Supplementation of diets for gestating sows with zinc amino acid complex and gastric intubation of suckling pigs with zinc-methionine on mineral status, intestinal morphology and bacterial translocation in lipopolysaccharide-challenged early-weaned pigs

Research in Veterinary Science

Volumn 86, Issue 3, 2009, Pages 453-462

  Caine, W R ^a   Metzler Zebeli, B U ^b   McFall, M ^a   Miller, B ^a   Ward, T L ^c   Kirkwood, R N ^d   Mosenthin, R ^b  

^a ALBERTA AGRICULTURE AND RURAL DEVELOPMENT   (Canada)

^b UNIVERSITY OF HOHENHEIM   (Germany)

^c ZINPRO CORPORATION   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Bacterial translocation; Intestinal morphology; Lipopolysaccharide; Pigs; Zinc

Indexed keywords

AMINO ACID; COPPER; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IRON; METHIONINE; ZINC;

ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL TRANSLOCATION; COLONY FORMING UNIT; CONTROLLED STUDY; DIET SUPPLEMENTATION; GESTATION PERIOD; GOBLET CELL; ILEUM; INTESTINE; INTESTINE CRYPT; INTESTINE VILLUS; JEJUNUM; LYMPH NODE; MALE; MESENTERY LYMPH NODE; NONHUMAN; SOW (SWINE); STOMACH INTUBATION; SUCKLING; SWINE; WEANING;

ANIMALS; BACTERIAL TRANSLOCATION; DIETARY SUPPLEMENTS; ESCHERICHIA COLI; FEMALE; INTESTINE, SMALL; LIPOPOLYSACCHARIDES; METHIONINE; PREGNANCY; PREGNANCY, ANIMAL; SWINE; ZINC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; SUIDAE;

EID: 64549135094     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2008.10.005     Document Type: Article

References (65)

