메뉴 건너뛰기




Volumn 58, Issue 4, 2013, Pages 1016-1025

The down-regulation of Notch1 inhibits the invasion and migration of hepatocellular carcinoma cells by inactivating the cyclooxygenase-2/snail/E- cadherin pathway in vitro

Author keywords

Cyclooxygenase 2; E cadherin; Invasion; Migration; Notch1 signaling pathway; Snail

Indexed keywords

CYCLOOXYGENASE 2; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NOTCH1 RECEPTOR; PROSTAGLANDIN E2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN;

EID: 84876669014     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2434-7     Document Type: Article
Times cited : (40)

References (47)
  • 2
    • 0033947630 scopus 로고    scopus 로고
    • Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma
    • 10862190 10.1097/00000658-200007000-00003 1:STN:280: DC%2BD3czitVCrug%3D%3D
    • Tung-Ping Poon R, Fan ST, Wong J. Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma. Ann Surg. 2000;232:10-24.
    • (2000) Ann Surg , vol.232 , pp. 10-24
    • Tung-Ping Poon, R.1    Fan, S.T.2    Wong, J.3
  • 3
    • 1042267263 scopus 로고    scopus 로고
    • Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
    • 14964308 10.1038/nrc1276 1:CAS:528:DC%2BD2cXhtlaquro%3D
    • Cavallaro U, Christofori G. Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat Rev Cancer. 2004;4:118-132.
    • (2004) Nat Rev Cancer , vol.4 , pp. 118-132
    • Cavallaro, U.1    Christofori, G.2
  • 4
    • 0042762970 scopus 로고    scopus 로고
    • Prognostic significance of E-cadherin and beta-catenin in resected stage i non-small cell lung cancer
    • 12965318 10.1016/S1010-7940(03)00308-7 1:CAS:528:DC%2BD3sXkt1OhtLw%3D
    • Choi YS, Shim YM, Kim SH, et al. Prognostic significance of E-cadherin and beta-catenin in resected stage I non-small cell lung cancer. Eur J Cardiothorac Surg. 2003;24:441-449.
    • (2003) Eur J Cardiothorac Surg , vol.24 , pp. 441-449
    • Choi, Y.S.1    Shim, Y.M.2    Kim, S.H.3
  • 5
    • 0037093230 scopus 로고    scopus 로고
    • High-throughput tissue microarray analysis used to evaluate biology and prognostic significance of the E-cadherin pathway in non-small-cell lung cancer
    • 12011119 10.1200/JCO.2002.08.159 1:CAS:528:DC%2BD38XksFakur4%3D
    • Bremnes RM, Veve R, Gabrielson E, et al. High-throughput tissue microarray analysis used to evaluate biology and prognostic significance of the E-cadherin pathway in non-small-cell lung cancer. J Clin Oncol. 2002;20:2417-2428.
    • (2002) J Clin Oncol , vol.20 , pp. 2417-2428
    • Bremnes, R.M.1    Veve, R.2    Gabrielson, E.3
  • 6
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • 8521479 10.1016/0092-8674(95)90127-2 1:CAS:528:DyaK2MXpt1Olt7w%3D
    • Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell. 1995;83:493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    Dubois, R.N.2
  • 7
    • 0035105335 scopus 로고    scopus 로고
    • E-cadherin expression associated with differentiation and prognosis in patients with non-small cell lung cancer
    • 11269479 10.1016/S0003-4975(00)02545-5 1:STN:280:DC%2BD3M7mvVWgug%3D%3D (discussion 954-955)
    • Liu D, Huang C, Kameyama K, et al. E-cadherin expression associated with differentiation and prognosis in patients with non-small cell lung cancer. Ann Thorac Surg. 2001;71:949-954. (discussion 954-955).
    • (2001) Ann Thorac Surg , vol.71 , pp. 949-954
    • Liu, D.1    Huang, C.2    Kameyama, K.3
  • 8
    • 0036725378 scopus 로고    scopus 로고
    • Altered expression of E-cadherin in hepatocellular carcinoma: Correlations with genetic alterations, beta-catenin expression, and clinical features
    • 12198663 10.1053/jhep.2002.35342 1:CAS:528:DC%2BD38XnvVSktLk%3D
    • Wei Y, Van Nhieu JT, Prigent S, Srivatanakul P, Tiollais P, Buendia MA. Altered expression of E-cadherin in hepatocellular carcinoma: correlations with genetic alterations, beta-catenin expression, and clinical features. Hepatology. 2002;36:692-701.
