메뉴 건너뛰기




Volumn 34, Issue 1, 2012, Pages 27-36

Waterborne manganese exposure alters plasma, brain, and liver metabolites accompanied by changes in stereotypic behaviors

Author keywords

Behavior; Biomarker; Circadian rhythm; Manganese; Metabolomics; Neurotoxicity

Indexed keywords

ASPARTIC ACID; BIOLOGICAL MARKER; CHENODEOXYCHOLIC ACID; FATTY ACID; HYDROXYBUTYRIC ACID; MANGANESE; OLEIC ACID; PALMITIC ACID;

EID: 82655169242     PISSN: 08920362     EISSN: 18729738     Source Type: Journal    
DOI: 10.1016/j.ntt.2011.10.003     Document Type: Article
Times cited : (37)

References (62)
  • 1
    • 33845972636 scopus 로고    scopus 로고
    • Inhibition of DAT function attenuates manganese accumulation in the globus pallidus
    • Anderson J.G., Cooney P.T., Erikson K.M. Inhibition of DAT function attenuates manganese accumulation in the globus pallidus. Environ Toxicol Pharmacol 2007, 23:179-184.
    • (2007) Environ Toxicol Pharmacol , vol.23 , pp. 179-184
    • Anderson, J.G.1    Cooney, P.T.2    Erikson, K.M.3
  • 2
    • 56249101317 scopus 로고    scopus 로고
    • Manganese exposure alters extracellular GABA, GABA receptor and transporter protein and mRNA levels in the developing rat brain
    • Anderson J.G., Fordahl S.C., Cooney P.T., Weaver T.L., Colyer C.L., Erikson K.M. Manganese exposure alters extracellular GABA, GABA receptor and transporter protein and mRNA levels in the developing rat brain. NeuroTox 2008, 29:1044-1053.
    • (2008) NeuroTox , vol.29 , pp. 1044-1053
    • Anderson, J.G.1    Fordahl, S.C.2    Cooney, P.T.3    Weaver, T.L.4    Colyer, C.L.5    Erikson, K.M.6
  • 3
    • 0016423788 scopus 로고
    • The modifying effect of manganese on the enzymic profiles and pathways of carbohydrate metabolism in rat liver and adipose tissue during development
    • Baquer N.Z., Nothersall J.S., Greenbaum A.L., McLean P. The modifying effect of manganese on the enzymic profiles and pathways of carbohydrate metabolism in rat liver and adipose tissue during development. Biochem Biophys Res Commun 1974, 62(3):634-641.
    • (1974) Biochem Biophys Res Commun , vol.62 , Issue.3 , pp. 634-641
    • Baquer, N.Z.1    Nothersall, J.S.2    Greenbaum, A.L.3    McLean, P.4
  • 4
    • 33846013944 scopus 로고    scopus 로고
    • Hair manganese and hyperactive behaviors: pilot study of school-age children exposed through tap water
    • Bouchard M.F., Laforest F., Vandelac L., Bellinger D., Mergler D. Hair manganese and hyperactive behaviors: pilot study of school-age children exposed through tap water. EHP 2007, 115(1):122-127.
    • (2007) EHP , vol.115 , Issue.1 , pp. 122-127
    • Bouchard, M.F.1    Laforest, F.2    Vandelac, L.3    Bellinger, D.4    Mergler, D.5
  • 6
    • 0028281820 scopus 로고
    • Dietary manganese deficiency decreases rat hepatic arginase activity
    • Brock A.A., Chapman S.A., Ulman E.A., Wu G. Dietary manganese deficiency decreases rat hepatic arginase activity. J Nutr 1994, 124(3):340-344.