1. Andonova M., Borissov I., and Sotirov L. Changes in some factors of the innate immunity and serum zinc and iron concentrations in pigs following intravenous administration of Escherichia coli lipopolysaccharide. The Onderstepoort Journal of Veterinary Research 68 (2001) 91-99
2. Becker B.A., and Misfeldt M.L. Evaluation of the mitogen-induced proliferation and cell surface differentiation antigens of lymphocytes from pigs 1 to 30 days of age. Journal of Animal Science 71 (1993) 2073-2078
3. Berg R.D. Bacterial translocation from the gastrointestinal tract. Trends in Microbiology 3 (1995) 149-154
4. Blanchard R.K., and Cousins R.J. Differential display of intestinal mRNAs regulated by dietary zinc. Proceedings of the National Academy of Sciences of United States of America 93 (1996) 6863-6868
5. Braselton W.E., Stuart K.J., Mullaney T.P., and Herdt T.H. Biopsy mineral analysis by inductively coupled plasma-atomic emission spectroscopy with ultrasonic nebulization. Journal of Veterinary Diagnostic Investigation 9 (1997) 395-400
6. Brandao-Neto J., Stefan V., Mendonca B.B., Bloise W., and Castro A.V.B. The essential role of zinc in growth. Nutrition Research 15 (1995) 335-358
7. Broom L.J., Miller H.M., Kerr K.G., and Knapp J.S. Effects of zinc oxide and Enterococcus faecium SF68 dietary supplementation on the performance, intestinal microbiota and immune status of weaned pigs. Research in Veterinary Science 80 (2006) 45-54
8. Brunsgaard G. Effects of cereal type and feed particle size on morphological characteristics, epithelial cell proliferation, and lectin binding patterns in the large intestine of pigs. Journal of Animal Science 76 (1998) 2787-2798
9. Canadian Council on Animal Care. In: Olfert E.B., Cross B.M., and McWilliam A.A. (Eds). A Guide to the Care and Use of Experimental Animals. second ed. vol. 1 (1993), Canadian Council on Animal Care, Ottawa, ON
10. Case C.L., and Carlson M.S. Effect of feeding organic and inorganic sources of additional zinc on growth performance and zinc balance in nursery pigs. Journal of Animal Science 80 (2002) 1917-1924
11. Carlson M.S., Hill G.M., and Link J.E. Early- and traditionally weaned nursery pigs benefit from phase-feeding pharmacological concentration of zinc oxide: effect on metallothionein and mineral concentrations. Journal of Animal Science 77 (1999) 1199-1207
12. Carlson M.S., Boren C.A., Wu C., Huntington C.E., Bollinger D.W., and Veum T.L. Evaluation of various inclusion rates of organic zinc either as polysaccharide or proteinate complex on the growth performance, plasma, and excretion of nursery pigs. Journal of Animal Science 82 (2004) 1359-1366
13. Carlson D., Poulsen H.D., and Vestergaard M. Additional dietary zinc for weaning piglets is associated with elevated concentrations of serum IGF-I. Journal of Animal Physiology and Animal Nutrition 88 (2004) 332-339
14. Carlson D., Beattie J.H., and Poulsen H.D. Assessment of zinc and copper status in weaned piglets in relation to dietary zinc and copper supply. Journal of Animal Physiology and Animal Nutrition 91 (2007) 19-28
15. Castillo M., Martin-Orúe S.M., Taylor-Pickard J.A., Pérez J.F., and Gasa J. Use of mannan-oligosaccharides and zinc chelate as growth promoters and diarrhea preventative in weaning pigs: effects on microbiota and gut function. Journal of Animal Science 86 (2008) 94-101
16. Cerf-Bensussan N., and Guy-Grand D. Intestinal intraepithelial lymphocytes. Gastroenterology Clinics of North America 20 (1991) 549-576
17. Cousins R.J. Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. Physiological Reviews 65 (1985) 238-309
18. Daiwen C., Keying Z., and Chunyan W. Influences of lipopolysaccharide-induced immune challenge on performance and whole-body protein turnover in weanling pigs. Livestock Science 113 (2008) 291-295
19. Dritz S.S., Shi J., Kielian T.L., Goodband R.D., Nelssen J.L., Tokach M.D., Chengappa M.M., Smith J.E., and Blecha F. Influence of dietary β-glucan on growth performance, nonspecific immunity, and resistance to Streptococcus suis infection in weanling pigs. Journal of Animal Science 73 (1995) 3341-3350
20. Dritz S.S., Owen K.Q., Goodband R.D., Nelssen J.L., Tokach M.D., Chengappa M.M., and Blecha F. Influence of lipopolysaccharide-induced immune challenge and diet complexity on growth performance and acute-phase protein production in early-weaned pigs. Journal of Animal Science 74 (1996) 1620-1628
