Lipopolysaccharide-induced failure of the gut barrier is site-specific and inhibitable by growth hormone

Inflammation Research

Volumn 62, Issue 4, 2013, Pages 407-415

  Yue, Chao ^a   Wang, Wei ^a   Tian, Wei Liang ^a   Huang, Qian ^a   Zhao, Ri Sheng ^a   Zhao, Yun Zhao ^a   Li, Qiu Rong ^a   Li, Jie Shou ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Endotoxemia; Growth hormone; Gut barrier failure; Lipopolysaccharide; Survival

Indexed keywords

GREEN FLUORESCENT PROTEIN; LIPOPOLYSACCHARIDE; RECOMBINANT GROWTH HORMONE;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG RESPONSE; ENDOTOXEMIA; ENTEROSTOMY TUBE; ESCHERICHIA COLI; HISTOPATHOLOGY; ILEUM; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA PERMEABILITY; MALE; MESENTERY LYMPH NODE; MORTALITY; NONHUMAN; RAT; SURVIVAL;

ANIMALS; APOPTOSIS; BACTERIAL TRANSLOCATION; ENDOTOXEMIA; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; HUMAN GROWTH HORMONE; INTESTINES; LIPOPOLYSACCHARIDES; LYMPH NODES; MALE; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS;

EID: 84876677362     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-013-0593-4     Document Type: Article

References (41)