    • (1994) J Nutr , vol.124 , Issue.3 , pp. 340-344
    • Brock, A.A.1    Chapman, S.A.2    Ulman, E.A.3    Wu, G.4
  • 7
    • 78650572356 scopus 로고    scopus 로고
    • Manganese induces tau hyperphosphorylation through the activation of ERK MAPK pathway in PC12 cells
    • Cai T., Che H., Yao T., Chen Y., Huang C., Zhang W., Du K., Zhang J., Cao Y., Chen J., Luo W. Manganese induces tau hyperphosphorylation through the activation of ERK MAPK pathway in PC12 cells. Toxicol Sci 2011, 119(1):169-177.
    • (2011) Toxicol Sci , vol.119 , Issue.1 , pp. 169-177
    • Cai, T.1    Che, H.2    Yao, T.3    Chen, Y.4    Huang, C.5    Zhang, W.6    Du, K.7    Zhang, J.8    Cao, Y.9    Chen, J.10    Luo, W.11
  • 9
    • 1842557666 scopus 로고    scopus 로고
    • Circadian rhythms of dopamine, glutamate and GABA in the striatum and nucleus accumbens of the awake rat: modulation by light
    • Castaneda T.R., de Prado B.M., Prieto D., Francisco M. Circadian rhythms of dopamine, glutamate and GABA in the striatum and nucleus accumbens of the awake rat: modulation by light. J Pineal Res 2004, 177-185.
    • (2004) J Pineal Res , pp. 177-185
    • Castaneda, T.R.1    de Prado, B.M.2    Prieto, D.3    Francisco, M.4
  • 10
    • 33746866754 scopus 로고    scopus 로고
    • The diagnosis of manganese-induced parkinsonism
    • Cersosimo M.G., Koller W.C. The diagnosis of manganese-induced parkinsonism. NeuroTox 2006, 27:340-346.
    • (2006) NeuroTox , vol.27 , pp. 340-346
    • Cersosimo, M.G.1    Koller, W.C.2
  • 11
    • 0030455852 scopus 로고    scopus 로고
    • Effects of iron deficiency and iron overload on manganese uptake and deposition in the brain and other organs of the rat
    • Chua A.C., Morgan E.H. Effects of iron deficiency and iron overload on manganese uptake and deposition in the brain and other organs of the rat. Biol Trace Elem Res 1996, 55(1-2):39-54.
    • (1996) Biol Trace Elem Res , vol.55 , Issue.1-2 , pp. 39-54
    • Chua, A.C.1    Morgan, E.H.2
  • 12
    • 0035807750 scopus 로고    scopus 로고
    • Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741
    • Chun H.S., Lee H., Son J.H. Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741. Neurosci Lett 2001, 316:5-8.
    • (2001) Neurosci Lett , vol.316 , pp. 5-8
    • Chun, H.S.1    Lee, H.2    Son, J.H.3
  • 13
    • 71049181470 scopus 로고    scopus 로고
    • Manganese exposure among smelting workers: relationship between blood manganese-iron ratio and early onset neurobehavioral alterations
    • Cowan D.M., Zheng W., Zou Y., Shi X., Chen J., Rosenthal F.S., Fan Q. Manganese exposure among smelting workers: relationship between blood manganese-iron ratio and early onset neurobehavioral alterations. NeuroTox 2009, 30(6):1214-1222.
    • (2009) NeuroTox , vol.30 , Issue.6 , pp. 1214-1222
    • Cowan, D.M.1    Zheng, W.2    Zou, Y.3    Shi, X.4    Chen, J.5    Rosenthal, F.S.6    Fan, Q.7
  • 14
    • 12344250905 scopus 로고    scopus 로고
    • Manganese toxicity upon overexposure
    • Crossgrove J., Zheng W. Manganese toxicity upon overexposure. NMR Biomed 2004, 17:544-553.
    • (2004) NMR Biomed , vol.17 , pp. 544-553
    • Crossgrove, J.1    Zheng, W.2
  • 15
    • 0026579605 scopus 로고
    • Longitudinal changes of manganese-dependent superoxide dismutase and other indexes of manganese and iron status in women
    • Davis C.D., Greger J.L. Longitudinal changes of manganese-dependent superoxide dismutase and other indexes of manganese and iron status in women. Am J Clin Nutr 1992, 55(3):747-752.
