Fluorinated N, N-dialkylaminostilbenes repress colon cancer by targeting methionine S-Adenosyltransferase 2A

ACS Chemical Biology

Volumn 8, Issue 4, 2013, Pages 796-803

  Zhang, Wen ^a,d   Sviripa, Vitaliy ^a,c   Chen, Xi ^a,d   Shi, Jiandang ^a,d   Yu, Tianxin ^a,d   Hamza, Adel ^b   Ward, Nicholas D ^a   Kril, Liliia M ^a,d   Vander Kooi, Craig W ^a   Zhan, Chang Guo ^b   Evers, B Mark ^a,d   Watt, David S ^a,c,d   Liu, Chunming ^a,d  

^a UNIVERSITY OF KENTUCKY   (United States)

^b University of Kentucky   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; METHIONINE ADENOSYLTRANSFERASE; METHIONINE ADENOSYLTRANSFERASE 2A; METHIONINE ADENOSYLTRANSFERASE 2B; N,N DIALKYLAMINOSTILBENE DERIVATIVE; S ADENOSYLMETHIONINE; SHORT HAIRPIN RNA; STILBENE DERIVATIVE; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOTINYLATION; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; TUMOR XENOGRAFT;

ANIMALS; BIOCATALYSIS; COLONIC NEOPLASMS; FLUORINE; HUMANS; METHIONINE ADENOSYLTRANSFERASE; MICE; MODELS, MOLECULAR; STILBENES; TRANSPLANTATION, HETEROLOGOUS;

MUS MUSCULUS;

EID: 84876549015     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb3005353     Document Type: Article

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