1. Zhang L, Jin S, Wang C, et al. Histone deacetylase inhibitors attenuate acute lung injury during cecal ligation and puncture-induced polymicrobial sepsis. World J Surg. 2010;34(7):1676-83.
2. Balzan S, de Almeida Quadros C, de Cleva R, et al. Bacterial translocation: overview of mechanisms and clinical impact. J Gastroenterol Hepatol. 2007;22(4):464-71. (Pubitemid 46435001)
3. Garrett RE, Bar-Or D. Constipation critical illness and mortality. Gut-derived toxidromes - real and now imagined. Crit Care Med. 2008;36(9):2710-1.
4. Zhang W, Gu Y, Chen Y, et al. Intestinal flora imbalance results in altered bacterial translocation and liver function in rats with experimental cirrhosis. Eur J Gastroenterol Hepatol. 2010;22(12):1481-6.
5. Song J, Wolf SE, Herndon DN, et al. Second hit post burn increased proximal gut mucosa epithelial cells damage. Shock. 2008;30(2):184-8.
6. Yang R, Miki K, Oksala N, et al. Bile high-mobility group box 1 contributes to gut barrier dysfunction in experimental endotoxemia. Am J Physiol Regul Integr Comp Physiol. 2009;297(2):R362-9.
7. Enomoto N, Takei Y, Yamashina S. Burn injury sensitizes rat Kupffer cells via mechanisms dependent on gut-derived endotoxin. J Gastroenterol. 2004;39(12):1175-81. (Pubitemid 40074284)
8. Crouser ED, Julian MW, Weinstein DM, et al. Endotoxin-induced ileal Mucosal Injury and Nitric Oxide Dysregulation Are Temporally Dissociated. Am J Respir Crit Care Med. 2000;161(5):1705-12. (Pubitemid 30329051)
9. Duska F, Fric M, Waldauf P, et al. Frequent intravenous pulses of growth hormone together with glutamine supplementation in prolonged critical illness after multiple trauma: effects on nitrogen balance, insulin resistance, and substrate oxidation. Crit Care Med. 2008;36(6):1707-13.
10. Branski LK, Herndon DN, Barrow RE, et al. Randomized controlled trial to determine the efficacy of long-term growth hormone treatment in severely burned children. Ann Surg. 2009;250(4):514-23.
11. Gomez-de-Segura IA, Prieto I, Grande AG, et al. Growth hormone reduces mortality and bacterial translocation in irradiated rats. Acta Oncol. 1998;37(2):179-85. (Pubitemid 28255190)
12. Vazquez I, Gomez-de-Segura IA, Grande AG, et al. Protective effect of enriched diet plus growth hormone administration on radiation-induced intestinal injury and on its evolutionary pattern in the rat. Dig Dis Sci. 1999;44(11):2350-8.
13. Eizaguirre I, Aldazabal P, Barrena MJ, et al. Effect of growth hormone on bacterial translocation in experimental short-bowel syndrome. Pediatr Surg Int. 1999;15(3-4):160-3. (Pubitemid 29257690)
14. Samel Stephan, Keese Michael, Kleczka Martha. Microscopy of bacterial translocation during small bowel obstruction and ischemia in vivo-a new animal model. BMC Surg. 2002;2:6.
15. Wilson TH, Wiseman G. The use of sacsof everted small intestine for the study of the transference of substances from the mucosal to serosal surface. J Physiol. 1954;123(1):116-25.
16. Tawadrous Z, Delude RL, Fink MP. Resuscitation from hemorrhagic shock with Ringer's ethyl pyruvate solution improves survival and ameliorates intestinal mucosal hyperpermeability in rats. Shock. 2002;17(6):473-7.
17. Chiu CJ, McArdle AH, Brown RA, et al. Intestinal mucosal lesion in low-flow states. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg. 1970;101(4):478-83.
18. Ouhtit A, Muller HK, Davis DW, et al. Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin. Am J Pathol. 2000;156(1):201-7. (Pubitemid 30644453)
19. Tascilar N, Irkorucu O, Tascilar O, et al. Bacterial translocation in experimental stroke: what happens to the gut barrier? Bratisl Lek Listy. 2010;111(4):194-9.
20. Velasco N. Gut barrier in the critically ill patient. Facts and trends. Rev Med Chil. 2006;134(8):1033-9.
21. Magnotti LJ, Deitch EA. Burns, bacterial translocation, gut barrier function and failure. Burn Care Rehabil. 2005;26(5):383-91. (Pubitemid 41433676)
22. Caine WR, Metzler-Zebeli BU, McFall M, et al. Supplementation of diets for gestating sows with zinc amino acid complex and gastric intubation of suckling pigs with zinc-methionine on mineral status, intestinal morphology and bacterial translocation in lipopolysaccharide-challenged early-weaned pigs. Res Vet Sci. 2009;86(3):453-62.
23. Deitch EA, Taylor M, Grisham M. Endotoxin induces bacterial translocation and increases xanthine oxidase activity. J Trauma. 1989;29(12):1679-83. (Pubitemid 20024878)
24. Mosenthal AC, Xu D, Deitch EA. Elemental and intravenous total parenteral nutrition diet-induced gut barrier failure is intestinal site specific and can be prevented by feeding nonfermentable fiber. Crit Care Med. 2002;30(2):396-402. (Pubitemid 34158126)
25. Fukushima R, Gianotti L, Alexander JW. The primary site of bacterial translocation. Arch Surg. 1994;129(1):53-8. (Pubitemid 24024518)
26. Powell DW. Barrier function of epithelia. Am J Physiol. 1981;241(4):G275-88.
27. Wiest R, Rath HC. Bacterial translocation in the gut. Best Pract Res Clin Gastroenterol. 2003;17(3):397-425.
28. Pritts TA, Moon MR, Wang Q, et al. Activation of NF-kappa B varies in different regions of the gastrointestinal tract during endotoxemia. Shock. 2000;14(2):118-22.
29. Parikh AA, Moon MR, Pritts TA, et al. IL-1α induction of NF-κB activation in human intestinal epithelial cells is independent of oxyradical signaling. Shock. 2000;13(1):8-13.
30. Uronen-Hansson H, Allen ML, Lichtarowicz-Krynska E, et al. Growth hormone enhances proinflammatory cytokine production by monocytes in whole blood. Growth Horm IGF Res. 2003;13(5):282-6. (Pubitemid 37161683)
31. Tripathi A, Sodhi A. Growth hormone-induced production of cytokines in murine peritoneal macrophages in vitro: role of JAK/STAT, P13K, PKC and MAP kinases. Immunobiology. 2009;214(6):430-40.
32. Kappel M, Hansen MB, Diamant M, et al. In vitro effects of human growth hormone on the proliferative responses and cytokine production of blood mononuclear cells. Horm Metab Res. 1994;26(12):612-4. (Pubitemid 24381124)
33. Elsasser TH, Fayer R, Rumsey TS, et al. Recombinant bovine somatotropin blunts plasma tumour necrosis factor-a, cortisol, and thromboxane-B2 responses to endotoxin in vivo. Endocrinology. 1994;134(3):1082-8. (Pubitemid 24085554)
34. Wang P, Li N, Li JS. The role of endotoxin, TNF-alpha and IL-6 in inducing the state of growth hormone insensitivity. World J Gastroenterol. 2002;8(3):531-6. (Pubitemid 34692758)
35. Liao W, Rudling M, Angelin B. Growth hormone potentiates the in vivo biological activities of endotoxin in the rat. Eur J Clin Invest. 1996;26(3):254-8. (Pubitemid 26083220)
36. Takala J, Ruokonen E, Webster NR. Increased mortality associated with growth hormone treatment in critically ill patients. N Engl J Med. 1999;341(11):785-92. (Pubitemid 29420473)
37. Jeschke MG, Finnerty CC, Kulp GA, et al. Combination of recombinant human growth hormone and propranolol decreases hypermetabolism and inflammation in severely burned children. Pediatr Crit Care Med. 2008;9(2):209-16. (Pubitemid 351355027)
38. Leaman DW, Leung S, Li X, et al. Regulation of STAT-dependent pathways by growth factors and cytokines. FASEB J. 1996;10(14):1578-88. (Pubitemid 27043774)
39. Gilpin DA, Hsieh CC, Kuninger DT, et al. Effect of thermal injury on the expression of transcription factors that regulate acutephase response genes: The response of C/EBP alpha, C/EBP beta, and C/EBP delta to thermal injury. Surgery. 1996;119(6):674-83. (Pubitemid 26184424)
40. Haeffner A, Thieblemont N, Deas O, et al. Inhibitory effect of growth hormone on TNF-alpha secretion and nuclear factor-kappaB translocation in lipopolysaccharide-stimulated human monocytes. J Immunol. 1997;158(3):1310-4. (Pubitemid 127469956)
41. Dejkhamron P, Thimmarayappa J, Kotlyarevska K, et al. Lipopolysaccharide (LPS) directly suppresses growth hormone receptor (GHR) expression through MyD88-dependent and-independent Toll-like receptor-4/MD2 complex signaling pathways. Mol Cell Endocrinol. 2007;274(1-2):35-42. (Pubitemid 47126683)