 1981 The fate of oxalic acid in the Wistar rat Xenobiotica 11 385 390 1:CAS:528:DyaL38Xjt1Wkug%3D%3D 10.3109/ 00498258109045849 7293229
-
(1981)
Xenobiotica
, vol.11
, pp. 385-390
-
-
Jones, A.R.1
Gadiel, P.2
Stevenson, D.3
-
14
-
-
0017331537
-
In vivo & in vitro alkylation of testicular cysteine by alpha-chlorohydrin
-
1:CAS:528:DyaE2sXhs1Gksbg%3D 914328
-
NR Kalla MP Bansal 1977 In vivo & in vitro alkylation of testicular cysteine by alpha-chlorohydrin Indian J Exp Biol 15 232 233 1:CAS:528: DyaE2sXhs1Gksbg%3D 914328
-
(1977)
Indian J Exp Biol
, vol.15
, pp. 232-233
-
-
Kalla, N.R.1
Bansal, M.P.2
-
15
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
10.2307/2281868
-
EL Kaplan P Meier 1958 Nonparametric estimation from incomplete observations J Am Stat Assoc 53 457 481 10.2307/2281868
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
16
-
-
8444220087
-
Mechanism of antifertility in male rats treated with 3-monochloro-1,2- propanediol (3-MCPD)
-
DOI 10.1080/15287390490514651
-
SJ Kwack SS Kim YW Choi GS Rhee R Lee JH Seok SY Chae YH Won KJ Lim KS Choi KL Park BM Lee 2004 Mechanism of antifertility in male rats treated with 3-monochloro-1, 2-propanediol (3-MCPD) J Toxicol Environ Health A 67 2001 2011 1:CAS:528:DC%2BD2cXoslGhsLk%3D 10.1080/15287390490514651 15513898 (Pubitemid 39488869)
-
(2004)
Journal of Toxicology and Environmental Health - Part A
, vol.67
, Issue.23-24
, pp. 2001-2011
-
-
Seung, J.K.1
Soon, S.K.2
Yo, W.C.3
Gyu, S.R.4
Rhee, D.L.5
Ji, H.S.6
Soo, Y.C.7
Yong, H.W.8
Kwon, J.L.9
Kwang, S.C.10
Kui, L.P.11
Byung, M.L.12
-
17
-
-
0018635422
-
Antifertility activity of alpha-chlorohydrin (3-chloro-1, 2 propanediol, U-5897) on the female rats
-
1:CAS:528:DyaL3MXltVyqurY%3D 545975
-
NK Lohika M Arya 1979 Antifertility activity of alpha-chlorohydrin (3-chloro-1, 2 propanediol, U-5897) on the female rats Acta Eur Fertil 10 23 27 1:CAS:528:DyaL3MXltVyqurY%3D 545975
-
(1979)
Acta Eur Fertil
, vol.10
, pp. 23-27
-
-
Lohika, N.K.1
Arya, M.2
-
18
-
-
0031907147
-
Carcinogenicity of monochloro-1, 2-propanediol (alpha-chlorohydrin, 3-MCPD)
-
1:CAS:528:DyaK1cXnvVSgsw%3D%3D
-
BS Lynch DW Bryant GJ Hook ER Nestmann IC Munro 1998 Carcinogenicity of monochloro-1, 2-propanediol (alpha-chlorohydrin, 3-MCPD) Int J Toxicol 17 47 76 1:CAS:528:DyaK1cXnvVSgsw%3D%3D
-
(1998)
Int J Toxicol
, vol.17
, pp. 47-76
-
-
Lynch, B.S.1
Bryant, D.W.2
Hook, G.J.3
Nestmann, E.R.4
Munro, I.C.5
-
19
-
-
0033638808
-
3-monochloropropane-1, 2-diol (3-MCPD) in soy sauces and similar products available from retail outlets in the UK
-
1:CAS:528:DC%2BD3cXptV2mur0%3D 10.1080/026520300750038072 11271703
-
R Macarthur C Crews A Davies P Brereton P Hough D Harvey 2000 3-monochloropropane-1, 2-diol (3-MCPD) in soy sauces and similar products available from retail outlets in the UK Food Addit Contam 17 903 906 1:CAS:528:DC%2BD3cXptV2mur0%3D 10.1080/026520300750038072 11271703
-
(2000)
Food Addit Contam
, vol.17
, pp. 903-906
-
-
MacArthur, R.1
Crews, C.2
Davies, A.3
Brereton, P.4
Hough, P.5
Harvey, D.6
-
22
-
-
0024292607
-
Determination of residual epichlorohydrin and 3-chloropropanediol in water by gas chromatography with electron-capture detection
-
1:CAS:528:DyaL1cXksFegs74%3D 10.1016/S0021-9673(01)83859-0 3403653
-