    • (2002) Hepatology , vol.36 , pp. 692-701
    • Wei, Y.1    Van Nhieu, J.T.2    Prigent, S.3    Srivatanakul, P.4    Tiollais, P.5    Buendia, M.A.6
  • 9
    • 18844464056 scopus 로고    scopus 로고
    • Identification of the familial cylindromatosis tumour-suppressor gene
    • 10835629 10.1038/76006 1:CAS:528:DC%2BD3cXjvFOgt7g%3D
    • Bignell GR, Warren W, Seal S, et al. Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet. 2000;25:160-165.
    • (2000) Nat Genet , vol.25 , pp. 160-165
    • Bignell, G.R.1    Warren, W.2    Seal, S.3
  • 10
    • 0029975798 scopus 로고    scopus 로고
    • E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma
    • 8938181 10.1002/hep.510240627 1:CAS:528:DyaK2sXpt1Clsg%3D%3D
    • Osada T, Sakamoto M, Ino Y, et al. E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma. Hepatology. 1996;24:1460-1467.
    • (1996) Hepatology , vol.24 , pp. 1460-1467
    • Osada, T.1    Sakamoto, M.2    Ino, Y.3
  • 11
    • 0035392961 scopus 로고    scopus 로고
    • An intact overexpressed E-cadherin/alpha, beta-catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma
    • 11431364 1:CAS:528:DC%2BD3MXltVCjs78%3D
    • Tomlinson JS, Alpaugh ML, Barsky SH. An intact overexpressed E-cadherin/alpha, beta-catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma. Cancer Res. 2001;61:5231-5241.
    • (2001) Cancer Res , vol.61 , pp. 5231-5241
    • Tomlinson, J.S.1    Alpaugh, M.L.2    Barsky, S.H.3
  • 13
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • 9515965 10.1038/32433 1:CAS:528:DyaK1cXhvFelsL4%3D
    • Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature. 1998;392:190-193.
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 14
    • 24944450362 scopus 로고    scopus 로고
    • The transcriptional repressor Snail promotes mammary tumor recurrence
    • 16169465 10.1016/j.ccr.2005.07.009 1:CAS:528:DC%2BD2MXhtV2gt7rF
    • Moody SE, Perez D, Pan TC, et al. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell. 2005;8:197-209.
    • (2005) Cancer Cell , vol.8 , pp. 197-209
    • Moody, S.E.1    Perez, D.2    Pan, T.C.3
  • 15
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • 10221902 10.1126/science.284.5415.770 1:CAS:528:DyaK1MXivVKrs7Y%3D
    • Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science. 1999;284:770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 16
    • 0032695278 scopus 로고    scopus 로고
    • Arbiter of differentiation and death: Notch signaling meets apoptosis
    • 10528225 10.1002/(SICI)1097-4652(199912)181:3<393: AID-JCP3>3.0.CO;2-6 1:CAS:528:DyaK1MXnt1Smtb0%3D
    • Miele L, Osborne B. Arbiter of differentiation and death: Notch signaling meets apoptosis. J Cell Physiol. 1999;181:393-409.
    • (1999) J Cell Physiol , vol.181 , pp. 393-409
    • Miele, L.1    Osborne, B.2
  • 17
    • 38049150094 scopus 로고    scopus 로고
    • Deregulated expression of Notch receptors in human hepatocellular carcinoma
    • 17920003 10.1016/j.dld.2007.08.001 1:CAS:528:DC%2BD1cXjvF2it7Y%3D
    • Gao J, Song Z, Chen Y, et al. Deregulated expression of Notch receptors in human hepatocellular carcinoma. Dig Liver Dis. 2008;40:114-121.
    • (2008) Dig Liver Dis , vol.40 , pp. 114-121
    • Gao, J.1    Song, Z.2    Chen, Y.3
  • 18
    • 84861573132 scopus 로고    scopus 로고
    • Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma
    • 22052196 10.1002/ijc.27336 1:CAS:528:DC%2BC3MXhs1Squ7nE
    • Wang XQ, Zhang W, Lui EL, et al. Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma. Int J Cancer. 2012;131:E163-E172.