21. Egberts H.J.A., Koninkx J.F.J.G., van Dijk J.E., and Mouwen J.M.V.M. Biological and pathological aspects of the glycocalyx of the small intestinal epithelium. A review. Veterinary Quarterly 6 (1984) 186-199
22. Gaskins H.R., and Kelley K.W. Immunology and neonatal mortality. In: Varley M.A. (Ed). The Neonatal Pig Development and Survival (1995), CAB International, Wallingford, Oxon, UK 39-55
23. Hambidge K.M., Casey C.E., and Krebs N.F. Zinc. In: Mertz W. (Ed). Trace Elements in Human and Animal Nutrition (1986), Academic Press Inc., Orlando, FL, US 1-137
24. Hampson D.J. Alterations in piglet small intestinal structure at weaning. Research in Veterinary Science 40 (1986) 32-40
25. Hampson D.J., Pluske J.R., and Pethick D.W. Dietary manipulation of enteric disease. Pig News and Information 22 (2001) 21N-28N
26. Hedemann M.S., Højsgard S., and Jensen B.B. Small intestinal morphology and activity of intestinal peptidases in piglets around weaning. Journal of Animal Physiology and Animal Nutrition 87 (2003) 32-41
27. Hedemann M.S., Jensen B.B., and Poulsen H.D. Influence of dietary zinc and copper on digestive enzyme activity and intestinal morphology in weaned pigs. Journal of Animal Science 84 (2006) 3310-3320
28. Hollis G.R., Carter S.D., Cline T.R., Crenshaw T.D., Cromwell G.L., Hill G.M., Kim S.W., Lewis A.J., Mahan D.C., Miller P.S., Stein H.H., and Veum T.L. Effects of replacing pharmacological levels of dietary zinc oxide with lower dietary levels of various organic zinc sources for weanling pigs. Journal of Animal Science 84 (2005) 2123-2129
29. Huang S.X., McFall M., Cegielski A.C., and Kirkwood R.N. Effect of dietary zinc supplementation on Escherichia coli septicemia in weaned pigs. Swine Health Production 7 (1999) 109-111
30. Kaneko J.J. Clinical Biochemistry of Domestic Animals. fourth ed. (1989), Academic Press Inc., San Diego, CA, USA
31. Kelley K.W., Johnson R.W., and Dantzer R. Immunology discovers physiology. Veterinary Immunology and Immunopathology 43 (1994) 157-165
32. Kidd M.T., Ferket P.R., and Qureshi M.A. Zinc metabolism with special reference to its role in immunity. World's Poultry Science Journal 52 (1996) 309-324
33. Lambert E., Williams D.H., Lynch P.B., Hanrahan T.J., McGeady T.A., Austin F.H., Boland M.P., and Roche J.F. The extent and timing of prenatal loss in gilts. Theriogenology 36 (1991) 655-665
34. Lee G.R., Nacht S., Lukens J.N., and Cartwright G.E. Iron metabolism in copper-deficient swine. The Journal of Clinical Investigation 47 (1968) 2058-2069
35. Lee S.H., Lancey R., Montaser A., Madani N., and Linder M.C. Ceruloplasmin and copper transport during the latter part of gestation in the rat. Proceedings of the Society for Experimental Biology and Medicine 203 (1993) 428-439
36. Li B.T., Van Kessel A.G., Caine W.R., Huang S.X., and Kirkwood R.N. Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide. Canadian Journal of Animal Science 81 (2001) 511-516
37. Li X., Yin J., Li D., Chen X., Zang J., and Zhou X. Dietary supplementation with zinc oxide increases IGF-I and IGF-I receptor gene expression in the small intestine of weanling piglets. Journal of Nutrition 136 (2006) 1786-1791
38. Mack D.R., Ahrne S., Hyde L., Wei S., and Hollingsworth M.A. Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro. Gut 52 (2004) 827-833
39. Martínez M.M., Hill G.M., Link J.E., Raney N.E., Tempelman R.J., and Ernst C.W. Pharmacological zinc and phytase supplementation enhance metallothionein mRNA abundance and protein concentration in newly weaned pigs. Journal of Nutrition 134 (2004) 538-544
40. Mavromichalis I., Peter C.M., Parr T.M., Ganessunker D., and Baker D.H. Growth-promoting efficacy in young pigs of two sources of zinc oxide having either a high or a low bioavailability of zinc. Journal of Animal Science 78 (2000) 2896-2902
41. Milne D.B., and Matrone G. Forms of ceruloplasmin in developing piglets. Biochimica et Biophysica Acta 212 (1970) 43-49
42. Nabuurs M.J.A., Hoogendoom A., Molen E.J.v.d., and Osta A.L.M.v. Villus height and crypt depth in weaned and unweaned pigs, reared under various circumstances in the Netherlands. Research in Veterinary Science 55 (1993) 78-84