RL Pesselman MJ Feit 1988 Determination of residual epichlorohydrin and 3-chloropropanediol in water by gas chromatography with electron-capture detection J Chromatogr 439 448 452 1:CAS:528:DyaL1cXksFegs74%3D 10.1016/S0021-9673(01)83859-0 3403653
-
(1988)
J Chromatogr
, vol.439
, pp. 448-452
-
-
Pesselman, R.L.1
Feit, M.J.2
-
23
-
-
0042880882
-
In vivo genotoxicity studies with 3-monochloropropan-1,2-diol
-
DOI 10.1093/mutage/geg017
-
S Robjohns R Marshall M Fellows G Kowalczyk 2003 In vivo genotoxicity studies with 3-monochloropropan-1, 2-diol Mutagenesis 18 401 404 1:CAS:528:DC%2BD3sXnt1Kisr0%3D 10.1093/mutage/geg017 12960406 (Pubitemid 37098969)
-
(2003)
Mutagenesis
, vol.18
, Issue.5
, pp. 401-404
-
-
Robjohns, S.1
Marshall, R.2
Fellows, M.3
Kowalczyk, G.4
-
24
-
-
0020556324
-
Genotoxicity, metabolism and blood kinetics of epichlorohydrin in mice
-
1:CAS:528:DyaL3sXltVSkt7w%3D 10.1016/0165-1218(83)90144-1 6877269
-
AM Rossi L Migliore D Lascialfari I Sbrana N Loprieno M Tortoreto F Bidoli C Pantarotto 1983 Genotoxicity, metabolism and blood kinetics of epichlorohydrin in mice Mutat Res 118 213 226 1:CAS:528:DyaL3sXltVSkt7w%3D 10.1016/0165-1218(83)90144-1 6877269
-
(1983)
Mutat Res
, vol.118
, pp. 213-226
-
-
Rossi, A.M.1
Migliore, L.2
Lascialfari, D.3
Sbrana, I.4
Loprieno, N.5
Tortoreto, M.6
Bidoli, F.7
Pantarotto, C.8
-
25
-
-
21044454251
-
-
Scientific Committee on Food Adopted on 30 May 2001, SCF/CS/CNTM/OTH/17 Final
-
Scientific Committee on Food (2001) Opinion on 3-monochloro-propane-1,2- diol (3-MCPD). Adopted on 30 May 2001, SCF/CS/CNTM/OTH/17 Final
-
(2001)
Opinion on 3-monochloro-propane-1,2-diol (3-MCPD)
-
-
-
26
-
-
0009847108
-
Carcinogenicity study on 3-monochloropropane 1,2-diol (3-MCPD) administered in drinking water to Fischer 344 rats
-
Nestec Ltd., Research and Development, Switzerland
-
Sunahara G, Perrin I, Marchessini M (1993) Carcinogenicity study on 3-monochloropropane 1,2-diol (3-MCPD) administered in drinking water to Fischer 344 rats. Report No. RE-SR93003, Nestec Ltd., Research and Development, Switzerland
-
(1993)
Report No. RE-SR93003
-
-
Sunahara, G.1
Perrin, I.2
Marchessini, M.3
-
27
-
-
0016759979
-
Tests for trend in life table analysis
-
10.1093/biomet/62.3.679
-
RE Tarone 1975 Tests for trend in life table analysis Biometrika 62 679 690 10.1093/biomet/62.3.679
-
(1975)
Biometrika
, vol.62
, pp. 679-690
-
-
Tarone, R.E.1
-
29
-
-
0019495095
-
Carcinogenicity tests of certain environmental and industrial chemicals
-
1:CAS:528:DyaL3MXls1emt7Y%3D 6942197
-
EK Weisburger BM Ulland J Nam JJ Gart JH Weisburger 1981 Carcinogenicity tests of certain environmental and industrial chemicals J Natl Cancer Inst 67 75 88 1:CAS:528:DyaL3MXls1emt7Y%3D 6942197
-
(1981)
J Natl Cancer Inst
, vol.67
, pp. 75-88
-
-
Weisburger, E.K.1
Ulland, B.M.2
Nam, J.3
Gart, J.J.4
Weisburger, J.H.5
-
30
-
-
0015025451
-
A test for differences between treatment means when several dose levels are compared with a zero dose control
-
1:STN:280:DyaE3M7jtlOltA%3D%3D 10.2307/2528930 5547548
-
DA Williams 1971 A test for differences between treatment means when several dose levels are compared with a zero dose control Biometrics 27 103 117 1:STN:280:DyaE3M7jtlOltA%3D%3D 10.2307/2528930 5547548
-
(1971)
Biometrics
, vol.27
, pp. 103-117
-
-
Williams, D.A.1
|