An optimized procedure for metabonomic analysis of rat liver tissue using gas chromatography/time-of-flight mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 4, 2010, Pages 589-596

  Pan, Li ^a   Qiu, Yunping ^b   Chen, Tianlu ^a   Lin, Jinchao ^c   Chi, Yi ^c   Su, Mingming ^d   Zhao, Aihua ^c   Jia, Wei ^a,b  

^a Shanghai Jiao Tong University   (China)

^b UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

^d David H Murdock Research Institute   (United States)

Author keywords

Carbon tetrachloride; Gas chromatography time of flight mass spectrometry; Liver tissue; Metabonomics; Multivariate statistics

Indexed keywords

CARBON TETRACHLORIDE; CHLOROFORM; METHANOL; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMICS; CALIBRATION; CONTROLLED STUDY; GAS CHROMATOGRAPHY; LIVER INJURY; LIVER PARENCHYMA; MALE; METABONOMICS; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RAT; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SOLVENT EXTRACTION; TIME OF FLIGHT MASS SPECTROMETRY; VALIDATION PROCESS; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; LIVER; MASS FRAGMENTOGRAPHY; METABOLISM; METABOLOMICS; PROCEDURES; RANDOMIZATION; SPRAGUE DAWLEY RAT;

ANIMALS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LIVER; MALE; METABOLOMICS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77950369068     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.01.046     Document Type: Article

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