Sequential inductions of the ZEB1 transcription factor caused by mutation of Rb and then Ras proteins are required for tumor initiation and progression

Journal of Biological Chemistry

Volumn 288, Issue 16, 2013, Pages 11572-11580

  Liu, Yongqing ^a,b   Sánchez Tilló, Ester ^c   Lu, Xiaoqin ^b   Huang, Li ^b,f   Clem, Brian ^a   Telang, Sucheta ^a   Jenson, Alfred B ^a   Cuatrecasas, Miriam ^e   Chesney, Jason ^a   Postigo, Antonio ^a,c,d   Dean, Douglas C ^a,b  

^a UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

^b University of Louisville School of Medicine   (United States)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e UNIVERSITY OF BARCELONA   (Spain)

^f ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTORS;

TUMORS;

CYCLIN DEPENDENT KINASE INHIBITOR; MICRORNA 200; RAS PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR ZEB1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL AGING; CELL CONTACT; CELL CYCLE REGULATION; CELL IMMORTALIZATION; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; FIBROBLAST CULTURE; GENE EXPRESSION; GENE MUTATION; GENE REPRESSION; METASTASIS; MOUSE; MOUSE EMBRYO FIBROBLAST; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; SOLID TUMOR; TUMOR INVASION;

ANIMALS; CELL AGING; CELL TRANSFORMATION, NEOPLASTIC; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, NUDE; MICRORNAS; MUTATION; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASMS; RAS PROTEINS; RETINOBLASTOMA PROTEIN; RNA, NEOPLASM;

EID: 84876566047     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.434951     Document Type: Article

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