    • (2012) Int J Cancer , vol.131
    • Wang, X.Q.1    Zhang, W.2    Lui, E.L.3
  • 19
    • 44049090235 scopus 로고    scopus 로고
    • Notch signaling mediates hypoxia-induced tumor cell migration and invasion
    • 18427106 10.1073/pnas.0802047105 1:CAS:528:DC%2BD1cXlsFyhtbs%3D
    • Sahlgren C, Gustafsson MV, Jin S, Poellinger L, Lendahl U. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci USA. 2008;105:6392-6397.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6392-6397
    • Sahlgren, C.1    Gustafsson, M.V.2    Jin, S.3    Poellinger, L.4    Lendahl, U.5
  • 20
    • 82255167651 scopus 로고    scopus 로고
    • Notch1 binds and induces degradation of Snail in hepatocellular carcinoma
    • 22128911 10.1186/1741-7007-9-83 1:CAS:528:DC%2BC38XltFWquw%3D%3D
    • Lim SO, Kim HS, Quan X, et al. Notch1 binds and induces degradation of Snail in hepatocellular carcinoma. BMC Biol. 2011;9:83.
    • (2011) BMC Biol , vol.9 , pp. 83
    • Lim, S.O.1    Kim, H.S.2    Quan, X.3
  • 21
    • 67449168389 scopus 로고    scopus 로고
    • The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2
    • 19491270 10.1158/0008-5472.CAN-08-4021 1:CAS:528:DC%2BD1MXnt1eqtbs%3D
    • Yeh TS, Wu CW, Hsu KW, et al. The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2. Cancer Res. 2009;69:5039-5048.
    • (2009) Cancer Res , vol.69 , pp. 5039-5048
    • Yeh, T.S.1    Wu, C.W.2    Hsu, K.W.3
  • 22
    • 0028142232 scopus 로고
    • Adhesion molecules: Novel molecular tools in tumor pathology
    • 8088758 10.1016/0046-8177(94)90002-7 1:CAS:528:DyaK2cXmsFamtbc%3D
    • Pignatelli M, Vessey CJ. Adhesion molecules: novel molecular tools in tumor pathology. Hum Pathol. 1994;25:849-856.
    • (1994) Hum Pathol , vol.25 , pp. 849-856
    • Pignatelli, M.1    Vessey, C.J.2
  • 23
    • 0027185632 scopus 로고
    • From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
    • 8236461 10.1016/0168-9525(93)90250-L 1:CAS:528:DyaK3sXmsVelsLo%3D
    • Kemler R. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 1993;9:317-321.
    • (1993) Trends Genet , vol.9 , pp. 317-321
    • Kemler, R.1
  • 25
    • 0029889851 scopus 로고    scopus 로고
    • The E-cadherin/catenin complex in invasion and metastasis
    • 8814984 10.1007/978-3-642-61107-0-9 1:CAS:528:DyaK28XksVamur0%3D
    • Bracke ME, Van Roy FM, Mareel MM. The E-cadherin/catenin complex in invasion and metastasis. Curr Top Microbiol Immunol. 1996;213:123-161.
    • (1996) Curr Top Microbiol Immunol , vol.213 , pp. 123-161
    • Bracke, M.E.1    Van Roy, F.M.2    Mareel, M.M.3
  • 26
    • 0033079605 scopus 로고    scopus 로고
    • The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
    • 10098402 10.1016/S0968-0004(98)01343-7 1:CAS:528:DyaK1MXltFCgsr8%3D
    • Christofori G, Semb H. The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene. Trends Biochem Sci. 1999;24:73-76.
    • (1999) Trends Biochem Sci , vol.24 , pp. 73-76
    • Christofori, G.1    Semb, H.2
  • 27
    • 0034067979 scopus 로고    scopus 로고
    • Immunoreactive E-cadherin, alpha-catenin, beta-catenin, and gamma-catenin proteins in hepatocellular carcinoma: Relationships with tumor grade, clinicopathologic parameters, and patients' survival
    • 10836294 10.1053/hp.2000.6683 1:CAS:528:DC%2BD3cXjvFShtLw%3D
    • Endo K, Ueda T, Ueyama J, Ohta T, Terada T. Immunoreactive E-cadherin, alpha-catenin, beta-catenin, and gamma-catenin proteins in hepatocellular carcinoma: relationships with tumor grade, clinicopathologic parameters, and patients' survival. Hum Pathol. 2000;31:558-565.
    • (2000) Hum Pathol , vol.31 , pp. 558-565
    • Endo, K.1    Ueda, T.2    Ueyama, J.3    Ohta, T.4    Terada, T.5
  • 28
    • 47549098263 scopus 로고    scopus 로고
    • E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas
    • 18600305 10.1007/s10585-008-9167-1 1:CAS:528:DC%2BD1cXhtVeisL7J
    • Wells A, Yates C, Shepard CR. E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas. Clin Exp Metastasis. 2008;25:621-628.