    • (1992) Am J Clin Nutr , vol.55 , Issue.3 , pp. 747-752
    • Davis, C.D.1    Greger, J.L.2
  • 16
    • 84856234916 scopus 로고    scopus 로고
    • Behavioral pattern analysis and dopamine release in quinpirole-induced repetitive behavior in rats
    • de Haas R., Nijdam A., Westra T.A., Kas M.J.H., Westenberg H.G.M. Behavioral pattern analysis and dopamine release in quinpirole-induced repetitive behavior in rats. J Psychopharmacol 2010, 1-8.
    • (2010) J Psychopharmacol , pp. 1-8
    • de Haas, R.1    Nijdam, A.2    Westra, T.A.3    Kas, M.J.H.4    Westenberg, H.G.M.5
  • 17
    • 0035049083 scopus 로고    scopus 로고
    • N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury
    • Demougeot C., Garnier Pl, Mossiat C., Bertrand N., Giroud M., Beley A., Marie C. N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury. J Neurochem 2001, 77(2):408-415.
    • (2001) J Neurochem , vol.77 , Issue.2 , pp. 408-415
    • Demougeot, C.1    Garnier, P.2    Mossiat, C.3    Bertrand, N.4    Giroud, M.5    Beley, A.6    Marie, C.7
  • 18
    • 33745610137 scopus 로고    scopus 로고
    • Correlation of brain magnetic resonance imaging changes with pallidal manganese concentrations in rhesus monkeys following subchronic manganese inhalation
    • Dorman C.D., Struve M.F., Wong A.W., Dye J.A., Robertson I.D. Correlation of brain magnetic resonance imaging changes with pallidal manganese concentrations in rhesus monkeys following subchronic manganese inhalation. Toxicol Sci 2006, 92(1):219-227.
    • (2006) Toxicol Sci , vol.92 , Issue.1 , pp. 219-227
    • Dorman, C.D.1    Struve, M.F.2    Wong, A.W.3    Dye, J.A.4    Robertson, I.D.5
  • 19
    • 54349089416 scopus 로고    scopus 로고
    • Metabolomic analyses of body fluids after subchronic manganese inhalation in rhesus monkeys
    • Dorman C.D., Struve M.F., Norris A., Higgings A.J. Metabolomic analyses of body fluids after subchronic manganese inhalation in rhesus monkeys. Toxicol Sci 2008, 106(1):46-54.
    • (2008) Toxicol Sci , vol.106 , Issue.1 , pp. 46-54
    • Dorman, C.D.1    Struve, M.F.2    Norris, A.3    Higgings, A.J.4
  • 20
    • 2442423090 scopus 로고    scopus 로고
    • Globus pallidus: a target region for divalent metal accumulation associated with dietary iron deficiency
    • Erikson K.M., Syversen T., Steinnes E., Aschner M. Globus pallidus: a target region for divalent metal accumulation associated with dietary iron deficiency. J Nutr Biochem 2004, 15:335-341.
    • (2004) J Nutr Biochem , vol.15 , pp. 335-341
    • Erikson, K.M.1    Syversen, T.2    Steinnes, E.3    Aschner, M.4
  • 21
    • 34447561801 scopus 로고    scopus 로고
    • Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity
    • Erikson K.M., Dorman D.C., Lash L.H., Aschner M. Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity. Toxicol Sci 2007, 97(2):459-466.
    • (2007) Toxicol Sci , vol.97 , Issue.2 , pp. 459-466
    • Erikson, K.M.1    Dorman, D.C.2    Lash, L.H.3    Aschner, M.4
  • 23
    • 33645867691 scopus 로고    scopus 로고
    • The effects of manganese on glutamate, dopamine and γ-aminobutyric acid regulation
    • Fitsanakis V.A., Au C., Erikson K.M., Aschner M. The effects of manganese on glutamate, dopamine and γ-aminobutyric acid regulation. Neurochem Int 2006, 48:426-433.
