Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 3, 2010, Pages

  Bao, Jun Xiang ^a   Xia, Min ^a   Poklis, Justin L ^a   Han, Wei Qing ^a   Brimson, Christopher ^a   Li, Pin Lan ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acid vesicles; Coronary circulation; Membrane microdomains; Sphingolipids; Vascular endothelium

Indexed keywords

ARSENIC TRIOXIDE; BAFILOMYCINE; BUTYRIC ACID; CERAMIDE; DEATH RECEPTOR; FAS LIGAND; MEMBRANE LIPID; PHOSPHATE; PHOSPHATIDYLINOSITOL; PROTEIN INHIBITOR; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; VACUOLIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASM GENE; CELL FUSION; CELL MEMBRANE; CELL SURFACE; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; ELECTROSPRAY MASS SPECTROMETRY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; FLUORESCENCE ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE; GENE SILENCING; LIPID RAFT; LIQUID CHROMATOGRAPHY; LYSOSOME; LYSOSOME MEMBRANE; MEMBRANE FUSION; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; SYNTHESIS; TANDEM MASS SPECTROMETRY; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; CATTLE; CELL MEMBRANE; CELLS, CULTURED; CERAMIDES; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; FAS LIGAND PROTEIN; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOMES; MEMBRANE FUSION; MEMBRANE MICRODOMAINS; MODELS, ANIMAL; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 77749264336     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00958.2009     Document Type: Article

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