    • (2008) Clin Exp Metastasis , vol.25 , pp. 621-628
    • Wells, A.1    Yates, C.2    Shepard, C.R.3
  • 29
    • 34548078651 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition: Expression of the regulators snail, slug, and twist in pancreatic cancer
    • 17699854 10.1158/1078-0432.CCR-06-2926 1:CAS:528:DC%2BD2sXptVGmtrY%3D
    • Hotz B, Arndt M, Dullat S, Bhargava S, Buhr HJ, Hotz HG. Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer. Clin Cancer Res. 2007;13:4769-4776.
    • (2007) Clin Cancer Res , vol.13 , pp. 4769-4777
    • Hotz, B.1    Arndt, M.2    Dullat, S.3    Bhargava, S.4    Buhr, H.J.5    Hotz, H.G.6
  • 30
    • 33750358078 scopus 로고    scopus 로고
    • Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial- mesenchymal transition
    • 17018611 10.1158/0008-5472.CAN-06-0479 1:CAS:528:DC%2BD28XhtVamsrfE
    • Moreno-Bueno G, Cubillo E, Sarrio D, et al. Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res. 2006;66:9543-9556.
    • (2006) Cancer Res , vol.66 , pp. 9543-9556
    • Moreno-Bueno, G.1    Cubillo, E.2    Sarrio, D.3
  • 31
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • 10655586 10.1038/35000025 1:CAS:528:DC%2BD3cXhtVyltLw%3D
    • Cano A, Perez-Moreno MA, Rodrigo I, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol. 2000;2:76-83.
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3
  • 32
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • 10655587 10.1038/35000034 1:CAS:528:DC%2BD3cXhtVyltLo%3D
    • Batlle E, Sancho E, Franci C, et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol. 2000;2:84-89.
    • (2000) Nat Cell Biol , vol.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Franci, C.3
  • 33
    • 0035215136 scopus 로고    scopus 로고
    • Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro
    • 11120485 10.1016/S1368-8375(00)00059-2 1:CAS:528:DC%2BD3cXovFKgsbY%3D
    • Yokoyama K, Kamata N, Hayashi E, et al. Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro. Oral Oncol. 2001;37:65-71.
    • (2001) Oral Oncol , vol.37 , pp. 65-71
    • Yokoyama, K.1    Kamata, N.2    Hayashi, E.3
  • 34
    • 0037033693 scopus 로고    scopus 로고
    • Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo
    • 11857019 10.1038/sj.bjc.6600017 1:CAS:528:DC%2BD38Xit1Wgtr8%3D
    • Jiao W, Miyazaki K, Kitajima Y. Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo. Br J Cancer. 2002;86:98-101.
    • (2002) Br J Cancer , vol.86 , pp. 98-101
    • Jiao, W.1    Miyazaki, K.2    Kitajima, Y.3
  • 35
    • 27644490306 scopus 로고    scopus 로고
    • Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression
    • 16239965 10.1172/JCI25001 1:CAS:528:DC%2BD2MXhtF2kt7rK
    • Balint K, Xiao M, Pinnix CC, et al. Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression. J Clin Invest. 2005;115:3166-3176.
    • (2005) J Clin Invest , vol.115 , pp. 3166-3176
    • Balint, K.1    Xiao, M.2    Pinnix, C.C.3
  • 36
    • 28244469644 scopus 로고    scopus 로고
    • The Notch signaling pathway is related to neurovascular progression of pancreatic cancer
    • 16327489 10.1097/01.sla.0000189115.94847.f1 (discussion 800-801)
    • Buchler P, Gazdhar A, Schubert M, et al. The Notch signaling pathway is related to neurovascular progression of pancreatic cancer. Ann Surg. 2005;242:791-800. (discussion 800-801).
    • (2005) Ann Surg , vol.242 , pp. 791-800
    • Buchler, P.1    Gazdhar, A.2    Schubert, M.3
  • 37
    • 33645049305 scopus 로고    scopus 로고
    • Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells
    • 16510599 10.1158/0008-5472.CAN-05-4281 1:CAS:528:DC%2BD28XhvV2gtr8%3D
    • Wang Z, Banerjee S, Li Y, Rahman KM, Zhang Y, Sarkar FH. Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. Cancer Res. 2006;66:2778-2784.
    • (2006) Cancer Res , vol.66 , pp. 2778-2784
    • Wang, Z.1    Banerjee, S.2    Li, Y.3    Rahman, K.M.4    Zhang, Y.5    Sarkar, F.H.6
  • 38
    • 9144246932 scopus 로고    scopus 로고
    • Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
    • 14701881 10.1101/gad.276304 1:CAS:528:DC%2BD2cXotFOhtQ%3D%3D
    • Timmerman LA, Grego-Bessa J, Raya A, et al. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev. 2004;18:99-115.