    • (2006) Neurochem Int , vol.48 , pp. 426-433
    • Fitsanakis, V.A.1    Au, C.2    Erikson, K.M.3    Aschner, M.4
  • 24
    • 42149094924 scopus 로고    scopus 로고
    • Measuring brain manganese and iron accumulation in rats following 14weeks of low-dose manganese treatment using atomic absorption spectroscopy and magnetic resonance imaging
    • Fitsanakis V.A., Zhang N., Anderson J.G., Erikson K.M., Avison M.J., Gore J.C., Aschner M. Measuring brain manganese and iron accumulation in rats following 14weeks of low-dose manganese treatment using atomic absorption spectroscopy and magnetic resonance imaging. Toxicol Sci 2008, 103(1):116-124.
    • (2008) Toxicol Sci , vol.103 , Issue.1 , pp. 116-124
    • Fitsanakis, V.A.1    Zhang, N.2    Anderson, J.G.3    Erikson, K.M.4    Avison, M.J.5    Gore, J.C.6    Aschner, M.7
  • 25
    • 34250015267 scopus 로고    scopus 로고
    • Quantifying the psychomotor activating effects of cocaine in the rat
    • Flagel S.B., Robinson T.E. Quantifying the psychomotor activating effects of cocaine in the rat. Behav Pharmacol 2007, 18:297-302.
    • (2007) Behav Pharmacol , vol.18 , pp. 297-302
    • Flagel, S.B.1    Robinson, T.E.2
  • 26
    • 78049474862 scopus 로고    scopus 로고
    • Manganese exposure inhibits the clearance of extracellular GABA and influences taurine homeostasis in the striatum of developing rats
    • Fordahl S.C., Anderson J.G., Cooney P.T., Weaver T.L., Colyer C.L., Erikson K.M. Manganese exposure inhibits the clearance of extracellular GABA and influences taurine homeostasis in the striatum of developing rats. NeuroTox 2010, 31:639-646.
    • (2010) NeuroTox , vol.31 , pp. 639-646
    • Fordahl, S.C.1    Anderson, J.G.2    Cooney, P.T.3    Weaver, T.L.4    Colyer, C.L.5    Erikson, K.M.6
  • 27
    • 33745801577 scopus 로고    scopus 로고
    • A manganese-enhanced diet alters brain metals and transporters in the developing rat
    • Garcia S.J., Gellein K., Syversen T., Aschner M. A manganese-enhanced diet alters brain metals and transporters in the developing rat. Toxicol Sci 2006, 92(2):516-525.
    • (2006) Toxicol Sci , vol.92 , Issue.2 , pp. 516-525
    • Garcia, S.J.1    Gellein, K.2    Syversen, T.3    Aschner, M.4
  • 28
    • 0020409969 scopus 로고
    • Alterations in brain dopamine and GABA following inorganic or organic manganese administration
    • Gianutsos G., Murray M.T. Alterations in brain dopamine and GABA following inorganic or organic manganese administration. NeuroTox 1982, 3:75-81.
    • (1982) NeuroTox , vol.3 , pp. 75-81
    • Gianutsos, G.1    Murray, M.T.2
  • 30
    • 13244249953 scopus 로고    scopus 로고
    • Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS
    • Halket J.M., Waterman D., Przyborowska A.M., Patel R.K.P., Fraser P.D., Bramley P.M. Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS. J Exp Bot 2005, 56(410):219-243.
    • (2005) J Exp Bot , vol.56 , Issue.410 , pp. 219-243
    • Halket, J.M.1    Waterman, D.2    Przyborowska, A.M.3    Patel, R.K.P.4    Fraser, P.D.5    Bramley, P.M.6
  • 35
    • 73449128308 scopus 로고    scopus 로고
    • Preweaning manganese exposure causes hyperactivity, disinhibition, and spatial learning and memory deficits associated with altered dopamine receptor and transporter levels
    • Kern C.H., Stanwood G.D., Smith D.R. Preweaning manganese exposure causes hyperactivity, disinhibition, and spatial learning and memory deficits associated with altered dopamine receptor and transporter levels. Synapse 2010, 64:363-378.