43. Namkung H., Gong J., Yu H., and de Lange C.F.M. Effect of pharmacological intakes of zinc and copper on growth performance, circulating cytokines and gut microbiota of newly weaned piglets challenged with coliform lipopolysaccharides. Canadian Journal of Animal Science 86 (2006) 511-522
44. National Research Council. Nutrient Requirements of Swine. 10th ed. (1998), National Academy Press, Washington, DC, USA
45. Núnez M.C., Bueno J.D., Ayudarte M.V., Almendros A., Rios A., Suárez M.D., and Gil A. Dietary restriction induces biochemical and morphometric changes in the small intestine of nursing piglets. Journal of Nutrition 126 (1996) 933-944
46. Osaki S., and Johnson D.A. Mobilization of liver iron by ferroxidase (ceruloplasmin). Journal of Biological Chemistry 244 (1969) 5757-5758
47. Payne R.L., Bidner T.D., Fakler T.M., and Southern L.L. Growth and intestinal morphology of pigs from sows fed two zinc sources during gestation and lactation. Journal of Animal Science 84 (2006) 2141-2149
48. Peterson D.G., Scrimgeour A.G., McClung J.P., and Koutsos E. Moderate zinc restriction affects intestinal health and immune function in lipopolysaccharide-challenged mice. Journal of Nutritional Biochemistry 19 (2008) 193-199
49. Pluske J.R. Morphological and functional changes in the small intestine of the newly-weaned pig. In: Piva A., Bach Knudsen K.E., and Lindberg J.E. (Eds). Gut Environment of Pigs (2001), Nottingham University Press, Nottingham, UK 1-27
50. Pluske J.R., Hampson D.J., and Williams I.H. Factors influencing the structure and function of the small intestine in the weaned pig: a review. Livestock Production Science 51 (1997) 215-236
51. Poulsen H.D. Zinc oxide for weanling piglets. Acta Agriculturae Scandinavica: Section A, Animal Science 45 (1995) 159-167
52. Quinn P.J., Carter M.E., Markey B., and Carter G.R. Clinical Veterinary Microbiology (1994), Wolfe Publishing, Mosby-Year Book Europe Limited, London pp. 220-284
53. Reeves P.G., Rossow K.L., and Bobilya D.J. Zinc-induced metallothionein and copper metabolism in intestinal mucosa, liver, and kidney of rats. Nutrition Research 14 (1994) 897-908
54. Richards M.P. Zinc, copper, and iron metabolism during porcine fetal development. Biological Trace Element Research 69 (1999) 27-44
55. Richards M.P., and Cousins R.J. Mammalian zinc homeostasis: requirement for RNA and metallothionein synthesis. Biochemical and Biophysical Research Communications 64 (1975) 1215-1223
56. Rincker M.J., Hill G.M., Link J.E., Meyer M., and Rowntree J.E. Effects of dietary zinc and iron supplementation on mineral excretion, body composition, and mineral status of nursery pigs. Journal of Animal Science 83 (2005) 2762-2774
57. Shankar A.H., and Prasad A.S. Zinc and immune function: the biological basis of altered resistance to infection. American Journal of Clinical Nutrition 68 (1998) 447S-463S
58. Shou J., Motyka L.E., and Daly J.M. Intestinal microbial translocation: Immunologic consequences and effects of interleukin-4. Surgery 116 (1994) 868-876
59. Statistical Analysis System. SAS/STAT User's Guide. Version 9.1 (2003), SAS Inst. Inc., Cary, NC, USA
60. Stokes C.R., Bailey M., and Wilson A.D. Immunology of the porcine gastrointestinal tract. Veterinary Immunology and Immunopathology 43 (1994) 143-150
61. Tako E., Ferket P.R., and Uni Z. Changes in chicken intestinal zinc exporter mRNA expression and small intestinal functionality following intra-amniotic zinc-methionine administration. Journal of Nutritional Biochemistry 16 (2005) 339-346
62. Tang M., Laarveld B., Van Kessel A.G., Hamilton D.L., Estrada A., and Patience J.F. Effect of segregated early weaning on postweaning small intestinal development in pigs. Journal of Animal Science 77 (1999) 3191-3200
63. Van Heughten E., Spears J.W., Kegley E.B., Ward J.D., and Qureshi M.A. Effects of organic forms of zinc on growth performance, tissue zinc distribution, and immune response of weanling pigs. Journal of Animal Science 81 (2003) 2063-2071
64. Warren E.J., Fink B.N., Arkins S., Kelley K.W., Scamurra R.W., Murtaugh M.P., and Johnson R.W. Coincidental changes in behaviour and plasma cortisol in unrestrained pigs after intracerebroventricular injection of tumor necrosis factor-α. Endocrinology 138 (1997) 2365-2371
65. Wright K.J., Balaji R., Hill C.M., Dritz S.S., Knoppel E.L., and Minton J.E. Integrated adrenal, somatropic, and immune responses of growing pigs to treatment with lipopolysaccharide. Journal of Animal Science 78 (2000) 1892-1899