    • (2004) Genes Dev , vol.18 , pp. 99-115
    • Timmerman, L.A.1    Grego-Bessa, J.2    Raya, A.3
  • 39
    • 11144354703 scopus 로고    scopus 로고
    • Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation
    • 14988227 10.1161/01.RES.0000124300.76171.C9 1:CAS:528: DC%2BD2cXivVKqs7Y%3D
    • Noseda M, McLean G, Niessen K, et al. Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circ Res. 2004;94:910-917.
    • (2004) Circ Res , vol.94 , pp. 910-917
    • Noseda, M.1    McLean, G.2    Niessen, K.3
  • 41
    • 0346368096 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 in human neoplasia: Rationale and promise
    • 14706335 10.1016/S1535-6108(03)00310-6 1:CAS:528:DC%2BD2cXitFKquw%3D%3D
    • Dannenberg AJ, Subbaramaiah K. Targeting cyclooxygenase-2 in human neoplasia: rationale and promise. Cancer Cell. 2003;4:431-436.
    • (2003) Cancer Cell , vol.4 , pp. 431-436
    • Dannenberg, A.J.1    Subbaramaiah, K.2
  • 42
    • 0032863550 scopus 로고    scopus 로고
    • Chemoprevention of colorectal cancer through inhibition of cyclooxygenase-2
    • 10528897 1:CAS:528:DyaK1MXntFOktLc%3D
    • Dannenberg AJ, Zakim D. Chemoprevention of colorectal cancer through inhibition of cyclooxygenase-2. Semin Oncol. 1999;26:499-504.
    • (1999) Semin Oncol , vol.26 , pp. 499-504
    • Dannenberg, A.J.1    Zakim, D.2
  • 43
    • 0032521401 scopus 로고    scopus 로고
    • Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin 10 and down-regulation of interleukin 12 production
    • 9515807 1:CAS:528:DyaK1cXhvV2rs7w%3D
    • Huang M, Stolina M, Sharma S, et al. Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production. Cancer Res. 1998;58:1208-1216.
    • (1998) Cancer Res , vol.58 , pp. 1208-1216
    • Huang, M.1    Stolina, M.2    Sharma, S.3
  • 44
    • 33751160398 scopus 로고    scopus 로고
    • Cox-2 expression on tissue microarray of breast cancer
    • 16797158 10.1016/j.ejso.2006.05.010 1:STN:280:DC%2BD28novVersA%3D%3D
    • Park K, Han S, Shin E, Kim HJ, Kim JY. Cox-2 expression on tissue microarray of breast cancer. Eur J Surg Oncol. 2006;32:1093-1096.
    • (2006) Eur J Surg Oncol , vol.32 , pp. 1093-1096
    • Park, K.1    Han, S.2    Shin, E.3    Kim, H.J.4    Kim, J.Y.5
  • 45
    • 0346736504 scopus 로고    scopus 로고
    • Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion
    • 12393872 10.1074/jbc.M210707200 1:CAS:528:DC%2BD38Xps12ntb0%3D
    • Dohadwala M, Batra RK, Luo J, et al. Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem. 2002;277:50828-50833.
    • (2002) J Biol Chem , vol.277 , pp. 50828-50833
    • Dohadwala, M.1    Batra, R.K.2    Luo, J.3
  • 46
    • 33744925683 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent regulation of E-cadherin: Prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
    • 16707460 10.1158/0008-5472.CAN-05-3635 1:CAS:528:DC%2BD28XksF2isbw%3D
    • Dohadwala M, Yang SC, Luo J, et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res. 2006;66:5338-5345.
    • (2006) Cancer Res , vol.66 , pp. 5338-5345
    • Dohadwala, M.1    Yang, S.C.2    Luo, J.3
  • 47
    • 0036857487 scopus 로고    scopus 로고
    • Effects of etodolac, a selective cyclooxygenase-2 inhibitor, on the expression of E-cadherin-catenin complexes in gastrointestinal cell lines
    • 12483244 10.1007/s005350200151 1:CAS:528:DC%2BD38XptFGisL8%3D
    • Noda M, Tatsumi Y, Tomizawa M, et al. Effects of etodolac, a selective cyclooxygenase-2 inhibitor, on the expression of E-cadherin-catenin complexes in gastrointestinal cell lines. J Gastroenterol. 2002;37:896-904.
    • (2002) J Gastroenterol , vol.37 , pp. 896-904
    • Noda, M.1    Tatsumi, Y.2    Tomizawa, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.