    • (2010) Synapse , vol.64 , pp. 363-378
    • Kern, C.H.1    Stanwood, G.D.2    Smith, D.R.3
  • 36
    • 0033012435 scopus 로고    scopus 로고
    • Positron emission tomography (PET) in differentiating manganism from idiopathic Parkinsonism
    • Kim Y., Kim J.W., Ito K., Hisanaga N., Cheong H.K., Kim K.S., Moon Y. Positron emission tomography (PET) in differentiating manganism from idiopathic Parkinsonism. J Occup Health 1999, 41:91-94.
    • (1999) J Occup Health , vol.41 , pp. 91-94
    • Kim, Y.1    Kim, J.W.2    Ito, K.3    Hisanaga, N.4    Cheong, H.K.5    Kim, K.S.6    Moon, Y.7
  • 37
    • 39549102648 scopus 로고    scopus 로고
    • Metabolimics in biomarker discovery: future uses for cancer prevention
    • Kim Y.S., Maruvada P., Milner J.A. Metabolimics in biomarker discovery: future uses for cancer prevention. Future Oncol 2008, 4(1):93-102.
    • (2008) Future Oncol , vol.4 , Issue.1 , pp. 93-102
    • Kim, Y.S.1    Maruvada, P.2    Milner, J.A.3
  • 38
    • 84856235794 scopus 로고
    • NTP, Toxicology and carcinogenesis studies of manganese (II) sulfate monohydrate in F344/N rats and B6C3F1 mice (feed study)
    • NTP Toxicology and carcinogenesis studies of manganese (II) sulfate monohydrate in F344/N rats and B6C3F1 mice (feed study). National toxicology program. Technical report series 428. RISKLINE 94030007 1993.
    • (1993) National toxicology program. Technical report series 428. RISKLINE 94030007
  • 39
    • 0029905265 scopus 로고    scopus 로고
    • Clinical neurologic indices of toxicity in animals
    • O'Donoghue J.L. Clinical neurologic indices of toxicity in animals. Environ Health Perspect 1996, 104(Suppl. 2):323-330.
    • (1996) Environ Health Perspect , vol.104 , Issue.SUPPL. 2 , pp. 323-330
    • O'Donoghue, J.L.1
  • 40
    • 33746819836 scopus 로고    scopus 로고
    • Metabolomic approaches to phenotype characterization and applications to complex diseases
    • Oresic M., Vidal-Puig A., Hanninen V. Metabolomic approaches to phenotype characterization and applications to complex diseases. Expert Rev Mol Diagn 2006, 6(4):575-585.
    • (2006) Expert Rev Mol Diagn , vol.6 , Issue.4 , pp. 575-585
    • Oresic, M.1    Vidal-Puig, A.2    Hanninen, V.3
  • 41
    • 0033002368 scopus 로고    scopus 로고
    • Manganese neurotoxicity: a review of clinical features, imaging and pathology
    • Pal P.K., Samii A., Calne D.B. Manganese neurotoxicity: a review of clinical features, imaging and pathology. NeuroTox 1999, 20:227-238.
    • (1999) NeuroTox , vol.20 , pp. 227-238
    • Pal, P.K.1    Samii, A.2    Calne, D.B.3
  • 42
    • 77950369068 scopus 로고    scopus 로고
    • An optimized procedure for metabonomic analysis of rat liver tissue using gas chromatography/time-of-flight mass spectrometry
    • Pan L., Qiu Y., Chen T., Lin J., Chi Y., Su M., Zhao A., Jia W. An optimized procedure for metabonomic analysis of rat liver tissue using gas chromatography/time-of-flight mass spectrometry. J Pharm Biomed Anal 2010, 52(4):589-596.
    • (2010) J Pharm Biomed Anal , vol.52 , Issue.4 , pp. 589-596
    • Pan, L.1    Qiu, Y.2    Chen, T.3    Lin, J.4    Chi, Y.5    Su, M.6    Zhao, A.7    Jia, W.8
  • 43
    • 35448979511 scopus 로고    scopus 로고
    • Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons
    • Patil S., Melrose J., Chan C. Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons. Eur J Neurosci 2007, 26:2131-2141.
    • (2007) Eur J Neurosci , vol.26 , pp. 2131-2141
    • Patil, S.1    Melrose, J.2    Chan, C.3
  • 44
    • 76549105069 scopus 로고    scopus 로고
    • Brain region-specificity of palmitic acid-induced abnormalities associated with Alzheimer's disease
    • Patil S., Balu D., Melrose J., Chan C. Brain region-specificity of palmitic acid-induced abnormalities associated with Alzheimer's disease. BMC Res Notes 2008, 1:20.
    • (2008) BMC Res Notes , vol.1 , pp. 20
    • Patil, S.1    Balu, D.2    Melrose, J.3    Chan, C.4
  • 45
    • 34548364091 scopus 로고    scopus 로고
    • The neuropathology of manganese-induced Parkinsonism
    • Perl D.P., Olanow C.W. The neuropathology of manganese-induced Parkinsonism. J Neuropathol Exp Neurol 2007, 66(8):675-682.
    • (2007) J Neuropathol Exp Neurol , vol.66 , Issue.8 , pp. 675-682
    • Perl, D.P.1    Olanow, C.W.2
  • 46
    • 67650480216 scopus 로고    scopus 로고
    • Biomarkers in amyotrophic lateral sclerosis: facts and future horizons
    • Pradat P.F., Dib M. Biomarkers in amyotrophic lateral sclerosis: facts and future horizons. Mol Diagn Ther 2009, 13(2):115-125.
    • (2009) Mol Diagn Ther , vol.13 , Issue.2 , pp. 115-125
    • Pradat, P.F.1    Dib, M.2
  • 48
    • 33646176405 scopus 로고    scopus 로고
    • Neurotransmitters of the suprachiasmatic nuclei
    • Reghunandanan V., Reghunandanan R. Neurotransmitters of the suprachiasmatic nuclei. J Circadian Rhythm 2006, 4(2):1-20.
    • (2006) J Circadian Rhythm , vol.4 , Issue.2 , pp. 1-20
    • Reghunandanan, V.1    Reghunandanan, R.2
  • 49
    • 0030819919 scopus 로고    scopus 로고
    • Elastic fiber during development and aging
    • Ronchetti I.P., Contri M.B. Elastic fiber during development and aging. Microsc Res Tech 1997, 38:428-435.
    • (1997) Microsc Res Tech , vol.38 , pp. 428-435
    • Ronchetti, I.P.1    Contri, M.B.2
  • 50
    • 0038547086 scopus 로고    scopus 로고
    • Cardiovascular control by the suprachiasmatic nucleus: neural and neuroendocrine mechanisms in human and rat
    • Scheer F.A., Kalsbeek A., Buijs R.M. Cardiovascular control by the suprachiasmatic nucleus: neural and neuroendocrine mechanisms in human and rat. Biol Chem 2003, 384:697-709.
    • (2003) Biol Chem , vol.384 , pp. 697-709
    • Scheer, F.A.1    Kalsbeek, A.2    Buijs, R.M.3
  • 51
    • 33750340904 scopus 로고    scopus 로고
    • Effects of chronic manganese exposure on cognitive and motor functioning in non-human primates
    • Schneider J.S., Decamp E., Koser A.J., Fritz S., Gonczi H., Syversen T., Guilarte T.R. Effects of chronic manganese exposure on cognitive and motor functioning in non-human primates. Brain Res 2006, 1118(1):222-231.
    • (2006) Brain Res , vol.1118 , Issue.1 , pp. 222-231
    • Schneider, J.S.1    Decamp, E.2    Koser, A.J.3    Fritz, S.4    Gonczi, H.5    Syversen, T.6    Guilarte, T.R.7
  • 52
    • 0014823863 scopus 로고
    • Differences between manganese and magnesium ions with regard to fatty acid biosynthesis, acetyl-coenzyme a carboxylase activity and malonyl-coenzyme A decarboxylation
    • Scorpio R.M., Masoro E.J. Differences between manganese and magnesium ions with regard to fatty acid biosynthesis, acetyl-coenzyme a carboxylase activity and malonyl-coenzyme A decarboxylation. Biochem J 1970, 118:391-399.
    • (1970) Biochem J , vol.118 , pp. 391-399
    • Scorpio, R.M.1    Masoro, E.J.2
  • 54
    • 33846917641 scopus 로고    scopus 로고
    • The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases
    • Steele A.D., Jackson W.S., King O.D., Lindquist S. The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases. PNAS 2007, 104:1983-1988.
    • (2007) PNAS , vol.104 , pp. 1983-1988
    • Steele, A.D.1    Jackson, W.S.2    King, O.D.3    Lindquist, S.4
  • 55
    • 80053473412 scopus 로고    scopus 로고
    • Sleep disturbances associated with Parkinson's disease
    • 219056
    • Suzuki K., Miyamoto M., Miyamoto T., Iwanami M., Hirata K. Sleep disturbances associated with Parkinson's disease. Park Dis 2011, 2011(219056):1-10.
    • (2011) Park Dis , vol.2011 , pp. 1-10
    • Suzuki, K.1    Miyamoto, M.2    Miyamoto, T.3    Iwanami, M.4    Hirata, K.5
  • 56
    • 33748862617 scopus 로고    scopus 로고
    • Manganese suppresses ATP-dependent intercellular calcium waves in astrocyte networks through alteration of mitochondrial and endoplasmic reticulum calcium dynamics
    • Tjalkens R.B., Zoran M.J., Mohl B., Barhoumi R. Manganese suppresses ATP-dependent intercellular calcium waves in astrocyte networks through alteration of mitochondrial and endoplasmic reticulum calcium dynamics. Brain Res 2006, 1113:210-219.
    • (2006) Brain Res , vol.1113 , pp. 210-219
    • Tjalkens, R.B.1    Zoran, M.J.2    Mohl, B.3    Barhoumi, R.4
  • 58
    • 0035893528 scopus 로고    scopus 로고
    • GABA-induced current and circadian regulation of chloride in neurones of the rat suprachiasmatic nucleus
    • Wagner S., Sagiv N., Yarom Y. GABA-induced current and circadian regulation of chloride in neurones of the rat suprachiasmatic nucleus. J Physiol 2001, 537(3):853-869.
    • (2001) J Physiol , vol.537 , Issue.3 , pp. 853-869
    • Wagner, S.1    Sagiv, N.2    Yarom, Y.3
  • 60
    • 0033662853 scopus 로고    scopus 로고
    • The neurobehavioral effects of subchronic manganese exposure in the presence and absence of pre-parkinsonism
    • Witholt R., Gwiazda R.H., Smith D.R. The neurobehavioral effects of subchronic manganese exposure in the presence and absence of pre-parkinsonism. Neurotoxicol Teratol 2000, 22:851-861.
    • (2000) Neurotoxicol Teratol , vol.22 , pp. 851-861
    • Witholt, R.1    Gwiazda, R.H.2    Smith, D.R.3
  • 61
    • 0022400192 scopus 로고
    • Iron deficiency induces reversal of dopamine dependent circadian cycles: differential resonse to d-amphatamine and TRH
    • Youdim M.B., Yehuda S. Iron deficiency induces reversal of dopamine dependent circadian cycles: differential resonse to d-amphatamine and TRH. Peptides 1985, 6:851-855.
    • (1985) Peptides , vol.6 , pp. 851-855
    • Youdim, M.B.1    Yehuda, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.